Shofa Chasani
Nefrologi-Hipertensi Division, Master Program of Biomedical Science, Medical Faculty of UNDIP

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DIFFERENCE IN THE LEVELS OF FERRITIN, HEMOGLOBIN, AND ERYTHROCYTE COUNT OF STAGE 5 CHRONIC KIDNEY DISEASE PATIENTS AFTER ONE, THREE AND SIX MONTHS OF HEMODIALYSIS Wibowo, Subur; Chasani, Shofa; Wahyu W, Joko; Nasihun, Taufiqurrachman
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 10, No 1 (2019): January - June 2019
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26532/sainsmed.v10i1.2445

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Background: 77,892 chronic kidney disease patients in Indonesia undergo hemodialysis in 2017. However, the effects of period of undergoing hemodialysis on hemoglobin level, erythrocyte count, and ferritin level are still unclear. Objective: This research aims at examining the effects of period of undergoing hemodialysis on the levels of ferritin, hemoglobin, and erythrocyte count of stage 5 of chronic kidney disease patients.Methods: In the analytical observational research with a cross sectional design, 30 men meet the inclusion criteria and are randomly divided into 3 groups: one month group (1M-G), three months group (3M-G), and six months group (6M-G). Each of the research objects has undergone hemodialysis for one, three and six months. The levels of ferritin, hemoglobin, and erythrocyte count are analyzed with an immunoflourescence method.Results: The Post Hoc LSD analysis states that the ferritin levels of 3M-G (718±63.61) and 6M-G (947±66.22) are significantly higher than that of 1M-G (383.77), p< 0.01. The ferritin level of 6M-G is significantly higher than that of 3M-G, p<0.01. The hemoglobin levels and erythrocyte counts between 1M-G (9.45±0.84) & (3.26±0.55), 3M-G (9.10±1.22) & (3.21±0.50) and 6M-G (8.35±1.21) & (2.92±0.40) are insignificant, p>0.05.Conclusion: After undergoing hemodialysis for three and six months, the ferritin levels improve significantly compared to that of one month of hemodialysis, and there is no significant difference in hemoglobin levels and erythrocyte counts.Keywords: Hemodialysis, Ferritin, Erythrocyte, Hemoglobin
PENGARUH KEDALAMAN MENYELAM, LAMA MENYELAM, ANEMIA TERHADAP KEJADIAN PENYAKIT DEKOMPRESI PADA PENYELAM TRADISIONAL Duke, Halena Isrumanti; Widyastuti, Sri Rahayu; Hadisaputro, Suharyo; Chasani, Shofa
Jurnal Kesehatan Masyarakat Indonesia Volume 12. No. 2. Tahun 2017
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Latar Belakang:Penyakit dekompresi adalah suatu penyakit yang disebabkan oleh pelepasan dan pengembangan gelembung-gelembung gas dari fase larut dalam darah atau jaringan akibat penurunan tekanan dengan cepat di sekitarnya. Faktor-faktor yang diduga meningkatkan dekompresi adalah kedalaman menyelam, lama menyelam, dan anemia.Tujuan :Untuk menjelaskan besarnya pengaruh kedalaman menyelam, lama menyelam, anemia terhadap kejadian penyakit dekompresi pada penyelam tradisional. Metode :Penelitian mix methode desain studi kasus kontrol yang diperkuat dengan  indepth interview ini dilakukan terhadap 46 responden, meliputi 23 kasus (penyelam tradisional penderita penyakit dekompresi) dan 23 kontrol (penyelam tradisional bukan penderita penyakit dekompresi) yang diambil secara purposive sampling. Instrument penelitian adalah  kuesioner wawancara. Analisis data secara univariat, bivariat (chi-square), dan multivariat (logistic regression).Hasil :Kedalaman  menyelam  ? 30 meter (OR = 6,62; 95% CI = 1,059 ? 41,390, p<0.043), lama menyelam ? 2 jam (OR = 61,680; 95% CI = 3,687 ? 1031,93, p<0.004) dan anemia (OR = 14,453, 95% CI = 2,146-97,346, p<0.006) berpengaruh terhadap kejadian penyakit dekompresi.Kesimpulan :Kedalaman  menyelam ? 30 meter, lama menyelam  ? 2 jam, dan anemia berpengaruh terhadap kejadian penyakit dekompresi dengan probabilitas 94,45%.
KORELASI RASIO NEUTROFIL/LIMFOSIT DENGAN HANDGRIP STRENGTH PADA PENYAKIT GINJAL KRONIK TAHAP AKHIR Sriyani, Sriyani; Sulchan, Muhammad; Chasani, Shofa
JNH (Journal of Nutrition and Health) Vol 6, No 2 (2018): JOURNAL OF NUTRITION AND HEALTH
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (585.672 KB) | DOI: 10.14710/jnh.6.2.2018.85-92

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Latar belakang : Pada PGK tahap akhir biasa terjadi malnutrisi energi protein. Inflamasi yangberkelanjutan akan mempengaruhi status gizi, massa dan kekuatan otot yang diukur dengan HGS.Salah satu indikator inflamasi adalah rasio neutrofil/limfosit. Secara teoritik ada hubungan negatifantara rasio neutrofil/limfosit dan handgrip strength. Tujuan: Membuktikan adanya korelasi negatif rasio neutrofil/limfosit dengan HGS pada penyakitginjal kronik tahap akhir. Metode penelitian : Penelitian korelasional ini, dilakukan di unit hemodialisa RSUP Dr. KariadiSemarang selama bulan November 2016. Subyek 40 orang, ditetapkan dengan metode consecutivesampling, diwawancara dan menjalani pemeriksaan antropometri, HGS, pemeriksaanlaboratorium darah. Uji korelasi dilakukan dengan Uji Spearman. Hasil : NLR normal pada laki-laki 52,5 % dan perempuan 15 %. NLR buruk pada laki-laki 17,5 %dan perempuan 15 %. HGS normal pada laki-laki 7,5 % dan rendah 60%. Kategori HGS normalpada perempuan 12,5% dan HGS rendah sebanyak 20%. Nilai HGS terendah subyek laki-laki danperempuan adalah 14 kg/f dan tertinggi 34 kg/f dan 24 kg/f. Uji Spearman menunjukkan tidak adakorelasi antara rasio neutrofil/limfosit dengan HGS (r= 0,27, p=0,08). Simpulan : Korelasi negatif antara nilai handgrip strength dan rasio neutrofil/limfosit tidakdapat dibuktikan. Kata kunci :rasio neutrofil/limfosit, HGS, penyakit ginjal kronik
Comparison Between Taichi Chuan and Jacobson’s Progressive Muscular Relaxation in Decreasing Cortisol Concentration on Pre-Hypertension Patients Kesoema, Tanti Ajoe; Chasani, Shofa; Chasani, Shofa; Handoyo, Rudy; Handoyo, Rudy
Jurnal Kesehatan Masyarakat Vol 12, No 1 (2016): JURNAL KESEHATAN MASYARAKAT (KEMAS) JULY 2016
Publisher : Jurusan Ilmu Kesehatan Masyarakat Fakultas Ilmu Keolahragaan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v12i1.3988

Abstract

Nowadays, the prevalence of hypertension and its concomitant risk of cardiovascular and kidney disease development is increasing as the disability evidence in the society also rises. One of the potential risk factors of prehypertension is anxiety and it has already well-known that cortisol is a marker of anxiety. There are some nonpharmacologic methods to relieve anxiety: exercise and relaxation. Taichi Chuan is a low intensity aerobic exercise that also gives a relaxation effect.This study is organised to find out the effect of Taichi Chuan (TCC) and Jacobson’s Progressive Muscular Relaxation (JPMR) on cortisol level in pre hypertension patients. This is a pre and post-test design study with a total of 26 pre hypertension patients included. They were randomly divided into 2 groups. Group I performed Taichi Chuan exercise, while group II performed JPMR for 18 times. The intervention frequency was 3x/week for 6 weeks with 30 minutes duration for each session. In the study, which was held in April-June 2015, there was a decrease but no significant difference of cortisol concentration in both group.The comparison between groups also did not show statistical difference. However there were significant difference noted on the blood pressure before and after intervention in both groups.
Comparison Between Taichi Chuan and Jacobson’s Progressive Muscular Relaxation in Decreasing Cortisol Concentration on Pre-Hypertension Patients Kesoema, Tanti Ajoe; Chasani, Shofa; Chasani, Shofa; Handoyo, Rudy; Handoyo, Rudy
Jurnal Kesehatan Masyarakat Vol 12, No 1 (2016): JURNAL KESEHATAN MASYARAKAT (KEMAS) JULY 2016
Publisher : Jurusan Ilmu Kesehatan Masyarakat Fakultas Ilmu Keolahragaan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v12i1.3988

Abstract

Nowadays, the prevalence of hypertension and its concomitant risk of cardiovascular and kidney disease development is increasing as the disability evidence in the society also rises. One of the potential risk factors of prehypertension is anxiety and it has already well-known that cortisol is a marker of anxiety. There are some nonpharmacologic methods to relieve anxiety: exercise and relaxation. Taichi Chuan is a low intensity aerobic exercise that also gives a relaxation effect.This study is organised to find out the effect of Taichi Chuan (TCC) and Jacobson’s Progressive Muscular Relaxation (JPMR) on cortisol level in pre hypertension patients. This is a pre and post-test design study with a total of 26 pre hypertension patients included. They were randomly divided into 2 groups. Group I performed Taichi Chuan exercise, while group II performed JPMR for 18 times. The intervention frequency was 3x/week for 6 weeks with 30 minutes duration for each session. In the study, which was held in April-June 2015, there was a decrease but no significant difference of cortisol concentration in both group.The comparison between groups also did not show statistical difference. However there were significant difference noted on the blood pressure before and after intervention in both groups.
ISLAMIC PRAYER IS EFFECTIVE TO REDUCE PAIN AND ANXIETY PATIENTS WITH ACUTE MYOCARDIAL INFARCTION IN ICVCU : A PILOT STUDY] Setiawan, Arif Adi; Chasani, Shofa; Mardiyono, Mardiyono
Jurnal LINK Vol 12, No 2 (2016): November 2016
Publisher : UPPM Politeknik Kesehatan Kementrian Kesehatan Semarang

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Abstract

Peak periods of pain and anxiety begins in the first 12 hours of entry ICVCU (Intensive Cardiovascular Care Unit) and improve after 48 hours until the patient was transferred to the ward. The study was to evaluate the efftects of Islamic Prayer in reducing pain and anxiety in patients with AMI in ICVCU. The study was A quasi experimental pre and post test design. The Samples were AMI patients hospitalized for 3 days. Islamic Prayer is composed by reciting Qur’an, prayer, and zikr. Pain was measured by the Numeric Rating Scale for Pain and anxiety was measured by the Numerical Rating Scale for Anxiety (NRSA). The data pain and anxiety were analysized by paired t-test. The findings show that there were significant reductions in mean pain scores and anxious before and after intervention after entering ICVCU Islamic Prayer interventions effectively reduce pain at 12 hours (t = 6.293, p = .000), 24 hours (t = 5.191, p = .000) and 48 hours after admission (t = 6.698, p = .000) and anxious 12 hours (t = 6.293, p = .000), 24 hours (t = 5.506, p = .000), 48 hours (t = 5.234, p = .000). which means that Islamic Prayer is effective to reduce pain and anxiety in patients with AMI in ICVCU.
PROBABILITAS PERILAKU SEDENTARI TERHADAP HIPERTENSI PADA PEGAWAI DAERAH PERIMETER PELABUHAN Oktaviarini, Eka; Hadisaputro, Suharyo; Chasani, Shofa
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 9 No 1 (2019): Januari
Publisher : LPPM STIKES KENDAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (100.949 KB) | DOI: 10.32583/pskm.9.1.2019.12-21

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Hipertensi adalah peningkatan tekanan darah sistol ?140 mmHg atau diastol ?90 mmHg. Hipertensi sering disebut the silent killer karena tidak menimbulkan gejala sehingga pengobatannya seringkali terlambat. Hipertensi merupakan salah satu penyakit yang berhubungan dengan pekerjaan. Pegawai menghabiskan waktu kurang lebih delapan jam sehingga tidak memiliki kebiasaan olahraga secara teratur. Perilaku sedentari merupakan perilaku yang berisiko terhadap salah satu penyakit pembuluh darah. Proporsi hipertensi berdasarkan survei deteksi dini penyakit tidak menular pada pegawai kantor di daerah perimeter adalah 33,68%. Penelitian ini merupakan penelitian observasional analitik menggunakan desain case control dengan jumlah 76 sampel terdiri dari 38 kasus dan 38 kontrol yang diambil secara consecutive sampling pada populasi pegawai perimeter pelabuhan yang tercatat dalam survei deteksi dini tahun 2017. Data dianalisis secara univariat, bivariat dan multivariat. Hasil statistik yang diperoleh adalah jenis kelamin (p=0,010; OR adjusted 6,179; 95%CI 1,553-24,587) dan perilaku sedentari (p=0,034; OR adjusted 0,338; 95%CI 0,124-0,921). Umur, riwayat keluarga, kebiasaan olahraga, riwayat stres kerja dan jadwal kerja tidak terbukti sebagai faktor risiko hipertensi. Hormon merupakan salah satu penyebab hipertensi pada laki-laki cenderung lebih tinggi. Otot seseorang yang kurang melakukan aktivitas fisik cenderung akan mengendor sehingga peredaran darah akan terhambat dan kerja jantung akan lebih berat. &nbsp; Kata kunci : Hipertensi, pegawai, pelabuhan, sedentari &nbsp; SELF-CONCEPT OF PATIENTS WITH CHRONIC RENAL FAILURE WHO UNDERWENT HEMODIALYSIS &nbsp; ABSTRACT Hypertension is an increase in systolic blood pressure ?140 mmHg or diastolic ?90 mmHg. Hypertension is often called the silent killer because it does not cause symptoms so the treatment is often late. Hypertension is a work-related disease. Officers spend approximately eight hours so they do not have regular exercise habits. Sedentary is a risky behavior for one of the vascular diseases. The proportion of hypertension based on early detection of non-communicable diseases in the perimeter area is 33,68%. This research is an analytic observational study using a case control design with 76 samples consisting of 38 cases and 38 controls taken by consecutive sampling in the population of port perimeter officers recorded in the early detection survey in 2017. Data were analyzed by univariate, bivariate and multivariate. Results obtained were gender (p=0,010; adjusted OR 6,179; 95%CI 1,553-24,587) and sedentary behavior (p=0,034; adjusted OR 0,338; 95%CI 0,124-0,921). Age, family history, exercise habits, history of work stress and work schedules are not proven to be risk factors of hypertension. Hormone is one of the causes of hypertension in men tend to be higher. The muscle of someone who is less physically active tends to relax so that blood circulation will be hampered and the heart will work harder. &nbsp; Keywords: Hypertension, officers, port, sedentary.
FAKTOR RISIKO KEJADIAN HIPERTENSI DI PUSKESMAS KENDURUAN, KABUPATEN TUBAN Santosa, Lingga Hageng Kurnia; Chasani, Shofa; Pramudo, Setyo Gundhi
DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO ) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO )

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Abstract

Latar Belakang : Salah satu penyakit tidak menular yang menjadi masalah kesehatan penting di seluruh dunia adalah hipertensi, dikarenakan prevalensinya yang tinggi dan terus meningkat serta hubungannya dengan penyakit kardiovaskuler, stroke, retinopati, dan penyakit ginja.Tujuan : Mengetahui hubungan faktor risiko hipertensi terhadap kejadian hipertensi derajat 1 dan derajat 2 pada Pasien yang berobat di Puskesmas Kenduruan , Kabupaten Tuban, Jawa Timur.Metode : Jenis penelitian ini adalah observasional analitik dengan pendekatan cross sectional. Subyek dalam penelitian ini berjumlah 75 responden yang menderita hipertensi. Penelitian dilakukan di Puskesmas Kenduruan, Kecamatan Kenduruan, Kabupaten Tuban pada bulan Maret 2016. Sampel diambil secara konsekutif sampling. Data diperoleh melalui kuesioner dan wawancara langsung serta pemeriksaan fisik berupa pengukuran tekanan darah, tinggi badan, dan berat badan. Analisis data dilakukan secara bertahap meliputi analisis univariat, analisis bivariat menggunakan uji Chi-square, dan analisis multivariat menggunakan uji regresi logistik berganda metode Backward Stepwise (Likelihood Ratio) pada program SPSS.Hasil : Hasil uji statistik dengan regresi logistik berganda tidak menunjukkan adanya perbedaan antara faktor risiko hipertensi stage I dan hipertensi stage II pada masyarakat di Puskesmas Kenduruan, Kecamatan Kenduruan, Kabupaten Tuban. Dengan riwayat keluarga (p = 0,586; OR = 1,36 dan 95% CI = 0,449 ? 4,117), usia ( p = 1,000; OR = 1,131 dan 95% CI = 0,27 ? 4,72), merokok (p = 1,000; OR = 0,94 dan 95% CI = 0,18 ? 5,05), obesitas (p = 0,749; OR = 1,18 dan 95% CI = 0,33 ? 4,28), jenis kelamin ( p = 0,725; OR = 0,69 dan 95% CI = 0,19 ? 2,54), konsumsi garam (p = 1,000; OR = 0,5 dan 95% CI = 0,06 ? 4,35), konsumsi lemak (p = 0,72; OR = 0,082 dan 95% CI = 0,11 ? 2,8 ), aktivitas fisik (p = 0,033; OR = 4,32; 95% CI = 1,28 ? 14,58 ) dan konsumsi alkohol (p = 1,000 ).Simpulan : Riwayat keluarga, usia, merokok, obesitas, jenis kelamin, konsumsi garam, konsumsi lemak, aktivitas fisik dan konsumsi alkohol tidak didapatkan hasil yang berbeda sebagai faktor-faktor risiko hipertensi stage I maupun hipertensi stage II.
FAKTOR RISIKO KEJADIAN HIPERTENSI PADA PASIEN YANG BEROBAT DI POLIKLINIK RSUD RAA SOEWONDO PATI Rachman, Reza; Chasani, Shofa; Pramudo, Setyo Gundi
DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO ) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO )

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Abstract

Latar Belakang : Hipertensi bukanlah penyakit yang dapat dipandang sebelah mata saja, sebab kondisi faktual menyatakan bahwa hipertensi dapat meningkatkan timbulnya beberapa komplikasi yaitu penyakit serebrovaskular, infark miokard, gagal jantung kongestif, dan insufisiensi renal. Hal tersebut akan menyebabkan disabilitas, membatasi aktivitas sehari-hari, fungsi sosial, dan status psikologis.Tujuan : Mengetahui hubungan faktor risiko hipertensi terhadap kejadian hipertensi stage 1 dan stage 2 pada pasien yang berobat di poliklinik RSUD RAA Soewondo Pati.Metode : Jenis penelitian ini adalah observasional analitik dengan pendekatan cross sectional. Subyek dalam penelitian ini berjumlah 75 responden, yang menderita hipertensi. Penelitian dilakukan di poliklinik RSUD RAA Soewondo Pati pada bulan Maret 2016. Sampel diambil secara consequtive sampling. Data diperoleh melalui kuesioner dan wawancara langsung serta pemeriksaan fisik berupa pengukuran tekanan darah, tinggi badan, dan berat badan. Analisis data dilakukan secara bertahap meliputi analisis univariat, analisis bivariat menggunakan uji Chi-square, dan analisis multivariat menggunakan uji regresi logistik berganda metode Backward Stepwise (Likelihood Ratio) pada program SPSS.Hasil : Hasil uji statistik dengan regresi logistik berganda tidak menunjukkan adanya perbedaan antara  faktor risiko hipertensi stage 1 dan hipertensi stage 2 pada pasien yang berobat di poliklinik RSUD RAA Soewondo Pati yaitu usia (p = 0,83), riwayat keluarga (p = 0,615), merokok (p = 0,222),  obesitas (p = 0,25), jenis kelamin (p = 0,713), konsumsi natrium ( p = 0,653), konsumsi lemak (p = 1), aktivitas (p = 0,673) dan alkohol (p = 0,606).Simpulan : Faktor risiko hipertensi usia, riwayat keluarga, merokok, obesitas, jenis kelamin, konsumsi natrium, konsumsi lemak, aktivitas dan konsumsi alkohol tidak menunjukkan perbedaan yang bermakna terhadap kejadian hipertensi stage 1 dan stage 2.
PERSEPSI PASIEN PENYAKIT GINJAL KRONIK YANG MENJALANI HEMODIALISIS TERHADAP PERMASALAHAN DISFUNGSI EREKSI Wahyuningtyas, Eka Sakti; Chasani, Shofa; Hidayati, Wahyu
Journal Of Holistic Nursing Science Vol 3 No 2 (2016)
Publisher : Universitas Muhammadiyah Magelang

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Chronic Kidney Disease is a disorder of renal function are progressive and irreversible. Male patients with Chronic Kidney Disease undergoing hemodialysis may have an experience with sexual dysfunction problems is erectile dysfunction. The problem of erectile dysfunction can be a complex psychosocial problems such as depression. Perceptions and expectations of patients with chronic kidney disease who undergoing hemodialysis with erectile dysfunction to sexual fulfillment nursing care needs to be known and have not been studied until now. The research had toexplore the experiences of patients with chronic kidney disease who undergoing hemodialysis with erectile dysfunction. Methods of the research is a qualitative research design with a phenomenological approach. Subjects were patients with chronic kidney disease who undergoing hemodialysis with erectile dysfunction in Hemodialysis Unit RS Tk II.04.05.01 Dr.Soedjono Magelang many as seven people The collection of data by means of indepth interviews. The study was conducted in February-April 2016. In this research have the three themes, the perception initial of the chronic kidney disease and erectile dysfunction, the factors that cause erectile dysfunction, attitudes and feelings the patients related to the condition of erectile dysfunction.Patients with chronic kidney disease who undergoing hemodialysis with erectile dysfunction have a perception that the condition of the disease and hemodialysis therapy effect on erectile dysfunction problems.