Tjokorda Gde Dharmayuda
Unknown Affiliation

Published : 3 Documents
Articles

Found 3 Documents
Search

GAMBARAN KUALITAS HIDUP PASIEN KANKER LIMFOMA NON HODGKIN YANG DIRAWAT DI RSUP SANGLAH DENPASAR (STUDI PENDAHULUAN) Sutrisno, Heri; Dharmayuda, Tjokorda Gde; Rena, Renny A
journal of internal medicine Vol. 11, No. 2 Mei 2010
Publisher : journal of internal medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Quality of life was a target therapy in cancer patients especially on metastatic cancer. Quality of life currently havebecomeone of stadard for therapeutic evaluation. Because quality of life was a subjectif characteristic and can only measure bypatient, so measuring quality of life patients must use multidimensional measure tool that offend aspect from physical, social andemotional, simple, easy to understand and answer by all patients and must to validated.To observe description of quality of life from cancer patient of Non Hodgkin Lymphoma (NHL) which admitted in SanglahHospital Denpasar, we have done analytic descriptive research on NHL patients with used EORTC QLQ-C30 questioner. Fifteenof NHL patients which cared in Internal Department Sanglah Hospital on January ? June 2010, 12 (80%) were male and 3 (20%)were female. Good quality of life was 8 (53.3%), moderate was 5 (33.3%) and poor was 2 (13.2%). From 10 (66.7%) patientsundergone chemotherapy, good quality of life was 5 (50%), moderate was 3 (30%) and poor was 2 (20%). There is correlationbetween quality of life of NHL patients with grading of clinical disease (p = 0.032; r = -0.554), there is no correlation qualityof life with giving chemotherapy in NHL patients (p = 0.560; r = -0.164). Meassuring quality of life NHL patient with EORTCQLQ-C30 was correlated with Karnofsky score (p = 0.031; r = 0.557) and ECOG (p = 0.04; r = -0.699).
TINGKAT HARAPAN HIDUP PASIEN LIMFOMA NON-HODGKIN BERDASARKAN SKOR IPI YANG MENDAPATKAN KEMOTERAPI LINI PERTAMA DI RSUP SANGLAH DENPASAR TAHUN 2014 Suryadiarsa, I Putu Dhidhi Pradnya; Rena, Ni Made Renny Anggraeni; Dharmayuda, Tjokorda Gde
E-Jurnal Medika Udayana Vol 8 No 5 (2019): Vol 8 No 5 (2019): Vol 8 No 5 (2019): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Limfoma Non-Hodgkin (LNH) merupakan penyakit hematologi dengan keganasan yangterjadi pada limfosit, disebabkan oleh abnormalitas dari perkembangan limfosit yang akanmembentuk suatu tumor, apabila dibiarkan maka dapat berkembang menjadi kanker. SkorInternational Prognostic Index (IPI) merupakan alat ukur yang digunakan untuk memperkirakantingkat harapan hidup pasien LNH secara multidimensional dengan beberapa komponen, yaituumur, stadium penyakit, kadar serum Lactate Dehydrogenase (LDH), keterlibatan ekstranodul,dan status kinerja. Penelitian ini dilakukan untuk mengetahui tingkat harapan hidup pasien LNHberdasarkan skor IPI yang mendapatkan kemoterapi lini pertama di RSUP Sanglah Denpasartahun 2014. Studi ini menggunakan metode penelitian deskriptif retrospektif terhadap pasienLNH di RSUP Sanglah Denpasar selama tahun 2014. Dari 25 pasien yang menjadi responden,memiliki rentang umur antara 61-76 tahun dengan rerata umur 65,68 + 4,7 tahun dan medianumur 65 tahun. Pasien lelaki berjumlah 19 orang dengan persentase 76%. Gejala klinis penyakitLNH ditandai dengan adanya benjolan (100%), demam (80%), penurunan berat badan (80%),lemas (80%), anemia (72%), dan keluhan organ (52%). Diffuse Large B-Cell Lymphoma(DLBCL) merupakan gambaran histopatologi tersering di RSUP Sanglah Denpasar denganpersentase 68%. Hasil skor IPI diantaranya empat pasien (16%) kategori low risk, dua pasien (8%)kategori low-intermediate risk, dua pasien (8%) kategori high-intermediate risk, dan 17 pasien(68%) kategori high risk. Sebagian besar kasus LNH di RSUP Sanglah Denpasar memilikiprognosis yang buruk, sehingga memiliki tingkat harapan hidup sebesar 34% dalam dua tahundan 26% dalam lima tahun.Kata kunci: Tingkat harapan hidup, Limfoma Non-Hodgkin, Skor IPI
KESULITAN DIAGNOSIS DAN TERAPI PADA LIMFOMA PANKREAS DISERTAI SINDROMA KAUDA EQUINA Ridwan, Muhammad; Dharmayuda, Tjokorda Gde
journal of internal medicine Vol. 9, No. 1 Januari 2008
Publisher : journal of internal medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Lymphoma, part of non-Hodgkin?s lymphoma, is a rare malignancy in pancreas. Its clinicalpresentations and supporting laboratory and imaging results are similar to those of pancreas adenocarcinoma.Apart from pancreas, extranodal type of non-Hodgkin can involve many other organs including bone marrows,nervous system, and kidneys. Treatment should be focused on emergency priority and the underlying cause. Inthis case report, we have documented a 44 year-old man who initially presented jaundice and abdominal massand then diagnosed with pancreas tumor. However, pathology anatomy and histochemistry examinations ofperipancreas tissue biopsy and indicated a non-hodgkin lymphoma of pancreas, in form of diffuse large B celllymphoma, intermediate grade. The patient was developing cauda equina syndrome a week after laparotomy.Discussion among team suggested that both conditions may have the same root: lymphoma. The patient wasthen put on CHOP regiments of chemotherapy program and later, also underwent a spinal decompressionprocedure. Overall, jaundice, abdominal mass and other related symptoms subsided, and quality of lifeimproved, although some cauda equina symptoms remained.