Aisyah Fatmawaty
Faculty of Pharmacy, Hasanuddin University, Makassar.

Published : 5 Documents
Articles

Found 5 Documents
Search

Formulasi Patch Ekstrak Etanol Daun Murbei (Morus Alba L.) dengan Variasi Konsentrasi Polimer Polivinil Pirolidon dan Etil Selulosa Fatmawaty, Aisyah; Nisa, Michrun; Irmayani, Irmayani; Sunarti, Sunarti
Jurnal Farmasi dan Ilmu Pengobatan Vol 2 No 1 (2017): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.809 KB)

Abstract

Patch formulation studies have been conducted mulberry leaf extract with various concentrations of polyvinyl pirilidon and ethyl cellulose (EC) obtain a patch with good physical characteristics. Physical evaluation includes weight, thickness, and folding endurance, loss on drying and moisture uptake. The results showed that the optimum formula by solvent evaporation method is F3 (PVP : EC = 200 : 400) with average weight (0,76±0.006 g), resilience fold (> 200), thickness (0.411±0.039 cm), drying shrinkage (38.12 > 9.29 ) and absorption (29.06 > 9.79 ).
Formulation and in vivo Effectiveness Test of Albumin Gel Isolated From White Egg As Anti-Aging Yusuf, Nurul Arfiyanti; Fatmawaty, Aisyah
Jurnal Farmasi dan Ilmu Pengobatan Vol 2 No 1 (2017): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.159 KB)

Abstract

The aim of this study was to find a stable formula of the albumin gel isolated from white egg. Albumin was formulated into 3 different concentration: F1 (1%), F2 (2%), and F3 (3%). Evaluation of gel was conducted after pass out the stress condition using an accelerated storage in the climatic chamber, temperature 5°C to 35°C, 75% RH, for 12 hours, 10 cycles. Physical stability including organoleptic, homogeneity, pH, viscosity, spread ability, and adhesion ability were observed before and after storage. While, on effectiveness test use 3 volunteers (age> 30 years), not using any other cosmetics and not allergic to eggs. The gel was applied to the back of them left hand twice a day for 3 months and compared with that right hand (without using the gel). The results showed that all formula required a physically stable and F3 (3%) most effectivelly and significantly to incerease the skin moisture (p> 0.05). In conlusion, albumin isolated from white egg can be formulated into a gel as anti-aging.
The Effect of Sodium Alginate on the Physical Characteristics of Mulberry (Morus alba L.) Leaf Extract Fatmawaty, Aisyah; Riski, Radhia; Arfiyanti, Nurul; Muslimin, Lukman
Jurnal Farmasi dan Ilmu Pengobatan Vol 2 No 2 (2017): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (432.757 KB)

Abstract

The research about the effects of sodium alginate as the polymer to found a stable physical characteristic of microparticles of mulberry leaves (Morus alba L) has been conducted. The purpose of this study was to determine the effect of Na.alginate as the polymer to the physical characteristics of microparticles of M.alba. In this research, the formulation M. alba leaves  in the form of microparticles in which the sodium alginate as a polymer with cross connector CaCl2. Microparticles with an ionic gelation method by dispersing mulberry leaf-sodium alginate into a solution of CaCl2. Formula microparticles made with mulberry leaves concentration ratio of sodium alginate (1: 1); (1: 1.5), and (1: 2). Microparticles characterized physically by the size, shape, and appearance by using SEM (scanning electron microscopy), and the adsorption efficiency. The yield on mulberry leaves microparticles obtained are not spherical morphology SEM and entrapment efficiency data cannot be calculated.
Anti-Collagenase Activity of Extract of Brokoli (Brassica oleocera L. var italica), Carrot (Daucus carota L.) and Chili pepper (Capsicum annuum L.) Fatmawaty, Aisyah; Angriani, Angriani
Jurnal Farmasi dan Ilmu Pengobatan Vol 3 No 2 (2018): JPMS
Publisher : STIFA Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32814/jpms.v3i2.71

Abstract

Collagenase is an enzyme family of Matrix Metalloproteinase (MMP) that breaks down collagen and degrade the extracellular matrix resulting in wrinkles and changes in skin thickness. This study was aimed to determine the value of inhibition concentration of flower extracts of broccoli (Brassica oleocera L. var Italica), carrot extract (Daucus Carota L.) and extract of chili pepper (Capsicum annuum L.) as collagenase inhibitor. Collagenase inhibitory activity was determined by measuring the product resulted from the reaction of enzyme and substrate using a microplate reader at ? 345 nm. Results showed that the inhibition of the flowers of broccoli, carrot and chili pepper ekstrak were 88.49%; 53.96% and 89.21% at a concentration of 250 ug / ml.
PENGARUH ISOPROPIL MYRISTAT SEBAGAI BAHAN PENINGKAT PENETRASI TERHADAP LAJU DIFUSI KRIM PEMUTIH EKSTRAK ETANOL DAUN MURBEI (Morus alba L) Yusuf, Nurul Arfiyanti; Fatmawaty, Aisyah
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.773 KB)

Abstract

The research has conducted research on the effectiveness of isopropyl myristat as a penetration enhancer on the diffusion rate of whitening cream mulberry leaf extract (Morus alba L) in vitro. This study aims to determine the effect of the use of isopropyl myristat. Mulberry leaf extract cream made with varying concentrations respectively 3%, 4%, 5% Isopropyl myristat as penetration enhancers made into 3 formulas (F1-F4) with the F1 without penetration enhancers. Evaluation of stability before and after accelerated storage includes observation of the organoleptic, emulsion type determination, measurement of pH, and viscosity. The evaluation results indicate four physically stable formula. In vitro diffusion studies conducted by Franz diffusion cells and footage is measured at a wavelength of 367.4 nm. The results of diffusion studies show that formula with the highest diffusion rate of 0.024 µg/minute on F4 (5% isopropyl myristat).