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Review: Tumbuhan Duku: Senyawa Bioaktif, Aktivitas Farmaklogis dan Prospeknya dalam Bidang Kesehatan Hanum, Laila; Kasiamdari, Rina S.
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Publisher : Jurnal Biologi Papua

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Abstract

Lansium domesticum Corr. (Meliaceae) is the popular tropical plant producing economic edible fruits found mainly in Southeast Asia. Seed, leaf, bark, stalks and fruit skin extracts of this plant are potential sources for compounds with broad spectrum of pharmacological activities such as antitumor, anticancer, antimalaria, antimelanogenesis, antibacteria and it may lead to the discovery of a new compouds used for antimutagenic and antioxidative stress. Bioactive compounds, pharmacological activities and prospect this plant in medical application will be discussed in this paper.Key words: Lansium domesticum, bioactive compounds, pharmacological activities, medical application.
Patofisiologi Bisa Ular dan Aplikasi Terapi Tumbuhan Obat Antiophidia (Antibisa) Karim, Aditya K.; Indrayani, Ervina; Hanum, Laila
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Publisher : Jurnal Biologi Papua

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Abstract

Venomous snakebite is an important cause of morbidity and mortality, and is one of the major health problems in many regions of the world. Medicinal Plant which are effectively inhibitor and neutralize the snake venom and it is considered as a valuable source of natural products for development of medicines against venomous snake bite. The biomedical value of these natural inhibitors can lead to the development of new therapeutics for an assortment of diseases as well as contributing to efficient antivenoms for the treatment of ophidic accidents.Key words: pathophysiology, snake bite, envenomation, medicinal plant, therapeutic
CHARACTERISTICS OF HABITAT, DISTRIBUTION, AND DIVERSITY OF ANOPHELES SPP IN KEMELAK BINDUNG LANGIT VILLAGE, OGAN KOMERING ULU REGENCY, SOUTH SUMATRA Maretasari, Giri; Windusari, Yuanita; Lamin, Syafrina; Hanum, Laila; Septiawati, Dwi
Journal of Environmental Science and Sustainable Development Vol. 2 No. 2 (2019)
Publisher : UI Scholars Hub

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Abstract

Malaria is an infectious disease caused by Plasmodium andis transmitted through the bite of a female Anopheles vector. Ogan Komering Ulu (OKU) is a district in South Sumatra that is endemic to malaria. The study aims to determine habitat type, environmental factors that influence larvae development, and distribution of Anopheles larvae. The experiment was conducted from January to February 2019 in the Kelurahan Kemelak Bindung Langit, OKU. Species identification was carried out in the Entomology Laboratory, Baturaja Health Research and Development Center, OKU. Sampling locations were determined based on field observations, through simple purposive sampling. Identification of mosquito larvae which were maintained in the laboratory, showed that they originated from four Anopheles species namely An. vagus, An. barbirostris, An. kochi, and male Anopheles. The dominant habitat (76,89%) was rice fields. The characteristics of larval breeding habitats included water pH of 5-6, water temperature of 280C-320C, light intensity of 756 - 761 mmHg, visual clear water, muddy substrates, and habitat distance with houses of 10 -60 m. The Anopheles type diversity index (H ') was low (0.04-0.36). The larval density was the highest in RT 1 and RT 2 (as many as 2.5 larvae/cauldrons), and the lowest in RW 3 locations (as many as 0.1 larvae/cauldron), which had the same habitat type, namely, rice fields. The highest dominance index (C) was found in male Anopheles (C = 1), and the lowest was detected in An. kochi (C = 0.02) and An. barbirostris (C = 0.01). The pattern of the spread of Anopheles based on the Morishita index was grouped (Id> 1) and uniform (Id <1).
Genetic Relatedness among Duku, Kokosan, and Pisitan in Indonesia Based on Random Amplified Polymorphic DNA Markers Hanum, Laila; Kasiamdari, Rina Sri; ., Santosa; ., Rugayah
Indonesian Journal of Biotechnology Vol 17, No 2 (2012)
Publisher : Universitas Gadjah Mada

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Abstract

Genetic relatedness among duku, kokosan, and pisitan from Indonesia were investigated using random amplified polymorphic DNA (RAPD) markers. Eleven primers (OPA-01, OPA-02, OPA-10, OPB-07, OPB-11, OPB-12, OPB-15, OPT-16, OPU-14, OPU-19, and OPU-20) were used for amplification and yielded a total of 174 DNA bands, of which 167 were polymorphic. Primer OPA-10, OPB-11, OPB-12, OPB-15, and OPU-19 produced all of the polymorphic DNA bands. The size of the amplified DNA fragments ranged from 41-1546 bp. The dendrogram separated into two clusters at a genetic similarity coefficient of 0.76. The cluster 1 consisted of subclusters duku and several pisitan (pisitan OKI, pisitan Sleman, pisitan Hatu, pisitan Punggur, and pisitan Tanjung), and cluster 2 consisted of subclusters kokosan and pisitan. In the kokosan subclusters, including duku Drendan. Dendrogram supported the determination of taxonomic status of duku, kokosan, and pisitan as one species, namely Lansium domesticum Corr. and its divided into two groups, namely L. domesticum &rsquo;duku group&rsquo; and L. domesticum &rsquo;pisitan-kokosan group&rsquo;. Thus, RAPD analysis was useful tool for determining the genetic variation and the genetics relatedness among duku, kokosan, and pisitan in Indonesia.Key words: duku, kokosan, pisitan/langsat, genetic relatedness, RAPD
The Phylogenetic Relationship Among Varieties of Lansium domesticum Correa Based on ITS rDNA Sequences Hanum, Laila; Kasiamdari, Rina Sri; ., Santosa; ., Rugayah
Indonesian Journal of Biotechnology Vol 18, No 2 (2013)
Publisher : Universitas Gadjah Mada

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Abstract

Lansium domesticum Corr. with vernacular name in Indonesian duku has been reported containingtherapeutic bioactive compounds, and some of these compounds shown to be potent antitumor, anticancer,antimalaria, antimelanogenesis, antibacteria, and antimutagenic activities. This plant is commonly known asduku, kokosan and langsat by the local community in Indonesia. The morphological appearance of all varieties isnearly the same, and identifi cation of the varieties is very diffi cult for growers. Variation of DNA sequences ofthe ITS (Internal transcribed spacer) region can be used as a molecular character to determine the phylogeneticrelationship of different varieties of L. domesticum. The aims of this study were to determine taxonomy status ofduku, kokosan, and langsat, also phylogenetic relationship among varieties of L. domesticum based on ITS rDNAsequencing. DNA was isolated from leaves of plant and then amplifi ed using F1 and R1 primers. Nucleotidesequences were identifi ed using Sequence Scanner Software Programm version 1.0, nucleotide sequences from18S, ITS1, 5.8S, ITS2 and 26S region, that has been mergered using EditSeq and SegMan in software Suite forSequence Analysis DNASTAR Lasergene DM version 3.0.25. The results of study showed that DNA fragmentsranging in size from 782-810 bp. Different pattern of DNA fragments indicated polymorphism among duku,kokosan, and langsat. Based on the results of the ITS rDNA sequencing and phylogenetic tree analysis. Itwas determined that Lansium and Aglaia are a separated genus with the similarity index value of 0.98. Duku,kokosan and langsat were divided into two cluster, namely cluster kokosan-langsat and cluster duku with thesimilarity index value of 0.996.Keywords : Phylogenetic relationship, ITS region, L. domesticum, duku, kokosan, langsat
Analisis Polimorfisme Padi Varietas Lokal Sumatera Selatan Berdasarkan Pendekatan PCR-RAPD Adriansyah, Fikri; Hanum, Laila; Muharni, Muharni; Windusari, Yuanita
Jurnal Lahan Suboptimal : Journal of Suboptimal Lands Vol 7, No 1 (2018): JLSO
Publisher : Pusat Unggulan Riset Pengembangan Lahan Suboptimal (PUR-PLSO) Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (602.039 KB) | DOI: 10.33230/JLSO.7.1.2018.347

Abstract

Adriansyah et al, 2018. Polymorphism Analysis of Local Varieties of South Sumatra Rice Based on PCR-RAPD. JLSO 7(1):50-58.The existence of rice germplasm is threatened because of the introduction of various high-yielding varieties. This study aimed to analyze rice kinship and conservation of local varieties of South Sumatra rice. This study was conducted in August 2015 to December 2015. DNA isolation using the Promega Wizard Purification Systems KIT. This study uses OPA-9 primer, OPA-10, OPA-13, OPA-16. All primers can amplify DNA with optimal quality. OPA-9 primers produced 5 DNA bands, OPA-10 primers produced 9 DNA bands, OPA-13 primers produced 12 DNA and Primary OPA-16 bands producing 9 ppita DNA.
Analysis and Identification of Landuse on The East Coast of South Sumatera Using GIS Windusari, Yuanita; Hanum, Laila; Lestari, Margareta Sri
Proceeding of the Electrical Engineering Computer Science and Informatics Vol 2: EECSI 2015
Publisher : IAES Indonesia Section

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/eecsi.2.567

Abstract

Analysis and identification of land use in coastal areas to study the coastal environment Sembilang National Park in South Sumatra using remote sensing system (Geoinformation System) has been conducted from June until November 2014. The objective to study the changes that occur in the coastal environment as well as to identify and estimate the area use change existing mangrove areas in Region I of the Section of Sembilang National Park Management, South Sumatra. Methods for the analysis and identification based on Landsat image data 8 in 2013 using ENVI 4.3 and Arc GIS 9.3 software as well as the conversion of ground check. The results showed the use of land in the mangrove areas in the region I of the Section of Sembilang National Park Management classified into 5 classes, namely mangrove, water area, mangrove shrubs, mainland mud, and ponds areas. The area of each class were observed in sequence as follows 8921.19 ha (41.69%) is a mangrove area; 3934.3 ha (23.28%) is water areas; 3.608,52ha (17.41%) is an area of mangrove shrubs; 1.649,11ha (9.05%) is mainland mud and settlement area; and 1.561,04ha (8.57%) is the ponds areas. The percentage of the class obtained as a result of the conversion of ground check is based on the land use map data with the total area observed.
Patofisiologi Bisa Ular dan Aplikasi Terapi Tumbuhan Obat Antiophidia (Antibisa) Karim, Aditya K.; Indrayani, Ervina; Hanum, Laila
JURNAL BIOLOGI PAPUA Vol 6, No 2 (2014)
Publisher : JURNAL BIOLOGI PAPUA

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Abstract

Venomous snakebite is an important cause of morbidity and mortality, and is one of the major health problems in many regions of the world. Medicinal Plant which are effectively inhibitor and neutralize the snake venom and it is considered as a valuable source of natural products for development of medicines against venomous snake bite. The biomedical value of these natural inhibitors can lead to the development of new therapeutics for an assortment of diseases as well as contributing to efficient antivenoms for the treatment of ophidic accidents. Key words: pathophysiology, snake bite, envenomation, medicinal plant, therapeutic.
Tumbuhan Duku: Senyawa Bioaktif, Aktivitas Farmaklogis dan Prospeknya dalam Bidang Kesehatan Hanum, Laila; Kasiamdari, Rina S.
JURNAL BIOLOGI PAPUA Vol 5, No 2 (2013)
Publisher : JURNAL BIOLOGI PAPUA

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Abstract

Lansium domesticum Corr. (Meliaceae) is the popular tropical plant producing economic edible fruits found mainly in Southeast Asia. Seed, leaf, bark, stalks and fruit skin extracts of this plant are potential sources for compounds with broad spectrum of pharmacological activities such as antitumor, anticancer, antimalaria, antimelanogenesis, antibacteria and it may lead to the discovery of a new compouds used for antimutagenic and antioxidative stress. Bioactive compounds, pharmacological activities and prospect this plant in medical application will be discussed in this paper. Key words: Lansium domesticum, bioactive compounds, pharmacological activities, medical application.
Analysis of Vegetation in Green Open Space of Gasing Industrial Area Oktaviani, Siti Indah; Hanum, Laila; Negara, Zaidan P
Science and Technology Indonesia Vol 3 No 2 (2018): April
Publisher : ARTS Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (684.155 KB) | DOI: 10.26554/sti.2018.3.2.81-88

Abstract

The study aims to determine the diversity of vegetation in the Green Open Space of the Gasing Industrial Area. The study was conducted from April to July 2017. The method of analysis used quadratic method with 2 plots at different location with three repetitions, quantitative data analysis was done on density value, dominance, frequency, important value and diversity index of each plant species. The results showed that vegetation consists of 16 tribes and 19 species, dominated by Pteridophyta and Spermatophyta. Value of vegetation diversity (2,24) and uniformity value 0,30. The higher number of the species, the higher diversity index of the species. Such characteristics are caused by environmental influences such as organic matter content and low pH and factors derived from human intervention. Keywords: Vegetation, Diversity, industrial area