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All Journal International Journal of Electrical and Computer Engineering (IJECE) Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Jurnal Fitopatologi Indonesia Jurnal Teknologi Dan Industri Pangan Jurnal Ilmu dan Teknologi Kelautan Tropis Jurnal Sain Veteriner Indonesian Journal of Electronics and Instrumentation Systems Indonesian Journal on Computer and Cybernetics Systems Jurnal Informatika JURNAL PANGAN DAN GIZI Jurnal Pendidikan Matematika Media Informatika Seminar Nasional Aplikasi Teknologi Informasi (SNATI) Jurnal Bahtera - Jurnal Pendidikan Bahasa dan Sastra Indonesia Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Ilmu Komputer Jurnal Veteriner MEDIA KESEHATAN MASYARAKAT INDONESIA Jurnal Psikologi Agrikultura UG Journal Jurnal Ilmiah pesona PAUD Bioscience Jurnal ILMU DASAR Journal of Business and Management Jurnal Program Magister Ilmu Sosial Universitas Tanjungpura Jurnal Pendidikan dan Pembelajaran Jurnal Kedokteran Hewan Jurnal INKOM Empati Jurnal Tanah Tropika Jurnal Gizi Klinik Indonesia Jurnal Psikologi Proceedings of KNASTIK Accounting TELKOMNIKA Telecommunication, Computing, Electronics and Control Humanitas: Indonesian Psychological Journal Jurnal Informatika Disease Prevention and Public Health Journal (DPPHJ) Cropsaver : Journal of Plant Protection Abdimas Dinamika Informatika Caraka Tani - Agriculture Science Journal Sains Tanah JUTI: Jurnal Ilmiah Teknologi Informasi Spektrum Hukum Jurnal Ilmiah Hukum dan Dinamika Masyarakat Explore: Jurnal Sistem Informasi dan Telematika (Telekomunikasi, Multimedia dan Informatika) Medical Journal of Indonesia Jurnal technoscientia Jurnal Teknologi Pendidikan Sejarah Jurnal Hortikultura Jurnal Penelitian Pascapanen Pertanian Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Indonesian Journal of Cancer Chemoprevention Telematika : Jurnal Informatika dan Teknologi Informasi Jurnal Ilmu-Ilmu Peternakan (Indonesian Journal of Animal Science) Nexus Biomedika WIDYATAMA Proceeding of the Electrical Engineering Computer Science and Informatics Dharmakarya AGRIVITA, Journal of Agricultural Science Pro Bisnis Jurnal Mamangan AGRICOLA Jurnal Agritech Majalah Kedokteran Gigi Indonesia Indonesian Journal of Biotechnology International conference on Information Technology and Business (ICITB) Buletin Psikologi Jurnal GAMAJOP Seminar Nasional Informatika (SEMNASIF) Jurnal Teknologi dan Sistem Informasi Jurnal Intervensi Psikologi (JIP) Jurnal Counsellia The Asian Journal of Technology Management (AJTM) Biopropal Industri SOSIOLOGI NUSANTARA Jurnal Perlindungan Tanaman Indonesia Gadjah Mada Journal of Psychology Jurnal Didascein Bahasa JTET (Jurnal Teknik Elektro Terapan) Sriwijaya Journal of Environment Jurnal Ilmiah Mahasiswa Fakultas Keperawatan Jurnal Manajemen Pendidikan JURNAL AGRILAND Jurnal Ilmiah Teknosains Jurnal Ilmu Pangan dan Hasil Pertanian Pro Food AGRISAINTIFIKA Jurnal Ilmu-ilmu Pertanian Jurnal Ecopsy Jurnal Obsesi : Jurnal Pendidikan Anak Usia Dini JIKO (Jurnal Informatika dan Komputer) JRPM (Jurnal Review Pembelajaran Matematika) English Community Journal Jurnal Keperawatan Padjadjaran SAINS TANAH - Journal of Soil Science and Agroclimatology Agrosains: Jurnal Penelitian Agronomi Caraka Tani: Journal of Sustainable Agriculture MUST: Journal of Mathematics Education, Science and Technology Jurnal Gizi Klinik Indonesia Jurnal Mitra Manajemen Jurnal TAM (Technology Acceptance Model) INOVTEK Polbeng - Seri Informatika JURNAL BAHASA, SASTRA DAN PEMBELAJARANNYA PEDAGOGI Jurnal Kimia Terapan Indonesia Indonesian Journal of Chemistry ANNALES BOGORIENSES Jusikom : Jurnal Sistem Komputer Musirawas Jurnal Mikologi Indonesia Jurnal Perikanan Universitas Gadjah Mada Jurnal SainHealth Diksa JURNAL TEKNIK INFORMATIKA DAN SISTEM INFORMASI ADMINISTRASI PUBLIK Jurnal Agrotek Tropika Jurnal Sinergitas PKM & CSR Jurnal BIOEDUIN : Program Studi Pendidikan Biologi Jurnal PEMBAHSI (PEMBELAJARAN BAHASA DAN SASTRA INDONESIA) JUTIM (Jurnal Teknik Informatika Musirawas) Jiko (Jurnal Informatika dan komputer) Cakrawala Dini: Jurnal Pendidikan Anak Usia Dini Jurnal ACSY : Jurnal Accounting Politeknik Sekayu Comm-Edu (Community Education Journal) JURNAL PENDIDIKAN TAMBUSAI Ulumul Syar'i IJID (International Journal on Informatics for Development) Ensiklopedia of Journal Islamic Guidance and Counseling Journal Andragogi: Jurnal Diklat Teknis Pendidikan dan Keagamaan IJISCS (International Journal Of Information System and Computer Science) Teknologi Indonesia JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Ilmiah Inovasi Jurnal SPATIAL Wahana Komunikasi dan Informasi Geografi JURNAL SAINTIS Menara Ilmu EARLY CHILDHOOD : JURNAL PENDIDIKAN Jurnal Intake : Jurnal Penelitian Ilmu Teknik dan Terapan Soil REns AL MUNIR : Jurnal Komunikasi dan Penyiaran Islam Agrotechnology Research Journal TRANSFORMASI: Jurnal Manajemen Pemerintahan Cendekiawan bit-Tech Pengembangan Sektor Kelautan, Perikanan, Dan Pemberdayaan Masyarakat Pesisir Untuk Meningkatkan Pendapatan Asli Daerah Menuju Jawa Tengah Yang Maju, Mandiri, Dan Sejahtera PRIMA: Journal of Community Empowering and Services Genta Mulia : Jurnal Ilmiah Pendidikan Bina Gogik: Jurnal Ilmiah Pendidikan Guru Sekolah Dasar Respati Indonesian Journal of Electrical Engineering and Computer Science Jurnal Keperawatan 'Aisyiyah Jurnal Ilmu ilmu Pertanian NANAEKE International Journal of Advance Tropical Food (IJATF) JURNAL TEKNOLOGI TECHNOSCIENTIA Edudikara: Jurnal Pendidikan dan Pembelajaran Tunas Medika Jurnal Kedokteran & Kesehatan
Articles

An Application of Expert System to Identify Trees Utilizing Leaf Images Sarita, Muhammad lhsan; Hartati, Sri
IJCCS (Indonesian Journal of Computing and Cybernetics Systems) Vol 1, No 2 (2007): July
Publisher : IndoCEISS in colaboration with Universitas Gadjah Mada, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2439.881 KB) | DOI: 10.22146/ijccs.2275

Abstract

AbstractTree identification is a very important to support almost all activities in the forest sector. Unfortunately, the inavailability of data and computer programs that is user friendly have caused ineficiency in tree identification. This research tries to make an expert system to identify trees by using the leaf images. To store the data in the knowledge base one must choose one of the some leaf images that are in the data base available in the program according the characteristic of the leaf. Each leaf image has a code and the accumulation of all codes build a tree code then this code is saved in the knowledge base. The tree code is used to identify a tree by making the comparison between input chosen by user and the tree code in the knowledge base using forward chaining. User who has information about a tree can add to the knowledge base but this information must be validated by an expert before it is used in the system. Another task of an expert is to give a CF (certainty factor) for each tree.The result of this research shows that no more errors are found due to input mistakes and the program is more user friendly. Another advantage is that the knowledge base is more flexible, dynamic and well organized Validation of knowledge base by experts can increase the quality and accuracy of using the knowledge base system.Keywords : expert system, leaf image, knowledge base, forward chaining, CF
An Application of Expert System For Diagnozing Endoparsitism Gastrointestinal Disease In Livestock Animals Efendi, Rusdi; Hartati, Sri
IJCCS (Indonesian Journal of Computing and Cybernetics Systems) Vol 1, No 2 (2007): July
Publisher : IndoCEISS in colaboration with Universitas Gadjah Mada, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3100.659 KB) | DOI: 10.22146/ijccs.2276

Abstract

AbstractThe goal of this research is to make an expert system as a tool for diagnozing endoparsitism gastrointestinal disease for cows and sheep. The knowledge base of the system has been acquired from some interviews with some doctors from the internal diseases animal's unit at Animal's Hospital, Gadjah Mada University Jogjakarta, some text books, journals, and research papers. The inference machine of the system uses Forward Chaining and uncertainty data methods using Dempster-Shafer Theory.The system has a consultation session with an interactive dialog that can be used by the users. A user gives information such as user's data, and answers the questions about the endoparsitism gastrointestinal symptoms that might be had by his animal. From the answers, the system computes the possibility of the animal to suffer from endoparsitism gastrointestinal, informs the life cycle parasites, and suggests a therapy for it.Keywords : Expert System, diagnoze, endoparsitism gastrointestinal disease, Forward chaining method, Dempster-Shafer Teary
Klasifikasi Data Microarray Menggunakan Discrete Wavelet Transform dan Extreme Learning Machine Khadijah, Khadijah; Hartati, Sri
IJCCS (Indonesian Journal of Computing and Cybernetics Systems) Vol 9, No 1 (2015): January
Publisher : IndoCEISS in colaboration with Universitas Gadjah Mada, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (714.522 KB) | DOI: 10.22146/ijccs.6638

Abstract

AbstrakData microarray digunakan sebagai alternatif untuk diagnosa penyakit kanker karena kesulitan dalam dignosa kanker berdasarkan bentuk morfologis, yaitu perbedaan morfologis yang tipis antar jenis kanker yang berbeda. Penelitian ini bertujuan untuk membangun pengklasifikasi data microarray. Proses klasifikasi diawali dengan reduksi dimensi data microarray menggunakan DWT, dengan cara mendekomposisi sampel hingga level tertentu, kemudian mengambil nilai koefisien aproksimasi pada level tersebut sebagai fitur sampel. Fitur tersebut selanjutnya menjadi masukan untuk klasifikasi. Metode klasifikasi yang digunakan adalah ELM yang diterapkan pada RBFN. Dataset yang digunakan adalah data microarray multikelas, yaitu dataset GCM (16.063 gen, 14 kelas) dan Subtypes-Leukemia (12.600 gen, 7 kelas).Pengujian dilakukan dengan cara membagi data latih dan data uji secara random sepuluh kali dengan proporsi data yang sama. Classifier yang dihasilkan dari penelitian ini untuk dataset GCM belum memiliki performa yang cukup baik, ditunjukkan dengan nilai akurasi sekitar 75% ± 6,25% dan nilai minimum sensitivity yang masih rendah, yaitu 15% ± 19,95% menunjukkan bahwa sensitivity untuk tiap kelas belum merata, terdapat beberapa kelas yang sensitivity-nya masih rendah. Namun, classifier untuk dataset Subtypes-Leukemia yang memiliki jumlah kelas lebih sedikit dari dataset GCM memiliki performa yang cukup baik, ditunjukkan dengan nilai akurasi 87,68% ± 2,88% dan minimum sensitivity 51,90% ± 20,29%.   Kata kunci— microarray, ekspresi gen, DWT, ELM, RBFN AbstractMicroarray data is used as an alternative in cancer diagnosis because of the difficulties cancer diagnosis based on morphologis structures. Different classes of cancer usually have poor distintion of morphologis structures. The aim of this reserach is to bulid microarray data classfier. The classification process is started by reducing dimension of microarray data. The method used to reduce the microarray data dimension is DWT by decomposing the samples until certain decomposition level and then use approximation coefficients at those level as feature to classifier. Classifier used in this reserach is ELM implemeted on RBFN. Dataset used are GCM (16.063 genes, 14 classes) and Subtypes-Leukemia (12.600 genes, 7 classes). Testing process is done by randomly dividing the training and testing data ten times with same proprotion of training and testing data. The perfomance of classifier built in this research is not so good for GCM dataset, shown by accuracy 75% ± 6,25% and mean of minimum sensitivity 15% ± 19,95%. The low minimum sensitivity indicate that there are few classes that have low sensitivity. But the classifier for Subtypes-Leukemia dataset give better result, that is accuracy 87,68% ± 2,88%  and mean of minimum sensitivity 51,90% ± 20,29%.    Keywords— microarray, gene expression, DWT, ELM, RBFN
Karakterisasi Anggrek Alam secara Morfologi dalam Rangka Pelestarian Plasma Nutfah Hartati, Sri; Darsana, Linayanti
Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Vol. 43 No. 2 (2015): Jurnal Agronomi Indonesia
Publisher : Indonesia Society of Agronomy (PERAGI) and Department of Agronomy and Horticulture, Faculty of Agriculture, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (463.366 KB) | DOI: 10.24831/jai.v43i2.10419

Abstract

ABSTRACTMorphological characters of natural orchids (species) is an important key for successful breeding program of orchids. This study was aimed to determine the morphological diversity and to study the genetic relationship among natural orchids from Java. The characterization was conducted on 12 orchids collected from Central, East and West Java from April to September 2012. Twenty five characters including stem, leaves, flower, pseudobulb, and root type were evaluated and scored based on Guidance of Orchid Characterization. Cluster analysis was done using the NTSYSpc version 2.02i under UPGMA function of SimQual. The study showed that there was a diversity on morphology of stem, pseudo bulb, leaf, flower and root type. Dendrogram based on genetic similarity at 52% clustered the population into two groups. The first group consisted of Paphiopedilum purpurascens, P. javanicum, P. glaucophylum, Coelogyne flexuosa, C. spesiosa, Dendrobium mutabile. Bulbophyllum blumei and B. biflorum. The second group was Coelogyne tomentosa, C. trinervis, D. crumenatum, and B. flavescens LindlKeywords: cluster analysis, dendrogram, diversity, morphology
PENGARUH PERMAINAN DORE TERHADAP KEMAMPUAN BERBICARA ANAK DI TAMAN KANAK-KANAK DHARMA WANITA UNIVERSITAS NEGERI PADANG Gusmeta, Gusmeta; Muryanti, Elise; Hartati, Sri
Jurnal Ilmiah Pesona PAUD Vol 4, No 1 (2015)
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (411.975 KB)

Abstract

Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh Permainan Dore terhadap kemampuan berbicara anak di Taman Kanak-Kanak  Dharma Wanita Universitas Negeri Padang. Jenis penelitian yang digunakan adalah metode kuantitatif dengan jenis eksperimen atau penelitian quasy experimental (eksperimen semu) dengan menggunakan Permainan Dore. Berdasarkan hasil analisis data, diperoleh nilai rata-rata hasil kemampuan berbicara anak di kelas eksperimen yang menggunakan Permainan Dore lebih tinggi (86,2)  dibandingkan kelas kontrol yang menggunakan Permainan Kotak Pos (66,4). Berdasarkan perhitungan t-test diperoleh bahwa t hitung lebih besar dari t tabel menunjukkan bahwa terdapat pengaruh yang signifikan terhadap kemampuan berbicara anak. Dengan demikian disimpulkan bahwa dengan menggunakan Permainan Dore sangat berpengaruh terhadap kemampuan berbicara anak di Taman Kanak-kanak Dharma Wanita Universitas Negeri Padang. 
IMPROVEMENT OF PHOSPHATE FERTILIZATION METHOD IN WETLAND RICE Cahyono, Ongko; Hartati, Sri
AGRIVITA, Journal of Agricultural Science Vol 35, No 1 (2013)
Publisher : Faculty of Agriculture University of Brawijaya in collaboration with PERAGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17503/agrivita.v35i1.114

Abstract

The low efficiency of Phosphate fertilization on wetland rice may be overcame by using quickly dissolve P fertilizer. However, for soils containing high dissolve Fe, such as Alfisol and Oxisol, will induce the formation of Fe-P bonding. Therefore, to use the quickly dissolve P fertilizer  in such soils should be done by split application. The research aimed to assess better P fertilization method for wetland rice which used quickly dissolve P fertilizer given in split application. The research concluded that the application of quickly dissolve P fertilizer to Alfisol and Oxisol which was applied in split application by twice (0 and 30 days after planting) and three times (0, 15 and 30 days after planting) increased the eficiency of P fertilization in wetland rice.  The split application of 75 kgs perhectare (one half of recommended dose) in Alfisol yielded dry seed as high as 6,374 kgs per hectare (at the twice application), 6,280 kgs per hectare (the three times application)c while the control treatment yielded as high as 6,027 kgs per hectare.  In Oxisol the yield of rice was 8,200 kgs per hectare fo the control treatment, 8,027 kgs per hectare for the twice application and 8,440 kgs per hectare for the three time applications.
Komposisi Komunitas Serangga Aphidophaga dan Coccidophaga pada Agroekosistem Kacang Panjang (Vigna sinensis l.) di Kabupaten Garut Puspasari, Lindung Tri; Sianipar, Martua Suhunan; Hartati, Sri
Agrikultura Vol 27, No 1 (2016): April, 2016
Publisher : Fakultas Pertanian Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (346.077 KB) | DOI: 10.24198/agrikultura.v27i1.8474

Abstract

ABSTRACTComposition of Aphidophaga and Coccidophaga Insect Communities on Long Bean Agroecosystem (Vigna sismensis L.) at Garut RegencyThe research about Aphidophaga and Coccidophaga insect composition comunity on long beans (Vigna sinensis L.) agroecosystems was done in the month of April to November 2011 in Haruman Village, Leles District, Garut Regency. Research was conducted in the form of surveys which were done by collecting insects directly and using various traps ie yellow traps board, fitfall traps, and nets swinging. The dominant insect pest that found was Aphis craccivora which causing percentage of damage to the plants ranging from 20% to 90%. Types of aphidophaga and coccidophaga found were belong to the Order of Coleoptera : Family Coccinellidae Menochilus sexmaculatus, Micraspis sp., Harmonia sp., Verania lineata, Curinus coeruleus, Scymnus sp., Coccinella transversalis); the Order of Diptera : Family Syrphidae namely Ischiodon scutellaris; Neuroptera: Family Hemerobiidae; the Order of Diptera : Family Cecidomyiidae Aphidoletes aphidimyza; and there was also Carabidae beetles of the Order Coleoptera with species diversity index wasl relatively low. The highest abundance of predators of coccidophaga and aphidophaga group was dominated by Ischiodon scutellaris and Menochilus sexmaculatus.Key words: Diversity, Abundance, Dominant species, Insect pestsABSTRAKPenelitian mengenai komposisi komunitas serangga aphidophaga dan coccidophaga pada Agroekosistem kacang panjang (Vigna sinensis (L.) telah dilaksanakan pada Bulan April–November 2011 di Desa Haruman Kecamatan Leles Kabupaten Garut. Penelitian dilakukan menggunakan metode survei dengan mengoleksi serangga secara langsung, dan menggunakan berbagai perangkap antara lain perangkap papan kuning, fitfall trap, dan jaring ayun. Serangga hama dominan yang ditemukan adalah Aphis craccivora dengan persentase serangan berkisar 20% - 90%. Jenis aphidophaga dan coccidophaga lain yang ditemukan yaitu dari Ordo Coleoptera : Famili Coccinellidae: Menochilus sexmaculatus, Micraspis sp., Harmonia sp., Verania lineata, Curinus coeruleus, Scymnus sp., Coccinella transversalis; Ordo Diptera : Famili Syrphidae yaitu Ischiodon scutellaris; Neuroptera : Famili Hemerobiidae; Ordo Diptera : Famili Cecidomyiidae Aphidoletes aphidimyza; serta terdapat pula kumbang Carabidae dari Ordo Coleoptera dengan indeks keragaman spesies yang masih tergolong rendah. Kelimpahan tertinggi predator dari kelompok aphidophaga dan coccidophaga didominasi oleh spesies Ischiodon scutellaris dan Menochilus sexmaculatus.Kata kunci : Keragaman, Kelimpahan, Spesies dominan, Serangga hama
PELAKSANAAN STANDAR OPERASIONAL PROSEDUR DI TAMAN PENITIPAN ANAK HIKARI KIDS CLUB PADANG Delly, Surya; Zulminiarti, Zulminiarti; Hartati, Sri
Jurnal Ilmiah Pesona PAUD Vol 5, No 2 (2018)
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (834.716 KB)

Abstract

Penelitian bertujuan untuk mengetahui pelaksanaan standar operasional prosedur di Taman Penitipan Anak Hikari Club Padang. Pengasuh tidak menjalankan kegiatan pembelajaran sesuai dengan Standar Operasional Prosedur yang telah dibuat. Melalui penelitian ini peneliti ingin melihat bagaimana pelaksanaan standar operasional prosedur di Taman Penitipan Hikari Club Padang. penelitian ini menggunakan jenis penelitian deskriptif kualitatif. Dengan Setting Penelitian dilakukan di Taman Penitipan Anak (TPA) Hikari Club Padang anak usia 0-6 tahun. Penelitian ini bersumber dari subyek penelitian dengan purposive sampling (sampel bertujua) dan informasi penelitian. Teknik Pengumpulan data menggunakan teknik observasi, teknik wawancara, dan teknik dokumentasi. Hasil penelitian menunjukkan bahwa Standar operasional prosedur sterilisasi botol susu yang dilaksanakan di Taman Penitipan Anak Hikari pada terlihat hanya pada usia 3 tahun saja yang melaksanakannya sedangkan untuk Standar operasional prosedur makan siang, saat bayi/anak tidur siang, toilet training, dan pelayanan kesehatan semua umur melaksanakannya dengan baik. 
PENGARUH MEDIA SANDPAPER LETTER TERHADAP KEMAMPUAN MENGENAL HURUF ANAK DI TK ISLAM BUDI MULIA PADANG Rahmadani, Fita; Suryana, Dadan; Hartati, Sri
Jurnal Ilmiah Pesona PAUD Vol 6, No 1 (2019)
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (770.373 KB)

Abstract

Pengetahuan tentang huruf bagi anak bagi anak 4-5 tahun sangat penting untuk proses membaca  dan menulis. Untuk merealisasikan pembelajaran mengenal huruf di perlukan media yang sesuai dengan karakteristik perkembangan anak .Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan media Sandpaper letter  terhadap kemampuan mengenal huruf anak usia 4-5 tahun. Metode penelitian yang digunakan adalah kuantitatif yang berbentuk quasi eksperimen. Berdasarkan analisis data di peroleh hasil penelitian yang dilakukan di Taman Kanak-kanak Islam Budi Mulia Padang dengan rata-rata hasil kemampuan mengenal huruf anak kelas eksperimen (A1) yang dilakukan dengan media sandpaper letter lebih tinggi dibandingkan anak di kelas kontrol (A2) yang dilakukan dengan media kartu huruf yaitu 78,25 kelas eksperimen dan dikelas kontrol adalah 71,25. Dengan demikian media sandpaper letter terbukti berpengaruh terhadap kemampuan membaca anak di Taman Kanak-kanak Islam Budi Mulia Padang. Dimana pada kelas eksperimen anak dapat mencapai nilai tertingginya yaitu 93,75 dan sedangkan di kelas control nilai tertinggi anak hanya mencapai 81,25.
Antiviral Effect of Pterocarpus indicus Willd Leaves Extract Against Replication of Dengue Virus (DENV) In Vitro Dewi, Beti Ernawati; Angelina, Marissa; meilawati, lia; Hartati, Sri; Dewijanti, Indah Dwiatmi; Santi, Mei Ria; Desti, Hidayati; Sudiro, Mirawati
Journal of Tropical Life Science Vol 8, No 1 (2018)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (886.48 KB) | DOI: 10.11594/jtls.08.01.10

Abstract

Dengue hemorrhagic fever (DHF) is major public health problem in tropical and subtropical areas of the world with lack of approved vaccines and effective antiviral therapies. With no current treatment for illness attributed to dengue virus (DENV) infection other than supportive care, therapeutic strategies that use natural extract was developed. Indonesia have many plants that potential for antiviral drµgs such as Pterocarpus indicus Willd (P. indicus). The objective of this study was to determine the effect of P. indicus to inhibit DENV replication. We used a well-differentiated hepatocytes-derived cellular carcinoma cell line (Huh-7 it-1 cells) to determine and select antiviral activity. The toxicity effects were determined by MTT assay. Then, the suppression of DENV replication was determined by Focus assay. Dengue infected cells with DMSO were used as control. We found that crude extract (Pi), hexane (Pi.1) and ethyl acetate (Pi.2) extract showed strong inhibition with high selectivity index (SI) of 1,392; 285.36 and 168.56 respectively.  Sub fraction of Pi.1 and Pi.2 still showed strong inhibition with high SI.  Further sub-sub fraction of Pi.2 such as Pi.2.12 and Pi.2.12.1 still showed inhibition of DENV replication but there was reduction of SI value. The mechanism experiment of Pi.2.12, we found that Pi 2.12 more profound to inhibit in the post infection stage that entry or pre-infection. We conclude that the sub-fraction of Pi.2.12 has potential antiviral activity against DV infection in vitro. Further studies are still needed to investigate the pure compound of Pi.2.12 that inhibit and have advantages in the future as alternative for treatment of DENV infection.
Co-Authors ', M. Nababan ', Ramadi 'Uyun, Shofwatul . Kosasih . Megawati . Pujianto . Solikhah . Suryono . Triyem ., Andriyani ., Octaviani A. Intan Niken Tari A.Intan Niken Tari Abdiansah Abdiansah Abdul Malik Ashari, Abdul Malik Abdurrakhman WKA Achmad Mujab Masykur Addarsy, Rahmatika ADE ANDRIANI Ade Muhammad Adi Nugroho Aditha Fajrina Afandi, Ardian Rahman Afrimasari, Eka Afriyanti Afriyanti, Afriyanti Ageng Suseno Agfianto Eko Putra Agus Budiyono, Agus Agus Harjoko Agus Limbang Wardani, Agus Limbang Agus Wartapa, Agus Agustinus Yogy Dwicahyo Nugroho Ahmad Yunus, Ahmad Ahnanto, Ahnanto Aina Musdholifah Alfarisa Nururrozi, Alfarisa Almar Aminudin, Almar Ana Setyowati Andriyani Puspitaningrum Anik Isnaeni Anita Listiara Aoki, Chie Aoki-Utsubo, Chie Apindis, Gennes Arlin Mela C. Apriyanto, Dadan Ramadhan Ardiah Juita Ardiyansah, Bayu Rian Aridhanyati Arifin Aris Budianto, Aris Ariwibowo, Krisdyanto Arwani, Muhaammad Marwan Arwani, Muhammad Marwan Asmarani Kusumawati Asmoro, Novian Wely Asmoro, Novian Wely Asmoro, Novian Wely Assalam, Sohib Atiek Soemiati Atik Ratnawati Ayu Rahning Putri, Luh Arida Azhari Azhari Azhari Subanar Aziz Q, Ikhwan B.S.Kardono, Leonardus Bambang Sugiantoro Bambang Sumiarto Bernard Renaldy Suteja BETI ERNAWATI DEWI Bina Kurniawan Brian Shendy Haryanto Budi Hariono Catur Budi Handayani Catur Gunawan Podo Winarno Ceppy Nasahi Cornelia Anggun Septria Costrie Ganes Widayanti Dadan Suryana, Dadan Danang Lelono Danar Dono Dedik Budianta Defi Wulandari, Defi Delly, Surya Desi Wulandari, Desi Desti, Hidayati Dewanto Harjunowibowo DEWI, BETTY ERNAWATI DEWI, INDAH Dewi, Mia Sukma Dewi, Sri Rosmala Dewi, Vira Kusuma Dewi, Vira Kusuma Dewijanti, Indah Dwiatmi Dewijanti, Indah Dwiatmi Dewijanti, Indah Dwiatmi Dian Ratna Sawitri Dian Veronika Sakti Kaloeti Dias Amartiwi Putri Gavinta, Dias Amartiwi Putri Diding HP Djemari Mardapi Drs. H. Irfan Akuntan Nursasmita. Dwi Irfianti, Asti Dwi Nur Prasetya Dwi Priyo Ariyanto Dwi Priyo Widodo, Dwi Dwi Priyowidodo Eka Ardhinie Eka Irmawati A Eka Wahyudi Ekawati -, Ekawati Eko Darmanto Elen Erniasita Elfira Rosa Pane Ema Utami Endah Yulia Endang S Rahayu Endang Yuniastuti Endro Yunianto Endy Paryanto Prawirohartono, Endy Paryanto Eni Harmayani Enny Itje Sela Enny Sudarmonowati Erick Alfons Lisangan, Erick Alfons Estalansa, Helna Estu Widodo, Estu Eva Latipah Fadly Azhar FAJAR NUGROHO Fani, Tian faujiah, chera rizqi Faujiyah, Chera Rizqi Fauzi, Rizky Fauzi, Rizky Fauzy Rachman Finta Amalinda Fitri Widiantini Fitria Roviqowati Fitriani, Maulida Ayu Friardi Ismed, Friardi Fudlel, Ahmad Yazid Ganapragasam, Angeline Gayatri Basuki Grece Novarizki Guntari Titik Mulyani Gusmeta, Gusmeta Hadiman, Hadiman Hadina, Fairuz Nurma HAK HOTTA Halimuddin, Halimuddin Hani Fitriani, Hani Haniati, Isna Luthfa Hanifa, Hanifa Hanum, Sri Handayani Hapsari, Ratna Cahyaning Harisna, Rubita Harto Widodo, Harto Hary Purnamaningsih Hastari Wuryastuti Hastari Wuryastuty Hastrini, Florentina Widi Hastuti, Desi Putri Hence Beedwel Lumentut, Hence Beedwel Hendra, Tomi Henricus E. A. Hendrata, Henricus E. A. Henricus EA Hendrata Henricus Roby Cahya Putra, Henricus Roby Cahya Heriyanto Heriyanto Hermansyah Hermansyah Herry Cahyana Hery Widijanto Heryumani JCP, Heryumani Hidayah, Husnul Himawati, Ika Pasca I Gede Aris Gunadi I Ketut Triyono I Usuman Ida Arlita Wulandari Ida Damayanti, Ida Ida Tjahajati Ihsani, Nurul Ilham Abdullah, Ilham Indah Dewiyanti, Indah Indahsari, Novy Indarjulianto, Sedarmanto Indra Indra Intan Niken Tari Intan Ratna Puri, Intan Ratna Irkham Widiyono Isnijah S.P., Siti Istikhomah Istikhomah, Istikhomah Ita Khairani IWO, IMACULATA Izhar Salim J.Sri Widada jamila Jamila Jani Kusanti Jati Ariati Jati Sasongko Wibowo Jauhari Syamsiah Jauhari Syamsiyah Jazi Eko Istiyanto Jiao, Yeo Suan Joannes Sri Widada Johan, Syafri Johansyah, Syafri Joko Prastowo Joko Winarno Julia, Dede Julius Hammer Juwari J, Juwari Kamiso H. N., Kamiso H. Kartika, Rosalina Anindia Sari Karuniawan, Dedy Khadijah Khadijah Khomsah, Nur Komariah Komariah Krisna Raharditia Kuneng Brojokusumo, Raden Dirgori KURNIA KURNIA, KURNIA Kurnianto, M Fatoni Kusrini Kusrini Kusumaningtyas, Amelia Ayu Kuswahyuning Kuswahyuning, Kuswahyuning Kusyairi, Umi Kuwat Triyana L., MEILYAWATI Larasati, Cindhe Putri Lasmono Tri Sunaryanto Lestari, Desti Tri Lestari, Desti Tri Lestari, Nora Agus Lia Meilawati Lilik Sumaryanti, Lilik Lina Handayani Linayanti Darsana Lindung Tri Puspasari Lintang Januardini, Lintang Liza Husnita Luciana Djaya, Luciana Lutfan Lazuardi M Hanafi M S Sinaga M. Hanafi Maba, Aprezo Pardodi Maimun Barmawi Maisyarah, Selly Mardiati Mardiati Maridjo Abdul Hasjmy, Maridjo Marissa Angelina Martin, Afrizal Martua Suhunan Sianipar, Martua Suhunan Masrukhan, Masrukhan Maulan Irwadi Mauliani, Annisa Megawati Megawati Meilani, Ayu Meity S Sinaga, Meity S Meity Suradji Sinaga Meri Erawati Meylina Diah Ekasari Michael Sihaloho Mirawati Sudiro Moh Luqman Shobrony, Moh Luqman Moh. Arief Bonis S Muhamad Muslihudin, Muhamad Muhammad Hanafi Muhammad Hanafiah Muhammad lhsan Sarita Muhammad Syaukani Muhammad Tasrif Mujiyo Mujiyo Mukodimah, Siti Mukodimah, Siti Mukodimah, Siti Mulud Suhardjo MULYADI, RAMA Munakhir Mudjosemedi Munakhir, Munakhir Murien Nugraheni Murinto Murinto Murinto, Muryanti, Elise Musthofa Musthofa Nafratilova Septiana, Nafratilova Nagari, Monica Pujian Nailul Fauziah Nanda, Adi Prasetia NANIK RAHMANI Ni Made Diska Widayani Nina Artanti Nita Etikawati Nofitri, Diana Noor Istifadah Nopianti, Heni Novi Ayu Kristiana Dewi, Novi Ayu Novilaressa, Putu Ghita Novita Novita Nugroho Susetya Putra Nunik Puji Lestari, Nunik Puji Nur Ismawati, Nur Nur Laili Nur Machfiroh Nur Pratiwi Noviati, Nur Pratiwi Nurhidayat Nurhidayat Nurhuda, Yeni Agus Nurlaily, Vivi Astuti Nururozi, Alfariza Nyimas Sa’diyah Octaviani Octaviani Ongko Cahyono Pardono Pardono Partomuan Simanjuntak Pradana, Rio Adi Pramono, Agung Budi Pramono, Doni Eko Hendro Praptosuwiryo, Titien Ng Prasetyaningtyas, Fitria Dwi Puastuti, Dwi Purnama Darmadji Purnama, Lia Sari Purnamawanti, Rena Purwaka, Purwaka Purwandari, Hesti Purwanto Purwanto Purwanto, Benito Purwanto, Benito Puspasari, Ervina Ryan Puspita Puji Rahayu, Puspita Puji PUTRA, DEDDI P PUTRA, HANIF ERONI Putra, Nugoho Susetyo Putra, Yan Putra, Yan Putri Pertiwi Rachman, Fauzy Rahayu Rahayu Rahmadani, Fita Rahman, Imas Kania Rahmawati, Dedah RAHMAWATI, DEDE Rakimahwati Rakimahwati, Rakimahwati Ramadi Ramadi, Ramadi Ratri Dewi Anggraini Retantyo Wardoyo Retno Rosariastuti Retno Widyastuti, Retno Retyanto Wardoyo, Retyanto Revita, Desi Reza Pulungan Riani Dwi Hastuti Ricky Wijaya RIKA MELIANSYAH Rindang Gunawati Rini Widayanti Rio Kurniawan Rita Wiryasaputra Rizkie, Lilian Rosihan Ariyuana, Rosihan Rosnita . Roy Silitonga Rugayah Rugayah Rukli Rukli Rusdi Efendi Rustiyarso . Ryan Anugerah Purwito, Ryan Anugerah S H Hidayat Saádah, Sumiyati Sahal, Ahmad Salahuddin Salahuddin Saleh Haji Salmin, Munazat Samekto Wibowo Sandi, Yongki Umam Sandi, Yongki Umam Santi, Mei Ria Santoso, Yuli saputri, lia Sari, Kenny Puspita Sari, Santika sari, santika Sartika, Ika Dewi Sartono Putro, Sartono Satria Abadi, Satria Setiawan, Mukhammad Andri Setiawan, Putra Aman Setio Budi, Nofiko Setiwan, Pika Setiwan, Pika Setyawan, Bayu Aji Sherly Jayanti Sholehah, Mar’atus Sidomulyo, MA Barokatul Qodiri SIska Rasiska, SIska Siswanti Siswanti Siti Istiqomah Siti Kurniawati Slamet Minardi Slamet Rahardjo Slamet Raharjo Slamet, Made Soedarmanto Indarjulianto Soedarmono, Pratiwi Soetanto, Hari Sri Andayani Sri Handayani SRI HENDRASTUTI HIDAYAT Sri Kusumadewi Sri Mulyana Sri Nurdiati Sri Pujiyati Sri Suwarno Sri Wahyuni Sri Widada Sri Yulianto J.P. Subahar, Subahar Subanar Subanar Subiantoro, Dadang Aris Sudadi Sudadi Sugiwinarsih S, Sugiwinarsih suhada, idad Suharno Suharno Sukaya, Sukaya Sulistyawati Sulistyawati Sumani Sumani Sumarno Sumarno Sumartono . Sumbari, Timotius A. Sumijati Sumijati Sunaryanto, Heri Suparjono Suparjono Suparmo . Supatmi Supatmi Supriyadi Supriyadi Supriyono Supriyono SURYO WIYONO Suwanto Raharjo Syahidah, Kholishotu Syahpirudin, Erry Tari, A. Intan Niken Tari, Agustina Intan Niken Tari, Agustina Intan Niken Tarina, Linda Tedy Rismawan Theresia Nadia Nugraheni Timorora Sandha Titis Kurniawan Tjala, Awaluddin Toto Sunarto Tri Puji Astuti Tri Untari Tri Wahyu Supardi Triyanto Triyanto Triyem, Triyem Triyono, Gandung Tyas Utami Umar Santoso Ummi Kaltsum VIDIAN, NAURA PRIMA Vrisca Amelia Suhardi Wae, Rahmawati Wahyu Daradjat Natawigena, Wahyu Daradjat Wahyu Kusumaningtyas Wardana, Ari Kusuma Waskita, Indra Purba Wawan Kurniawan Wayan Tunas Artama Wibowo, Adityo Permana Widodo Prijodiprodjo Widyatmani Sih Dewi Wijang Widhiarso Wijo Priyono Wilis, Andriyeni Nur Wirapratiwi, Dyah Kunti Wirman, Asdi WIRYOWIDAGDO, SUJASWADI Wisnu Nurcahyo Wiwik Hartatik Wiyono, S Woro Utari, Woro Woro Wulandari Yanuartono, Yanuartono Yanuartono, Yanuartono - Yeni Lestari Yeni, Afrita Yolanda Imelda Fransisca Tuapattinaya YOPI YOPI Yopi, nFN Yudi Anom Priambudi, Yudi Anom Yudi Pranoto Yudistira, Dwi Harya Yunior, Reynaldi Yuriadi Yuriadi, Yuriadi Yustinus Marsono Yusuf Hartono Yusuf, Mukhamad Agung Zainal Berlian Zakarias Situmorang, Zakarias Zid, Muhammad Zid Zulkardi Zulkardi Zulminiarti, Zulminiarti Zulminiati Zulminiati