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MOLECULAR PATHOGENESIS OF PREECLAMPSIA: MICRORNA HYPOTHESIS Andalas, Mohd.; Harapan, H.; Mudhakir, Diky; Ichsan, Muhammad; Pedroza, Natalia C.; Laddha, Saurabh
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 1, No 1 (2011): Life Sciences
Publisher : Syiah Kuala University

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Abstract

The discovery of micro RNA (miRNA) in 1993 by Ambros and colleagues has a huge influence in pathogenesis theory, diagnosis and treatment approach of some diseases. Some studies have conducted to seek the association alterations of miRNA expression to incidences and severity of preeclampsia (PE). We have reviewed some studies that conducted to seek the association of miRNA and PE and we discussed the role of various miRNAs in PE pathogenesis. In summary, we have shown that many researchers have given evident that the different placental and plasma miRNA expression is associated with PE. Some studies also identified the novel candidate of miRNAs (and their pathways) that may be of etiologic relevance in the pathogenesis of PE. Base on review, specific miRNA have a role to down regulate of anti apoptosis genes, regulate angiogenics growth factors such as angiogenin, vascular endothelial growth factor (VEGF) B (VEGF-?), cysteine-rich 61 (CYR61), Placental growth factor (PlGF) and VEGF-A that have a role in angiogenesis. miRNA also have a role in  survival, migration, and capillary tube formation of HUVEC by targeted of c-kit. Some miRNAs target genes that participate in immunologic dysfunction, cell adhesion, cell cycle, and signaling. miRNA also have a roles in endothelial cell response to hypoxia, cell differentiation, and survival. A miRNA influence calcium signaling through negative regulations of the calmodulin-coding mRNAs, Mef2a and Gata4, mainly in smooth muscle cells that contribute to PE pathogenesis. These investigations provide novel targets for further investigation of the pathogenesis of PE and these differential miRNAs may be potential markers for the diagnosis and provide a potential therapeutic target for PE. Further investigations on posttranscriptional regulation in PE to evaluate biologic effects of identified miRNAs (including confirmations of miRNA and target gene interactions) are needed
Demokrasi dan Syura: Persepektif Islam dan Barat Ichsan, Muhammad
SUBSTANTIA Vol 16, No 1 (2014)
Publisher : Fakultas Ushuluddin dan Filsafat UIN Ar-raniry Banda Aceh

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Abstract

In this globalization era, the term of democracy has been part of political? culture in Muslim society, which unintentionally hindered the term of syura as? Muslim political reference. In fact, that democracy and syura are two different? concepts in Islamic discourses. The concept of democracy, which is understood,? developed and introduced by West to Muslim, is not very applicable in Muslim? world. It is because the whole concept of western democracy unlikely relevant with? Quran and Prophet Tradition. Western democracy, for instance, positions people as? the owner of the highest sovereignty. It means that whatever the people?s words, they? will be treated as a truth, although they might be wrong. While syura, as Muslim? political reference, perceives Allah as the owner of the highest sovereignty.? Humankind is commanded to apply the concept. If Muslims are going to apply any political will, they must firstly consult to the Quran and Sunnah whether the will is? applicable or not.Abstrak: Kata demokrasi di era globalisasi dewasa ini sudah membudaya dan? dipraktekkan dalam kehidupan masyarakat muslim, sehingga kata syura yang? merupakan acuan umat Islam dalam menjalankan kehidupan dalam masyarakat? hampir dilupakan. Padahal antara demokrasi dan syura terdapat perbedaan dalam? kajian Islam. Demokrasi yang dipahami dan dikembangkan oleh dunia barat kepada? dunia Islam tidak semuanya dapat diterima dan diterapkan di dunia Islam, karena? banyak hal yang terkadang tidak sesuai dengan ketentuan-ketentuan yang telah? digariskan dalam al-Qur?an dan Sunnah Rasulullah Saw. Misalnya kalau demokrasi? yang dipahami barat kedaulatan tertinggi berada di tangan rakyat, apa yang dikatakan? oleh rakyat itulah yang benar walaupun terkadang hal tersebut tidak benar. Sedangkan? dalam Islam, kedaulatan tertinggi berada di tangan Allah Swt, manusia hanya? diberikan amanah untuk melaksanakannya saja. Bila ada hal-hal yang ingin? dilakukan, maka harus dikembalikan kepada al-Qur?an dan Sunnah untuk mengetahui? ketentuan apakah boleh dilaksanakan ataupun tidak.
MODAL SOSIAL DI DALAM MEMPERTAHANKAN KOMUNITAS (Studi Tentang Komunitas Motor Vespa Uvorable Di Pekanbaru) Ichsan, Muhammad; ", Jonyanis
Jurnal Online Mahasiswa (JOM) Bidang Ilmu Sosial dan Ilmu Politik Vol 2, No 2 (2015): WISUDA OKTOBER 2015
Publisher : Fakultas Ilmu Sosial dan Ilmu Politik Universitas Riau

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Abstract

This study describe about the maintain social capital in community vespa uvorable Pekanbaru. Maintaining social capital in the community can be seen through some of the indicators of which is the notion of social capital, social capital in a community, the elements of social capital, the norm in social capital and social networks.The study population was a member of the community joined in uvorable vespa motorcycle community in Pekanbaru. Sampling method used in this study is proportionate stratified sampling techniques and data analysis used is descriptive and qualitative analysis.Data was collected by using questionnaires, interviews and documentation. The theory used is the Social Group Theory and Theory of Social Capital. This study aims to determine the history of the formation of uvorable vespa community, to know what their purpose in forming a community of Vespa unvorable well as to determine the existence of a community of Vespa uvorable Results from this study is that the members of the community joined in Pekanbaru uvorable vespa community have one thought and one purpose the same that they vespa motor fans and they do not want the motor vespa they use now become old items no longer used because of the rapid developments in automotive technology. They want to be recognized by the community with the community joined in a Vespa, the Vespa community uvorable Pekanbaru.Keyword : Social Capital, Social Network, Vespa Community Uvorable in Pekanbaru
KARAKTERISTIK FISIKOKIMIA TEPUNG TEMPE KECAMBAH KEDELAI Astawan, Made; Wresdiyati, Tutik; Ichsan, Muhammad
Jurnal Gizi dan Pangan Vol. 11 No. 1 (2016)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (343.368 KB) | DOI: 10.25182/jgp.2016.11.1.%p

Abstract

This research was conducted to compare physicochemical characteristics of germinated soybean tempe flour (GST flour) and soybean tempe flour (ST flour). Soybean was germinated within 28 hours and then processed into tempe. Germinated soybean tempe and soybean tempe were freeze-dried for 26 hours, and then milled into GST flour and ST flour. The GST flour and ST flour were used for physical and chemical analysis. The used of germinated soybean was proven to affect the quality of flour. GST flour had 53.37 % db protein, 24.97 mg AEAC antioxidant capacity/100 g tempe, 5.08 mg tocopherol/100 g db, 81.75 mg isoflavone/100 g db, and minerals (Ca, P, Fe, Zn) which were higher than that of the ST flour. GST flour also had better quality than that of ST flour, in term of: higher bulk density (0.42 g/ml), lower water activity (0.63), and lower repose angle (39.94o).Keywords: chemical characteristic, germinated soybean tempe, physical characteristic, soybean tempe 
PERBEDAAN PENINGKATAN KEMAMPUAN PEMECAHAN MASALAH DAN BELIEF SISWA ANTARA SISWA YANG DIBERI PMR DENGAN PBM Ichsan, Muhammad
JURNAL TEMATIK Vol 6, No 3 (2016): Jurnal Tematik
Publisher : JURNAL TEMATIK

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jt.v6i3.4539

Abstract

Peneltian ini bertujuan untuk mengetahui: (1) perbedaan rata-rata  peningkatan kemampuan pemecahan masalah antara siswa yang diajarkan dengan PMR dan PBM; (2) perbedaan rata-rata  peningkatan belief (keyakinan) siswa antara siswa yang diajarkan dengan PMR dan PBM; (3) peningkatan kemampuan pemecahan masalah siswa antara yang diajarkan dengan PMR dan PBM; (4) peningkatan belief (keyakinan) siswa antara siswa yang diajarkan dengan PMR dan PBM. Penelitian berbentuk Pre Experimental Design dengan desain penilitian Two Group Pretest-Posttest. Intrumen dalam penelitian ini yaitu tes kemampuan pemecahan masalah dan angket belief siswa. Adapun analisis data menggunakan uji-t dan gain score. Dari hasil penelitian menunnjukkan : (1) terdapat perbedaan kemampuan pemecahan masalah, siswa yang diajarkan dengan PMR lebih baik daripada dengan PBM, hal ini berdasarkan nilai thitung (=0,001) sehingga terdapat perbedaan karena sig (2-tailed) < 0,05 dan thitung bernilai positif; (2) terdapat perbedaan belief (keyakinan) siswa, siswa yang diajarkan dengan PMR lebih baik daripada dengan PBM, hal ini berdasarkan nilai thitung(=0,001) sehingga terdapat perbedaan karena sig (2-tailed) < 0,05 dan thitung bernilai positif; (3) Peningkatan kemampuan pemecahan masalah siswa yang diajarkan dengan PMR lebih tinggi dari PBM, hal ini berdasarkan gain score; (4) peningkatan belief (keyakinan) siswa yang diajarkan dengan PMR lebih tinggi dari PBM, hal ini berdasarkan gain score.Kata kunci: pecahan, pendekatan matematika realistik, kemampuan pemecahan masalah, belief siswa, pembelajaran berbasis masalah
PERAN WANITA TANI TERHADAP KETAHANAN PANGAN RUMAH TANGGA MISKIN DI KECAMATAN SIMPANG TIGA KABUPATEN ACEH BESAR Ichsan, Muhammad; Sofyan, Sofyan; Zakiah, Zakiah
Jurnal Ilmiah Mahasiswa Pertanian Vol 2, No 2 (2017): Mei 2017
Publisher : Fakultas Pertanian, Universitas Syiah Kuala

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Abstract

 Abstrak; Kemiskinan dan ketahanan pangan merupakan dua fenomena yang saling berkaitan, bahkan dapat disebut sebagai hubungan sebab akibat. Dengan demikian dapat dikatakan bahwa keadaan ketahanan pangan yang rentan dapat menjadi sumber kemiskinan, sebaliknya kemiskinan dapat menyebabkan seseorang tidak memiliki ketahanan pangan. Tujuan dari penelitian ini adalah untuk mengetahui kondisi ketahanan pangan rumah tangga wanita tani, mengetahui faktor-faktor apa saja yang mempengaruhi ketahanan pangan pada tingkat rumah tangga wanita tani dan mengetahui peran wanita tani terkait pendapatan dan pendidikan dalam ketahanan pangan rumah tangga di Kecamatan Simpang Tiga Kabupaten Aceh Besar. Hasil penelitian menunjukkan bahwa rumah tangga responden dengan kategori kurang pangan sebesar 45% dan rumah tangga kategori rawan pangan sebesar 55%. Nilai PPH rumah tangga respoden adalah 58,6 menunjukkan tidak seimbangnya mutu gizi rumah tangga responden. Peran wanita tani dalam ketahanan pangan rumah tangga kurang terlihat dikarenakan rendahnya pendapatan dan rendahnya tingkat pendidikan wanita tani. Variable yang berpengaruh signifikan terhadap tingkat ketahanan pangan adalah pendapatan kepala keluarga. Sementara faktor lainnya seperti pendidikan wanita tani, pendapatan wanita tani dan jumlah anggota keluarga tidak berpengaruh secara signifikan.Abstract; The Role of Female Farmers on Food Security Poor Households at Simpang Tiga District in Aceh Besar Regency                     Poverty and food security are the two phenomena that are linked each other, it is also called a causal relationship. It can be said that vulnerable food security condition are the source of poverty, in the other hand, poverty could  cause a person does not have a food security.This study aims to determine the condition of household food security of women farmers, to know the factors which influence food security at the women farmers household level and to know the role of women farmers related to income and education in household food security in Simpang Tiga District Aceh Besar Regency. The results show that the household respondents with less food category by 45% and household food insecurity category by 55%. PPH value of household respondents was 58.6, this  indicates an imbalance in the nutritional quality of the respondents household. The Role of women farmers in household food security is less visible due to low income and low educational levels of women farmers. The head of  households income is significant variable that influence the level of food security is. While the educational factors, income of women farmers, and number of household members is not significant.
Nilai Nutrisi Pakan Ayam Ras Petelur yang Dipelihara Peternak Rakyat di Pulau Lombok Asnawi, Asnawi -; Ichsan, Muhammad; Haryani, Ni Ketut Dewi
JURNAL SAINS TEKNOLOGI & LINGKUNGAN Vol 3, No 2 (2017): Jurnal Sains Teknologi & Lingkungan
Publisher : LPPM Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jstl.v3i2.17

Abstract

Penelitian evalusi nilai nutrisi pakan ayam ras petelur di Pulau Lombok telah dilakukan. Penelitian menggunakan metode survey yang berlokasi di empat Kabupaten di Pulau Lombok yaitu Kabupaten Lombok Barat, Lombok Tengah, Lombok Timur dan Lombok Utara. Pada masing-masing Kabupaten diambil 4 peternak ayam ras sebagai sampel  dan dianalisa di Laboratorium Nutrisi Makanan Ternak Fakultas Peternakan Universitas Mataram. Data dianalisa dan ditabulasi kemudian dipresentasikan dalam bentuk diskriptif. Hasil penelitian menunjukkan bahwa semua peternak ayam ras petelur menggunakan jagung, dedak padi, dan konsentrat sebagai ransum dasar berturut-turut sebesar 43 %±8.13, 22%±3.93, dan 33%±4,83. Campuran pakan tersebut mengandungan protein sebesar 17.21% ±1.23, energi metabolis 2753 ± 63.78, lemak kasar dan serat kasar sebesar 4.03% ±0,2  dan 6.29 % ±0.46, Ca dan P sebesar 3.61% ±0.53 dan 0.51% ±0.03. Rata-rata produksi telur, konsumsi pakan, bobot telur, tebal kerabang dan nilai HU ayam ras di Pulau Lombok berturut-turut sebesar 56%±8.68, 114±31,25 g.ekor-1.hari-1. 61.71±2.49 g. 0.39±0.03 mm dan 90.16±4.33.  Komposisi nutrisi ayam ras petelur tersebut sudah memenuhi Standar Nasioanal Indonesia (SNI), akan tetapi produksi telur masih rendah.Kata Kunci : Mineral, konsentrat, Vitamin ABSTRACT The research of evaluation of nutrient value of laying hens which rearing by farmer in Lombok Island was conducted. Using surveys methode in four locations in Lombok Island i.e. West Lombok, Central Lombok, East Lombok, and North Lombok and four farmers sample of each. Data was analyzed in loboratorium animal nutrition Faculty of Animal Husbandry Mataram University. Data was analized and tabulated and than descriptive presented. The result show that, all of the farmer in Lombok Island use rice bran, maize, and commercial feed as elementary ration with 43%±8.13, 22%±3.93, and 33%±4.83 respectively, in addition, all farmers use feed supplements such as vitamins or mineral. Nutrition value of ration are 17.21% ±1.23 protein, 2753±63.78 metabolizeble energy, 4.03% ±0,2  extract ether and  6.29%±0,46 fibers, Ca and P are 3.61 % ±0.53 and 0.51%±0.03. Average eggs production, feed consumption, egg weight, shell thickness, and Haught Unit (HU) are 56%±8.68, 114±31,25 g.ekor-1.hari-1. 61.71±2.49 g, 0.39±0.03 mm, and 90.16 ±4.33. It can be concluded that nutrient composition of laying hens in Lombok Island according to Indonesian Standard Feed, however, eggs production and quality still low.Key words: Vitamine, concentrate, nutrient
Student Project Management With Project-Based Learning: A Preliminary Study in The Polytechnic Malaysia Sadrina, Sadrina; Lassim, Mohammad Mohd.; Ichsan, Muhammad
CIRCUIT: Jurnal Ilmiah Pendidikan Teknik Elektro Vol 1, No 2 (2015)
Publisher : PTE FTK UIN Ar-Raniry

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Abstract

Finishing the project are the main task for last semester students in Polytechnic. They do the project in order finishing the syllabus without any improving skills for their future work in industry. The common educational system has improved the quantity of graduate but not the quality. Many industrial department dissatisfied with the workforce less of soft skills although they have enough hardskills in their field. Technical and vocational education has given an opportunity for students to develop their interested in technical and vocational program. Project Based Learning (PjBL) is one the various learning based on student oriented learning. Project-Based Learning is a student-centered learning approach based on the principles of constructivism to enhance students’ learning and creativity by solving a real-world problem. The purpose of this study was to asses the project management system by using Project-Based Learning. This study was held at Mechanical Engineering department at Polytechnic Kota Bharu, Malaysia. We used a set of questionnaire and observation into this research. We found Project-Based Learning are suitable for student project management. PjBL has improve students softskill such as communication skills, work in team, solving problem and creative. Futher application of this study will lead to the development of Project-Based Learning implement in other institution to improve student management project.
PSIKOLOGI PENDIDIKAN DAN ILMU MENGAJAR Ichsan, Muhammad
JURNAL EDUKASI: Jurnal Bimbingan Konseling Vol 2, No 1 (2016): JURNAL EDUKASI (JURNAL BIMBINGAN KONSELING) JANUARI 2016
Publisher : Fakultas Tarbiyah dan Keguruan UIN Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/je.v2i1.691

Abstract

Educational psychology is the science of knowledge-that talks about human behavior in the teaching-learning process, and he has a close relationship with science teaching. Where in the process of teaching, educators are required to have adequate knowledge of the material being taught, and also mastered the different methods of delivery so that what is delivered is understandable and easily understood by students. So mastery of educational psychology (educational psychology) is a demand for educators. As defined educational psychology is simply a science which studies human behavior that takes place in the teaching-learning process. While teaching is defined as an activity to organize or manage the environment as well as possible and connect with the child, resulting in a process of learning. In the teaching-learning process, educators should pay attention to the students, the rate of growth and the individual differences that exist between them. As the experts in this case the pupils to classify three types: (1) Type of auditory, easy to accept the lesson by hearing. (2) Type Visual, easy merima learning through sight. (3) Type of methodical, easy to accept the lesson through the motions.
KONSEKUENSI LOGIS PROFESIONALISME ADMINISTRASI GURU DALAM PENDIDIKAN ISLAM Ichsan, Muhammad
Jurnal Ilmiah Didaktika Vol 14, No 2 (2014): Jurnal Ilmiah DIDAKTIKA Februari 2014
Publisher : State Islamic University (UIN) of Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/jid.v14i2.501

Abstract

As educators in schools, teachers have some duties and responsibilities not only to teach, but also to administer the school. Islam gives an overview of the duties and responsibilities for teachers in educational administration. The purpose of this paper is to propose a logical consequence of the professionalism of teachers in Islamic education. The professional duties of teachers as administrators in Islamic Education among others are to run instructional management and management in general such as managing school, utilizing the procedures and mechanisms to carry out their duties and act in accordance with the professional ethics. Besides, they also have to create a good physical condition of classrooms and qualified teaching tool, prepare for daily teaching, create conducive conditions so that learners have willingness to learn, design a lesson plan quarterly and annually, prepare for teaching in accordance with the schedule and lesson plan, evaluate and make a report of students’ achievement to several parties, make some revision based on the results of the evaluation, get to know the talents, interests and abilities of students, help students to improve and direct the talents and interests of students, participate and maintain reputation of the institution and write a report of teaching and learning activities. All in all, teachers also have a responsibility given by Allah to do their best in teaching.