Darwin Karyadi
Nutrition Research Institute, "Semboja Unit" Bogor, Ministry of Health

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EFEKTIVITAS PEMBERIAN CGF 40% DALAM MEMPERCEPAT PENINGKATAN TROMBOSIT PADA PENDERITA DEMAM BERDARAH DENGUE Effendi, Adi Teruna; Sediono, M; Suksmono, HS; Erwanto, B; Effendi, Yekti Hartati; Dewi, Mira; Karyadi, Darwin
Jurnal Gizi dan Pangan Vol. 5 No. 3 (2010)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.694 KB) | DOI: 10.25182/jgp.2010.5.3.130-138

Abstract

Aim of this study was to evaluate the effectiveness of CGF 40% in hastening the recuperation, as indicated by reduced length of hospital stay, improvement in clinical status, increase in platelets, and reduction in the hemoconcentration. The study group comprised of 84 consecutive DHF patients, 42 male and 42 female subjects, who were randomized into the control group receiving the WHO standard therapy and the intervention group receiving CGF 40% and the standard therapy. Hemoglobin, hematocrite and thrombocyte counts were taken daily until the subjects were free of the symptoms and signs of DHF, and the thrombocyte count read >100.000. The results were analyzed statistically, student t test and quadratic regression, using SPSS 16 software. The average length of recuperation time in the intervention and control groups were 2.76 days and 4.43 days respectively (p=0.000). Recuperation times of subjects with thrombocyte counts <50,000 and >50,000 of the intervention group (3,09 and 2,37 days) and the control group (4,2 and 4,5 days) were different significantly (p=0.016 and 0.000). When analized specifically in the treatment group, the recuperation time of those with thrombocyte counts <50,000U (2.37 days) did not differ to those with >50,000 (3.09 days) with p=0.112. Using quadratic regression, the increase in thrombocytes, reduction in hemoglobin concentrations and hematocrite were faster in the intervention group when compared to the control group, with R2 almost reaching 1. The study disclosed that administration of CGF 40% could reduce the recuperation time and improved the hemoconcentration, which presumably demonstrated the concept of regenerative medicine as indicated by the repairmen of vascular permeability.
PSYCHOSOCIAL ASPECTS OF MOTHERS OF MALNOURISHED AND WELL-NOURISHED CHILDREN Sulaiman, Zein; Husaini, M. A.; Kartono, Joko; Jenie, Rini Azwein; Sihadi, Sihadi; Matulessy, Paul F.; Karyadi, Darwin
Paediatrica Indonesiana Vol 36 No 11-12 (1996): November-December 1996
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi36.11-12.1996.248-57

Abstract

In order to determine whether differences in sociopsychological environĀ­ment and related factors exist between malnourished and well-nourished children, a study on 126 underfive children was carried out in Bogor, West Java, Indonesia. The children were grouped into severely malnourished, mild-moderately malnourished, and well-nourished children. Each group consisted of 42 children, and they were selected from die same surrounding which have fairly same housing condition, age, and sex. Differences were found between the three groups on parent's education, the birth order of the child, the expenditure per capita, and breast feeding history. However, there was no significant difference on knowledge about health and nutrition, mother and child relationship. It was observed that children who were never breastfed had a tendency to be severely or moderately malnourished. The mothers who were doing only household chores were worried about the future of their children; on the other hand, the mothers who have more contact with community (monthly welfare movement meetings, and other activities outside homes) have a tendency to have well-nourished children. The proposed hypothesis that mother and child interaction affects the level of die nutritional status of the children requires more testing in a more comprehensive study.