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Journal : HAYATI Journal of Biosciences

THE USE OF SELECTED BIOMARKERS, PHAGOCYTIC AND CHOLINESTERASE ACTIVITY TO DETECT THE EFFECTS OF DIMETHOATE ON MARINE MUSSEL (MYTILUS EDULIS) YAQIN, KHUSNUL; LAY, BIBIANA WIDIATI; RIANI, ETTY
HAYATI Journal of Biosciences Vol. 15 No. 1 (2008): March 2008
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (70.987 KB) | DOI: 10.4308/hjb.15.1.32

Abstract

Effects of organophosphorous pesticide, dimethoate on blue mussels, Mytilus edulis using selected biomarkers have been studied. Mussels were exposed to serial dilutions of dimethoate, 7.88, 15.75, 31.35, and 63.00 �µg/l including positive and negative controls for 14 days. The suppression effects of dimethoate on phagocytic activity significantly occurred at two lowest concentrations of dimethoate (7.88 and 15.75 �µg/l), but stimulation effects significantly emerged at the following highest concentrations (31.35 and 63.00 �µg/l). The declining tendency of the cholinesterase (ChE) activity (23% lower than the control) appeared when mussels exposed to 7.88 and 15.75 �µg/l dimethoate. Moreover, the significant inhibition of the ChE activity occurred at 31.35 �µg/l dimethoate exposure. This study suggested that the phagocytic and the ChE activity are useful biomarkers for assessing the affects of organophosporous pesticide, dimethoate on neuro-immune system of blue mussels, M. edulis. Key words: dimethoate, cholinesterase, phagocytic, blue mussels