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Hubungan Status Gizi dengan Rata-Rata Usia Menarche Fitriana, Ema Nur; Moelyo, Annang Giri; Yuliadi, Istar
Nexus Kedokteran Komunitas Vol 1, No 2 (2012): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Menarche is the first menstrual period in woman reproduction cycle. Several epidemiology studies shows that the onset of menarche was became earlier. This condition was supposed to be related with the increases of nutritional status. The aim of this study was to identify the  association between Nutritional status with the mean of age of menarche in SD N 1 Kleco Surakarta (elementary school) students. Method : An analytical observational study using a cross sectional design, was performed in SDN 1 Kleco Surakarta (elementary school) students within the onset of menarche or the 3rd-6th grade’s student on April 2012.  Nutritional status was measured anthropometically for calculating and plotting the body mass index (BMI) for age based on CDC 2000 growth chart. An interview was done to know the age of menarche. The association between nutritional status with the mean age of menarche had been analyzed by Kruskal Wallis SPSS 17 for windows, meanwhile the association between nutritional status with episode of menarche had been analyzed by Chi Square. Result : This study shows 48 (26,8%) subjects were underweight, 96 (53,6%) subject were normal, 25 (13,9%) subject were overweight, and 10 (5,7%) subject were obese.  Twenty six subjects (14.5%) have had period of menarche when we did this study. Means of age of menarche is 10.72 (SD 0.89) years old; the youngest age of menarche is 9 years old (2 subjects, 7.7%). Chi-square test showed no association between nutritional status and episode of age of menarche (odd ratio 1.64, 95%CI 0.63-4.39). Kruskall-Wallis test revealed no association between overweight-obese girls and means of age of menarche (p =0.906,p>0.05). Conclusion : There is no association between nutritional status with the mean of age of menarche in SD Negeri 1 Kleco Surakarta’s student. Keywords: Nutritional Status - Age of Menarche 
Perbedaan Prevalensi Obesitas antara Etnis Jawa, Tionghoa, dan Arab pada Anak Sekolah Menengah Pertama di Surakarta Murti, Zenia Purnama; Moelyo, Annang Giri; Widardo, .
Nexus Kedokteran Komunitas Vol 2, No 3 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background:Obesitycauses many health problems in childhoodsuch ascardiovasculardisease, diabetes, musculoskeletaldisorders, cancersthat causemorbidity and mortalityin adulthood. Ethnicity is a risk factor for obesity. Ethnicity affect eating habits, genetic, amount of energy expenditure, fat distribution and tendency of obese in a child. The aim of this study was to analyze prevalence of obesity in Junior High School Children in Surakarta based on ethnic differences (Javanese, Chinese, and Arabian). Methods:This was a cross-sectional analytic study to 395 students of 8th grade in SMP Negeri 4 Surakarta, SMP Bintang Laut Surakarta, and SMP Diponegoro Surakarta (junior high school) that consist of Javanese, Chinese, and Arabian. Samples were collected by purposive sampling technique. Inclusion criteriaswere students of 8thgrade,parentshave thesameethnicity, and signed an informed consent. Exclusion criterias werechildrenwithedema, have achronicillness, taking medicationlong-termandconditions ofhandicapped.The questionnaire was used to know the ethnic of the child. Body mass index was used to define obesity status with Z-score >+2 SD based on  World Health Organization in 2007 growth chart. Data were analyzed by Chi-Square test. Results:This research shows 246 (63%) subjects were Javanese, 79 (20%) subjects were Chinese, and 70 (17%) subjects were Arabian.  Twenty seven subjects (6.84%) were obese and threehundred andsixty-eight subjects (93.16%) were not obese. Obese prevalence was 4.5 % among Javanese, 8.9 % among Chinese, and 12.9 % among Arabian.It shows a significant differences in the prevalence of obesity among the three ethnics (p=0,036; p < 0.05). Conclusions:There are significant differences in the prevalence of obesity among Javanese, Chinese, and Arabian Ethnic in junior high school children in Surakarta. Keywords:ethnicity, obesity, children
Perbedaan Usia Menarche Siswa SMP Ditinjau dari Etnis Jawa, Tionghoa dan Arab di Surakarta Rakhmawati, Isna Noor; Moelyo, Annang Giri; Karini, Suci Murti
Nexus Kedokteran Komunitas Vol 2, No 3 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background :Menarche is the first menstrual period in woman reproduction cycle. In many studies, race and ethnicity has been shown to contribute to the age of menarche. The objective of thisstudy is to identify the difference of menarche’s agein junior high school girls among Javanese, Chinese and Arabian ethnic in Surakarta. Method :This wasa cross sectional study. Two hundred and thirty healthy Javanese, Chinese and Arabian students from 8th grade of  3 junior high schools in Surakarta were fulfilledthe restriction criteria. Age of menarche and ethnicity of the students were collected through a questionnaire. The difference of menarche’s ageamong those three ethnics were analyzed by Kruskal Wallis in SPSS 17.0 for Windows. Result :Of 230 subjects, 151 (65.65%) students were Javanese, 42 (18.26%) students were Chinese and 37 (16.09%) students were Arabian. Two hundred and fourteen (93.04%) students had recently experienced menarche. The mean age of menarche was 11.9 (SD 0.85) years old and the youngest age of menarche was 9.9 years old. The mean age of menarche in Javanese was 12 years old, in Chinese was 11.8 years old and in Arabian was 11.9 years old. Kruskal Wallis test revealed no significant difference found in the age of menarche among Javanese, Chinese and Arabian (p = 0.567). Conclusion :There is no difference of menarche’s age in junior high school girls among Javanese, Chinese and Arabian ethnic in Surakarta. Keyword :Ethnic,Menarche’s Age  
Hubungan Lama Sakit dengan Status Gizi Anak Penderita Talasemia di RSUD Dr. Moewardi Anisa, Ilma; Riza, Muhammad; Moelyo, Annang Giri
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Systemic complications that occur in children with thalassemia like hepatomegaly, hemosiderosis, bone deformities can affect nutrition disorder and growth retardation. The longer someone has suffered thalassemia, the more likely for the systemic disorder occurred. The aims of this study to find out the correlation between duration of illness with nutritional status of children with thalassemia in Dr. Moewardi Hospital. Methods: This is an observational analytic study using cross sectional design which was conducted from April to May 2013. Thirty children with thalassemia in the Dr. Moewardi Hospital were fulfill the restriction criteria. The duration of illness was acquired from medical record, while the nutritional status was obtained through measurements of weight, height, and the mid-upper arm circumference. The correlation between the duration of illness, gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status was analyzed by using Spearman test followed by the multivariate logistic regression analysis. Results: Spearman test analysis showed no significant correlation between duration of illness with nutritional status in children with thalassemia according to the weight/age and height/age indicator (p = 0,403 and p = 0,408). From the result of analysis on correlation between gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status according to the weight/age and height/age indicator (p > 0,05). Conclusions: There is no significant correlation between the duration of illness with the nutritional status of children with thalassemia according to the weight/age and height/age indicator in Dr. Moewardi Hospital. There is no correlation between gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status. Keywords: Duration of Illness, Nutritional Status, Thalassemia 
Hubungan antara Status Gizi dan Infeksi Blastocystis hominis pada Pasien Bangsal Anak RSUD Dr. Moewardi Surakarta Sungkar, Nabila Adib; Dirgahayu, Paramasari; Moelyo, Annang Giri
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background :Blastocystis hominis is one of the most common protozoans found in worldwide human intestinal tract. In Indonesia, its prevalence reached 60%, the highest prevalence found in children less than 6 years old (25%). Epidemiological and clinical researches show that a defect of nutritional status can inhibit immunity response and increase risk of infectional disease. This study aimed to analyze the correlation between nutritional status and Blastocystis hominis infection among children in RSUD Dr. Moewardi Surakarta. Methods :This study was an observational analytical research using cross-sectional approach. The subjects were every pediatric ward patient in RSUD Dr. Moewardi Surakarta period July-August 2013. A total of 50 subjects were selected using total sampling method. Fresh stool samples were examined using Ziehl-Neelsen staining method. Data were analyzed by multiple logistic regression analysis and processed with the Statistical Product and Service Solutions (SPSS) 17.0 for Windows. Results :Blastocystis hominis was found in 36/50 (72%) stool samples. Poor nutritional status patients in pediatric ward of RSUD Dr. Moewardi Surakarta have the same risk to be infected by Blastocystis hominis compared to good nutritional status patients (OR = 1.04 ; p < 0.97). But children aged under 2 years old have lower risk to get infected by Blastocystis hominis compared to children over 2 years old (OR = 29,333 ; p < 0,001) Conclusion :There is not any significant correlation between nutritional status and Blastocystis hominis infection among children in RSUD Dr. Moewardi Surakarta. Keywords :Blastocystis hominis, nutritional status 
Sitting height, sitting height/height ratio, arm span and arm span-height difference of healthy adolescents in Surakarta, Indonesia Moelyo, Annang Giri; Yogasatria, Lucky; Setyawan, Yusak Aditya; Rokhayati, Evi
Paediatrica Indonesiana Vol 58 No 3 (2018): May 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (847.768 KB) | DOI: 10.14238/pi58.3.2018.138-45

Abstract

Background Sitting height, sitting height/height ratio (SHR), arm span, and arm span-height difference (AHD) are indices to diagnose conditions of disproportion. Reference data on sitting height, SHR, arm span, and AHD for Indonesian children are limited. Objective To compile reference data on sitting height, SHR, arm span, and AHD in Indonesian adolescents, and to compare these indices for boys and girls at various ages. Methods A population-based survey was conducted from August 2016 to November 2017 in three high schools in Surakarta, Central Java, Indonesia. A convenience sampling method was employed to recruit healthy adolescents without history of chronic disease, history of physical trauma, and/or physical disabilities. All subjects underwent anthropometric measurements (height, weight, sitting height, and arm span), and their ethnic origins were noted. The lambda-mu-sigma (LMS) method was used for reference construction. Results Of 639 subjects, 42% were male. Body mass index (BMI) values were similar between males and females. Mean height, weight, sitting height, and arm span of males were greater than those of females. The mean male and female SHRs were 51.1 (SD 1.6) % and 51.0 (SD 1.6) %, respectively (P=0.36), while the mean AHDs were 4.2 (SD 4.5) cm and 3.4 (SD 4.1) cm, respectively (P=0.02). The formula to estimate height based on arm span in males was [height = (0.78 x arm span) + 32.14] in cm. The formula in females was [height = (0.66 x arm span) + 50.59] in cm. Conclusion There was no significant difference in SHR between male and female adolescents. However, males haVE significantly larger mean AHD than females. We provide references on sitting height, SHR, arm span, and AHD in male and female adolescents.
Perbedaan Kadar Thyroid Stimulating Hormone dan Free Thyroxine pada Pasien Talasemia Β-Mayor dengan Kelasi Besi Deferasirox dan Deferiprone Krisbiyantoro, Aries -; Salimo, Harsono; Moelyo, Annang Giri
Sari Pediatri Vol 19, No 4 (2017)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (78.075 KB) | DOI: 10.14238/sp19.4.2017.209-13

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Latar belakang. Talasemia β Mayor merupakan kelainan herediter yang disebabkan gangguan produksi rantai globin. Transfusi rutin menyebabkan kelebihan besi yang tertimbun dalam jaringan sehingga menyebabkan kardiomiopati, gangguan liver, dan komplikasi endokrin. Tiroid merupakan kelenjar endokrin yang berperan penting bagi anak. Pengendapan besi di kelenjar tiroid dapat menyebabkan gangguan fungsi tiroid. Pemberian kelasi besi deferiprone dan deferasirox dan pengaruhnya pada kadar TSH dan FT4 perlu dievaluasi lebih lanjut.Tujuan. Menganalisis perbedaan kadar TSH dan FT4 pada pasien anak dengan talasemia β mayor menggunakan kelasi besi deferiprone dan deferasirox Metode. Penelitian analitik dengan rancangan potong lintang (cross sectional) terhadap 43 pasien talasemia β mayor anak berusia 9-18 tahun pada bulan April sampai Juni 2017. Pemilihan subjek dilakukan secara consecutive sampling. Data di analisis dengan SPSS 20 mengunakan uji t independen dan uji man whitney.Hasil. Rerata usia pasien 12,5+3,12 tahun. Rerata kadar TSH kelompok deferiprone dan deferasirox adalah 3.051,78 IU/ml dan 2.351,29 IU/ml. Sedangkan rerata kadar FT4 untuk kelompok deferiprone dan deferasirox 15.424,12 mmol/l dan 15.822,75 IU/ml. Tidak terdapat perbedaan kadar TSH dan FT4 pada kelompok yang mendapatkan deferasirox dan deferiprone berturut-turut nilai TSH (p=0,148; p>0,05) dan FT4 (p=0,836; p>0,05). Kesimpulan. Tidak terdapat perbedaan kadar TSH dan FT4 pada pasien talasemia beta mayor yang mendapatkan kelasi deferasirox maupun deferiprone.
LUNG ULTRASOUND IN DIAGNOSING NEONATAL RESPIRATORY DISTRESS SYNDROME: A META-ANALYSIS Ferdian, Hanum; Wahid, Dian Ibnu; Samad, Samad; Wardani, Anggun Esti; Alam, Guntur Surya; Moelyo, Annang Giri
Paediatrica Indonesiana Vol 59 No 6 (2019): November 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.302 KB) | DOI: 10.14238/pi59.6.2019.340-8

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Background Neonatal respiratory distress syndrome (NRDS) is commonly diagnosed by clinical sign and symptoms, blood gas analysis, and chest x-ray. In the past, lung ultrasound (LUS) was not standard for NRDS examination. Many studies show that ultrasound diagnostic tool for NRDS is accurate, reliable, low cost, easy to use, and safe because due to no ionizing radiation. Objective To determine the sensitivity and specificity of LUS in diagnosing NRDS. Methods This meta-analysis study was conducted LUS as a diagnostic tool for NRDS. Inclusion criteria were all studies from PubMed, Embase, and The Cochrane Library, without any limitation on published journals, as well as using keywords or search terms of ultrasound, neonatal, and respiratory distress syndrome. Statistical analysis was undertaken using MedCalc® version 18.2 software. Results Seven studies with a total of 580 patients met the inclusion criteria. Proportional meta-analysis obtained random effects models, with total sensitivity of LUS was 97.2% (95% CI for I2 74.24 to 92.88; P<0.0001) and specificity of LUS was 94.8% (95% CI for I2 88.60 to 98.03; P<0.00001). Conclusion Lung ultrasound should be considered as a diagnostic tool for NRDS because it is high in sensitivity and specificity, inexpensive, safe, as well as limited radiation exposure.
LEVOTHYROXINE USE AND THYROID GLAND VOLUMES IN CHILDREN WITH AUTOIMMUNE THYROIDITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS Moelyo, Annang Giri; Widyahening, Indah Suci; Tridjaja, Bambang
Paediatrica Indonesiana Vol 59 No 4 (2019): July 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (764.737 KB) | DOI: 10.14238/pi59.4.2019.202-10

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Background Autoimmune thyroiditis may manifest as overt hypothyroidism, subclinical hypothyroidism, euthyroidism, or hyperthyroidism in children. Although there is no consensus on treating euthyroidism and autoimmune thyroiditis in children, some studies have demonstrated the efficacy of levothyroxine in reducing thyroid volume, improving thyroid function, and stabilizing the immunological process. Objective To determine the effect of levothyroxine on thyroid gland volume changes, thyroid function, and thyroid antibodies in euthyroid children with autoimmune thyroiditis. Methods We performed a literature search of electronic databases (the Cochrane Library, MEDLINE, EBSCO, ProQuest, clinicaltrials.gov, and other sources, as well as a non-electronic search (searching journals and conference proceedings by hand) to identify studies of euthyroid children with autoimmune thyroiditis published by August 2018. Only English-language articles were included in the search (electronic and non-electronic). Randomized controlled trials that compared levothyroxine with a control (placebo or no treatment) in euthyroid children with autoimmune thyroiditis were selected. The outcome measures were thyroid volume changes, thyroid function, and thyroid antibody levels in euthyroid children with autoimmune thyroiditis. Two authors independently extracted the data, assessed the risk of bias, and analyzed the pooled data from the included studies using a random effects model. The same authors performed a sensitivity analysis. Results We identified 57 studies. Of these, three studies, involving 97 subjects (51 subjects in an intervention group and 46 subjects in the control group) were selected for inclusion in a systematic review/meta-analysis. The meta-analysis revealed a significant difference in mean thyroid volume changes between the two groups (-1.10 SDs; 95%CI -1.56 to -0.64; P<0.0001; I2=6%). The mean difference in the thyroid-stimulating hormone (TSH) change of the two groups was -1.82 mU/L (95%CI -3.52 to -0.11; I2=87%; P=0.04). The standardized mean difference in free thyroxine (fT4) change of the two groups was 0.82 pmol/L (95%CI -1.14 to 2.78; I2=89%; P=0.41). Conclusion In euthyroid children with autoimmune thyroiditis, levothyroxine treatment reduces the thyroid volume better. The TSH level change in the intervention group is better than those in the control group. Levothyroxine treatment did not significantly improve free T4.
AGE AT MENARCHE AND EARLY MENARCHE AMONG HEALTHY ADOLESCENTS Moelyo, Annang Giri; Wulandari, Anindita; Imas, Oktania; Rahma, Ulfa Puspita; Hidayah, Nurul; Kesumaningtyas, Cempaka; Nur, Fadhilah Tia; Nugroho, Hari Wahyu
Paediatrica Indonesiana Vol 59 No 1 (2019): January 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.554 KB) | DOI: 10.14238/pi59.1.2019.33-7

Abstract

Background Menarche is an important indicator of female adolescents? health and also population health. Age at menarche tends to decrease in many countries. Early menarche that defined from the lowest quartile of age at menarche, associated with some physical and psychological problems. Objective To determine the mean age at menarche, the prevalence of early menarche among healthy adolescents in Surakarta and its association to nutritional status. Methods This cross-sectional study was conducted in 5 schools (3 junior and 2 senior high schools) in Surakarta, Central Java, Indonesia, from September 2016 to March 2018, by consecutive sampling technique. We included menarched healthy female students whose parent provided informed consent and without consuming any routine medication. Data were derived from self-reported questionnaire and measurements of body weight; body height; and body mass index (BMI) by calculated based on weight/height2(kg/m2). Results Of 835 eligible subjects, the mean age at menarche was 12.0 (SD 1.1) years (range 8.8-15.1 years) and the prevalence of early menarche was 11.1%. The peak of age at menarche were at 11,12, and 13 years (24.3%, 36.2%, and 23.9%, respectively) and almost 99.04% of subjects had menarche at 14 years old. The proportion of early menarche between subjects birth 1997-2001 and 2002-2007 were 8.4% and 16.1%. Early menarche associated with overweight-obese in adolescents (odd ratio 2.14; 95%CI 1.21 to 3.76). Conclusion The mean age at menarche of healthy adolescents in Surakarta is younger than other previous studies in Indonesia. Early menarche was significantly a risk for overweight/obese in adolescents.