Alex Pangkahila
Program Studi Magister Fisiologi Olahraga Universitas Udayana

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CORE STABILITY EXERCISE LEBIH BAIK MENINGKATKAN AKTIVITAS FUNGSIONAL DARI PADA WILLIAM’S FLEXION EXCERCISE PADA PASIEN NYERI PUNGGUNG BAWAH MIOGENIK Pramita, Indah; Pangkahila, Alex; -, Sugijanto
Sport and Fitness Journal Volume 3, No.1, 2015
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

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Myogenic low back pain is pain around of the lower back mucle caused by disorder or abnormalities in the elements of muscles and tendons without neurological disorders. Myogenic low back pain may result in pain, muscle spasm and muscle imbalance, so that the stability of abdominal muscles and low back decreased, lumbar mobility is limited, resulting in a decrease in functional activity. The exercise was usually given in a hospital Short Wave Diathermy combined with William's Flexion Exercise (WFE). The existence of a new method of core stability exercise (CSE) is very important for patients with myogenic low back pain. CSE was function to activate the harmonious movement between the four core muscle groups. The activation of these four core muscles will given stability on the lower back. The purpose of this study to determine core stability exercise is better than William's Flexion Exercise increases the functional activity in patients with myogenic low back pain. This study uses a quasi experimental design with pre-test and post-test control group design. The experiment was conducted in a clinic in Denpasar. Subjects were 28 patients who fulfill the criteria were established of the researchers. The increasing of functional activity was measured with the Oswestry Disability Index (ODI) before and after training. Subjects were divided into two groups, they are the treatment group was given SWD and CSE three times a week and a control group given SWD and WFE three times a week. The results of statistical test was obtained, occur of decreasing in ODI scores in the first group with p = 0.001 and in the second group with p = 0.001. It means that the first group and the second group alike can increase the functional activity significantly. From the comparative test data by t-test using the difference data in the two groups was obtained the value p=0.001, which means significantly. The difference mean value ODI in first group as 28,86% although the difference ODI in the second group as 15,41%.  From the results of the research can be concluded that the core stability exercises is more increase the functional activity than William's Flexion Exercise in patients with myogenic low back pain. The study is expected to be beneficial in patients with myogenic low back pain to improving functional activity.
PEMBERIAN EKSTRAK FLORET PISANG RAJA (MUSA X PARADISIACA) MENCEGAH PENURUNAN KADAR SUPEROKSIDA DISMUTASE (SOD) PADA HATI MENCIT (MUS MUSCULUS) BALB/C DENGAN AKTIVITAS FISIK BERLEBIH Irtanto, Okky; Pangkahila, Alex; Aman, IGM
JURNAL BIOMEDIK : JBM Vol 9, No 3 (2017): JURNAL BIOMEDIK : JBM
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.9.3.2017.17338

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Abstract: Overtraining accelerates aging due to the excessive production of free radicals that can cause oxidative stress. Banana floret extract contains bioactive compounds with antioxidant capacity which can increase the body's defence to deal with the oxidative stress by increasing the level of superoxide dismutase (SOD). This study was aimed to prove that the banana (Musa x paradisiaca) floret extract could prevent the decrease of superoxide dismutase (SOD) levels in overtraining-induced mice (Mus musculus) BALB/c liver. This was a true experimental study with the post-test only control group design. Subjects were 36 male mice (Mus musculus), BALB/c strain, 12 weeks old, weighing 20-22 g, which were divided into two groups with 18 mice each. The control group (P0) was treated with a placebo of 1 ml aquadest and overtrained for 14 days meanwhile the treatment group (P1) was treated with banana (Musa x paradisiaca) floret extract of 400 mg/kgBW/day and overtrained for 14 days. The results showed that after 14-day treatment, the mean SOD level in the liver tissue of the P0 group was 568.82±9.558 U/mg protein whereas in the P1 group was 588.37±10.629 U/mg protein (P < 0.01). The t-independent test showed a t value of -5.804 and a P value of 0.000 which indicated that after treatment, the levels of SOD in liver tissue of both groups were significantly different. Conclusion: Banana (Musa x paradisiaca) floret extract could prevent the decrease of superoxide dismutase (SOD) levels in the liver tissue of overtraining-induced mice (Mus musculus) BALB/c.Keywords: banana floret, SOD, liver, overtrainingAbstrak: Aktivitas fisik berlebih mempercepat penuaan karena meningkatkan produksi radikal bebas yang dapat menyebabkan stres oksidatif. Ekstrak floret pisang mengandung senyawa bioaktif dengan kapasitas antioksidan yang dapat meningkatkan pertahanan tubuh dalam menghadapi stres oksidatif melalui peningkatan kadar superoksida dismutase (SOD). Penelitian ini bertujuan untuk membuktikan bahwa pemberian ekstrak floret pisang raja (Musa x paradisiaca) dapat mencegah penurunan kadar SOD pada hati mencit (Mus musculus) BALB/c dengan aktivitas fisik berlebih. Jenis penelitian ialah eksperimental murni dengan post test only control group design. Subjek penelitian ialah 36 ekor mencit (Mus Musculus) BALB/c, jantan, berumur 12 minggu, berat badan 20-22 gr, yang dibagi menjadi dua kelompok masing-masing berjumlah 18 ekor mencit. Kelompok kontrol (P0) diberikan plasebo berupa aquadest sebanyak 1 ml dengan aktivitas fisik berlebih selama 14 hari, dan kelompok perlakuan (P1) diberikan ekstrak floret pisang raja (Musa x paradisiaca) dosis 400 mg/kgBB mencit per hari dicampur aquadest hingga 1 ml dengan aktivitas fisik berlebih selama 14 hari. Hasil penelitian menunjukkan rerata kadar SOD jaringan hati pada kelompok kontrol (P0) sesudah perlakuan (post-test) ialah 568,82±9,558 U/mg protein, sedangkan pada kelompok perlakuan (P1) ialah 588,37± 10,629 U/mg protein. Analisis kemaknaan dengan T-Independent mendapatkan nilai t= -5,804 dan nilai P = 0,000 yang menunjukkan bahwa sesudah perlakuan (post-test), kadar SOD jaringan hati pada kedua kelompok berbeda sangat bermakna. Simpulan: Ekstrak floret pisang raja (Musa x paradisiaca) dapat mencegah penurunan kadar SOD pada hati mencit (Mus musculus) BALB/c dengan aktivitas fisik berlebih.Kata kunci: floret pisang raja, SOD, hati, aktivitas fisik berlebih
ASSOCIATION BETWEEN CADRE KNOWLEDGE, FEEDING BEHAVIOURS AND DAILY INTAKE WITH CHANGES IN NUTRITIONAL STATUS OF UNDERNOURISHED CHILDREN IN KAWANGU HEALTH CENTRE, EAST SUMBA Kareri Hara, Maria; Tresna Adhi, K.; Pangkahila, Alex
Public Health and Preventive Medicine Archive Vol 2 No 1 (2014): Public Health and Preventive Medicine Archive
Publisher : Program Magister Ilmu Kesehatan Masyarakat Universitas Udayana

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Abstract

Background and purpose: In 2012, in Eastern Sumba 21% of children under 5 were malnourished; at the KawanguHealth Centre (KHC) it was reported that 3.4% of children were underweight. This study was aimed to investigaterelationships between cadre knowledge, motivation and behavior of child carers with the nutritional status changes ofchildren from KHC. feeding behaviors and change in nutritional status. Data on cadre knowledge and motivation was collected through aself-administered questionnaire and through interviews conducted with child carers. Anthropometric measurementswere taken to assess changes in nutritional status of children. Analysis used univariate and bivariate chi-squared test. Results: Results indicated respondents were aged 26-35 (41.2%), had elementary school education (56.2%), werefarmers (91.2%), had experience as cadres for 2 years (53.8%), were trained (72.5%) and had been involved with theprogram less than &lt;45 days (91.2%). About 55.0% of respondents indicated a high level of knowledge and were highlymotivated (86.2%). Carers indicated a fair behaviour change (51.2%), although there was an increase in improvement innutritional status (63.8%). There was relationship between cadre knowledge and changes in feeding behaviours(p=0.016), but not with cadre motivation (p=0.500). There was an association between feeding behavior (p=0.032) withchanges in nutritional status.
PELATIHAN LARI SIRKUIT 2 X 10 MENIT DAN PELATIHAN LARI KONTINYU 2 X 10 MENIT DAPAT MENINGKATKAN VO2 MAX TAEKWONDOIN PUTRA KABUPATEN MANGGARAI - NTT Sesilia Noy, Regina; Pangkahila, Alex; Jawi, I Made
Sport and Fitness Journal Volume 2, No.2, 2014
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

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Abstract

VO2 max is very important in everyday life, so as to facilitate any physicalactivity, specially for athletes in order to achieve maximum performance. In aneffort to increase VO2 max training should be carried out regularly, measured andplanned. This study aims to determine the increase in VO2 max through circuittraining run and run continuously. The sample is taekwondoin son Manggarai-NTTwith an average age of 15 years. This study is an experimental study with the studydesign used was Randomized Pre and Post Test Group desigen. With a totalsample of 7 people in each group. Samples were randomly selected. Treatmentgroup 1 (KP1) given training run circuit 2 x 10 minute and Treatment Group 2(KP2) are given continuous training run 2 x 10 minute. Training carried out for 6weeks with a frequency of four times a week starting at 17:00 to 18:00 pm locatedat Frans Sales Lega Airport Manggarai-NTT. The analysis showed an increase inVO2 max was significantly (p &lt;0.05) against both groups fled. In both groups thecircuit run by Pulse Oxymeter and Norma Cooper an increase in VO2 max with p&lt;0.05, as well as a continuous run either by Pulse Oxymeter and Norma Cooperwith an increase in VO2 max value of p &lt;0.05. The results of this analysis meansthat either the training or circuit training run run continuously to improve VO2max. Based on a comparison of test data by an independent test after training inboth groups either by Pulse Oxymeter and Norma Cooper in get p values &gt; 0.05, orthere is no significant difference. Based on these results it can be concluded thatthe run circuit training and continuous training run together can increase VO2 maxand there was no significant difference. The results of this study are expected toincrease the knowledge of coaches, teachers and taekwondoin to perform trainingon a regular basis and are also expected to do similar research that examines VO2max with different training.
INTERVENSI PROGRESSIVE MUSCLE RELAXATION LEBIH MENURUNKAN TEKANAN DARAH DARI PADA SLOW STROKE BACK MASSAGE PADA PASIEN HIPERTENSI DERAJAT I YANG MENGONSUMSI OBAT ANTI HIPERTENSI DI BADUNG Juni Antari, Ni Komang Ayu; Pangkahila, Alex; Ali Imron, Muh.; Griadhi, I Putu Adiartha; Sri Handari Adiputra, Luh Made Indah; Irfan, Muh.
Sport and Fitness Journal Volume 7, No.1, Januari 2019
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.881 KB) | DOI: 10.24843/spj.2019.v07.i01.p12

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ABTSRACT Introduction: Physical exercise as anticipate of hypertension along with nutrition and medicines. One of physical exercise that can be applicated here is relaxation techniques which is showed positive impact in decreased blood pressure. Objective: Determine the difference between PMR intervention with SSBM intervention to reduce blood pressure for grade I hypertension patients whose consumed anti-hypertension medicine in badung regency. Methods: Experimental method Pre and post-test control group design and used 24 subjects, divided in to 2 groups, in which the experimental group I (n=12) received progressive muscle relaxation (PMR) while the treatment group 2 (n=12) received slow stroke back massage (SSBM). Intervention is given 3 times a week for 4 weeks. This study was using simple random sampling. Blood pressure was measured by sphygmomanometer and stethoscope. Result: Independent Sample T-test showed there was significant difference between Group 1 and Group 2 which (p&lt;0.05) for systolic and diastolic blood pressure. Conclusion: Progressive muscle relaxation intervention decrease blood pressure more than slow stroke back massage intervention in patients grade I hypertension whose consumed anti-hypertension medicine in Badung Regency.Keywords: progressive muscle relaxation, slow stroke back massage, grade I hypertension, blood pressure
PENGATURAN POLA HIDUP DAN AKTIVITAS FISIK MENINGKATKAN UMUR HARAPAN HIDUP Pangkahila, Alex
Sport and Fitness Journal volume 1, no 1, 2013
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

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Human life expectancy is very dependent on the process of aging, and the aging process is not nature but is caused by several factors including: excessive activity (Wear and Tear Theory), hormonal (Neuroendocrinology Theory), genetic (The Genetic Control Theory), and free radicals (The Free Radical Theory). Understanding of the nature that is not appropriate is believed by many community groups and even linked to problems that impede true religion in society. A true old age group the number is gradually increasing and this means increasing life expectancy. Actually, life expectancy can be scientifically programmed with faith. The development of science and technology so advanced in many fields, including health sciences and many other disciplines that support positive impact for the control of the aging process that increases a person's life expectancy. Pattern of life is very important role determining the aging process. This is evidenced by the report that 64% of deaths are caused by unhealthy lifestyles. Setting lifestyle that includes sleeping patterns, eating, working, break, and recreation, especially in determining the age of a person. Excess work or excess physical activity and lack of sleep will shorten the lifespan because penuaannya process occurs faster than their healthy life. This situation will reduce levels of some hormones and increases free radicals which will accelerate the aging process. Based on various research reports that turns the aging process can be slowed by setting lifestyle that consists of several elements of the lifestyle patterns such as sleep, work, eat, exercise and recreation. It is recommended that all people a healthy lifestyle as early as possible since the kids up for life.
MODEL AKTIVITAS PRAKTIKUM LAPANGAN BERBASIS ERGONOMI (APELERG) MEMPERBAIKI RESPON FISIOLOGIS TUBUH, MENURUNKAN KELELAHAN, DAN MENINGKATKAN KINERJA, DIBANDINGKAN DENGAN MODEL LAMA (APEL), PADA MAHASISWA FMIPA UNIMA Palilingan, Rolles; Manuaba, Adnyana; Adiputra, Nyoman; Pangkahila, Alex
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 3, No. 1 Januari 2009
Publisher : Udayana University

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Aktivitas praktikum lapangan merupakan kegiatan yang dilakukan sebagaiimplementasi kurikulum akademik di Jurusan Fisika FMIPA UNIMA. Sebagaiimplementasi kurikulum tersebut telah dibuat model aktivitas praktikum lapangan (modelAPeL) dan telah digunakan sejak tahun 2001. Namun model APeL ternyata menimbulkanrisiko yang merugikan bagi mahasiswa dilihat dari respon fisiologis dan kelelahansehingga mahasiswa belum dapat mencapai kinerja yang diharapkan. Untuk itu telahdiupayakan dengan penerapan pendekatan ergonomi total (PET) suatu model baru yaitumodel APeLErg. Untuk menguji keandalan model APeLErg dibandingkan dengan modelAPeL, telah dilakukan penelitian dengan hipotesis: model APeLErg, dibandingkan denganmodel APeL; memperbaiki respon fisiologis tubuh; menurunkan kelelahan; danmeningkatkan kinerja mahasiswa di daerah dataran rendah/panas dan di daerah datarantinggi/dingin. Penelitian ini dilakukan dalam dua tahap dengan menggunakan rancangansama subjek. Penelitian pada tahap pertama dilakukan di daerah panas denganmenggunakan 15 orang subjek sedangkan penelitian tahap kedua di daerah dinginmenggunakan 18 orang subjek. Hasil penelitian tahap I dan tahap II menunjukkan bahwaaktivitas dengan model APeLErg dapat: memperbaiki respon fisiologis mahasiswa secarasignifikan (p&lt;0,05); menurunkan rata-rata skor kelelahan umum secara signifikan(p&lt;0,05); meningkatkan kecepatan, kekonstanan dan ketelitian mahasiswa secarasignifikan (p&lt;0,05); dan meningkatkan kinerja mahasiswa secara signifikan (p&lt;0,05). Darihasil penelitian ini dapat disimpulkan bahwa model APeLErg dapat: memperbaiki responfisiologis mahasiswa; menurunkan tingkat kelelahan mahasiswa; dan meningkatkankinerja mahasiswa dalam melakukan aktivitas praktikum lapangan.
PELATIHAN FISIK BERLEBIH MENURUNKAN JUMLAH HEMATOPOIETIC STEM CELLS (HSCS) DIBANDINGKAN PELATIHAN FISIK SEIMBANG PADA TIKUS (RATTUS NORVEGICUS) WISTAR JANTAN ., Zenitalia; Pangkahila, Alex; Pangkahila, Wimpie; Siswanto, Ferbian M.
JURNAL BIOMEDIK : JBM Vol 10, No 1 (2018): JURNAL BIOMEDIK : JBM
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.10.1.2018.18996

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Abstract: This study was aimed to prove that balanced physical exercise increased mobilization of hematopoietic stem cells (HSCs) compared to excessive physical exercise in male Wistar rats (Rattus norvegicus). This was an experimental study with the randomized pretest-posttest control group design. Subjects were 24 male Wistar rats (Rattus norvegicus), 2.5-3 months old, weighing 180-200 g, healthy (active and did not show any anatomical abnormality), divided into two groups of 12 rats each. One group (P0) was treated with balanced physical exercise and the other group (P1) was treated with excessive physical exercise. Before (pretest) and 4 weeks after treatment (posttest), peripheral blood of 1 ml was drawn through medial canthus sinus orbitalis for examination of HSCs number in peripheral blood quantitatively. The results showed that the number of HSCs in the P0 group was increased from 1.60±0.70 x 106 cell/?l before treatment to 2.70±0.62 x 106 cells/?l after 4-week treatment (P <0.05). Meanwhile, in the P1 group, the number of HSCs was decreased from 1.74±0.68 x 106 cells/?l before treatment to 1.34±0.55 x 106 cells/?l after 4-week treatment (P <0.05). Conclusion: Excessive physical exercise decreased number of hematopoietic stem cells (HSCs) compared to balanced physical exercise in male Wistar rats (Rattus norvegicus).Keywords: balanced physical exercise, excessive physical exercise, hematopoietic stem cells (HSCs)Abstrak: Tujuan penelitian ini ialah untuk membuktikan bahwa pelatihan fisik berlebih menurunkan jumlah hematopoietic stem cells (HSCs) dibandingkan pelatihan fisik seimbang pada tikus (Rattus norvegicus) Wistar jantan. Jenis penelitian ini ialah eksperimental dengan randomized pre-post test control group design. Subyek penelitian ialah 24 ekor tikus Wistar (Rattus norvegicus) jantan, umur 2,5-3 bulan, berat badan 180-200 gr, sehat (aktif dan tidak menunjukkan abnormalitas anatomi) yang dibagi menjadi dua kelompok yaitu P0 dan P1, masing-masing berjumlah 12 ekor. Kelompok P0 diberikan pelatihan seimbang dan kelompok P1 diberi pelatihan fisik berlebih. Sebelum (pretest) dan 4 minggu setelah perlakuan (posttest), darah diambil sebanyak 1 ml melalui medial canthus sinus orbitalis untuk pemeriksaan kadar HSCs darah tepi secara kuantitatif. Hasil penelitian menunjukkan bahwa pada kelompok P0 terjadi peningkatan jumlah HSCs dari 1,60±0,70 x106 sel/?l pretest menjadi 2,70±0,62 x106 sel/?l posttest (P <0,05). Pada kelompok P1 terjadi penurunan jumlah HSCs dari 1,74±0,68 x106 sel/?l pretest menjadi 1,34±0,55 x106 sel/?l posttest (P <0,05). Simpulan: Pelatihan fisik berlebih menurunkan jumlah hematopoietic stem cells (HSCs) dibandingkan pelatihan fisik seimbang pada tikus (Rattus norvegicus) Wistar jantan.Kata kunci: pelatihan fisik seimbang, pelatihan fisik berlebih, hematopoietic stem cells (HSCs)
PEMBERIAN ALPHA LIPOIC ACID PER ORAL DAN LATIHAN FISIK INTENSITAS SEDANG MENURUNKAN BERAT BADAN DAN LEMAK ABODMINAL LEBIH BANYAK DARIPADA LATIHAN FISIK INTENSITAS SEDANG SAJA PADA TIKUS WISTAR JANTAN DENGAN OBESITAS Chandra, Aji B.; Pangkahila, Alex; Pangkahila, Wimpie
JURNAL BIOMEDIK : JBM Vol 9, No 1 (2017): JURNAL BIOMEDIK : JBM Suplemen
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/jbm.9.1.2017.15377

Abstract

Abstract: This study was aimed to prove that oral administration of ALA and moderate physical exercise decrease body weight and abdominal fat more than moderate physical exercise only in obese male Wistar rats. This was a true experimental study with a post-test only control group design. Subjects were 30 Wistar rats (Rattus norvegicus), male, healthy, aged 4-5 months, and obese with minimum weight of 250 g, divided into 3 groups, as follows: 1) P0, the control group with no treatment; 2) P1, given moderate physical exercise (swimming for 20 minutes/day, for 4 weeks); 3) P2, given moderate physical exercise and ALA per oral 15 mg/day for 4 weeks. The results showed that the average body weight after 4 weeks of treatment of P0 group was 279.10±5.84 g; of P1 group was 257.90±10.31 g; and of P2 group was 213.90±8.92 g (P < 0.01). The mean weight of subcutaneous abdominal fat of P0 group was 0.96±0.45 g; of P1 group was 0.63±0.31 g; and of P2 group was 0.40±0.23 g (P < 0.01 ). Moreover, the mean weight of visceral abdominal fat of P0 group was 1.23±0.37 g; of P1 group was 0.83±0.24 g; and of P2 group was 0.39±0.25 g (P < 0,01). Conclusion: Oral administration of ALA and moderate physical exercise decrease body weight, subcutaneous abdominal fat, and visceral abdominal fat more than moderate physical exercise only in obese male Wistar rats.Keywords: alpha lipoic acid, obesity, body weight, abdominal fatAbstrak: Penelitian ini bertujuan untuk membuktikan bahwa pemberian ALA per oral yang dikombinasi dengan latihan fisik intensitas sedang menurunkan berat badan, lemak subkutan abdominal, dan lemak viseral abdominal lebih banyak daripada latihan fisik intensitas sedang saja pada tikus Wistar jantan dengan obesitas. Jenis penelitian ialah eksperimental murni dengan post-test only control group design. Subjek penelitian ialah 30 ekor tikus putih (Rattus norvegicus) jantan, galur Wistar, sehat, usia 4-5 bulan, dan obes dengan berat badan minimal 250 g yang terbagi menjadi tiga kelompok masing-masing berjumlah 10 ekor tikus, yaitu: P0 (kelompok kontrol), tidak mendapat perlakuan apapun; P1, kelompok perlakuan 1 yang diberikan latihan fisik intensitas sedang (renang durasi 20 menit/hari selama 4 minggu); dan P2, kelompok perlakuan 2 yang diberikan latihan fisik intensitas sedang serta ALA per oral dengan dosis 15mg/hari selama 4 minggu. Hasil penelitian menunjukkan bahwa rerata berat badan setelah 4 minggu perlakuan pada kelompok P0 ialah 279,10±5,84 gr; pada kelompok P1 257,90±10,31 gr; dan pada kelompok P2 213,90±8,92 gr (P < 0,01). Rerata berat lemak subkutan abdominal pada kelompok P0 ialah 0,96±0,45 gr; pada kelompok P1 0,63±0,31 gr; dan pada kelompok P2 0,40±0,23 gr (P < 0,01). Selain itu, rerata berat lemak viseral abdominal pada kelompok P0 ialah 1,23±0,37 gr; pada kelompok P1 0,83±0,24 gr; dan pada kelompok P2 0,39±0,25 gr (P < 0,01). Simpulan: Pemberian ALA per oral dengan latihan fisik intensitas sedang dapat menurunkan berat badan, lemak subkutan abdominal, dan lemak viseral abdominal lebih banyak daripada latihan fisik intensitas sedang saja pada tikus Wistar jantan dengan obesitasKata kunci: alpha lipoic acid, obesitas, berat badan, lemak abdominal
PELATIHAN FISIK SEIMBANG MENINGKATKAN AKTIVITAS STEM CELL ENDOGEN UNTUK ANTI PENUAAN Milas Siswanto, Ferbian; Pangkahila, Alex
Sport and Fitness Journal Volume 2, No.1, 2014
Publisher : Program Studi Magister Fisiologi Keolahragaan, Fakultas Kedokteran, Universitas Udayana

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Abstract

Human life expectancy increasing progressively declines with technological developments and poor lifestyle. The cause of death due to an unhealthy lifestyle among other physical activity that is not in accordance with scientific principles accelerates the aging process. The development of the science of Anti - Aging Medicine is expected to improve human welfare through increased life expectancy. Several attempts have been made, both in research and clinical reports, to find the factors of aging that can do prevention and control. These efforts are expected to be a reference to slow down the aging process and preventing the aging occur. One of the efforts that have been made in various countries is the use of stem cells. The utilization of stem cells is a breakthrough in the field of medicine to address degenerative diseases and slow down the aging process. The ability of proliferation, differentiation and self- renewal of stem cells can be used to replace the cells, tissues, and organs damaged by the aging process. The characters and the unique benefits of this increase the number of stem cell field research. One area of ??research that is related to the formation of the stem cell is physical exercise factor. The benefits of physical training on endogenous stem cells give new hope in the field of anti - aging medicine. Regular physical training in accordance with scientific principles (exercise physiology), is expected to prevent anti-aging through activation of endogenous stem cells in the body naturally.