Adi Prayitno
Medical School of Sebelas Maret University, Surakarta

Published : 19 Documents
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Incidence of HPV Infection in Oral Squamous Cell Carcinoma and Its Association with the Presence of p53 & c-myc Mutation : A Case Control Study in Muwardi Hospital Surakarta Prayitno, Adi; Rukmo, Mandojo; Mudigdo, Ambar; Dalono, Dalono; Asnar, Elyana; Rahayu, Retno Puji; Purwanto, Joko Agus; Puspaningsih, Ni Nyoman Tri; Kuntoro, Kuntoro; Harjanto, Harjanto; Putra, Suhartono Taat
Journal of Dentistry Indonesia Vol 17, No 2 (2010): August
Publisher : Faculty of Dentistry, University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (487.302 KB) | DOI: 10.14693/jdi.v17i2.44

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Introduction: Annual incidence rates for oral and pharyngeal cancer are estimated at 25 cases per 100,000 in developing countries. Human papilloma virus (HPV) was implicated in pathogenesis of Cancer. The mutations of p53 and c-myc are found 50% in cancer. Objective: Aims of this research were to know the incidence of OSSC patient which realized HPV infection without p53 and c-myc gene mutation. Materials and Methods: Tissue biopsy frozen sections were taken from BOSC (Benign Oral Squamous Cell) and OSCC (Oral Squamous Cell Carcinoma) patients collected from Oral and Dental Departement of dr Muwardi Distric Hospital in Surakarta from January 2007 to January 2008. To amplify L1-HPV gene for fixed the HPV stressor. To amplify p53 and c-myc genes, continued with SSCP (Single Strand Conformational Polymorphisme) analysis and followed with measurement using densitometer, to see mutation existence. The collected data were analyzed with Chi Square. Results: BOSC patient identified 23% with HPV infections and OSCC patient identified 73% with HPV infections. Hundred percent BOSC patient with HPV infection without mutation in p53 gene and c-myc gene, 81% OSCC patient with HPV infection without mutation in p53 gene and 91% OSCC patient with HPV infection without mutation in c-myc gene. Chi  square analysis showed significant difference between BOSC and OSCC patients with HPV infection without mutation in p53 and c-myc gene. Conclusion: HPV is a factor for pathogenesis of OSCC.DOI: 10.14693/jdi.v17i2.44
The Role of Heat Shock Proteins in Pathogenesis of Oral Squamous Cell Carcinoma Prayitno, Adi; Rukmo, Mandojo; Mudigdo, Ambar; Dalono, J. B.; Asnar, Elyana; Rahayu, Retno Puji; Purwanto, Joko Agus; Puspaningsih, Ni Nyoman Tri; Kuntoro, Kuntoro; Harjanto, Harjanto J. M.; Putra, Suhartono Taat
Journal of Dentistry Indonesia Vol 16, No 2 (2009): August
Publisher : Faculty of Dentistry, University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2754.761 KB) | DOI: 10.14693/jdi.v16i2.91

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Cell in the distress situation, denaturation of proteins may occur, and may also respond by expressing stress proteins. However, such homeostasis effort does not always succeed and even may lead to disease, including cancer. In distress situation also ensue much protein misfolding. Objective: This research were to explain the role of heat shock protein 40 (Hsp40) and Hsp70 in pathogenesis of occurred oral squamous cell carcinoma (OSCC) patient which realized human papilloma virus (HPV) infection. Material and Method: Tissue biopsy frozen section were taken from BOSC and OSCC patients was cut into three part. Parrafin blocks were made from cutting I, which was subsequently stains with HE to ascertain the type of neoplasm. Cutting II was subjected to DNA isolation. The DNA isolation results were subjected to PCR to amplify L1-HPV gene for fixed the HPV stressoor. Protein isolation was treated from Cutting III, folloewd with Blottdot test by using antibody monoclonal anti Hsp40 and Hsp70 and continued with measurement using densitometer to find the concentration of Hsp40 and Hsp70. The collected data were analyzed with F Test (Manova) and discriminant analysis. Result: This experiment showed the differences in concentration of Hsp40 (p<=0,070) and Hsp70 (p<=0,006) between beningn oral squamous cell (BOSC) and OSCC patients which realized HPV infection. Conclusion: This experiment proved that OSCC patients which realized HPV infection indicated an up regulated of Hsp70 concentration, so that there was occurs misfolding of the proteins cell. The misfolding was ensue obstacle of apoptosis and to raise cell proliferation which to storm carcinogenesis. An up regulated of Hsp40 was role as co-chaperone.DOI: 10.14693/jdi.v16i2.91 
Pengaruh Media Puzzle Tumpeng Gizi Seimbang Terhadap Pengetahuan Gizi dan Pola Makan Anak Taman Kanak – Kanak Thamrin, Hermawati; Santoso, Santoso; Prayitno, Adi
Jurnal Gizi dan Kesehatan Vol 1, No 1 (2014)
Publisher : Program Studi Ilmu Gizi Pascasarjana Universitas Sebelas Maret

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ABSTRAK Latar Belakang: Pendidikan gizi sangat diperlukan untuk meningkatkan pengetahuan gizi murid, membentuk sikap positif terhadap makanan bergizi dalam rangka membentuk kebiasaan makan yang baik. Kurang gizi pada anak TK umumnya disebabkan karena rendahnya pengetahuan gizi dan pola makan anak yang tidak teratur. Tujuan penelitian ini adalah untuk mengetahui  pengetahuan gizi dan pola makan anak TK sebelum dan sesudah dilaksanakan metode pendidikan gizi menggunakan media Tumpeng Gizi Seimbang, Untuk mengetahui apakah ada pengaruh dalam pelaksanaan metode pendidikan gizi menggunakan media Puzzle Tumpeng Gizi Seimbang terhadap peningkatan pengetahuan gizi dan pola makananak TK.Metode: penelitian ini menggunakan metode eksperimen, pendekatan cross sectionaldenganpre –eksperimental design bentuk one group pre –post. Populasi penelitian ini adalah semua murid TK Islam Bakti I Karanganyar tahun ajaran 2012/2013 dengan jumlah sampel 30 anak. Teknik pengumpulan data dengan kuesioner pengetahuan gizi dan formulir food recall pola makan. Data yang terkumpul dianalisis dengan One Way Anova dan dilanjutkan Regresi Linier.Hasil: Penelitian pengetahuan gizi anak TK, One Way Anova menunjukkan adanya peningkatan secara signifikan dari kategori rendah (pvalue = 0.004) menjadi baik (pvalue = 0.000) dan hasil analisis Regresi menunjukkannilai pvalue = 0.002atau< 0.05.  Hasil penelitian pola makan dengan analisis One Way Anova menunjukkan adanya peningkatan secara signifikan(pvalue energi, protein dan vitamin C = 0.000) dan hasil analisis Regresi pola makan (energi nilai pvalue = 0.002, protein nilai pvalue = 0.044 dan vitamin C nilai pvalue = 0.010) atau nilai pvalue< 0.05. Sehingga ada pengaruh metode pendidikan gizi menggunakan media Puzzle Tumpeng Gizi Seimbang terhadap pengetahuan gizi dan pola makan anak TK.Kesimpulan: Pendidikan gizi dilaksanakan secara kontinyu dan berulang – ulang maka pengetahuan gizi dan pola makan (kecukupan zat gizi ; energi, protein, lemak dan vitamin C) anak TK akan semakin meningkat. Kata Kunci : Pendidikan Gizi, Pengetahuan Gizi, Pola Makan , Anak TK
Pengaruh Penyuluhan Pola Asuh Terhadap Peningkatan Status Gizi Anak Balita Fadhialh, Tri Marta; Suparyatmo, JB.; Prayitno, Adi
Jurnal Gizi dan Kesehatan Vol 1, No 2 (2014)
Publisher : Program Studi Ilmu Gizi Pascasarjana Universitas Sebelas Maret

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ABSTRAK Latar Belakang: Penyuluhan pola asuh merupakan suatu pendekatan edukatif yang dilakukan dengan cara memberikan perhatian, menyampaikan pesan, mengajak beraktifitas dan memberikan pemikiran/solusi. Kekurangan gizi pada anak usia dibawah lima tahun (balita) antara lain disebabkan oleh pola asuh yang jelek, sehingga terjadi penurunan status gizi anak tersebut. Penelitian ini bertujuan untuk menganalisis pengaruh penyuluhan pola asuh (pemberian makanan sehat, praktek kebersihan dan sanitasi lingkungan serta perawatan saat sakit) terhadap peningkatan status gizi balita.Metode: Jenis penelitian ini adalah Pre-experimental dengan rancangan One group pre-test and post-test desain. Sampel terdiri dari balita dengan usia hingga 60 bulan (5 tahun) dengan status gizi kurang yang tinggal di Desa Bangsri dan Karang, Kecamatan Karangpandan, Kabupaten Karanganyar 1 April hingga Agustus 2013. Teknik pengumpulan data menggunakan kuestioner tentang pola asuh (pemberian makanan sehat, praktek kebersihan dan sanitasi lingkungan, perawatan saat sakit) dan pengukuran BB/TB. Data yang terkumpul dianalisis dengan uji Paired T-test dan uji Bivariate Correlation.Hasil: Ada 80 balita dikumpulkan. Sebelum konseling tercatat bahwa pemberian makanan sehat dengan 52,40 poin dan sesudah konseling dengan 89,8 poin. Praktek kebersihan dan sanitasi lingkungan dengan 62,73 poin (sebelum) dan 85.42 poin (sesudah). Perawatan saat sakit dengan 55.27 poin (sebelum) dan 82,84 poin (sesudah). Dan nilai BB / TB dengan 1,30 poin (sebelum) dan 0,43 poin (sesudah). Ada perbedaan yang signifikan antara sebelum dan sesudah penyuluhan tentang pemberian makanan sehat, praktek kebersihan dan sanitasi lingkungan, serta perawatan saat sakit (p = 0,001). Ada pengaruh yang signifikan antara penyuluhan pola asuh (pemberian makanan sehat, praktek kebersihan dan sanitasi lingkungan, serta perawatan saat sakit) dengan peningkatan status gizi balita (p = 0.008).Kesimpulan: Kesimpulan penelitian ini adalah semakin sering dilakukan penyuluhan pola asuh (pola pemberian makanan sehat, praktek kebersihan dan sanitasi lingkungan, dan perawatan saat sakit) semakin meningkat status gizi balita. Kata Kunci : Penyuluhan, Pola Asuh, Status Gizi, Balita
PENGARUH PEMBERIAN EKSTRAK TEPUNG DAUN KELOR (Moringa oleifera) TERHADAP ROS (KADAR MDA) DAN GAMBARAN HISTOPATOLOGI JARINGAN PARU PADA TIKUS WISTAR YANG DIINHALASI ASAP ROKOK Susilowati, Titik; Suradi, Suradi; Prayitno, Adi
Jurnal Gizi dan Kesehatan Vol 2, No 2 (2015)
Publisher : Program Studi Ilmu Gizi Pascasarjana Universitas Sebelas Maret

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ABSTRAK Latar belakang : Rokok mengandung berbagai bahan kimia antara lain nikotin, tar, dan karbon monoksida sedangkan asap rokok mengandung molekul oksidan antara lain superoksida, hidrogen peroksida, hidroksil dan peroksil. Paru menjadi organ yang paling sering terpapar radikal bebas luar terutama asap rokok sehingga perlu ditambahkan antioksidan dari luar untuk menangkalnya. Zat yang dapat menetralkan radikal bebas adalah antioksidan yang dapat diperoleh dari daun kelor dan memiliki potensi suplemen antioksidan. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak tepung daun kelor (Moringa oleifera) pada tikus Wistar yang diinhalasi asap rokok. Metode: Penelitian ekperimental laboratorik dengan Pre and Post Randomized Controled Group Design. Sampel terdiri dari 30 ekor tikus Wistar jantan yang dibagi secara simple random sampling menjadi 5 kelompok. Kelompok KN diberi diet standar dan tidak diinhalasi asap rokok. Kelompok KP diberi diet standar dan diinhalasi asap rokok 3 batang per hari tanpa diberi ekstrak tepung daun kelor, kelompok P1, P2, P3 diberi diet standar dan ekstrak tepung daun kelor dengan dosis secara bertingkat yaitu 400 mg/200 gr BB/hari, 600 mg/ 200 gr/hari dan 800 mg/200 gr/hari setelah diinhalasi asap rokok 3 batang per hari. Perlakuan diberikan selama 14 hari. Hari ke-15 semua sampel diterminasi untuk dilakukan pembuatan preparat paru dan pemeriksaan gambaran histopatologi jaringan paru. Uji analisis menggunakan One Way Anova dan uji Post Hoc Test serta uji Regresi. Hasil: Hasil uji One Way Anova untuk kadar MDA, jumlah sel netrofil, limfosit dan eritrosit didapatkan perbedaan yang bermakna antara KN, KP, P1, P2, P3. Hasil uji Kruskall Wallis untuk gambaran histopatologi jaringan paru didapatkan perbedaan yang bermakna antara KN, KP, P1, P2, P3. Hasil uji Post Hoc Test untuk gambaran histopatologi jaringan paru tidak bermakna pada KN dengan P3. Hasil uji Regresi pengaruh pemberian ekstrak tepung daun kelor terhadap ROS (Kadar MDA) menunjukkan bahwa ada hubungan antara peningkatan dosis ekstrak tepung daun kelor yang diberikan dengan Kadar MDA (Y’ = 11,400 - 0,012X + ԑ). Hasil uji Regresi pengaruh pemberian ekstrak tepung daun kelor terhadap gambaran histopatologi jaringan paru menunjukkan bahwa ada hubungan antara peningkatan dosis ekstrak tepung daun kelor yang diberikan dengan peningkatan efek proteksi terhadap histopatologi jaringan paru (Y’ = 9,481 - 0,010X + ԑ). Kesimpulan: Terdapat pengaruh pemberian dosis ekstrak tepung daun kelor terhadap gambaran histopatologi jaringan paru pada tikus Wistar yang diinhalasi asap rokok.  Kata kunci: Asap rokok, daun kelor, radikal bebas, antioksidan, paru
Multilevel Analysis on the Factors Associated with Low Birth Weight in Temanggung, Central Java Khayati, Yulia Nur; Prayitno, Adi; Poncorini, Eti
Journal of Maternal and Child Health Vol 1, No 1 (2016)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Infants with low birth weight or LBW is one of the risk factors for infant mortality. Complications LBW actually can be prevented and dealt with, but is constrained by access to health care, socio-economic circumstances, a referral system that has not gone well, delays in early detection and awareness of parents to seek medical help. By looking at the number of deaths caused by LBW remains high, and research on the causes of LBW widely used partial analysis, and have not been analyzed in stages, the researchers conducted this research with multilevel analysis.Subjects and Method: This was an observational studt with case control design. A total sample of 120 infants were selected by fixed disease sampling with a ratio of 1: 2 between cases and controls. Data were analyzed using multiple logistic regression.Results: There are three variables at the individual level were significantly associated with LBW and was statistically significant can among others, mother’s education (OR= 0.19; 95% CI= 0:07 to 0.53; p= 0.001), history of ANC t (OR= 7.76; 95% CI= 2.18 to 27.62; p= 0.002) and the nutritional mother status (OR= 5.61; 95% CI= 0.21 to 0.79; p= 0.008) and the variables that are not statistically significant is the mother’s age and family income, and there are  no contextual role within house with wellness facilities with LBW expressed by ICC < 0.001.Conclusion: The influence of maternal education, a history of the ANC examination and nutritional status of mothers with LBW and there is no contextual role of distance between home and health care facilities with LBW. This study suggests to health professional to improve the coverage of the ANC.Keywords: multilevel analysis, factor low birth weightCorrespondence: Yulia Nur Khayati. School of Health and sciences, STIKes Ngudi Waluyo, Ungaran, Indonesia. Email: yulia.farras@gmail.com.Journal of Maternal and Child Health (2016), 1(1): 7-12https://doi.org/10.26911/thejmch.2016.01.01.02
UJI VALIDITAS, REALIBILITAS HASIL PENGUKURAN BERAT BADAN MENGGUNAKAN RUMUS JUNG DENGAN TIMBANGAN ELEKTRONIK PADA PASIEN STROKE LANJUT USIA Jabar, Laode Abdul; Prayitno, Adi; Pancarini, Ety
Jurnal Kesehatan Kusuma Husada Vol. 9 No. 2, Juli 2018
Publisher : STIKes Kusuma Husada Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (445.075 KB) | DOI: 10.34035/jk.v9i2.277

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Pasien stroke akut seringkali tidak memiliki waktu dan sarana yang memadai untuk melakukan penimbangan berat badan pasien yang sebenarnya (aktual). Untuk pasien stroke tirah baring (bed rest), terpaksa harus di ukur menggunakan tempat tidur (hospital bed) khusus yang dilengkapi dengan timbangan berat badan elektronik. Akan tetapi, harganya sangat mahal dan tidak dimiliki oleh semua rumah sakit. Oleh karena itu, diperlukan instrumen yang bisa mengukur secara akurat dan tersedia secara luas di rumah sakit.Tujuan penelitian ini adalah untuk mengetahui validitas dan realibilitas hasil pengukuran berat badan menggunakan rumus Jung dengan timbangan elektronik pada pasien stroke lanjut usia. Jenis penelitian ini adalah observasional dengan desain cross sectional. Penelitian dilaksanakan pada bulan Mei 2017 sebanyak 94 pasien stroke rawat jalan di poliklinik Neuro RSUD dr. Moewardi Surakarta dilakukan pengukuran berat badan aktual menggunakan timbangan elektronik yang sebelumnya telah dikalibrasi ke terdekat 0,1 kg. Selanjutnya, dilakukan pengukuran lingkar lengan atas dan tinggi lutut yang kemudian dimasukkan kedalam rumus estimasi berat badan lansia Jung. Hasil penelitian ini adalah Rumus jung memiliki validititas yang baik terhadap timbangan elektronik pada pengkuruan berat badan pasien stroke lansia yang dapat dilihat pada nilai AUC sebesar 88,91% pada taraf signifikansi (a = 0,05) yaitu p-value = 0,000 &lt; 0,05. Rumus jung terbukti realible/handal digunakan untuk pengkuruan berat badan pada pasien stroke lansia. Hal ini ditunjukkan dengan nilai AUC &gt; 0,5 sebesar 12,084 (sig) p= 0,000 lebih kecil pada taraf signifikan a = 5%. Kesimpulan penelitian ini adalah Rumus Jung baik digunakan pada pengukuran berat badan pasien stroke. Acute stroke patients often do not have sufficient time and facilities for actual patient weight balancing (actual). For bed rest stroke patients, forced to be measured using a bed (hospital bed) special equipped with electronic weighing scales. However, the price is very expensive and is not owned by all hospitals. Therefore, an instrument that can measure accurately and widely available in the hospital is required. Objective of this study is to determine the validity and reliability of the results of weight measurements using Jung's formula with electronic scales in elderly stroke patients. The type of this study was observational with cross sectional design. This studi was conducted During May 2017 as many as 94 outpatient stroke patients in polyclinic Neuro RSUD dr. Moewardi Surakarta conducted actual weight measurement using electronic scales that had previously been calibrated to the nearest 0.1 kg. Furthermore, the measurement of the upper arm circumference and knee height is then incorporated into the formula of Jung's elderly weight estimate. Result this study the jung formula has good validity to the electronic scales in aging body weight of elderly stroke patients which can be seen in AUC value of 88,91% at significance level (a = 0,05) that is p-value = 0,000 &lt;0,05. The proven realible / reliable junior formula is used for weight gain in elderly stroke patients. This is indicated by the value of AUC&gt; 0.5 for 12.084 (sig) p = 0.000 smaller at significant level a = 5%. Conclusionthis study is Jung's formula is good for measuring the weight of stroke patients.
REDUCING PRIMARY DYSMENORRHEA AMONG ADOLESCENT GIRLS WITH MUNG BEAN EXTRACT DRINKS AND STRETCHING Septiani, Baiq Dewi Sukma; Prayitno, Adi; Sugiarto, Sugiarto
International Journal of Public Health Science (IJPHS) Vol 8, No 1: March 2019
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (379.669 KB) | DOI: 10.11591/ijphs.v8i1.14852

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Primary dysmenorrhea is pain during menstruation period due to high levels of prostaglandins, especially prostaglandin F2? in epithelial cells. MungBean Extract Drinks contain several nutrients including vitamin C, calcium, carbohydrates and flavonoids as anti-depressants and anti-inflammatory agent. Stretching is a relaxation technique that can helps relieve menstrual pain in the abdominal part by increasing the production of endorphins which function as neurotransmitters. To determine the effect of Mung Bean ExtractDrinks and Stretching on primary dysmenorrhea (primary menstrual pain) in adolescent girls stressed. This type of open-label non-randomized controlled trial used 87female adolescents who experienced primary menstrual pain with moderate and severe stress levels from two Islamic boarding schools in Mataram City, West Nusa Tenggara, Indonesia, which were divided into 3 groups, one group as the control and two groups as the experiment. The experiment of 29people with pre and post-test. Mung bean extract drinks were given 250ml/day, otherwise stretching was given 1x/day for 7days before menstruation. Control and experimental group was observed for 1 month. Measurement of menstrual pain scale using the Numeric Rating Scale (NRS) assessment sheet. Data analysis uses T-test. The mean primary menstrual pain in adolescents for MungBean Extract Drinks with moderate stress levels was 1.31±1.32 and the difference before and after mung bean extract drinks experience is significant at p=0.004 while at severe stress levels was 1.69±1.54 and the difference between before and after mung bean extract drinks experience is significant at p=0.001. The mean primary menstrual pain in adolescents for stretching experience with moderate stress levels was 2.50±1.93 and the difference before and after stretching experience is significant at p=0.008 while the severe stress level was 2.05±1.80 and the difference before and after stretching experience is significant at p?0.001. The multivariate test with linear regression revealed that mung bean extract drinks contributed y= (-)138X1+4.897(p=0.001) and related stretching contributed y= (-)2.517X1+6.276(p=0.001). MungBean ExtractDrinks and Stretching will affect to the reduction of primary dysmenorrhea in adolescent girls both at moderate and severe stress levels
Association betweenMaternal Age at Pregnancy, Socioeconomic Status, Physical Environment, Prenatal, Perinatal, Postnatal History, and the Risk of Mental Retardation Nurochim, Erna; Indarto, Dono; Prayitno, Adi
Journal of Maternal and Child Health Vol 1, No 2 (2016)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Mental retardation (MR) is a serious public health problem for an country. The prevalence of mental retardation in Indonesia was estimated at 1-3% of the population. About 0.1% of whichneed treatment and guidance the whole life. This study aimed to determine the association between maternal age at pregnancy, socioeconomic status, physical environment, prenatal, perinatal, postnatal history, and mental retardation.Subject and methods: This was an analytic observational study with case control design. This study was conducted in Pare, Kediri, East Java, Indonesia,from October to December 2016. A total 105 study subjects, consisting of 35 MR cases and 70 controls were selected for this study by fixed disease sampling. The independent variables were maternal age at pregnancy, socioeconomic status, physical environment, prenatal, perinatal, and postnatal history. The dependent variable was mental retardation. The data were collected by questionnaire and analyzed by logistic regression model.Results: Maternal age ≥35 years at pregnancy was associated with an increased risk of MR, and it was statistically significant The result showed that mother’s age while pregnant (OR=10.18; 95%CI=2.77 to 37.39; p<0.001). High socioeconomic status (OR=0.23;95%CI=0.07 to 0.81; p=0.022), good physical environment (OR=0.13; 95%CI=0.04 to 0.45; p=<0.001), good prenatal history (OR=0.24;95%CI=0.07 to 0.82; p=0.022), good perinatal history (OR=0.45;95%CI=0.15 to 1.40; p=0.168), good postnatal (OR=0.43;95%CI=0.14 to 1.35; p=0.148), were associated with a decreased risk of MR. Nagelkerke R2=53.8% for this model.Conclusion: Maternal age ≥35 years at pregnancy increases the risk of MR. High socioeconomic status, good physical environment, good prenatal, perinatal, and postnatal history, decrease the risk of MR.Keywords: mental retardation, maternal age at pregnancy, socioeconomic status, environment, pregnancy history.Correspondence: Erna Nurochim. Masters Program in Public Health, Sebelas Maret University, Surakarta.Journal of Maternal and Child Health (2016), 1(2): 119-130https://doi.org/10.26911/thejmch.2016.01.02.07
Hubungan Konsumsi Fast Food dan Soft Drink dengan Kejadian Obesitas pada Remaja Usia 15-17 Tahun Barokah, Falah Indriawati; Mudigdo, Ambar; Prayitno, Adi
Jurnal Gizi dan Kesehatan Vol 1, No 1 (2014)
Publisher : Program Studi Ilmu Gizi Pascasarjana Universitas Sebelas Maret

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Latar Belakang : Fast food dan soft drink keduanya banyak mengandung gula, terutama gula buatan. Gula buatan terbukti tidak baik untuk kesehatan karena dapat menyebabkan obesitas jika dikonsumsi terus menerus. Sehingga penulis tertarik untuk mengetahui hubungan konsumsi fast food dan soft drink dengan kejadian obesitas pada remaja umur 15-17 tahun.Metode : Penelitian ini menggunakan rancangan observasional analitik dengan pendekatan cross sectional. Populasi pada penelitian ini adalah seluruh siswa kelas X dan XI SMA Muhammadiyah 3 Jakarta dengan jumlah sampel 105 siswa. Teknik pengumpulan data dengan food frequency questionnaire dan formulir food recall. Data yang terkumpul dianalisis dengan Regresi Linear Berganda.Hasil : Terdapat hubungan yang signifikan antara konsumsi fast food dengan kejadian obesitas remaja (β = 0,111) dan (p = &lt;0,001) dengan persamaan (Y = 0,1X). Terdapat hubungan yang signifikan antara selera konsumsi soft drink dengan kejadian obesitas remaja (β = 0,05) dan (p = 0,018) dengan persamaan (Y = 0,05X). Semakin banyak remaja mengkonsumsi soft drink, dan fast food maka semakin tinggi risiko kejadian obesitas pada remaja umur 15-17 tahun. Kadar kortisol rata-rata pada siswa obesitas (A) dan non obesitas (B) berbeda tidak signifikan (A:B = 9,47:9,76).Kesimpulan : Sehingga kesimpulan yang didapat pada penelitian ini adalah bahwa fast food dan soft drink keduanya banyak mengandung karbohidrat. Selanjutnya kelebihan karbohidrat akan diubah menjadi asam lemak oleh hormon kortisol yang ditandai dengan terjadinya obesitas. Keywords : Fast Food, Soft Drink, Obesitas