Arsita Eka Rini
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Faktor Risiko Air Ketuban Keruh Terhadap Kejadian Sepsis Awitan Dini pada Bayi Baru Lahir Kosim, Muhammad Sholeh; Rini, Arsita Eka; Suromo, Lisyani B
Sari Pediatri Vol 12, No 3 (2010)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp12.3.2010.135-41

Abstract

Latar belakang. Sepsis neonatorum merupakan masalah utama dan penyebab kematian terbanyak di negaraberkembang. Air ketuban keruh bercampur mekonium merupakan salah satu faktor risiko sepsis bayi barulahir dan terjadi pada sekitar 10%-20% seluruh kelahiran.Tujuan. Membuktikan air ketuban keruh merupakan faktor risiko kejadian sepsis awitan dini pada bayibaru lahir.Metode. Penelitian menggunakan desain kohort. Subjek adalah bayi dengan kriteria inklusi dan lahirdengan air ketuban keruh bercampur mekonium di RS Dr. Kariadi bulan Oktober 2009 – Maret 2010.Bayi lahir dengan air ketuban jernih sebagai kontrol. Air ketuban diambil pada hari ke-1, biakan darah,dan pemeriksaan darah tepi pada hari ke-5. Analisis statistik menggunakan chi square, Mann Whitney, danrisiko relatif (95% confidence interval).Hasil. Subjek 70 bayi lahir dengan air ketuban keruh berisiko 10x lebih tinggi mengalami sepsis (95%CI=1,3-74,0; p=0,003). Risiko relatif adanya kuman pengecatan Gram (+) di dalam air ketuban terhadapterjadinya sepsis 1,4 (95%CI=0,3-6,8;p=0,6) dan adanya kedua jenis kuman Gram (+) dan (-) 2,4 (95%CI=0,7-7,7; p=0,2). Risiko relatif bayi dengan air ketuban mengandung biakan E coli mempunyai risikokejadian sepsis 3,8 (95%CI=0,8-17,0;p=0,057) dan biakan non E coli 2,4 (95% CI=0,4-13,1; p=0,4).Faktor risiko lain adalah adanya kuman dalam biakan darah, berisiko 6,3 x lebih tinggi mengalami sepsis(95% CI=1,4-29,3; p=0,02).Kesimpulan. Air ketuban keruh merupakan faktor risiko terjadinya sepsis bayi baru lahir awitan dini. Jeniskuman pengecatan Gram dan biakan kuman dalam air ketuban bukan merupakan faktor risiko terjadinyasepsis awitan dini
Meconium-stained amniotic fluid viscosity and chest x-ray findings Rajagukguk, Ricki; Kosim, Muhammad Sholeh; Rini, Arsita Eka; Mardiana, Mardiana
Paediatrica Indonesiana Vol 52 No 6 (2012): November 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (140.084 KB) | DOI: 10.14238/pi52.6.2012.336-40

Abstract

Background Approximately 8-15% of all infants are born withevidence of meconium-stained amniotic fluid (MSAF). Manyof these infants rapidly initiate a good respiratory response andare othenvise vigorous. Other infants present v.ith a variety ofrespiratory distress. Chest x-ray imaging is the main test done toevaluate respiratory distress in order to differentiate pulmonaryand extrapulmonary etiologies.Objective To determine the relationship between viscosity ofMSAF and chest x-ray imaging results.Methods This cross-sectional study was held from January to June2011, as a continuation of a previous study from August 2009 toMay 2010 at Kariadi Hospital, Semarang, Indonesia. Data wastaken from medical records of babies who were born v.ith MSAF.MSAF viscosity measurements by the investigator and laboratorytechnician were assessed by Kappa test in the previous study witha result of 0.7 4. X-ray findings were determined by the radiologiston duty at that time. Chi square and logistic regressiontests wereused for statistical analysis.Results There were 48 subjects consisting of 26 males and 22females. Chest x-ray imaging results showed normal findings in33.3% of subjects, pneumonia in 58.3% of subjects and meconiumaspiration syndrome in 8.3% of subjects. Thick viscosity MSAFwas significantly correlated to abnormal x-ray imaging (RR= 2.046;P=0.004; 95%CI 1.12 t03.72).Conclusion Thick MSAF viscosity significantly increased therisk of abnormal chest x-ray findings. [Paediatr Indones.2012;52:336-40].