Nelly Rosdiana
University of South Sumatera, Medan

Published : 23 Documents
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Quality of life assessment of children with thalassemia Wahyuni, Masyitah Sri; Ali, Muhammad; Rosdiana, Nelly; Lubis, Bidasari
Paediatrica Indonesiana Vol 51 No 3 (2011): May 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.968 KB) | DOI: 10.14238/pi51.3.2011.163-9

Abstract

Background Thalassemia is a chronic disease that is becoming a major health problem in the world, including the Mediterranean, as well as Malaysia, Thailand and Indonesia. This condition clearly affects the patient's quality of life, because of the condition itself andthe effects of treatment. Assessment is needed to detennine actions to be taken to improve the quality of life in thalassemic children.Objective To assess the differences in quality of life of thalassemic children compared to their normal siblings.Methods We perfonned a cross????sectional study from May 2010 until June 2010 in H. Adam Malik Hospital, Medan and the home of a member of the North Sumatra Chapter of the Association of Parents of Thalassemia Sufferers (perhimpunan Orangtua PenderitaTalasemia Indonesia, POPTI). Thalassemic children aged 5-18 years and their age and gender????adjusted siblings were divided into two groups: case group and control group. Parents and children were asked to fill the PedsQL (Pediatric Quality of life Inventory)version 4.0 questionnaire to assess their quality of life.Results There were 59 children in each group. The assessments of four quality of life domains in the thalassemic group vs the control group showed the folloMng: physical function 53.1 vs 71.5 (95% CI -21.41 to -15.26, P????O.OOOI), emotional function 50.9 vs 62.9 (95% CI -16.82 to -7 .41, P????O.OOO 1), social function 62.5 vs 72.8 (95% CI-13.50 to -7.01, P????O.OOOI) and school function 36.2 vs 56.0 (95% CI -22.95 to -16.71, P????O.OOOI). Total scores were 50.9 vs 66.1 (95% CI -18.20to -13.12, P????O.OOOI). School function was the most affected parameter studied, with thalassemic children scoring lower than the control group.Conclusion There were significant decreases in the quality of life parameters in the thalassemic group compared to the control group. Thalassemic children have poorer quality oflife compared to their nonnal siblings, Mth school function being the mostaffected domain. 
Tata Laksana Ekstravasasi Karena Pemakaian Kemoterapi Rosdiana, Nelly
Indonesian Journal of Cancer Vol 3, No 2 (2009): Apr - Jun 2009
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.045 KB) | DOI: 10.33371/ijoc.v3i2.105

Abstract

Ekstravasasi merupakan suatu keadaan yang bisa muncul pada pasien kanker yang mendapat kemoterapi, yang menimbulkan rasa sakit dan eritema, ulkus, serta kerusakan jaringan. Beberapa obat sitostatika dapat bersifat vesicant, iritan, dan nonvesicant. Tata laksana ditentukan dari stadium ekstravasasi, banyaknya cairan yang terpapar, dan ketersediaan antidotum yang spesifik.Kata kunci: ekstravasasi, kemoterapi, tata laksana.
WAIST CIRCUMFERENCE, BODY MASS INDEX, AND SKINFOLD THICKNESS AS POTENTIAL RISK FACTORS FOR HIGH BLOOD PRESSURE IN ADOLESCENTS Dewi, Roslina; ramayati, rafita; Rosdiana, Nelly; Ramayani, Oke Rina; Siregar, Rosmayanti; Siregar, Beatrix
Paediatrica Indonesiana Vol 59 No 2 (2019): March 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.132 KB) | DOI: 10.14238/pi59.2.2019.79-86

Abstract

Background The prevalence of hypertension in children and adolescents has increased with the rising obesity epidemic. Recent studies have found that prevalence of hypertension was higher in obese children or adolescents than in the normal weight ones. Anthropometric measurements such as body mass index (BMI), waist circumference, and skinfold thickness have been used as criteria to determine obesity in children and adolescents. Increased waist circumference has been most closely related to increased blood pressure. Objective To compare waist circumference, BMI, and skinfold thickness as potential risk factors for hypertension in adolescents. Methods This cross-sectional study was conducted in May 2014 in three senior high schools in Medan, North Sumatera, and included 253 students with normal urinalysis test. All subjects underwent blood pressure, waist circumference, tricep- and subscapular-skinfold thickness (TST and SST), body weight, and body height measurements. The study population was categorized into underweight, normoweight, overweight, and obese, according to four different criteria: waist circumference, BMI, TST, and SST; all variables were analyzed for possible correlations with systolic and diastolic blood pressure. Results There were significant positive correlations between systolic blood pressure and waist circumference (OR 7.933; 95%CI 2.20 to 28.65; P=0.011) as well as BMI (OR 4.137; 95%CI 1.16 to 14.75; P=0.041). There were also significant correlations between diastolic blood pressure and waist circumference (OR 3.17; 95%CI 1.83 to 5.51; P=0.002), BMI (P=0.0001; OR=3.69), TST (OR 4.73; 95%CI 2.31 to 9.69; P=0.0001), and SST (OR 3.74; 95%CI 2.35 to 5.94; P=0.0001). Multivariate analysis showed that waist circumference was a predictive factor for systolic blood pressure (OR 9.667), but not for diastolic blood pressure. Conclusion Waist circumference is the strongest, significant, predictive factor for elevated systolic blood pressure; meanwhile BMI, SST, and TST could be predictive factors for elevated diastolic blood pressure. 
Impact of iron therapy on Mentzer index and red cell distribution width index in primary school children with iron deficiency anemia Ferdian, Budi Andri; Rosdiana, Nelly; Lubis, Bidasari
Paediatrica Indonesiana Vol 49 No 4 (2009): July 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.651 KB) | DOI: 10.14238/pi49.4.2009.195-9

Abstract

Background Iron deficiency anemia (IDA) remains a commonnutritional problem, especially in school-age children. Due tothe many examinations that are needed to be performed and the invasive gold standard procedure, an easy and simple alternative examination to diagnose IDA is needed.Objective To determine the impact of iron therapy on Mentzerand red cell distribution width (RDW) indexes of children withIDA.Methods A randomized open clinical trial was conducted inprimary school aged children in North Aek Nabara, betweenNovember 2006 and November 2007. IDA was determined basedon WHO criteria. Subjects with severe anemia were excluded.Subjects were randomly assigned to groups that received eitheriron therapy or a placebo.Results Three-hundred subjects from aged 9 to 12 years oldwere recruited and 104 subjects completed the study. The meanRDW index of the iron and placebo groups after three monthsobservation were 239.96 (SD 39.25) and 235.17 (SD 31.77),respectively. The mean Mentzer index mean for the iron therapyand placebo groups after three months observation were 16.08(SD 1.98) and 16.20 (SD 2.27), respectively.Conclusion After therapy, there are no significant differences ineither the Mentzer or RDW indexes between the therapy andplacebo groups.
Mature Teratoma Intrapulmonary in Adolescent SIREGAR, OLGA RASIYANTI; LESTARI, WAHYUNINGSIH; ROSDIANA, NELLY
Indonesian Journal of Cancer Vol 8, No 2 (2014): April-Juni 2014
Publisher : "Dharmais" Cancer Center Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mature teratoma is the most common primary germ cell tumor in the mediastinum, but very rare in the lung. A very rare case of mature giant intrapulmonary teratoma in a 14 year old female is reported. She had chronic cough, recurrent fever, chest pain, weight loss and history of breathless for six months. A chest x-ray showed a large mass with atelectasis of the left lung and thoracic CT scan revealed a giant neoplasm of the left lung, sized about 13x19 cm with calcification. The patient underwent left thoracotomy posterolateral, the tumor was totally resected with pneumonectomy. The histopatological examination revealed a mature teratoma. Intrapulmonary teratoma is very rare tumors with nonspecific signs and symptoms. Total removal tumor is the treatment of choice for this type of teratoma.
Tata Laksana Ekstravasasi Karena Pemakaian Kemoterapi Rosdiana, Nelly
Indonesian Journal of Cancer Vol 3, No 2 (2009): Apr - Jun 2009
Publisher : "Dharmais" Cancer Center Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.045 KB)

Abstract

Ekstravasasi merupakan suatu keadaan yang bisa muncul pada pasien kanker yang mendapat kemoterapi, yang menimbulkan rasa sakit dan eritema, ulkus, serta kerusakan jaringan. Beberapa obat sitostatika dapat bersifat vesicant, iritan, dan nonvesicant. Tata laksana ditentukan dari stadium ekstravasasi, banyaknya cairan yang terpapar, dan ketersediaan antidotum yang spesifik.Kata kunci: ekstravasasi, kemoterapi, tata laksana.
“Cerebral Salt-Wasting Syndrome” pada Leukemia Limfoblastik Akut Lubis, Bidasari; Agustian, Leon; Rosdiana, Nelly; -, Rusdidjas
Indonesian Journal of Cancer Vol 2, No 4 (2008): Oct - Dec 2008
Publisher : "Dharmais" Cancer Center Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1046.493 KB)

Abstract

Pada pasien leukemia limfoblastik akut (LLA), cerebral salt-wasting (CSW) syndrome dapat terjadi disebabkan renal salt-wasting karena gangguan reabsorbsi natrium di tubulus ginjal, yang mungkin dimediasi oleh brain natriuretic hormone / peptide. Hiponatremi pada CSW syndrome berhubungan dengan peningkatan eksresi natrium urin, peningkatan volume urin, hipovolemia, kadar asam urat normal atau meningkat, kadar vasopresin berkurang dan konsentrasi atrial natriuretic peptide meningkat.Laporan kasus ini seorang anak laki-laki usia 7 tahun yang menderita LLA dan CSW syndrome. Kami mendiskusikan tentang kesulitan dalam menegakkan diagnosis, efek dari hiponatremia, dan tatalaksana untuk menjaga kadar natrium darah dalam batas normal.Tatalaksana meliputi koreksi dengan NaCl 3 % intravena dan pemberian kapsul garam. Diperlukan pemantauan kadar natrium darah yang ketat dan gejala CSW syndrome.Kata Kunci: cerebral salt-ivasting syndrome, leukemia limfoblastik akut.
Terapi dan Suplementasi Besi pada Anak Gunadi, Dedy; Lubis, Bidasari; Rosdiana, Nelly
Sari Pediatri Vol 11, No 3 (2009)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp11.3.2009.207-11

Abstract

Anemia defisiensi besi (ADB) merupakan jenis anemia yang paling sering ditemukan di dunia, terutama di negara yang sedang berkembang. Hal ini sehubungan dengan kemampuan ekonomi yang terbatas, masukan protein hewani yang rendah, dan infestasi parasit. Dari hasil survei rumah tangga di Indonesia pada tahun 1995 didapati ADB 40,5% pada anak balita dan 47,2% pada anak usia sekolah. Defisiensi besi dapat menyebabkan gangguan terhadap respon imun sehingga rentan terhadap infeksi, gangguan gastrointestinal, gangguan fungsi kognitif, tumbuh kembang, dan perubahan tingkah laku. Diagnosis ditegakkan berdasarkan gejala pucat menahun tanpa disertai perdarahan maupun pembesaran organ dan dipastikan dengan pemeriksaan kadar besi dalam serum. Terapi besi dengan dosis 3-6 mg besi elemental/kgBB/hari diberikan kepada semua pasien ADB dengan monitor kenaikan kadar hemoglobin setelah 2-4 minggu. Terapi dilanjutkan 4-6 bulan setelah kadar hemoglobin mencapai normal untuk menambah isi cadangan besi, dan terapi terhadap penyakit dasarnya harus diberikan. Suplementasi besi harus diberikan pada bayi yang mempunyai risiko tinggi terhadap kejadian ADB seperti bayi berat badan lahir rendah (BBLR), prematur, bayi yang mendapat susu formula rendah besi, dan bayi lahir dari ibu yang menderita anemia selama kehamilan
Gambaran Klinis dan Laboratorium Retinoblastoma Rosdiana, Nelly
Sari Pediatri Vol 12, No 5 (2011)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp12.5.2011.319-22

Abstract

Latar belakang. Retinoblastoma adalah tumor endoocular pada mata yang mengenai syaraf embrionikretina,bisa terjadi unilateral atau bilateral. Retinoblastoma bisa terjadi intraokular atau menyebar keluarmata dan ekstraokular. Gejala klinis bervariasi sesuai stadium penyakit saat datang. Pemeriksaan yangpenting untuk diagnosis adalah pemeriksaan mata dengan Opthalmoscopy indirect, USG, CT scan, danMRI. Pemeriksaan-pemeriksaan sangat berguna untuk mengevaluasi nervus optikus, orbital, keterlibatansistem saraf pusat, dan adanya kalsifikasi intraokular.Tujuan. Menilai gambaran klinis dan laboratorium retinoblastoma unilateral dan bilateral pada anak.Metode. Penelitian retrospektif dari data rekam medis pasien retinoblastoma yang dirawat sejak awal Januari2005-31 Desember 2009 di Bagian Anak RS H. Adam Malik, Medan.Hasil. Pada periode lima tahun didapatkan 61 pasien Retinoblastoma, 53 kasus unilateral dan 8 bilateral.Rerata usia 3,2 (1,98) tahun pada unilateral dan 3,5 (3,50) tahun pada bilateral. Lama gejala 3,5 (3,56) bulanuntuk unilateral dan 2,1 (1,64) bulan pada bilateral. Keluhan utama yang ditemukan adalah mata menonjol(proptosis) 40 kasus (54,1% dan 11,4%). Pemeriksaan laboratorium didapati anemia ringan rerata Hb(10,7±2,04) pada unilateral dan (10,7±1,29) pada bilateral, nilai leukosit didapati (9806,5±3208,4)/mm3dan12,245,0±9208,6/mm3, jumlah trombosit didapati (411,957,0±183,951,1)/mm3 dan (458,500,0±134,040,2)/mm3, dan status gizi 68,8% masih baik (35 kasus Unilateral dan 7 kasus bilateral).Kesimpulan. Pada retinoblastoma unilateral dan bilateral gambaran klinis proptosis, anemia ringan danstatus gizi masih baik saat pasien datang pertama kalinya ke rumah sakit.
Perbedaan Respon Hematologi dan Perkembangan Kognitif pada Anak Anemia Defisiensi Besi Usia Sekolah Dasar yang Mendapat Terapi Besi Satu Kali dan Tiga kali Sehari Lubis, Bidasari; Saragih, Rina AC; Gunadi, Dedi; Rosdiana, Nelly; Andriani, Elvi
Sari Pediatri Vol 10, No 3 (2008)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp10.3.2008.184-9

Abstract

Latar belakang. Anemia defisiensi besi (ADB) dapat menyebabkan gangguan belajar dan mental dalam jangka panjang, bahkan dapat menetap. Tingkat kepatuhan pengobatan yang diberikan tiga kali sehari masih rendah. Hal ini dapat ditingkatkan dengan pemberian satu kali sehari sehingga diharapkan pengobatan akan berhasil.Tujuan. Membandingkan respon pengobatan pada pemberian sulfas frosus satu kali sehari dengan 3 kali sehari pada anak usia sekolah yang menderita anemia defisiensi besi.Metode. Penelitian dilakukan di Kecamatan Bilah Hulu, Kabupaten Rantau Prapat terhadap murid sekolah dasar. Anak dengan Hb <12, hipokrom mikrositer, Mentzer Index >13 dan RDW index >220 diikutsertakan dalam penelitian. Fungsi kognitif dinilai dengan Weschler Intelligence Scale for Children. Sampel secara random dibagi menjadi 2 kelompok yang mendapat sulfas ferosus 3 kali sehari dan satu kali sehari dengan dosis yang sama (besi elemental 5 mg/kgBB/hari).Hasil. Lima puluh anak dinilai dengan WISC, didapati rerata Full IQ 83,80 (SD=13,14), Performance IQ 81,08 (SD=14,58) dan Verbal IQ 88,10 (SD=14,20). Didapatkan skor aritmatika yang rendah (7+3,23). Tingkat IQ didapati average 36%, dull normal 28%, borderline 24%, dan mental defective 10%. Konsentrasi yang rendah dijumpai pada 44% dan sangat rendah 10%. Terdapat peningkatan bermakna kadar hemoglobin pada kedua kelompok setelah pemberian terapi besi (p<0,05), namun tidak dijumpai perbedaan bermakna peningkatan Hb antar kedua kelompok (p=0,29).Kesimpulan. Full IQ anak sekolah dasar yang menderita anemia defisiensi besi tidak melebihi tingkat average, didapati gangguan konsentrasi dan fungsi kognitif, terutama dalam matematika. Tidak didapati perbedaan bermakna antara kelompok terapi besi tiga kali sehari dibandingkan satu kali sehari dalam peningkatan Hb.