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Journal : BERKALA FISIKA

Solusi Numerik Model Dinamik Perlakuan Immunotherapy pada Infeksi HIV-1 Kartono, Agus; Rosidah, Rosidah; Arif, Ardian
BERKALA FISIKA Vol 13, No 1 (2010): Berkala Fisika
Publisher : BERKALA FISIKA

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Abstract

There are several types of treatment options that can slow the progression of HIV that can be offered if the number of CD4 + cells has been known for certain, one treatment is by immunotherapy with interleukin-2 (IL-2). This type of treatment is to increase the immune system that can help the body fight against the infection itself. Efforts to raise an immune response would be appropriate to reduce the amount of virus. This brings new hope for treatment of HIV infection and the type of treatment is being researched. Interleukin-2 (IL-2) is most of the cytokines which are proteins made by the body. T-helper cells, a type of white blood cells, produce IL-2 when they were stimulated by infection. In this study, a model of HIV disease progression than individuals not treated can be expressed in a mathematical model, and also expressed immunotherapy model to see the dynamics of viral populations and the population of CD4 + T cells from HIV disease based on ordinary differential equation (ODE). This study aims to calculate the numerical solution immunotherapy mathematical model in HIV infection and a mathematical model to predict the outcome of immunotherapy treatment strategies in HIV infection. Keywords: HIV, CD4 + T cells, immunotherapy, mathematical modeling
Co-Authors Abdillah, Abi Muhamad Abdul Haris Achmad Rizal Adhi Kusumastuti Afpriliansyah, Muhammad Rionaldhie Afpriliansyah, Muhammad Rionaldhie Aghnia, Wildan Nururfan Agus Kartono Ami Tjitraresmi, Ami Andiyani, Wulan ANGELA MARIANA LUSIASTUTI Arantika, Tina Ardian Arif Asih Kuswardinah Ayi Yustiati Cahya K, Vicky Cahyaningtyas, Rizqia Chrismadha, Tjandra Dahlan Rabbani, Muhammad Danang Dwi Saputro Denny Satria, Denny Dermawan, Rifai H. Subky, Badruddin Handaka, Asep Agus Handayani, Alfina Haro, Ginda Hasibuan, Poppy Anjelisa Zaitun Henry Ananta Herawati, Erni Himyati, Rida Irawan Suntoro Iskandar Iskandar Isti Hidayah Joko Kumoro Karsinah Karsinah, Karsinah Kiki Haetami Lumadya Adi, Lumadya Luqman, Luqman Lusyani, Lusyani Mardiati, Yayah Margunani Margunani, Margunani Muhamad Yuliadi Rahman Muhammad Ansori Muhammad Fajar Munastiwi, Erni Muslikhah Dwihartanti, Muslikhah Nadia Sasmita Wijayanti, Nadia Sasmita Nana Kariada Tri Martuti, Nana Kariada Tri Ningrum, Rahma Farah Noor Mirad Sari Octavianti Paramita Otang Kurniaman Puji, Puji Purwanto Purwanto Rahmat Doni Widodo Rosyidah, Khasanatur Rustiani, Tenni Samsudin Anis Septianarta, Stella Setiadharma, Gunawan Setiadharma, Gunawan Siti Fathonah Siti Harnina Bintari Siti Sopiah, Siti Sriati Sriati, Sriati Sucityasingrum, Ratri Sunyoto Sunyoto Supomo Kandar Suprijati, Jajuk Suranto Aw Suryadi, Ibnu Bangkit Suryadi, Kusumasari Suryadi, Kusumasari Taukhid Taukhid, Taukhid Titin Agustina Ujang Subhan Vivi Suzanna Dewi, Vivi Suzanna Walim Lili Yuli Andriani Yuliansah Yuliansah, Yuliansah Yuniar Mulyani Z. Hasibuan, Poppy Anjelisa Zariul Antosa