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Journal : Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)

APOPTOSIS INDEX BETWEEN FEMALES AND MALES IN REGULAR HEMODIALYSIS Santoso, Djoko
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 19, No 3 (2013)
Publisher : PERHIMPUNAN DOKTER SPESIALIS PATOLOGI KLINIK INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v19i3.410

Abstract

Many reports have documented apoptosis index in hemodialysis patients, but to date, no single study has directly compared the?apoptosis index of males to females. Data on mortality rate among hemodialytic patients in the hemodialysis center at the Department of?Internal Medicine Dr Soetomo General Hospital, Surabaya, Indonesia show a high number predominated by female patients. Therefore,?to answer the question of whether there is a gender difference in apoptosis index, the researcher studied leukocyte responses in male and?female hemodialysis patients. The apoptosis index of the sample was measured by indirect immunoassay method. Cell lyses, followed?by immunochemical determination of histone-complexed DNA fragments in a microtiter plate wells. The apoptosis quantization was?obtained by determining the amount of colored product spectrophotometrically. One hundred and four non-diabetic subjects who?received hemodialysis (HD), and 24 normal controls (NC), were evaluated. The apoptosis index in ESRD patients group and control?group showed no significant difference (0.6172 vs 0.4008, p=0.114), neither did it vary in both sexes and age groups. When the sex?factor was analyzed (after exclusion from the diabetic ESRD patients), females apoptosis index was significantly higher than that of the?males (0.7325 vs 0.55175, p<0.05). In conclusion, apoptosis index in females among non-diabetic patients undergoing hemodialysis?is higher than that occur in males and controls.
Co-Authors . Mansyurdin . Siswanto . Suharyanto . SYAFARUDDIN, . Aditia Wardana, Aditia Aditiawardana Aditiawardana, Aditiawardana Agung Dwi Indrawan Ahmad Fauzi AHMAD RIDUAN Aida Farida Alda, Rieza Rizqi Alsagaff, Mohammad Yusuf AMANAH, Dian Mutiara Amin, Mochammad Andre Noevi Rahmanto Anton Subarno ANTONIUS SUWANTO Aprih Santoso, Aprih Ardityo R Ardhany, Ardityo R Arief Fathony, Ramlan Artaria Tjempakasari, Artaria Asmini Budiani Aswaldi Anwar ASWIDINNOO, Hajrial Auromiqo, Candra Ayu Larasati, Niken Baiti, Ahmad Awaluddin Bambang S Purwoko Bastin Fitriatus Hasanah Bekti Wulandari Bonita Destiana Budi Sulistijo Chandra Irwanadi Mohani, Chandra Irwanadi Chandra Irwanadi, Chandra Chibtiyah, Nur chieko Hamada, chieko D Ningsih, D Darda Efendi Darharta Dahrin DEDI SOLEH EFFENDI, DEDI SOLEH Empitu, Maulana Antiyan Endrizal ERIS, Deden Dewantara Fajar, Saiful Ferdiyono, J. Reza FITRANTI, Niyyah FITRANTY, Niyyah Fitriyah, Fauziatul GHONI, M. A. GHONI Ginanjar, Muhammad Syukron HABIBULLAH, Hanning Susilo Haerani Rasyid, Haerani HAJRIAL ASWIDINNOOR Hakim, Zaky El Hamidah, Berliana HANDAYAN, Agustina A. HAPPY WIDIASTUTI Hasanatuludhhiyah, Nurina Hasanuddin Z. Abidin Hasanuddin Z. Abidin, Hasanuddin Hayati Minarsih Hendra Grandis I GEDE PUTU WIGENA I Haryoko, I Ichiyu Shou, Ichiyu Imron Riyadi Indarto Indarto Indhira Hari Kurnia Ismail, Mohd Erfy Isnu Irwantoro, Isnu JAYA, Abdul Mollah S. Joenil Kahar, Joenil Jumiyanto Widodo Kadariswantiningsih, Ika Nindya Kresnawaty, Irma KRESNAWATY, Irma Kunimi Maeda, Kunimi Laesanpura, Agus Laesanpura, Agus M Thaha, M MARAHIMIN, B. MARAHIMIN Mayta Novaliza Isda Medika, Decsa Mitsumine Fukui, Mitsumine MOCHAMMAD THAHA Moh. Yogiantoro, Moh. MS, Freddy Muhammad Jusuf Munadi Munadi Munir, Muh Musliar Kasim Muslikhin Muslikhin NIKOLAU, Basil J Nugroho, Cahyo Wibisono Nunuk Mardiana, Nunuk NURILMALA, F Nuryake Fajaryati PANJAITAN, K. PANJAITAN Pipit Utami Pradusuara, Franes pranawa pranawa, pranawa PRIYONO, . PURBA, A.R. PURBA Putra, Abdul Aziz Sidiq Tri PUTRANTO, Riza A PUTRANTO, Riza A. Putri, Eka Arum Cahyaning R.D.B LEFROY Raduan, Atiqah Renita Renita Rita Hayati ROEDHY POERWANTO Rokib, Muhammad Nur Saddewisasi, Wyati Sadewisasi, Wyati SAMANHUDI, . Saptowo Jumali Pardal, Saptowo Jumali SARAGIH, A. H. SARAGIH SARI, Dini Astika Satoshi Horikoshi, Satoshi SINAGA, Jisman Slamet Slamet Soekarno Mismana Putra, Soekarno Mismana soewanto soewanto, soewanto Sri Hendrastuti Sri Wahyuni Sri Waluyanti Subagus Wahyuono Sudarsono SUDARSONO SUDARSONO Sugeng Riyanto Sugiyanto Sugiyanto Sukarti Moeljopawiro Suparman Suparman Suryansyah, Maulana Muhtadin SUSANTI, Paramitha Suzuki, Yusuke SYARIEF, Auzar Tetty Chaidamsari, Tetty Tri Harso Karyono Tri P Asmarawati, Tri P TRI-PANJI, . TRIASTANTO, Oktaviany Ferry Trisintyandika, Idkha UMAHATI, Binti Khurotul Umi Rochayati Umi Rokhayati, Umi Vera Sadarviana, Vera Wahyudi W. Parnadi Warsa Warsa Wawan Gunawan A. Kadir Wedyanto K, Wedyanto Widodo Widodo Widyastuti, SM Windari, Era Nurisa WIRAMIHARDJA, Memed Y, Yatini Yasuhiko Tomino, Yasuhiko yatini, yatini Yusniwati Yusniwati