Indrawati Sendow
Bagian Klinik Hewan, Fakultas Kedokteran Hewan, Universitas Udayana, Bali

Published : 59 Documents
Articles

KINETIKA IMMUNOGLOBULIN KUNING TELUR ANTIPARVOVIRUS ANJING PADA ANJING (KINETICS OF ANTICANINE PARVOVIRUS YOLK IMMUNOGLOBULIN IN DOGS) Suartini, I Gusti Ayu Agung; Sendow, Indrawati; Agustini, Ni Luh Putu; Suprayogi, Agik; Wibawan, I Wayan Teguh; Mahardika, I Gusti Ngurah Kade
Jurnal Veteriner Vol 17 No 2 (2016)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Kinetic study on Anti CPV IgY has been performed on six dogs aged 5-10 months. The IgY was injectedintravenously at dose of 21.4mg /10kg body weight. IgY levels in the blood were determined by ELISA. Aresearch was conducted to find out the kinetics of Anti CPV IgY in dogs blood. The kinetics of IgY wascalculated by using regression analysis to determine the association on the levels of IgY in serum againsttime at injection. The results showed that kinetic parameters were calculated based on first order kinetics.The constant elimination rate of IgY was at the range between 0.007 to 0.015 / h. IgY concentration in thedogs blood was from 0.746 to 0.992 mg / mL. The half-life of IgY was from 1.65 to 4.01 / d. Volumedistribution of IgY was between 21.47 to 28,55 / mL. Total IgY in the dog bodies (AUC) was from 42,60 to142,00 mg / mL.h. The duration of the IgY in the dog?s body was 3.08 to 8.51 days. Clearance time of IgY was0.15 to 0.50 mL / h. In conclusion the kinetics of anti CPV IgY in dog?s body follow one compartment andfirst order model, which are only distributed in the blood with the half-life at 2.5 days, and IgY has lesspossibility to accumulate in the body compared to the IgG.
IDENTIFICATION AND CHARACTERIZATION OF BOVINE VIRAL DIARRHEA VIRUS FROM INDONESIAN CATTLE (IDENTIFIKASI DAN KARAKTERISASI VIRUS BOVINE VIRAL DIARRHEA DARI SAPI INDONESIA) Saepulloh, Muharam; Sendow, Indrawati
Jurnal Veteriner Vol 16 No 1 (2015)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Bovine viral diarrhea virus (BVDV) is an important viral disease, which a ubiquitous pathogen ofcattle with worldwide economic importance and due to its misdiagnose with other viruses. The goal of thecurrent study was to identify and characterize of BVDV by reverse transcriptase polymerase chainreaction (RT-PCR) and followed by sequence genome analyses. Blood, feces, and semen samples werecollected from 588 selected cattle from animals suffering from diarrhea and respiratory manifestation. RTPCRresults showed that the 69 (11.74%) samples were positive to BVDV. Further molecularcharacterization was conducted only with 17 PCR positive samples. The results indicated the 17 IndonesianBVD virus isolates were belonging to the genotype-1 of BVDV (BVDV-1) based on sequence analysis anda phylogenetic relationship between Indonesian BVDV isolates and BVDV in the world. This finding is thefirst report of BVD-1 circulated in Indonesian cattle.
The Development of Japanese Encephalitis in Indonesia Sendow, Indrawati; Bahri, Sjamsul
WARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences Vol 15, No 3 (2005): SEPTEMBER 2005
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (826.844 KB) | DOI: 10.14334/wartazoa.v15i3.821

Abstract

Japanese encephalitis (JE) is a zoonotic viral disease which causes encephalitis in children (5-9 years old) . The disease is transmitted by mosquitoes. The presence of JE virus, vector and reservoir host in Indonesia, will increase the concern of the possibility of JE outbreak in Indonesia. JE infection in human was reported by clinical and serological findings. Recently, JE case in Bali was declared as hyperendemic (usually sporadic) . In animals, JE infection has been confirmed by serology and viral isolation, while JE vector had been found in different species of mosquitoes by successful viral isolation from those mosquitoes. The prevention and control of JE are conducted by socialization about JE to the society, by cutting the JE transmission cycle (virus, vector and host), including pig farm relocation . The development of regional laboratories (facilities and human resources) to diagnose JE and the establishment BSL of 3 laboratory in the central laboratory institute to isolate the JE virus and to conduct further JE research on the role of animal in transmitting JE to human, must be conducted . Key words : Japanese encephalitis, epidemiology, diagnose, animals, human
Canine Parvovirus in Dogs Sendow, Indrawati
WARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences Vol 13, No 2 (2003): JUNE 2003
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.669 KB) | DOI: 10.14334/wartazoa.v13i2.787

Abstract

Parvovirus disease in dogs is caused by Parvovirus, a member of famili Parvoviridae. In young puppies, less than 4 months age, CPV infect heart, while older puppies CPV will infect tractus digestivus, which caused blood diarrhoea. In general, the cinical signs of CPV disease are vomit, loss appetite, and blood diarrhoea. Parvovirus will inactivated by given chemical reagents such as Hypoclorised or formalin. Vaccination is the only way to protect the disease. The right time of vaccination will give the optimum protection of the disease. Hence, monitoring the immune response after vaccination needs to be developed to gain the information on the best time to vvaccinate the dogs, so the failure of vaccination can be avoided.   Key words: Parvovirus, vaccination, diagnosis
Peste des Petits Ruminant: Exotic Ruminant Disease That Should Be Anticipated Sendow, Indrawati; RMA, Adjid; Dharmayanti, NLPI
WARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences Vol 24, No 1 (2014): MARCH 2014
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.458 KB) | DOI: 10.14334/wartazoa.v24i1.1025

Abstract

Peste des Pettits Ruminants (PPR) is one of infectious and contagious viral diseases from morbilliviruses group in ruminants especially small ruminants. The disease was characterized by nasal and eye discharge, conjunctivitis, high fever, gastrointestinal disorder and pneumonia. Hence PPR may cause economical impact for the farmers due to the decrease of animal productivity and death.  Peste des pettits ruminants is also a disease that has serious attention on the Office International des Epizooties (OIE) list. In Indonesia, the disease has not been reported, so the anticipation of entering the disease is needed. The paper will describe the disease in many aspects included transmission, host ranges, epidemiology, clinical disease, diagnosis and the ability to identify the disease in Indonesia. Key words: Peste des Pettits Ruminants, epidemiology, diagnose, ruminants
Nipah and its Current Situation in Indonesia Sendow, Indrawati; Adjid, R M Abdul
WARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences Vol 15, No 2 (2005): JUNE 2005
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (556.921 KB) | DOI: 10.14334/wartazoa.v15i2.828

Abstract

Recently, the incidence of zoonotic disease in the world increases, due to technology development, human activities and ecosystem changes . One of these diseases is an outbreak of Nipah in the neighbouring country, Malaysia, which caused 105 people died and more than one million pig were culled . Malaysia is the adjacent country to Indonesia, hence, it is possible that Nipah will be transferred to Indonesia through imported pigs and their products, and the migration of wild animal such as fruit bat. Because of Nipah is one of emerging diseases and hazardous to human, it needs a serious attention . Preliminary results on Nipah serology at the Research Institute for Veterinary Science . Bogor .. indicated that pigs in Riau. North Sumatera . North Sulawesi and West Jawa areas were negative to Nipah virus infection . However, the reservoir host, fruit bats from North Sumatera, West Java and East Java areas had been proven to have antibodies against Nipah virus using both ELISA and serum neutralization tests . With this condition, human and animal health departments should anticipate a possible occurrence of Nipah viral infection in Indonesia . This paper reviewes many aspects of Nipah included aetiology, epidemiology, the situation in Indonesia, prevention and controlling recommendation, that can be used as an input in order to improve veterinary public health in Indonesia. Key words: Nipah, aetiology, epidemiology, controlling, Indonesia
Status Infeksi Virus Hendra Pada Kalong (Pteropus spp.) di Pontianak, Kalimantan Barat dan Manado, Sulawesi Utara Sendow, Indrawati; Field, Hume; Ratnawati, Atik; Adjid, RM. Abdul; Saepulloh, Muharam; Breed, Andrew; Morrissy, Chris.; Daniels, Peter
JURNAL BIOLOGI INDONESIA Vol 9, No 1 (2013): JURNAL BIOLOGI INDONESIA
Publisher : Perhimpunan Biologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/jbi.v9i1.144

Abstract

Hendra merupakan salah satu penyakit emerging dan zoonosis yang berbahaya, termasuk Genus Henipavirus(Paramyxoviridae). Penyakit ini sangat erat hubungannya dengan Nipah, yang dapat menginfeksi ternak babi danmanusia. Survey serologi dilakukan di dua propinsi, yaitu Kalimantan Barat dan Sulawesi Utara. Hasil menunjukkanbahwa 148 kalong (Pteropus sp.) yang terdiri dari 84 P. vampyrus asal Kalimanatan Barat dan 64 P alecto asalSulawesi Utara telah dikoleksi. Hasil serologis mengindikasikan 22,6% P vampyrus di Kalimantan Barat mempunyaiantibodi terhadap virus Hendra, yang juga merupakan reaksi silang dengan virus Nipah. Di Sulawesi Utara, 25%serum mengandung antibodi terhadap virus Hendra, dimana 7,8% diantaranya hanya mempunyai antibodi terhadapvirus Hendra. Dari data tersebut dapat disimpulkan bahwa antibodi terhadap virus Hendra terdeteksi padaP. alecto di Sulawesi Utara. Hasil ini merupakan laporan pertama tentang infeksi Hendra pada P. alecto di Indonesia.Adanya perbedaan prevalensi tersebut, dapat disebabkan oleh letak geografis atau spesies kalong yang diuji.Kata kunci: P. vampyrus, P. alecto, antibodi, Hendra, Nipah, Serum Netralisasi
Hantavirus Infection: Anticipation of Zoonotic Disease in Indonesia Sendow, Indrawati; Dharmayanti, NLPI; Saepullah, M; Adjid, RMA
WARTAZOA. Indonesian Bulletin of Animal and Veterinary Sciences Vol 26, No 1 (2016): MARCH 2016
Publisher : Indonesian Center for Animal Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (156.031 KB) | DOI: 10.14334/wartazoa.v26i1.1270

Abstract

Recently, the evidence of Hantavirus infection in human and animals is increasing, and new Hantavirus strain has been identified. The disease causes clinical renal and lung disorders and fatal to human. The presence of new Hantavirus strain, lack of available quick and accurate diagnostic tool, asymptomatic clinical signs and paucity of disease information, will inhibit disease control especially in the developing countries. The paper describes Hantavirus disease and its epidemiology in developed and developing countries, including Indonesia and its recommendation for disease prevention and control.
Bovine Ephemeral Fever As A Disease Related To Climate Change Sendow, Indrawati
Indonesian Bulletin of Animal and Veterinary Sciences Vol 23, No 2 (2013)
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (172.254 KB) | DOI: 10.14334/wartazoa.v23i2.717

Abstract

Bovine Ephemeral Fever (BEF) is one of arbovirus diseases infecting in ruminants especially cattle and buffaloes, which istransmitted by mosquito vectors. In general, vector borne disease is also related to climate change, that mosquito as a vector will significantly increase when the environment temperature increases. The disease was found in many countries in Asia, Africa and Australia. The clinical sign of the disease such as fever to paralysis causes economical impact to the farmer, eventhough the mortality is very low. This review will discuss the disease in relation to climate change, which affects vector population that spread the disease. The more population of vector is the higher chance of animal to be infected. This condition describes that the spread of BEF will depend on some factors included the increase of vectors, the availability of susceptible host and vector media facilities, climate condition and supportive ecology. This paper will discuss the feature of BEF, mode of transmission, the impact of environment and climate change, disease prevention and control, and other aspects to prevent further economical impact. It will also discuss how to the transmission, prevention and control of disease BEF. The information can be taken as an input for policy makers to prevent BEF infection in Indonesia.Key words: Bovine ephemeral fever, epidemiology, vector, diagnosis, climate change
The Overview of Japanese Encephalitis and Nipah Diseases Sendow, Indrawati
Indonesian Bulletin of Animal and Veterinary Sciences Vol 10, No 2 (2000)
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (272.057 KB) | DOI: 10.14334/wartazoa.v10i2.742

Abstract

An outbreak of encephalitis in Malaysia, caused a panic among Veterinary and animal husbandry expert internationally in late 1998. Suspected Japanese encephalitis (JE) had been eliminated after an intensif investigation to diagnose the outbreak. The result indicated that Nipah virus played an important role caused the outbreak. Controversion on causative agent between JE and Nipah leads to further discussion on the difference and similarities between JE and Nipah from different aspects included their aetiology, clinical signs, host, diagnosis and control the disease.   Keywords: Japanese encephalitis, nipah