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DESCRIPTION OF THE RESULT OF THE EXAMINATION OF PAP SMEAR AFTER RADIATION THERAPY ON CERVICAL CANCER PATIENTS BASED ON THE TYPE OF CELL AT ARIFIN ACHMAD GENERAL HOSPITAL PEKANBARU IN THE PERIOD 2009-2013 Sofian, Amru; Gaffar, Mardhiah; Yulis, Trigen Yulis Rahmat
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is the second most for women in the world. Cervical cancer most often found in advanced stage. The main therapy for advanced stage cervical cancer is radiation therapy. Radiation is also used as therapy for early stage of cervical cancer patient who is not eligible for surgery. Radiation is divided into two, externa radiation and internal radiation. In RSUD Arifin Achmad Pekanbaru is only using externa radiation caused by limitation of the tools on interna radiation. After the complete radiation, patients will do pap smear as follow up to analyse the cell cancer. This research has been done in Radiotherapy Installation, Pathology Anatomic Installation, and Medical Record Installation in RSUD Arifin Achmad. This research uses a descriptive retrospective design by taking a patient's medical record of cervical cancer in RSUD Arifin Achmad period 2009-2013. The result showed that squamous cell carcinoma is the most histhopathology in cervical cancer. 30 of 78 cervical cancer patients who had been in radiation therapy continue to follow up pap smear. The result of pap smear test showed that there are non-malignant cell in 26 patients and the type of cell is squamous cell carcinoma and adenocarcinoma in 2 patients. And in 2 adenocarcinoma patient is found malignant cells. There is a cervical cancer patient with squamosa cell carcinoma who experienced recurrence at 7-9 months after radiation.Keyword : cervical cancer, radiation, pap smear
HUBUNGAN TUMOR MARKER CA-125 DENGAN SIFAT DAN TIPE SEL TUMOR OVARIUM DI RSUD ARIFIN ACHMAD PEKANBARU Ferdyansyah, Tryanda; Sofian, Amru; ", Fatmawati
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Ovarian tumor caused by inflammation or proliferation of ovarian’s ephitelial, germinal, stroma cell and it can be benign and malignant. Ovarian tumor had many tumor markers, the most known is Cancer Antigen 125 (CA-125). The normal concentration of CA-125 is <35 IU/ml. CA-125 could be used to predict a malignancy with cut off value ≥35 IU/ml. However, some benign conditions can be found with value ≥35 IU/ml, and some malignancy conditions with normal CA-125 concentration. The purpose of this research was to know correlation between CA-125 with the ovarians tumor malignancy and cell type. This research used retrospective design which involving 206 samples. The characteristic and cell type was based on histopathologycal examination and the value of CA-125 was based on clinical pathology laboratory test result. From 136 patients with benign ovarian tumor, 80 (57,5%) with CA-125 was still in normal limit and 59 (42,5%) was increased. From 67 patients with malignant ovarian tumor, 23 (34,3%) with CA-125 was still in normal limit and 44 (65,7%) was increased. This research showed there was a significant correlation between tumor marker CA-125 with the ovarians tumor malignancy (p =0,002), ephitelial cell type (p=0,001), and germinal cell type (p=0,001).Key words : ovarian tumor, ovarian tumor marker, Cancer Antigen 125, ovarian tumors malignancy and cell type
GAMBARAN HASIL TERAPI RADIASI DAN KEMORADIASI PASIEN KANKER SERVIKS DI RSUD ARIFIN ACHMAD PEKANBARU PERIODE 2009-2013 Putri, Fadilla Rizki; Sofian, Amru; Nugraha, Dimas Pramita
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is the third most common cancer in women in Indonesia. Many cervical cancer cases were found in an advanced stage, so that they were treated by radiation or chemoradiation. Radiation is divided into external radiation and internal radiation. There is no internal radiation done in Arifin Achmad General Hospital Pekanbaru, so that they only use complete external radiation treatment for 25 times. After the therapy, the patient will do a follow-up treatment of pap smears to assess the cancer cells. This research was conducted in Radiotherapy Installation, Pathology Installation and Medical Records Installation at Arifin Achmad General Hospital Pekanbaru to study and reveal the results of radiation and chemoradiation therapy in cervical cancer patients at Arifin Achmad General Hospital Pekanbaru. The results showed that of 79 patients treated with cervical cancer radiation, only 29 patients did the follow up treatment whilst of 31 patients treated with cervical cancer chemoradiation, only 6 patients did the follow up treatment. Only 2 patients treated by radiation were found to have malignant cells in the pap smear treatment. Meanwhile, in cervical cancer patients treated by chemoradiation, 2 patients were still found malignant cells and 1 patient experienced a recurrence. Once treated with radiation, malignant cells on pap smears are found only in 2 patients, while 27 patients were not found and only 1 patient who experienced a recurrence. After chemoradiation therapy in 6 cervical cancer patients who did the follow up, malignant cells are found in 2 patients and in 4 patients no malignant cells was found, while the other 2 patients experienced recurrence. The conclusion of this study is the incompleteness of the data found in the medical records, low patient adherence to do follow-up treatment after therapy, and the lack of education and information given by the health professionals to patients to do a follow up treatment.Keywords: Cervical cancer, Complete radiation , Chemoradiation, Pap smear
PROFIL PENDERITA TUMOR OVARIUM GERMINAL DI RSUD ARIFIN ACHMAD PROVINSI RIAU PERIODE JANUARI 2008 – DESEMBER 2012 Pratama, Gerry; Sofian, Amru; Chandra, Fifia
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Ovarian tumour is one of neoplasma that can be found on female genitalia system, which is formed by benign wether malignant ovarium cells and can be grouped by its origin such as epithelial, germinal, and stroma ovarian tumour. Age, parity, cancer in family history, menarche history and application of hormonal contraception can be risk factors to germinal ovarian tumour to occurs.This is a descriptive and retrospective study, conducted to discover profile of germinal ovarian tumour patients in General Hospital Arifin Achmad Riau Province. From General Hospital Arifin Achmad’s medical records on January 2008-December 2012, 78 cases of germinal ovarian tumour have been found, with the age of majority was in the age 23-32 years old (36,11%), most parity was multiparity (40,27%) and most commonly histopatological type was mature teratoma (76,39%). Cancer in family history can be found in 29 patients (40,27%) which about 17 patients with mature teratoma (23,61%), followed by 8 patients with dysgerminoma (11,11%) and 4 patients with immature teratoma (5,55%). Based on menarche history, distribution profile by the age of majority was 10-13 years old (58,3%). About 62,5% patients didn’t use hormonal contraception. Most commonly CA 125 tests with positive results were 18 examinations (25%) wich can be found mature teratoma on 12 examinations (16,67%) followed by dysgerminoma on 4 examinations (5,56%) and immature teratoma on 2 examinations (2,77%). CEA tests showed positive results for about 14 examinations (19,44%), where mature teratoma can be found on 8 examinations (11,11%), followed by dysgerminoma on 4 examinations (5,56%) and immature teratoma on 2 examinations (2,77%). Salphingoophorectomy were the most common therapy that have been chosen (54,17%).Keywords: ovarian tumour, germinal ovarian tumour, risk factors
GAMBARAN HASIL PEMERIKSAAN SITOLOGI PENDERITA KANKER SERVIKS PASCA TERAPI RADIASI BERDASARKAN KELOMPOK UMUR DI INSTALASI RADIOTERAPI RSUD ARIFIN ACHMAD PERIODE TAHUN 2009–2013 Herman, Awanda; Sofian, Amru; Chandra, Fifia
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Radiation therapy is a therapeutic option for cervical cancer, and expected to have optimal outcomes, The results of radiation therapy is different for each patient depending on the sensitivity of cancer cells to radiation that is influenced by age, it can be reviewed by looking at the cell's response to radiation based on the presence or absence of malignant cells that found in the results of cytologic examination after radiation therapy. This research aimed to describe the results of cytological examination of cervical cancer patients after radiation therapy by age group in Radiotherapy Installation Arifin Achmad general hospital of Riau Province Period 2009-2013. The type of this research was descriptive retrospective with population are medical recodrs of cervical cancer patients who had undergone radiation therapy in the form of 25 full time external radiation therapy without chemotherapy in Radiotherapy Installation Arifin Achmad General Hospital of Riau period 2009 to 2013. The sample is the medical record that eligible as population that is as much as 78 medical records. The result of this research was found the largest age group who performed radiation therapy was 40-49 years old (41%), while the largest age group who have a cytological examination found no malignant cells most is 40-49 years old (12.8%), the age group that has the results malignant cells are found in the form of the age group 40-49 years old and 50-59 years old with patients respectively (1.3%) and the largest age group who do not have the data post-radiation cytology result is 40-49 years old (26 , 9%). The largest age group who have a cytological examination found no malignant cells most is people who do a cytological examination more than once that is age group > 60 years old (55.6%) and resulted in the malignant cells are found in the age group 50-59 years old (11 , 1%). Key words: cervical cancer, cervical cancer radiation, cytology results based on age
Gambaran Kualitas Hidup Pasien Kanker Serviks Yang Menjalani Radioerapi Di RSUD Arifin Achmad Provinsi Riau Periode 2011 – 2013 ", Azizah; Sofian, Amru; ", Suyanto
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is a malignant tumor derived from primary squamous epithelial cells that grow on the surface of the epithelial or outer layer of the cervix, and is caused by virus infections Human Papiloma Virus (HPV). One of the given therapy on patients of cervical cancer is radiotherapy. Radiotherapy is done by people with cervical cancer that can affect the quality of life of the respondent which can be assessed by using the WHOQOL questionnair. The purpose of this research is to know the description of the quality of life of patients with cervical cancer undergoing radiotherapy. This research is descriptive research with cross sectional approach implemented in June 2014. There are 31 people with cervical cancer undergoing radiotherapy. From this research found the age of respondents in the age group 40-49 years 50-59 years and the age group 60-69 years were relatively the same lot. The majority of respondents were Malays (58,06 percent). Most respondents were the PRIMARY education (38,80). Most respondents work was as the IRT (90,32 per cent). The respondents underwent radiotherapy most within > 5 weeks (100%). On cervical cancer patients undergoing radiotherapy at the PROVINCIAL HOSPITAL Arifin Achmad Riau Province found the quality of life in both categories as much as 61,30%.Key word: cervical cancer, radiotherapy , quality of life
GAMBARAN PEMERIKSAAN INPEKSI VISUAL ASETAT SEBAGAI DETEKSI LESI PRAKANKER SERVIKS DI HOTSPOT JALAN TUANKU TAMBUSAI KECAMATAN SUKAJADI PEKANBARU Novri, Dhini Aiyulie; Sofian, Amru; Fidiawati, Wiwit Ade
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 1 (2014): Wisuda Februari Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is the third most frequent cancer in women in Indonesia.Indirect female sex worker are in high risk for having cervical cancer. WorldHealth Organization had recommended an alternative approach for developingcountries with down staging concept of cervical malignancy with visual inspectionwith acetic acid (VIA) to detect cervical precancerous lesion. This research wascarried out at hotspot Tuanku Tambusai Street, Pekanbaru aimed to describe thecharacteritics of respondent and to detect displastic cervical epithelial cells withVIA. The result showed from 31 indirect female sex worker, 52 % were diagnosedwith positive acetowhite appereance (positive VIA). Conclusion of the study thatdisplastic cervical epithelial cells of indirect female sex worker who has high riskfor having cervical cancer should be reffered for further follow up.Keywords: Visual inspection with acetic acid, Cervical cancer, Cervicalprecancerous lesion, Indirect female sex worker.
GAMBARAN PEMERIKSAAN INPEKSI VISUAL ASETAT SEBAGAI DETEKSI LESI PRAKANKER SERVIKS DI HOTSPOT JALAN TUANKU TAMBUSAI KECAMATAN SUKAJADI PEKANBARU Novri, Dhini Aiyuli; sofian, Amru; Fidiawati, Wiwit Ade
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Cervical cancer is the third most frequent cancer in women in Indonesia. Indirect female sex worker are in high risk for having cervical cancer. World Health Organization had recommended an alternative approach for developing countries with down staging concept of cervical malignancy with visual inspection with acetic acid (VIA) to detect cervical precancerous lesion. This research was carried out at hotspot Tuanku Tambusai Street, Pekanbaru aimed to describe the characteritics of respondent and to detect displastic cervical epithelial cells with VIA. The result showed from 31 indirect female sex worker, 52 % were diagnosed with positive acetowhite appereance (positive VIA). Conclusion of the study that displastic cervical epithelial cells of indirect female sex worker who has high risk for having cervical cancer should be reffered for further follow up.Keywords: Visual inspection with acetic acid, Cervical cancer, Cervical precancerous lesion, Indirect female sex worker.
Efektivitas HE4 sebagai Metode Skrining Terbaru untuk Diagnosis Dini Kanker Ovarium Sofian, Amru; Perkasa, Hendra; Evsya, Ega Rahman; Darundryo, Riyan M
Jurnal Ilmu Kedokteran Vol 5, No 2 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.844 KB) | DOI: 10.26891/JIK.v5i2.2011.88-93

Abstract

The tumor marker CA125 is one of the currently used biomarkers to detect ovarian cancer. The tumormarker CA125 also elevated in other diseases. Human epididymis protein 4 is used as a new biomarker forearly detection of ovarian cancer. Human epididymis protein 4 is increased in almost all patients withovarian cancer and increased only slightly at a fraction of other diseases. Human epididymis protein 4 hasa better effectiveness in detecting ovarian cancer when combined with CA125. From the study of literaturefound that the combination of HE4 and CA125 had a specificity of 96.3% and 92.9% sensitivity.
HUBUNGAN BODY IMAGE, ASUPAN ENERGI DAN AKTIVITAS FISIK DENGAN STATUS GIZI PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS RIAU ANGKATAN 2014 Serly, Vicennia; Sofian, Amru; Ernalia, Yanti
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

Adolescents is one of the groups vulnerable to negative issues regarding health and nutrition. Nutritional problems suffered by many adolescents is caused by various factors, such as body image, energy intake and physical activity. This study was conducted with the cross-sectional design with a sample selected with a total sampling method. Body image was assessed by questionnaire BSQ-34, obtained through food energy intake records 3x24 consecutive hours, physical activity obtained form 3x24 hour record of activity and nutritional status assessed by measuring BMI. Based on this study of 166 samples were obtained 56% of respondents are not satisfied with the sight of his body image, while the category of energy intake can be seen as much as 57.8% of respondents with moderate energy intake based AKE 2012. For the category of physical activity, can be known that 44% of respondents mild physical activity and as much as 43.4% of respondents normal nutritional status, 18.1% of respondents overweight nutritional status, 15.7% of respondents nutritional status as underweight, 13.9% of respondents nutritional status obese I and the remaining 9% of respondents nutritional status of obesity II. From the results of the analysis carried out there was significant relationship between body image and nutritional status (p = 0.000). There was a significant relationship between energy intake and nutritional status (p = 0.000) and there was significant association between physical activity and nutritional status (p = 0.000). So, there is a significant relationship (p <0.05) between body image, energy intake and physical activity with nutritional status on the students of the Faculty of Medicine, University of Riau Class of 2014.Key words: Adolescents, body image, energy intake, physical activity and nutritional status