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PREVALENSI KARIES DAN INDEKS d e f PADA MURID-MURID KELAS I, II, DAN III SEKOLAH DASAR YANG BERADA DI SEKITAR KLINIK KERJA MAHASISWA FAKULTAS KEDOKTERAN GIGI UNPAD Sufiawati, Irna; Setiani, Tenny; -, Dewi; Aripin, Dudi
Bionatura Vol 2, No 3 (2000): Bionatura Desember 2000
Publisher : Direktorat Sumber Daya Akademik dan Perpustakaan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (111.252 KB)

Abstract

Penelitian ini bertujuan untuk mengetahui gambaran umum tentang statuskesehatan gigi dan mulut pada murid-murid kelas I, II, dan III Sekolah Dasaryang berada di sekitar Klinik Kerja Mahasiswa FKG Unpad dengan melihatprevalensi karies dan indeks def-nya. Jenis penelitian ini adalah deskriptif.Sampel penelitian sebanyak 333 orang murid, yaitu murid-murid kelas I, II, danIII dari 4 buah Sekolah Dasar diambil secara acak, yang berlokasi di sekitar klinikkerja mahasiswa FKG Unpad. Hasil penelitian menunjukkan prevalensi kariesadalah sebesar 99,9% yang berarti hampir semua anak pada penelitian inimenderita karies, sedangkan indeks def adalah 10,2 artinya pada setiap anakyang diperiksa terdapat 10,2 gigi yang mengalami karies, ditambal, dan sudahdicabut atau diindikasikan untuk pencabutan. Hal ini menunjukkan bahwakeadaan kesehatan gigi dan mulut murid-murid kelas I, II, dan III Sekolah Dasaryang berada di sekitar klinik kerja mahasiswa FKG Unpad adalah buruk.Kata kunci : karies, prevalensi,indeks def
PREVALENSI KARIES DAN INDEKS d e f PADA MURID-MURID KELAS I, II, DAN III SEKOLAH DASAR YANG BERADA DI SEKITAR KLINIK KERJA MAHASISWA FAKULTAS KEDOKTERAN GIGI UNPAD Sufiawati, Irna; Setiani Dewi, Tenny; Aripin, Dudi
Sosiohumaniora Vol 4, No 2 (2002): SOSIOHUMANIORA, JULI 2002
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/sosiohumaniora.v4i2.5261

Abstract

Penelitian ini bertujuan untuk mengetahui gambaran umum tentang status kesehatan gigi dan mulut pada murid-murid kelas I, II, dan III Sekolah Dasar yang berada di sekitar Klinik Kerja Mahasiswa FKG Unpad dengan melihat prevalensi karies dan indeks def-nya. Jenis penelitian ini adalah deskriptif. Sampel penelitian sebanyak 333 orang murid, yaitu murid-murid kelas I, II, dan III dari 4 buah Sekolah Dasar diambil secara acak, yang berlokasi di sekitar klinik kerja mahasiswa FKG Unpad. Hasil penelitian menunjukkan prevalensi karies adalah sebesar 99,9% yang berarti hampir semua anak pada penelitian ini menderita karies, sedangkan indeks def adalah 10,2 artinya pada setiap anak yang diperiksa terdapat 10,2 gigi yang mengalami karies, ditambal, dan sudah dicabut atau diindikasikan untuk pencabutan. Hal ini menunjukkan bahwa keadaan kesehatan gigi dan mulut murid-murid kelas I, II, dan III Sekolah Dasar yang berada di sekitar klinik kerja mahasiswa FKG Unpad adalah buruk. Kata kunci : karies, prevalensi,indeks def
Herbal-induced Stevens-Johnson syndrome with oral involvement and management in an HIV patient Suniti, S.; Sufiawati, Irna
Dental Journal (Majalah Kedokteran Gigi) Vol 51, No 3 (2018): (September 2018)
Publisher : Faculty of Dental Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.31 KB) | DOI: 10.20473/j.djmkg.v51.i3.p153-157

Abstract

Background: Stevens-Johnson syndrome (SJS) is an immune complex-mediated hypersensitivity reaction affecting the skin and mucous membranes. Patients infected with human immunodeficiency virus (HIV) are at increased risk of developing SJS which is predominantly caused by an adverse reaction to medications, including herbal varieties. In recent years, the consumption of herbal medicines has increased, while their safety remains a matter for investigation. Purpose: The purpose of this case report is to explain the occurrence of SJS caused by herbal medicine. Case: A 43-year-old male patient with body-wide skin erosion was referred to the Department of Oral Medicine and subsequently diagnosed with Stevens-Johnson syndrome due to his consumption of a herbal medicine containing zingiber rhizoma, coboti rhizoma, asari herbal and epimedi. The patient’s chief complaints included difficulty when opening the mouth, dysphagia and excessive production of saliva continuously contaminated with blood and sputum. Extraoral examination showed a sanguinolenta crust on the lips. Intra oral examination of oral mucous showed erosive lesions with bleeding and pain. A HIV test performed at a Clinical Pathology Laboratory was positive for antibodies against HIV with a CD4 cell count of 11 cells/ml. Case management: Treatment consisted of the administering of NaCl 0.9 %, hydrocortisone 0.1% and Chlorhexidine digluconate 0.12% for 12  days. Conclusion: SJS can be caused by herbal medicine and it is essential to be aware of the latter’s potential adverse effects, especially in immunocompromised patients. Symptomatic management of oral lesions should be planned as an early intervention in order to decrease morbidity and mortality in SJS patients.
Noma management in a child with systemic lupus erythematosus Sufiawati, Irna; Sari, Asri Arum; Setiabudiawan, Budi; Gunadi, Rahmat
Dental Journal (Majalah Kedokteran Gigi) Vol 43, No 1 (2010): (March 2010)
Publisher : Faculty of Dental Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (476.055 KB) | DOI: 10.20473/j.djmkg.v43.i1.p6-10

Abstract

Background: Noma, also known as cancrum oris, is an orofacial gangrene, which during its fulminating stage causes progressive and mutilating destruction of the infected tissues. The disease occurs mainly in children with malnutrition, poor oral hygiene and debilitating concurrent illness. Purpose: The aim of this paper was to report a unique case of noma associated with systemic lupus erythematosus in an 8-year-old boy. Case: An 8-year-old boy referred to Oral Medicine Department complaining about an ulcer at the left corner of his mouth for 1 month, painful and difficulty in opening the mouth. The patient was diagnosed systemic lupus erythematosus since 14 months before and had been given immunosuppressive therapy. The patient was also diagnosed severe malnutrition. Haematologic investigations revealed anemia. Case management: Panoramic radiography was performed to check for dental or periodontal foci of infection, but no abnormalities were present. The microbiology examination revelaed Fusobacterium necrophorum, Staphylococcus aureus, and Klabsiella. The patient has been treated with oral irrigation using hydrogen peroxide, saline and 0.2% chlorhexidine, thus helped to slough the necrotic tissue. Oral antibiotics and analgesics were prescribed. The patient was admitted to hospital under the care of a pediatrician, allergy and immunology specialist, and a nutritionist. The result of the comprehensive disease management showed that the lesion healed completely, but leaving a scar on his corner of the mouth. Its physical effects are permanent and may require reconstructive surgery to be repaired by oral surgeon. Conclusion: Noma is not a primary disease, there are various predisposing factors usually precede its occurrence. The management of noma requires a multidisciplinary approach.Latar Belakang: Noma, dikenal sebagai cancrum oris, adalah gangren pada daerah orofasial, yang menyebabkan kerusakan progresif dari jaringan yang terinfeksi. Penyakit ini terjadi terutama pada anak dengan gizi buruk, kesehatan mulut yang buruk dan penyakit yang melemahkan. Tujuan: Makalah ini bertujuan untuk melaporkan sebuah kasus noma yang unikpada seorang anak laki-laki berusia 8 tahun yang menderita lupus eritematosus sistemik. Kasus: Seorang anak laki-laki 8 tahun dirujuk ke Bagian Ilmu Penyakit Mulut, mengeluh adanya luka di sudut mulut sebelah kiri yang telah diderita selama 1 bulan, terasa sangat sakit dan sulit membuka mulut. Pasien didiagnosis lupus eritematosus sistemik sejak 14 bulan sebelumnya dan telah diberikan terapi imunosupresif. Pasien juga didiagnosis menderita malnutrisi yang berat. Pemeriksaan hematologi menunjukkan pasien menderita anemia. Tatalaksana kasus: Radiografipanoramik dilakukan untuk memeriksa fokus infeksi dental atau periodontal, tetapi tidak ditemukan adanya kelainan. Pada pemeriksaan mikrobiologi ditemukan adanya Fusobacterium necrophorum, Staphylococcus aureus, dan Klabsiella. Perawatan pada pasien meliputi irigasi pada daerah gangren dengan hidrogen peroksida, larutan salin dan klorheksidin 0,2% untuk membersihkan jaringan nekrotik. Pasien juga diberikan antibiotik dan analgesik. Pasien dirawat di rumah sakit di bawah perawatan dokter spesialis anak, dokter spesialis alergi imunologi, dan ahli gizi. Hasil penatalaksanaan penyakit secara komprehensif memperlihatkan adanya penyembuhan, tetapi meninggalkan jaringan parut pada sudut mulutnya. Kelainan fisik tersebut bersifat permanen dan memerlukan pembedahan rekonstruktifoleh dokter gigi spesialis bedah mulut. Kesimpulan: Noma bukanlah penyakit primer, terdapat berbagai faktor predisposisi yang biasanya mendahului terjadinya penyakit tersebut. Pengelolaan noma memerlukan pendekatan multidisiplin.
Seroprevalence of Herpes Simplex virus types 1 and 2 and their association with CD4 count among HIV-positive patients Sufiawati, Irna; Widyaputra, Sunardhi; Djajakusumah, Tony S.
Dental Journal (Majalah Kedokteran Gigi) Vol 45, No 2 (2012): (June 2012)
Publisher : Faculty of Dental Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.67 KB) | DOI: 10.20473/j.djmkg.v45.i2.p114-120

Abstract

Background: Herpes simplex virus (HSV) is a common cause of viral opportunistic infections among HIV-positive patients. Frequent, more severe and prolonged episodes of recurrent HSV infection can be a source of significant morbidity and mortality among HIV-positive patients with advanced immunosuppression, reflected by low CD4 count. However, conflicting results have also been reported. Purpose: The aim of this study was to investigate the seroprevalence of HSV type 1 (HSV-1) and type 2 (HSV-2) in HIV-positive patients compare with the rate in HIV-negative patients, and to evaluate their association with CD4 count. Methods: A cross sectional study was conducted among 145 subjects consisting of 80 HIV-positive and 65 HIV-negative patients attending the top referral hospital in Bandung, West Java, Indonesia. The serum obtained was assayed for the presence of HSV-1 and HSV-2 IgG antibodies using ELISA kits. Data were analyzed using a Chi-square test, t-tests and analysis of variance (ANOVA). Results: There were no significant differences in HSV-1 seroprevalence between HIV-positive patients (71%) and HIV-negative patients (66%). HSV-2 seroprevalence was significantly higher in HIV-positive patients (30%) than HIV-negative patients (5%). The titers of HSV-1 IgG antibodies in HIV-positive patients (mean 24.63 ± 19.06 IDU) were significantly lower than those of HIV-negative patients (mean 44.62 ± 33.22 IDU). In contrast, HSV-2 IgG antibody titers in HIV-positive patients (mean 13.31 ± 20.28 IDU) were significantly higher than HIV-negative patients (mean 4.42 ± 10.99 IDU). There was no significant correlation between HSV-1 and HSV-2 seropositivity and CD4 count among HIV-positive patients. However, most of HSV-2 seropositive patients had CD4 count < 200 cells/mm3. Conclusion: Seroprevalence of HSV-1 and HSV-2 among HIV-positive patients was high with no correlation with CD4 count.Latar belakang: Herpes simplex virus (HSV) adalah penyebab infeksi virus oportunistik yang paling umum pada pasien HIVpositif. Infeksi HSV rekuren yang sering terjadi, lebih berat, dan episode yang berkepanjangan dapat menjadi penyebab morbiditas dan mortalitas yang signifikan pada pasien HIV-positif dengan imunosupresi lanjut, ditandai dengan jumlah CD4 yang rendah. Namun, hasil yang bertentangan juga telah dilaporkan. Tujuan: Penelitian ini bertujuan untuk mengetahui seroprevalensi HSV tipe 1 (HSV-1) dan tipe 2 (HSV-2) pada pasien HIV-positif dibandingkan dengan pasien HIV-negatif, dan untuk mengevaluasi hubungannya dengan jumlah CD4. Metode: Penelitian potong lintang ini dilakukan pada 145 subjek yang terdiri dari 80 pasien HIV-positif dan 65 pasien HIV-negatif yang berkunjung ke rumah sakit pusat rujukan di Bandung, Jawa Barat, Indonesia. Antibodi IgG HSV-1 dan HSV-2 di dalam serum diperiksa dengan menggunakan ELISA. Data dianalisis dengan uji Chi-square, t-test dan ANOVA, nilai p < 0.05 dianggap signifikan secara statistik. Hasil: Seroprevalensi antibodi IgG HSV-1 pada pasien HIV-positif (71%) tidak berbeda secara signifikan dengan pasien HIV-negatif (66%). Namun, seroprevalensi HSV-2 secara signifikan lebih tinggi pada pasien HIV-positif (30%) dibandingkan dengan pasien HIV-negatif (5%). Titer antibodi IgG HSV-1 pada pasien HIV-positif (mean 24.63 ± 19.06 IDU) secara signifikan lebih rendah dibandingkan pasien HV-negatif (mean 44.62 ± 33.22 IDU). Sedangkan, titer antibodi IgG HSV-2 pada pasien HIV-positif (mean 13.31 ± 20.28 IDU) secara signifikan lebih tinggi dibandingkan pasien HIV-negatif (mean 4.42 ± 10.99 IDU). Tidak ada hubungan yang signifikan antara seropositivitas HSV-1 dan -2 dengan jumlah CD4. Namun, sebagian besar pasien seropositif HSV-2 memiliki jumlah CD4 < 200 sel/mm3. Kesimpulan: Seroprevalensi HSV-1 dan HSV-2 pada pasien HIV-positif adalah tinggi, tetapi tidak berkorelasi dengan jumlah CD4.
Characteristic patients with oral mucositis receiving 5-FU chemotherapy at Hasan Sadikin Hospital Bandung Fatimah, Syarifah; Sufiawati, Irna; Wijaya, Indra
Padjadjaran Journal of Dentistry Vol 28, No 3 (2016): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.735 KB) | DOI: 10.24198/pjd.vol28no3.13695

Abstract

Introduction: Oral mucositis is an inflammatory reaction of oral mucous membrane that often appears in cancer patients due to the chemotherapeutic agents, such as 5-fluorouracil (5-FU). The aim of this study was to describe the characteristic patients who receive 5-FU and had oral mucositis. Methods: This study was conducted on 41 patients with cancer receiving 5-FU chemotherapy at Dr Hasan Sadikin Hospital Bandung. The data was retrieved through interviews to find out patient’s characteristic; nutritional status examination by using body mass index measurement; and oral examination. Severity level was determined by using National Cancer Institute’s Common Toxicity Criteria scale, and the level of pain was measured by Numeric Pain Intensity Rating scale. Results: This research have shown 60,98% patient with cancer had received 5-FU chemotherapy treatment, and 44% with poor nutritional status (underweight). Oral mucositis was only found at non-keratinised mucous. The finding of this study was patients that receiving 5-FU chemotherapy treatment diagnosed with oral mucositis was on the 1st stadium (52%) and the 2nd stadium (44%) with the level of pain was on the mild level (48%) and moderate level (32%).Conclusion: Oral mucositis was found on patients with cancer that received 5-FU chemotherapy with a variety of characteristics, nutritional statuses, locations, levels of severity and pain.
Successful treatment of herpes simplex-associated erythema multiforme with a combination of acyclovir and prednisone Muryah, Arny E.; Sufiawati, Irna
Journal of Dentomaxillofacial Science Vol 2, No 3 (2017): (Available online: 1 December 2017)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (658.363 KB) | DOI: 10.15562/jdmfs.v2i3.484

Abstract

Objective: Erythema Multiforme (EM) is an acute mucocutaneous hypersensitivity reaction triggered by certain infections and medications. EM induced by virus infection termed as Herpes- associated Erythema Multiforme (HAEM). The use of corticosteroids for treating HAEM has been a long debate issue. The aim of this case report is to present a patient with HAEM who was successfully treated with acyclovir combined with prednisone.Methods:A 31-years-old female, presented with a complaint of pain and diffuse ulcers in mouth. The patient reported recurrent episode of the ulcers of the mouth during the last two years. On extra oral examination, lips were crusted and bleeding. Intraoral examination revealed multiple diffuse ulcerations on mucosa. Nolesions were seen in other part of the body. Laboratory investigation revealed normal complete blood count and positive HSV-1 serology. The patient was diagnosed as HAEM.The patient was treated with acyclovir (1000 mg/day) and prednisone (10mg/day), topical mixture corticosteroid, chlorhexidine gluconate 0.2% and multivitaminduring seven days.Results:All lesions healed without any further clinical sequelae within 7 days.The clinical success of corticosteroids as effective anti-inflammatory agents is largely attributed to their ability to reduce the expression of pro-inflammatory genes, help to maintain vascular integrity and decrease the expression of leukocyte adhesion molecules.Conclusions:The addition of prednisone to acyclovir for HAEM resulted in a significant reduction of clinical signs and symptoms during the first week. The combination of acyclovir and corticosteroids may play an important role in the standard care for HAEM.
Evaluation of antibacterial activity and acute toxicity of pomegranate (punica granatum l.) seed ethanolic extracts in swiss webster mice Setiadhi, Riani; Sufiawati, Irna; Zakiawati, Dewi; Hidayat, Wahyu; Firman, Dani R.; Nur’aeny, Nanan
Journal of Dentomaxillofacial Science Vol 2, No 2 (2017): (Available online: 1 August 2017)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v2i2.536

Abstract

Objective: To evaluate the safety of a pomegranate seeds ethanolic extract in Swiss Webster mice.Material and Methods: Pomegranate seed’s ethanolic extracts were evaluated for minimum inhibitory concentration against streptococcus sanguis ATCC 10556, using microdilution method through 96-wells microplate. In acute toxicity test, 12 females and 12 males Swiss Webster mice weighing 20–30 grams were divided into four groups, each consisting of 3 females and 3 males. Three groups were orally given of sample with concentrations 0.2% equivalent to 40 mg/kg, 0.4% equivalent to 80 mg/kg, and 0.8% equivalent to 160 mg/kg, while the control group was given distilled water. Observations were made at 30, 60, and 90 minutes, for 24 hours and 7 days.Results: The MIC against Streptococcus sanguis was on 2000 ppm concentration and until 24 hours observation no lethal effect occurred on the mice, but at the 7 days observation in the group of 0.8% per kilogram body weight, the lethal effect occurred at one mice.Conclusion: The ethanolic extract of pomegranate seeds has antibacterial effect and no acute systemic toxicity, which can be considered safe on the use as oral topical solution since the toxic dose is greater than 160 mg/kg of body weight.
Inhibition growth of pomegranate seeds extract against streptococcus sanguis: the cause of recurrent aphthous stomatitis Setiadhi, Riani; Sufiawati, Irna; Zakiawati, Dewi; Hidayat, Wahyu; Firman, Dani R.; Nur’aeny, Nanan
Journal of Dentomaxillofacial Science Vol 2, No 1 (2017): (Available online: 1 April 2017)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v2i1.452

Abstract

Objective : Pomegranate (Punica granatum L.) seeds contain high of phytonutrients and phytochemicals, rich in polyphenol antioxidants namely tannins and flavonoids which also have antibacterial activity. Streptococcus sanguis is a bacterium known as one of the factors causing Recurrent Aphthous Stomatitis (RAS). To examine the potential antibacterial of Pomegranate seeds against Streptococcus sanguis.Material anda Methods : In vitro study of Pomegranate seed were extracted with maceration method using 70% ethanol as the solvent to obtain stable extract, continued with phytochemical screening against phenolic, flavonoids, alkaloids, steroids, triterpenoid, saponins and tannins.  The extract was evaluated for Minimum Inhibitory Concentration and Minimum Bactericide Concentration against Streptococcus sanguis ATCC 10556, using microdiluted method through 96 wells microplate. Results : Chlorhexidine was used as positive control while 70% ethanol was used as solvent as well as negative control. Phytochemical screening gave positive results for phenolics, flavonoids, steroids, saponins and tannins. Microdilution test showed the concentration of 500 ppm as MIC and MBC value at 2,000 ppm.Conclusion : Pomegranate seeds extract have a growth inhibitory against Streptococcus sanguis with MIC value of 500 ppm and 2,000 ppm as MBC.
Herpes Labialis and Oral Candidiasis in HIV-infected intravenous drug users with poor hematologic status Sufiawati, Irna; Sasanti, Harum
Padjadjaran Journal of Dentistry Vol 20, No 3 (2008): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1479.773 KB) | DOI: 10.24198/pjd.vol20no3.14125

Abstract

Hematologic abnormalities are common in HIV-infected patient, particularly in individuals with more advanced HIV disease. Hematologic abnormalities and their association with HIV-associated oral lesions had been reported. Intravenous drug use has been associated with increased oral lesions too. We reported a case of oral lesions in a 24 years old man HIV-infected intravenous drug users. Poor hematologic status is a risk factor of Oral Candidiasis in HIV-infected person with clinical features appear generally. But the clinical feature of Herpes Labialis is not usually because of his poor hematologic status. It’s concluded that poor hematologic status and transmission of HIV through contaminated needlestick are the high-risk factors of oral lesions and appear not usually clinical features in ODHA. Correction of these hematologic abnormalities and appropriately management of oral lesions can minimize the severity and increase the better quality of life patient.