Articles

POTENSI BUAH NANGKA (Artocarpus heterophyllus L) SEBAGAI ANTIDIABETES IN VITRO Khairina, Khairina; Suhartono, Eko; Biworo, Agung
Berkala Kedokteran Vol 11, No 2 (2015): September 2015
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i2.142

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Artocarpus species have been used by traditional medicine of Indonesian. It can be useful as anti-bacterial, anti-diabetic, anti-inflammatory, antioxidant and anti-helmintics. The present study was aimed to test the inhibitory glycated hemoglobin potency of aqueous extract of Jackfuit. This study is a quasi experimental research with non randomized method post test-only group design, which using a model reaction of two groups : extract jackfruit as the test group and glikazid as the control group, with each concentration of 10%, 20%, 30%. Potential inhibitor of glycated hemoglobin jackfruit as determining the amount of IC50. From this research  got IC50 of jackfruit extracts is 56,43% (r=0,999) whereas for glikazid of 17.268 (r = 0.989). The value of r indicates a positive relationship between the concentration and the inhibitor glycated hemoglobin potential. These results indicate that the extract of Jackfruit has potential as an inhibitor glycated hemoglobin. Keywords: glycated hemoglobin,  jackfruit, Artocarpus heterophllus L, glikazid.
Obstetrical and Non-Obstetrical Factors toward Uterine Prolapse Occurrence in Ulin General Hospital Banjarmasin on Januari – December 2017 Putra, Yohanes Adhitya Prakasa Sukoco; Suhartono, Eko; Budinurdjaja, Pribakti
Berkala Kedokteran Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v15i1.6121

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Abstract: Uterine prolapse is a gynecological disease in women that emerge patients physically and psychologically. Uterine prolapse is defined as an uterus herniation inside or outside vagina as the result of the ligament and fascia failure that retain the uterus in its actual place. This research was to identify obstetrical and non-obstetrical factors in uterine prolapses occurrence in Ulin General Hospital Banjarmasin on period January until December 2017 using case control approach. The total sample was 80 medical record samples, which divided into 40 medical record samples of patient with uterine prolapse and 40 medical record samples of patient without the occurrence of uterine prolapse. The results using chi square analysis obtained non-obstetrical factors: age >60 years old (OR 6.67: 95%CI 2.44-18.21), BMI > 30 (OR 3.10: 95%CI 1.24-7.71), menopause (OR 21.00: 95%CI 6.11-72.18); and non-obstetrical factors: parity >4 / multiparity (OR 13.78: 95%CI 4.71-40.28), macrosomia (OR 7.15: 95%CI 2.65-19.34), vaginal delivery (OR 28.78: 95%CI 7.41-111.79). The results of logistic regression obtained non-obstetrical factors: age > 60th (Exp B 4.21 and sig. 0.004), menopause (Exp B 1.12 and sig. 0.001), and multiparity (Exp B 2.35 and sig. 0.016). The results of this analysis obtained that obstetrical and non-obstetrical factors were related to uterine prolapse occurrence, and the dominant factor was age > 60 years old, so it could be concluded that there was significant factor between obstetrical and non-obstetrical factors on uterine prolapse occurrence in Ulin General Hospital Banjarmasin. Keywords: uterine prolapse, obstetrical factor, non-obstetrical factor
FILTRASI CAMPURAN PASIR DAN AMPAS TAHU KERING SEBAGAI ADSORBEN LOGAM BESI DAN MANGAN PADA AIR GAMBUT Pratiwi, Nadia Eka; Husaini, Husaini; Suhartono, Eko
Jurnal Berkala Kesehatan Vol 1, No 2 (2016): JURNAL BERKALA KESEHATAN
Publisher : Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (668.003 KB) | DOI: 10.20527/jbk.v1i2.3153

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Potensi air gambut di Kalimantan sebagai air  baku yang berlimpah tidak secara langsung dapat digunakan untuk keperluan sehari-hari seperti air minum, mandi dan mencuci. Kecamatan Gambut dan Kabupaten Hulu Sungai Selatan memiliki kualitas air gambut yang ekstrim yaitu derajat keasaman pH antara 3,7 – 4,3, kandungan zat organik tinggi dengan nilai KMnO4 antara 38-280 mg/l, serta kadar logam terlarut  Fe antara 0,45-5,96 mg/l. Kandungan logam besi dan mangan terlarut yang tinggi dapat mempengaruhi kehidupan biota, sumber daya dan kenyamanan ekosistem perairan. Tujuan Penelitian ini untuk menganalisis kemampuan rancang media penyaring campuran pasir dan ampas tahu kering dalam berbagai variasi berat dan waktu kontak untuk menurunkan kadar logam besi dan mangan pada air gambut. Penelitian ini menggunakan metode quasi eksperimental ( tidak dilakukan randomisasi) dengan post test group design tanpa kelompok kontrol. Media filter terdiri atas pasir dan ampas tahu kering dengan variabel bebasnya yaitu waktu kontak dan berat penjerap. Data dianalisis menggunakan uji Anova dua arah, kemudian dilanjutkan dengan uji Post Hoc. Uji Anova dua arah menunjukkan hubungan yang signifikan dan terdapat interaksi pada variabel waktu kontak dan berat penjerap dalam menurunkan kadar besi dan logam di dalam air gambut (p<0,05). Kesimpulan penelitian ini yaitu terdapat hubungan signifikan dalam menurunkan kadar besi dan mangan dilihat dari waktu kontak dan berat penjerap.
Daya Larut Ekstrak Etanol Daun Kembang Bulan (Tithonia diversifolia) Terhadap Batu Ginjal Kalsium Secara In Vitro Triyasmono, Liling; Suhartono, Eko
JURNAL PHARMASCIENCE Vol 2, No 1 (2015): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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Abstract

Abstrak            Telah dilakukan penelitian tentang daya larut ektrak etanol daun kembang bulan (Tithonia diversifolia) terhadap batu ginjal kalsium secara in vitro. Identifikasi flavonoid dilakukan dengan KLT menghasilkan senyawa yang terkandung adalah jenis flavon, sedangkan uji kualitatif batu ginjal dengan difraktometer sinar X dan FTIR menunjukkan bahwa batu ginjal yang digunakan adalah jenis kalsium oksalat. Ekstrak dibuat dengan 3 konsentrasi berbeda yaitu 0,125%, 0,25%, dan 0,5%. Batu ginjal kemudian dimasukkan sebanyak 100 mg ke dalam masing-masing konsentrasi dan diinkubasi selama 6 jam (37oC). Hasil filtrat didestruksi dan diukur kadar kalsium menggunakan spektrofotometer serapan atom pada l 422,7 nm. Hasil pengukuran rata-rata konsentrasi kalsium yang terlarut dalam ekstrak etanol pada konsentrasi 0,125%, 0,25%, dan 0,5% adalah 0,2893 ppm, 0,8809 ppm, dan 0,0554 ppm. Hasil uji  Kruskal-Wallis diperoleh (nilai sig sebesar 0,027 &lt; 0,05) dan disimpulkan bahwa konsentrasi kalsium terlarut dalam masing-masing konsentrasi ekstrak etanol yang dibuat berbeda signifikan. Hasil penelitian menunjukkan bahwa ekstrak etanol daun Kembang Bulan dapat melarutkan batu ginjal kalsium secara in vitro. Konsentrasi 0,25% memiliki daya larut batu ginjal kalsium in vitro yang paling tinggi. Kata kunci:    Batu ginjal kalsium, Kembang Bulan (Tithonia diversifolia), daya larut ekstrak etanol, spektrofotometer serapan atom AbstractIn vitro solubility activity test of ethanol extract of mexican sunflower leaves (Tithonia diversifolia) on calcium kidney stone has been carried out. Identification of flavonoids by TLC showed that a compound contained is kind of flavon, while qualitative test of kidney stones by X-ray diffraction and FTIR showed that the kidney stone is  type of calcium oxalate. The variation of ethyl acetate fraction was made at concentration of 0.125; 0.25; 0.5 % (w/v). Each ethanol extract was added 100 mg of kidney stone and incubated for 6 hours at a temperature of 37oC. Filtrate is destructed and measured of calcium concentration was measured using atomic absorption spectrophotometer at l 422.7 nm. The average of result measurement of calcium concentration dissolved in ethyl acetate concentration of 0.125; 0.25; 0.5 % (w/v)  is 0.2893; 0.8809; and 0.0554 ppm. Based on Kuskal Wallis test, obtained (sig=0.027&lt;0.05). It can be concluded that the dissolved calcium concentration in each ethanolic extract were significantly different. Ethanolic exctract  0.25% has the largest ability in dissolving calcium kidney stones in vitro. Keywords:       Calcium kidney stones, Tithonia diversifolia, solubility, ethanolic extract, Atomic Absorbtion Spectroscopy 
Effect of Stenochlaena palustris extract on circulating endothelial cellsMarmota caligata induced fever Suhartono, Eko; Bakhriansyah, M.; Handayani, Rini
INDONESIAN JOURNAL OF PHARMACY Vol 21 No 3, 2010
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (169.899 KB) | DOI: 10.14499/indonesianjpharm0iss0pp166-170

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Fever is increased  temperature  regulation  of  the  body.  In  the  process  is according  indirect  which  increased  of  free  radicals,  as  anion  superoxide  (•O2) and  will  trigger  oxidative  stress  happened.  Oxidative stress will effect in endothelial damaged. A celluler marker of damage the endothelium is increased number of Circulating  Endothelial  Cells (CEC).  The  aim  of  this  research  is  to valuated the influence of watery plant kalakai extract (Stenochlaena palustris)to number  of  Circulating  Endothelial  Cells  in  Marmota  caligata had  been  fever  and to calculated the average of CEC. The research is true experimental study, with Posttest-Only with Control Group Design, with 2 control group and 5 treatments group  of  each  4  Marmota  caligata. The CEC is   measured  by  Hladovec  method. Data  was  analyzed  by  using  Kruskal-Wallis  test  with confidence  rate  at  95  %. The  analyzed  results  got  p  =  0.001  (p  &lt;  0.05)  means there  be  a  significant different  between  treatment  group.  From the  result, can  be  conclude  that  the present of watery  plant kalakai  extract is decreasing CEC in plasma of Marmota caligatafever induced.Key words: Fever, Circulating Endothelial Cells, Stenochlaena palustris
Potensi ADP dan Katalase dalam Ekstrak Air Lidah Buaya (Aloe vera) sebagai Antiinflamasi pada Model Tikus Luka Terkontaminasi Biworo, Agung; Budianto, Windy Yuliana; Agustina, Rismia; Suhartono, Eko
Jurnal Mutiara Medika Vol 13, No 1 (2013)
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Muhammadiyah Yogyakarta

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Abstract

Lidah buaya (Aloe vera) mengandung enzim antioksidan yang dapat menghambat kerja dari mediator inflamasi dan penghilang rasa sakit. Pada penelitian ini akan diukur aktivitas enzim antioksidan askorbat dependent peroksidase dan katalase ekstrak air Aloe vera serta potensinya sebagai antiinflamasi pada tikus yang mengalami luka terkontaminasi. Penelitian ini menggunakan rancangan post test only control group dengan simple random sampling pada 36 ekor tikus yang terbagi atas 2 kelompok, yaitu kelompok kontrol (P0)  dan perlakuan (P1) merupakan kelompok tikus dengan luka terkontaminasi yang diberikan balutan dengan menggunakan ekstrak air lidah buaya 0,2 mg/g BB. Hasil penelitian menunjukkan bahwa aktivitas enzim antioksidan askorbat dependent peroksidase dan katalase masing-masing 37,8 menit-1 dan 3,145 menit-1 dan rata-rata penurunan intensitas warna kemerahan dari eritema pada kelompok yang diberi ekstrak air lidah buaya (Aloe vera) lebih cepat daripada kelompok kontrol. Diismpulkan bahwa ekstrak air lidah buaya berpotensi sebagai antiinflamasi pada model tikus luka terkontaminasi. Aloe vera contained an antioxidant enzyme that can inhibit the work of the mediators of inflammation and pain. With this research, however, will be measured the antioxidant enzyme activity of ascorbic dependent peroxidase and catalase on water extract Aloe vera and its potential as an anti-inflammatory on rat model wound contaminated. This research uses the post test only control group with simple random sampling techniques, with 36 rats were divided into two groups, namely the control and treatment groups. The control group (P0) is a control group and treatment group (P1)  is a group of mice with wounds contaminated given the wrap by using water extracts of Aloe vera 0.2 mg/g BB. In this study it was concluded that the antioxidant enzyme activity of activity of ascorbic dependent and catalase each 37.8 seconds-1 minute-1 and 3,145. In addition, the decrease in intensity of redness of erythema on the group that was given a water extract of Aloe Vera (Aloe vera) is faster than the control group. It can be concluded that the water extract of Aloe vera as anti-inflammatory potential in a mouse model of contaminated wounds.
POTENSI JUS BUAH PARE (Momordica charantia L.) SEBAGAI PENGHAMBAT HEMOGLOBIN TERGLIKASI IN VITRO Widyanto, Muhammad Topan; Suhartono, Eko; Biworo, Agung
Jurnal Berkala Kedokteran Vol 11, No 1 (2015): Februari 2015
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v11i1.194

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Bitter gourd  (Momordica charantia) is a fruit that is potentially has the ability to inhibit glycated hemoglobin thus can reduce blood sugar level. The aim of this study is to test the potency of bitter gourd juice as a glycated hemoglobin inhibitor. This is a quasi experimental study with non randomized posttest-only with control group design method, using a reaction model of diabetes consisted of two groups; bitter gourd juice as the test group and gliclazide as the standard group, divided into 10%, 20%, and 30% concentration. IC50 value is used to determine the potency as a glycated hemoglobin inhibitor. The result of this study shows that the value of r = 0,990 with an IC50 value of 69,239%, whereas for glikazid 17,268%. The positive value of r indicates a positive relation between concentration and its potency as a glycated hemoglobin inhibitor. The result thus indicates that bitter gourd juice has a potency as a glycated hemoglobin inhibitor Keywords: glycated hemoglobin, bitter gourd (Momordica charantia), gliclazide
Perbedaan Kadar Advanced Oxidation Protein Products (AOPP) Ovarium Tikus Putih (Rattus norvegicus) yang Terpajan Kadmium dan Tidak Terpajan Kadmium Rahmadhani, Endah Ayu; Suhartono, Eko; Noor, Meitria Syahadatina
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.935

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Abstract: Cadmium ( Cd) is one of hazardous and  poisonous material, which is that every material because of the nature of concentration or amount either directly or indirectly, can pollute the environment, health, the life of human beings and other living creatures. Cadmium induces toxicity or giving rise to a toxic effect through its ability in the formation of various free radical. An increase of free radicals that excessive will trigger oxidative stress. Advanced Oxidation Protein Products (AOPP) is one of the makers of the occurrence of oxidative stress, derived from the influence of oxidative, stress carbonyl, and increasing the activity of inflammatory globally. This research is an experimental laboratoric the study was performed with 2 groups the treatment, first is  the control group P(0) that does not given exposure cd have been given 2 mL/day aquadest for 4 weeks, and the group exposure P(1), who is given exposure of  Cd with concentration  6 mg Cd/L given 2 mL/day for 4 weeks. The results showed average levels of AOPP in the control group P (0) was 5,319 ± 2,540 µM and  exposure group P(1) has an average of 9,360 ± 1,727 µM AOPP levels. Statistical analysis of the results of the Mann-Whitney shows that there is a meaningful difference between a group with a value of p = 0.000. Can be concluded there that effect of the difference of the formation a both group of AOPP, which in AOPP levels  exposure is higher than the control group. Keywords: cadmium, ovarium, Advanced Oxidation Protein Products, oxidative stress.  Abstract: Kadmium (Cd) merupakan salah satu bahan berbahaya dan beracun yaitu setiap bahan yang karena sifat, konsentrasi atau jumlah, baik secara langsung maupun tidak langsung, dapat mencemari lingkungan hidup, kesehatan, kelangsungan hidup manusia serta mahluk hidup lain. Kadmium menginduksi toksisitas atau menimbulkan efek toksik melalui kemampuannya dalam pembentukan berbagai radikal bebas. Peningkatan radikal bebas yang berlebihan akan memicu terjadinya stres oksidatif. Advanced Oxidation Protein Products (AOPP) merupakan salah satu tanda-tanda terjadinya stres oksidatif, yang berasal dari pengaruh oksidatif, stres karbonil, dan peningkatkan aktivitas inflamasi secara global. Penelitian ini bersifat studi eksperimental laboratorik yang dilakukan dengan 2 kelompok perlakuan, yaitu kelompok kontrol P(0) yang tidak diberi pajanan Cd hanya diberi akuadest sebanyak 2 mL/hari selama 4 minggu dan kelompok pajanan P(1) yang diberi pajanan Cd dengan konsentrasi 6 mg Cd/L yang diberikan sebanyak 2 mL/hari selama 4 minggu. Hasil penelitian menunjukkan rerata kadar AOPP pada kelompok kontrol P(0) adalah 5,319 ± 2,540 µM dan kelompok pajanan P(1) memiliki rerata kadar AOPP sebesar 9,360 ± 1,727 µM. Hasil analisis statistik Mann-Whitney menunjukkan bahwa terdapat perbedaan yang bermakna antara kelompok dengan nilai p = 0,000. Dapat disimpulkan terdapat pengaruh perbedaan pembentukan AOPP terhadap kedua kelompok, dimana kadar AOPP pada kelompok pajanan lebih tinggi dibanding kelompok kontrol. Kata-kata kunci: kadmium, ovarium, Advanced Oxidation Protein Products, stres oksidatif.
Efek Pajanan Kadmium (Cd) terhadap Aktivitas Katalase Darah Tikus Putih (Rattus norvegicus) Khairunanda, Nuryandi; Suhartono, Eko; Triawanti, Triawanti
Jurnal Berkala Kedokteran Vol 10, No 1 (2014): Februari 2014
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i1.926

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ABSTRACT: Cadmium (Cd) is a heavy metal compound which is often founded in the environment and food. It has a wide variety of negative effects on target exposed organs, such as blood. Cd increases the Reactive Oxygen Species (ROS) which will lead to an increase in catalase (CAT) activity. The aim of this study was to determine the effect of Cd exposure on CAT activity in the rat ovary (Rattus norvegicus). It was an experimental laboratory using 2 groups. Control group P (0) was given 2 mL aquadest and treatment group P (1) was given Cd with 1,2 x 10-2 mg daily for 4 weeks. The results showed that the mean of the activity of CAT in the control group P(0) was 0,382 + 0,225 μU/mg while in the treatment group P(1) was 0,458 + 0,393 μU/mg. The statistical analysis test using unpaired t test showed an insignificant differences between those two groups with p = 0,599 (p > 0,05). It can be concluded that Cd does not have effect on activity of CAT in the rats’ blood. Keywords: cadmium, catalase activity, oxydative stress..ABSTRAK: Kadmium (Cd) adalah suatu senyawa logam berat yang sering terdapat pada lingkungan dan makanan. Cd memiliki berbagai efek negatif pada organ target yang terpajan, salah satunya adalah darah. Mekanisme Cd untuk merusak jaringan yang terpajan adalah dengan meningkatkan Reactive Oxygen Species (ROS) yang akan menyebabkan peningkatan aktivitas katalase (CAT). Penelitian ini bertujuan untuk mengetahui efek pajanan Cd terhadap aktivitas CAT pada darah tikus putih (Rattus norvegicus). Penelitian ini bersifat laboratorik eksperimental yang dilakukan pada 2 kelompok, yakni kelompok kontrol P(0) yang diberi akuadest sebanyak 2 mL dan kelompok pajanan P(1) yang diberi Cd dengan dosis 1,2 x 10-2 mg setiap hari selama 4 minggu. Hasil penelitian didapatkan rerata pada kelompok kontrol P (0) sebesar 0,382 + 0.225 µU/mg dan pada kelompok perlakuan P(1) sebesar 0,458 + 0,393 µU/mg. Pada uji t tidak berpasangan didapatkan tidak ada perbedaan yang bermakna dari kedua kelompok dengan p = 0,037 (p < 0,05). Dapat disimpulkan bahwa Cd tidak memiliki efek pada aktivitas CATpada darah tikus putih. Kata-kata kunci: kadmium, aktivitas katalase, stres oksidatif.
Perbedaan Kadar Methylglyoxal (MG) Ovarium Tikus Putih (Rattus Norvegicus) Terpajan Kadmium dan Tidak Terpajan Kadmium Husna, Annisa Halida; Suhartono, Eko; Noor, Meitria Syahadatina
Berkala Kedokteran Vol 10, No 2 (2014): September 2014
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.956

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ABSTRACT: Cadmium (Cd) is a heavy metal nonessensial that can pollute the environment and if it is included into the food chain and fish or plant indirectly also tainted Cd. If fish or plant that is contaminated with Cd consumed persistently by human beings in a long time will accumulate in the body and be chronic toxic by changing structural also functional an organ of the ovary. Determine the level Cd toxic in the ovary with measures level of methylglyoxal (MG). This research using the ovaries of white rats age of 2-3 months. This research to know the difference in the levels of MG of rat ovaries exposed and unexposed Cd. This study is experimental laboratory on the two groups, the control group P(0) that are aquadest as much as 2 ml per day for 4 weeks an exposure group P(1) who is given a Cd with a concentration of 6 mg/L are given as much as 2 ml for 4 weeks. The research results obtained average in the control group P(0) of 0,005 and treatment group P(1) by 0,016. Then to test normality Shapiro-wilk, after a normal, then do a non parametric tests Mann-whitney and meaningful differences between the results obtained by the control group p<0,005. There is a meaningful difference between the control group MG level of P(0) with the treatment group P(1) where the presence of increased levels of MG on Cd exposure groups. Keywords: cadmium, methylglyoxal, ovarium, stress oksidatif ABSTRAK: Kadmium (Cd) adalah logam berat nonessensial yang dapat mencemari lingkungan dan jika masuk ke dalam rantai makanan maka ikan ataupun tanaman secara tidak langsung juga tercemar Cd. Jika ikan atau tanaman yang tercemar Cd dikonsumsi terus-menerus oleh manusia dalam jangka waktu lama akan terakumulasi di tubuh dan berakibat toksiksitas kronis dengan mengubah struktural juga fungsional dari organ ovarium. Untuk mengetahui tingkat toksiksitas Cd di dalam ovarium dengan mengukur kadar methylglyoxal (MG). Penelitian ini menggunakan ovarium tikus putih yang berumur 2-3 bulan. Tujuan penelitian untuk mengetahui perbedaan kadar MG ovarium tikus putih yang terpajan Cd dan tidak terpajan Cd. Penelitian laboratorik eksperimental dilakukan dengan 2 kelompok, yaitu kelompok kontrol P(0) yang diberi akuadest 2 ml setiap hari selama 4 minggu dan kelompok perlakuan P(1) yang diberi Cd konsentrasi 6 mg/L sebanyak 2 ml selama 4 minggu. Hasil penelitian didapatkan rerata kelompok kontrol 0.005 dan kelompok perlakuan P(1) 0.016. Data kemudian di uji normalitas Shapiro-Wilk menunjukan p=0,000 (p<0,005). Kemudian dilakukan uji non-parametrik Mann-Whitney p=0,000 (p<0,005). Dapat disimpulkan bahwa terdapat perbedaan bermakna kadar MG antara kelompok kontrol P(0) yang tidak terpajan Cd dengan kelompok perlakuan P(1) yang terpajan Cd. Kata-kata kunci: kadmium, methylglyoxal, ovarium, stress oksidatif
Co-Authors Adenan Adenan, Adenan Agianto Agianto, Agianto Agung Biworo AKHMAD RIZALI Amin Setyo Leksono Anindya, Anindya Anindya, Anindya Annisa Halida Husna, Annisa Halida Ari Yunanto Bahrul Ilmi Bambang Setiawan Basir Achmad Budinurdjaja, Pribakti Cahyadi, Wiji Denny Margono, Denny Denny P.N.H. Margono, Denny P.N.H. Dicky Andiarsa Djaka Sasmita, Djaka Dona Marisa, Dona Donna Marisa, Donna Edi Hartoyo Edyson, - Emma, Arrifah Noer Emmy Sri Mahreda Endah Ayu Rahmadhani, Endah Ayu Erliyanti, Emmi Fadily, Abdullah Fakhrur Razie Farizka Erianti, Farizka Fatah, Lutfhi Haekal, Anes Fikri Heny Arwati, Heny Husaini Husaini Husnul Khotimah Iskandar Iskandar Iwan Aflanie, Iwan Khairina Khairina, Khairina Liestiana Indriyati Liling Triyasmono, Liling M. Bakhriansyah, M. Maharani Laillyza Apriasari, Maharani Laillyza Mashuri Mashuri Mega, Vicky Pramudinta Meitria Syahadatina Noor Mohammad Bakhriansyah Muhammad Hafidz Maulana Setiawan, Muhammad Hafidz Maulana Muhammad Hendy Arizal, Muhammad Hendy Muhammad Rasyid Ridha Muhammad Rizky Tri Aditya, Muhammad Rizky Tri Muhammad Topan Widyanto, Muhammad Topan Nadia Eka Pratiwi, Nadia Eka Nasri, Novi Mustahdiati Nia Kania Niarsari Anugrahing Putri Novie Aprianti, Novie Nuryandi Khairunanda, Nuryandi Olivia Sari, Devi PAISAL PAISAL Pratama, Mohammad Rizki Fadhil Putera, Bayu Diertama Putra, Fadillah Alma Putra, Yohanes Adhitya Prakasa Sukoco Ratih Kumala Sari, Ratih Kumala RHA. Sahirul Alim, RHA. Sahirul Rinawati Rinawati Rini Handayani Rismia Agustina, Rismia Rizany, Ichsan Rizky Taufan Firdaus, Rizky Taufan Ruhullah, Mustofa Ruslan Muhyi, Ruslan Ruslan Ruslan Salamiah Salamiah Saldy Rizky Saputra, Saldy Rizky Santi, Eka Santosa, Purwanto Budi Sari, Nur Yulia Sartika, Eria Sartika, Eria Siti Juliati, Siti Thalib, Iskandar Thalib, Iskandar Thalib, Iskandar Triawanti Triawanti Utama, Adelia Anggraini Warih Anggoro Mustaqim, Warih Anggoro Wenda Fitriati Noor, Wenda Fitriati Widyamala, Erida Windy Yuliana Budianto, Windy Yuliana Wulandani, Wenny Yeni Wahyu Ulfarini, Yeni Wahyu Zoelkarnain Akbar, Izaak