Hermina Sukmaningtyas
Bagian Radiologi Fakultas Kedokteran Universitas Diponegoro/RS Dr. Kariadi Semarang, Jl. Dr. Sutomo 16-18 Semarang

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PENGARUH MEDIA KONTRAS IOPAMIDOL DOSIS TINGGI INTRAVASKULER TERHADAP KADAR KREATININ SERUM DAN GAMBARAN HISTOPATOLOGI TUBULUS GINJAL PADA TIKUS SPRAGUE-DAWLEY: UPAYA PROTEKSI DENGAN L-ARGININ Sukmaningtyas, Hermina; Trihadi, Djoko Untung
MEDIA MEDIKA INDONESIANA 2008:MMI Volume 43 Issue 3 Year 2008
Publisher : MEDIA MEDIKA INDONESIANA

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High dose intravascular iopamidol influence on serum creatinine level and histopatologic feature of kidney tubules in Sprague-Dawley rats: using L-arginine as protectionBackground: Iopamidol, a Low Osmolar Contrast Media (LOCM), has relatively less nephrotoxicity, but contrast media (CM) volume has role to develop acute renal failure even in healthy person. L-arginine as a natural precursor of nitric oxide might prevent contrast nephropathy. Objectives: To investigate effects of iopamidol on acute renal damage by observing serum creatinine level and acute renal necrosis and to assses the role of L-arginine to protect acute renal failure.Methods: This was a post test only control group design experimental study using 35 male, twelve weeks old Sprague-Dawley rats, weighing 200-350 g, allocated into seven groups. The control group (K), P1, P2, P3 were group given 1.8 ml iopamidol and P4, P5, P6 groups were given 8.4% (W/V) L-arginine personde twice a day, 5 ml each for 7 days before 1.8 ml iopamidol injection. Serum creatinine and histological examination were done to assess acute tubular necrosis with H&E staining observed on 24, 48, and 72 hour accordingly. Dose of iopamidol used was equal to 100 ml human dose. The difference of serum creatinine and acute tubular necrosis were analyzed by using ANOVA test.Results: There were no significant differences among groups on serum creatinine level (p=0.261). Acute tubular necrosis increased following iopamidol administration in 72 hour (P3) p=0.007, and pretreatment with L-arginin reduced necrosis in group P6 (p=0.008).Conclusions: Serum creatinine level was not different after administration of iopamidol and L-arginine. Iopamidol induce acute tubular necrosis, while L-arginine can prevent CM-induced nephropathy. Keywords: Iopamidol, serum creatinine, acute tubular necrosis, L-arginine ABSTRAK Latar belakang: Iopamidol, media kontras osmolalitas rendah mempunyai efek nefrotoksik relatif rendah, tetapi pemakaian dosis tinggi merupakan faktor resiko nekrosis tubuler akut. L-arginin, asam amino prekursor NO dan sebagai antioksidan dapat mencegah contrast-induced nephropaty.Tujuan: Mengetahui pengaruh iopamidol terhadap perubahan kadar kreatinin serum dan gambaran nekrosis tubuler akut, serta melihat pengaruh L-arginin terhadap penurunan kejadian contrast-induced nephropaty.Metode: Penelitian eksperimental sesungguhnya dengan rancangan post test only control group design pada tikus Sprague-Dawley jantan, sehat, umur 12 minggu, berat badan 200-350 g. Sebanyak 35 ekor tikus dibagi secara acak menjadi 7 kelompok. Kelompok K, tidak mendapatkan perlakuan, P1, P2, P3 diberi iopamidol 1,8 cc intravena. Kelompok P4, P5, P6 diberi L-arginin 8,4 w/v 2x sehari masing-masing 5 ml selama 7 hari, sebelum disuntik iopamidol 1,8 ml intravena. Kadar kreatinin serum dan pemeriksaan nekrosis tubuler akut diperiksa secara histopatologi dengan pengecatan H&E pada jam ke-24, jam ke-48, jam ke-72 sesuai dengan kelompok perlakuan. Dosis iopamidol setara dengan 100 ml pada dosis manusia. Perubahan kadar kreatinin serum dan nekrosis tubuler akut diuji dengan uji ANOVA.Hasil: Kadar kreatinin serum tidak berbeda di antara kelompok (p=0,261). Pemberian iopamidol menyebabkan nekrosis tubuler akut pada jam ke-72 (p=0,007), dan pemberian L-arginin menurunkan nekrosis tubuler akut pada jam ke-72 (p=0,008). Simpulan: Iopamidol dosis tinggi dapat menginduksi nekrosis tubuler akut pada keadaan tanpa resiko, dan pemberian L-arginin dapat mencegah contrast-induced nephropathy. Kadar kreatinin serum tidak berbeda setelah pemberian iopamidol maupun L-arginin.
DERAJAT SINDROMA DISTRES RESPIRASI PADA FOTO THORAX DAN DERAJAT ASFIKSIA PADA NEONATUS PREMATUR Ningrum, Farah Hendara; Sukmaningtyas, Hermina; Wahyuni, Mardiana
MEDIA MEDIKA INDONESIANA 2010:MMI VOLUME 44 ISSUE 1 YEAR 2010
Publisher : MEDIA MEDIKA INDONESIANA

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The degrees of respiratory distress syndrome from thorax X-ray and degrees of asphyxia in preterm neonatesBackground: Respiration Distress Syndrome (RDS) is a complication of prematurity lung disorder and common causes of premature neonatal morbidity. Clinically RDS provides signs of asphyxia that can be assessed with APGAR score. Chest X-ray can also diagnose and determine the degree of RDS radiologically. This study aims to find the relationship degree of RDS clinically with radiologically.Methods: Analytic observational study with cross-sectional design. The subjects were premature neonates with asphyxia in Kariadi General Hospital Semarang who had APGAR score and RDS on the standard Chest x-ray examination and selected using consecutive sampling method. The relationship between the RDS clinical degree based on APGAR score with radiological degrees tested with the Chi square test (X2) and Kendall tau-b. There were four grading for RDS. Chest x-ray images were interpretated by 2 expert radiologists independently and then Kappa value was evaluated.Results: There were 23 RDS cases consisted 12 severe, 8 moderate and 3 mild asphyxia cases. Radiologically showed grade I (9), grade II (5), grade III (5) and grade IV (4) neonates. Kappa value=1 (p<0.001). Chi square test (X2) showed clinical asphyxia degree was not significantly different with the degree of RDS on chest x-ray. Kendall tau-b correlation test showed a significant and moderate degree correlation (r=0.5; p=0.01).Conclusions: The degree of asphyxia in premature infants are in line with radiological images.ABSTRAKLatar belakang: Sindroma distres respirasi (SDR) yang bermanifestasi dalam bentuk asfiksia merupakan kelainan paru komplikasi prematuritas penyebab tersering morbiditas neonatus prematur. X-foto thorax membantu diagnosis SDR sekaligus menentukan derajat SDR. Penelitian ini bertujuan menilai hubungan derajat klinis SDR dengan derajat radiologi.Metode: Studi observasional analitik dengan rancangan cross-sectional. Subjek penelitian adalah neonatus prematur dengan asfiksia di RSUP Dr. Kariadi Semarang yang mempunyai skor APGAR serta mendapatkan pemeriksaan X-foto thoraks standar. Pemilihan subjek menggunakan metode consecutive sampling. Terdapat empat derajat SDR secara radiologis Hubungan antara derajat klinis SDR berdasarkan skor APGAR dengan derajat radiologis diuji dengan Chi square(X2) dan derajat korelasi dengan uji Kendall tau-b. Hasil X-foto thorax diinterpretasi terpisah oleh 2 ahli radiologi dan diuji Kappa. Hasil: Dijumpai 23 asfiksia neonatus prematur dengan SDR terdiri dari 12 kasus asfiksia berat, 8 kasus asfiksia sedang dan 3 kasus asfiksia ringan. Secara radiologis ditemukan SDR derajat I sebanyak 9, 5 derajat II, 5 derajat III dan derajat IV pada 4 neonatus. Nilai Kappa=1 (p<0,001). Derajat asfiksia secara klinis tidak berbeda bermakna dengan derajat radiologi SDR (Chi square(X2) p=0,007). Uji korelasi Kendall tau-b menunjukkan korelasi bermakna tingkat sedang (r=0,5; p=0,01) antara derajat asfiksia secara klinis dengan derajat radiologi SDR. Simpulan: Derajat asfiksia pada bayi prematur sejalan dengan derajat radiologik foto thorax pada SDR.
Correlations between osteoartritis grading in femorotibial joint (kellgren lawrence) with cartilage defects grading Permatasari, Yuliati; Zulqarnain, Nasirun; Sukmaningtyas, Hermina; Suntoko, Bantar
Indonesian Journal of Rheumatology Vol 8, No 2 (2016)
Publisher : Indonesian Rheumatology Association

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Abstract

Background : Osteoarthritis (OA) is the most common chronic rheumatic diseases that causing pain and disability. The imaging of knee OA were found in 15,5%  men and 12,7% women of Indonesia population. Radiography is still used as a standard modalities in assesing OA progression, and Kellgren-Lawrence scale (KL) is the most common measurement used byclinicians. Superficial cartilage degradation is the first sign of OA, the early detection of the superficial cartilage degradation is very important for diagnosis. Our study was established to assess the correlation between OA grading in femorotibial joint examined by standard Kellgren-Lawrence scale (KL) measurement with cartilage defects examined by ultrasound.Methods : Observational analytic study with cross sectional and consecutive sampling was performed. Rank Spearman test for correlation of OA grading, cartilage defect, BMI and joint malalignment. McNemar test for correspondence between the location of the narrowing of the femorotibial joint and location of cartilage defects.Result : Correlation of OA grading of femorotibial joints (KL) with cartilage defects grading on ultrasound resulted r =0.459, p<0.05; correlation of OA grading of femorotibial joints (KL) with BMI or joint malalignment resulted p>0,05; correlation of cartilage defect grading with BMI or joint malalignment also resulted p>0.05. McNemar test for location of the narrowing of thefemorotibial joint with location of cartilage defects on ultrasound resulted p = 1.00, k = 0.714. There was a significant positive correlation of OA grading of femorotibial joints (KL) with cartilage defects grading on ultrasound. There was no significant correlation between OA grading of femorotibial joints (KL) with BMI and joint malignment, and no significant correlationbetween cartilage defects grading with BMI and joint malalignment. There is a correspondence between the location of the narrowing of the femorotibial joint with location of cartilage defects on ultrasound.Conclusion: For assesing the grade of osteoartritis, cartilage defect grading and assesment by ultrasound can be used as an alternative to X-Ray KellgrenLawrence scale (KL) measurement.Keywords : femorotibial joint, cartilage defects grading, osteoartritis grading examination, BMI, joint malalignment.
KESESUAIAN METODE PENGUKURAN PERSENTASE LEMAK TUBUH SKINFOLD CALIPER DENGAN METODE BIOLECTRICAL IMPEDANCE ANALYSIS Wijayanti, Dwi Nina; Sukmaningtyas, Hermina; Fitranti, Deny Yudi
DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO ) Vol 7, No 2 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO )

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Latar Belakang: Pengukuran persentase lemak tubuh yang akurat merupakan hal yang diperlukan untuk memonitor lemak tubuh, obesitas dan untuk rencana pengaturan diet dalam program pelayanan kesehatan. Lemak tubuh memiliki hubungan dengan beberapa faktor risiko kesehatan. Bioelectrical Impedance Analysis dan Skinfold Caliper dapat memperkirakan persentase lemak tubuh. Kedua alat tersebut mudah, murah dan tidak invasif.Tujuan: Mengetahui kesesuaian Bioelectrical Impedance Analysis dengan Skinfold Caliper terhadap pengukuran persentase lemak tubuh pada wanita dewasa muda.Metode: Penelitian dilakukan terhadap 33 wanita dewasa muda dengan tinggi badan 155 ? 165 cm dan berat badan 45 ? 55 kg. Pada semua subyek dilakukan pengukuran lemak menggunakan Bioelectrical Impedance Analysis dan Skinfold Caliper pada 4 lokasi (trisep, bisep, subskapula dan suprailiaka). Data selanjutnya dianalisis menggunakan uji intraclass correlation coefficient (ICC) absolut agreement.Hasil: Pada pengukuran persentase lemak tubuh menggunakan Bioelectrical Impedance Analysis didapatkan rerata 20,31 ± 3,13 %, sedangkan Skinfold Caliper didapatkan 23,50 ± 1,51 %. Terdapat perbedaan antara pengukuran Bioelectrical Impedance Analysis dan Skinfold Caliper. Uji kesesuaian menunjukkan kesesuaian derajat sedang (ICC=0,42).Kesimpulan: Terdapat kesesuaian dengan derajat sedang antara pengukuran persentase lemak tubuh yang diukur menggunakan Bioelectrical Impedance Analysis dan Skinfold Caliper pada wanita dewasa muda.
KORELASI LOKASI PERDARAHAN INTRASEREBRAL DENGAN OUTCOME PASIEN STROKE HEMORAGIK Pradesta, Rizki Rudwi; Sukmaningtyas, Hermina; Pudjonarko, Dwi
DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO ) Vol 6, No 2 (2017): JURNAL KEDOKTERAN DIPONEGORO
Publisher : DIPONEGORO MEDICAL JOURNAL ( JURNAL KEDOKTERAN DIPONEGORO )

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Latar belakang Angka kejadian stroke meningkat tajam beberapa tahun kebelakang dan Indonesia menjadi negara dengan jumlah penderita stroke terbanyak di Asia. Stroke hemoragik intraserebral merupakan jenis kedua terbanyak dari pasien stroke setelah stroke iskemik. Outcome stroke dipengaruhi oleh banyak faktor antara lain GCS, volume perdarahan, lokasi perdarahan, perluasan intraventrikuler, dan adanya peningkatan waktu pembekuan darah. Lokasi perdarahan merupakan faktor yang berpengaruh kuat untuk memprediksi kefatalan kasus, letak lokasi perdarahan yang bervariasi menyebabkan lokasi perdarahan bisa dijadikan pembeda untuk menentukan tingkat keparahan prognosis pasien stroke hemoragik. Penilaian outcome  stroke dapat dinilai dengan menggunakan Barthel Index karena realibilitasnya yang cukup tinggi yaitu 0,95 dan dapat dilakukan dalam waktu singkatTujuan Mengetahui korelasi lokasi perdarahan intraserebral dengan outcome pasien stroke hemoragik.Metode penelitian ini merupakan penelitian Observasional Analitik dengan metode Belah Lintang. Subjek merupakan pasien yang terdaftar sebagai pasien Stroke Hemoragik di RSUP Dr. Kariadi Semarang tahun 2015-2016. Data yang dikumpulkan adalah data sekunder berupa skala nominal yang ditentukan dari hasil CT Scan lokasi perdarahan pasien dan data ordinal yang didapatkan dari hasil penilaian kuesioner Barthel Index. Uji statistik menggunakan uji korelasi Chi Square.Hasil Tidak terdapat korelasi antara lokasi perdarahan dengan outcome  pasien stroke hemoragik yang dihitung menggunakan Barthel Index dengan nilai p= 0.665 (bermakna bila p < 0,05).Kesimpulan Tidak terdapat korelasi antara lokasi perdarahan dengan outcome  pasien stroke hemoragik yang dihitung menggunakan Barthel Index pada penelitian kali ini.
Correlations between osteoartritis grading in femorotibial joint (kellgren lawrence) with cartilage defects grading Permatasari, Yuliati; Zulqarnain, Nasirun; Sukmaningtyas, Hermina; Suntoko, Bantar
Indonesian Journal of Rheumatology Vol 8 No 2 (2016)
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (434.65 KB)

Abstract

Background : Osteoarthritis (OA) is the most common chronic rheumatic diseases that causing pain and disability. The imaging of knee OA were found in 15,5%  men and 12,7% women of Indonesia population. Radiography is still used as a standard modalities in assesing OA progression, and Kellgren-Lawrence scale (KL) is the most common measurement used byclinicians. Superficial cartilage degradation is the first sign of OA, the early detection of the superficial cartilage degradation is very important for diagnosis. Our study was established to assess the correlation between OA grading in femorotibial joint examined by standard Kellgren-Lawrence scale (KL) measurement with cartilage defects examined by ultrasound.Methods : Observational analytic study with cross sectional and consecutive sampling was performed. Rank Spearman test for correlation of OA grading, cartilage defect, BMI and joint malalignment. McNemar test for correspondence between the location of the narrowing of the femorotibial joint and location of cartilage defects.Result : Correlation of OA grading of femorotibial joints (KL) with cartilage defects grading on ultrasound resulted r =0.459, p&lt;0.05; correlation of OA grading of femorotibial joints (KL) with BMI or joint malalignment resulted p&gt;0,05; correlation of cartilage defect grading with BMI or joint malalignment also resulted p&gt;0.05. McNemar test for location of the narrowing of thefemorotibial joint with location of cartilage defects on ultrasound resulted p = 1.00, k = 0.714. There was a significant positive correlation of OA grading of femorotibial joints (KL) with cartilage defects grading on ultrasound. There was no significant correlation between OA grading of femorotibial joints (KL) with BMI and joint malignment, and no significant correlationbetween cartilage defects grading with BMI and joint malalignment. There is a correspondence between the location of the narrowing of the femorotibial joint with location of cartilage defects on ultrasound.Conclusion: For assesing the grade of osteoartritis, cartilage defect grading and assesment by ultrasound can be used as an alternative to X-Ray KellgrenLawrence scale (KL) measurement.Keywords : femorotibial joint, cartilage defects grading, osteoartritis grading examination, BMI, joint malalignment.
Perbedaan Kualitas Gambar MRI 0,3 Tesla Antara Metode Grappa dan Metode Perubahan Nilai Parameter dengan Metode Rutin (Studi Pada Pemeriksaan MRI Vertebra Lumbal Potongan Sagital T2 FSE RSUD Prof. Dr. Margono Soekardjo Purwokerto Pada Pasien Dengan Lumbar Nurcahyo, Panji Wibowo; Suwondo, Ari; Sukmaningtyas, Hermina
Jurnal Imejing Diagnostik (JImeD) Vol 1, No 1: Januari 2015
Publisher : Poltekkes Kemenkes Semarang

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Abstract

Background : Artefact degrade image quality. Motion artefact can be minimized by reducing scan time. The use of GRAPPA and change the value of TR, NEX and phase enchoding can reduce scan time. This study aims to determine the difference between MRI image quality of the GRAPPA method and routine method with change the value Phase enc. Dir., FOV phase, TR, TE, NEX, concatenation, base resolution, phase resolution and bandwidth by routine method MRI examination of lumbar spine sagittal T2 FSE in Prof. Dr. Margono Soekardjo hospital in patients with lumbar disorders.Methods : Quasi experiments with equivalent posttest only control group design in 25 respondents were obtained in consecutive sampling. Each respondent was given three treatments with different method. Qualitative assessment was done on the MRI images results of the third treatment. Presence or absence of an overview assessment results HNP, spondylosis and degenerative disc analyzed with Cochran test while the level of clarity of the ligamentum flavum, thecal sac, intervertebral disc, vertebral body and the spinal cord was analyzed by Friedman test.Results : Cochran test produces a p value &gt;0,05, while the friedman test results were followed by post hoc analysis resulted p value &lt;0,05. The highest mean value rank is 3 with obtained of the routine method but has a scan time 326 seconds, the GRAPPA activation performed (mean rank 1) then the scan time can be reduced by 144 second and routine method with change the value of some parameters can reduce 150 second with a mean rank 2.Conclusion : There is no difference reveal HNP, spondilosis and degenerative disc ability between GRAPPA method and routine method with change the value of some parameters by routine methodProf. Dr. Margono Soekardjo hospital, but levels of clarity ligamentum flavum, thecal sac, intervertebra disc, corpus vertebra dan spinal cord is difference. Routine method Prof. Dr. Margono Soekardjo hospitalproduce images with the best quality, but has a maximum scan time.
THORAX MULTI-SLICE COMPUTER TOMOGRAPHY (MSCT) EXAMINATION TECHNIQUE IN THE CASE OF MEDIASTINUM TUMOR AT RADIOLOGY INSTALATION OF SEMARANG DISTRICT GENERAL HOSPITAL Mayasari, Ike; Sukmaningtyas, Hermina; Wibowo, Ardi Soesilo; Santjaka, Aris; Anwar, M. Choerul; Latifah, Leny
Proceedings of the International Conference on Applied Science and Health No 1 (2017)
Publisher : Proceedings of the International Conference on Applied Science and Health

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Background: Thorax Multi-slice computer tomography (MSCT) scan examination requires contrast medium to image the difference in density with the surrounding tissue. The contrast images is largely determined by the volume of contrast, injection rate and injection methods. Thorax CT scan is performed by slice thickness of 5-10 mm. Meanwhile, it should use the routine slice thickness of 10 mm. Slice thickness of 8-10 mm of coronal and sagittal images require reconstruction by thin slices of 1-1.5 mm and subsequently by applying 3D. Aims: This is to analyse the volume of contrast and slice thickness used in the examination of tumor mediastinum by thorax MSCT examination. Methods: This research used descriptive qualitative design with case study approach, described and explained systematically, related to the procedure of Thorax MSCT examination technique in the case of mediastinum tumor with 3 samples of 3 patient and assessment performed by three radiologist as respondents. Results: This study indicates the success of the use of proper contrast of 80 cc and slice thickness of 2-3 mm to observe lesions of mediastinal tumor. Conclusion: Thorax MSCT examination in the case of mediastinum tumor should use contrast 80 cc and slice thickness of 2-3 mm to observe lesions of mediastinal tumor and coronal and sagittal axial slices, because the sagittal slice can show the lymphadenopathy enlargement so that the mediastinum tumor is clearly visible. The print out or filming results should be included the MPR or 3D to show the presence or absence of bone destruction and metastases. 
OPTIMIZATION OF R-FACTOR AT GRAPPA PARALLEL ACQUISITION TECHNIQUE ON THE IMAGE INFORMATION T2 AXIAL BRAIN MRI Saifudin, Saifudin; Sukmaningtyas, Hermina; Indrati, Rini; Santjaka, Aris
Proceedings of the International Conference on Applied Science and Health No 1 (2017)
Publisher : Proceedings of the International Conference on Applied Science and Health

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Background: GRAPPA or Generalized Auto-calibrating Partially Parallel Acquisitions is a parallel acquisition technique which can reduce the scan time in MRI examination. Aims: This study aims to investigate the effect of the R-factor variation of GRAPPA on image anatomical information quality and to determine the optimization value of GRAPPA e-factor to fasten the scan time with acceptable image information quality. Methods: Eight respondents will perform T2 axial Brain MRI examination with various values of GRAPPA R-factor (1 to 7), evaluation was conducted with questionnaire which was given to 3 radiologists to assess the anatomical structure of the lateral ventricle, thalamus, caudate nucleus, lent form nucleus, internal capsule and background area. Data from respondents were then tested with Spearman test and Friedman test. Results: Statistics test showed that there was significant effect of GRAPPA parallel acquisition technique on the anatomical image information quality of T2 axial Brain MRI (p value of 0,001<0,05) and the correlation direction was negative, in which the higher the value of r-factor GRAPPA used, the lower the quality of anatomical image information. Based on the result of mean rank, image with optimal image anatomical information quality was image with GRAPPA R-factor of 1 (mean rank = 6.01), but image anatomical information quality with GRAPPA R-factor of 3 was acceptable with fast scan time (opinion of 75 % of all radiologists). Conclusion: R-factor at GRAPPA parallel acquisition technique could reduce scan time, but the higher the value of r-factor GRAPPA used, the lower the quality of image anatomical information. 
PEMBERIAN MAKANAN PENDAMPING ASI DENGAN PENAMBAHAN PEMBERIAN MINYAK, SANTAN, IKAN, DAN KACANG KACANGAN UNTUK MENINGKATKAN STATUS GIZI ANAK Wirawanni, Yekti; Puruhita, Niken; Sukmaningtyas, Hermina
JNH (Journal of Nutrition and Health) Vol 1, No 1 (2013): JOURNAL OF NUTRITION AND HEALTH
Publisher : Universitas Diponegoro

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ABSTRAKLatar belakang : Status gizi anak ditentukan oleh berbagai faktor, antara lain makanan pendamping ASI(MPASI) yang mengandung kalori dan protein yang cukup dan diberikan mulai umur 4 bulan. MPASI inisering diberikan dalam jumlah dan kualitas yang kurang, karena ketidaktahuan ibu tentang MPASI yangbergizi.Tujuan : Untuk melihat adanya perbedaan kandungan energi dan protein MPASI serta status gizi bayisebelum dan sesudah penyuluhan. Penyuluhan diberikan kepada ibu-ibu balita untuk meningkatkan kaloridan protein. Makanan pendamping ASI dengan menambahkan minyak, santan, ikan dan kacang-kacanganpada Makanan Pendamping ASI yang diberikan untuk anak.Metode: Rancangan penelitian ini adalah pre- and post-test design dengan sampel sebanyak 20 orang ibukeluarga nelayan yang menpunyai  anak usia 0-2 tahun. Pengumpulan data dilakukan dengan wawancaraberdasarkan kuesioner. Berat badan ditimbang dengan dacin, sedangkan panjang anak diukur denganmeteran pada saat posyandu. Status gizi anak dinilai dengan antropometri dengan menggunakan batasanz-score ? 2 SD dari buku WHO-NCHS. Uji statistik dengan Wilcoxon Signed rank test dengan batasankemaknaan 0,05.Hasil : Kandungan energi  MPASI rata-rata 312,8 kal/hari dan protein 9,69 gram/hari. Anak nelayan diRW I,II,III Kelurahan Bandarhardjo rata-rata berada dalam keadaan gizi yang baik dengan rerata z scoretinggi badan menurut umur, berat badan menurut umur dan berat badan menurut tinggi badan lebih besardari -2SD.Simpulan : Terdapat peningkatan kandungan energi, protein, z score berat badan menurut tinggi badansebelum dan setelah penyuluhan, namun tidak bermakna. Sedangkan z score tinggi badan menurut umurada peningkatan bermakna (p=0,03)Kata kunci : Status gizi, Makanan Pendamping ASI, keluarga nelayan