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Journal : JURNAL GIZI INDONESIA

Kadar seng dan kadar malondialdehyde pada penderita multi drug resistant tuberculosis dan tuberkulosis sensitif Suparno, Suparno; Suhartono, Suhartono; Sofro, Muchlis Achsan Udji; Sulchan, Mohammad; Tjahjono, Kusmiyati
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.743 KB) | DOI: 10.14710/jgi.7.1.8-14

Abstract

Background: Zinc is the main constituent element of Superoxide Dismutase (SOD) which acts to protect cells from inflammation and the toxic effects of Reactive Oxygen Species (ROS). High ROS production induces fat peroxidation, and forms malondialdehyde (MDA) which causes oxidative stress.Objectives: This study aimed to analyze the difference of zinc and malondialdehyde levels among Multi Drug Resistant Tuberculosis and sensitive Tuberculosis.Methods: Crossectional study with 55 subjects consisted of 32 MDR-TB subjects and 23 subjects TB sensitive. Selection of subjects using consecutive sampling. Zinc and MDA serum was obtained from venous blood. Zinc and MDA concentration were assessed by quantitative colometric and Thiobarbituric Acid Reactive Substances (TBARS) respectively. Data were analized statistic by independent t-test and Mann Whitney test.Results: Zinc level of MDR-TB and TB sensitive were 74.85 (64 - 97) μg/dl and 73.03 (63 - 97) μg/dl respectively, while MDA of MDR-TB and sensitive TB were 2.262±1.055 nmol/mL and 2.66±0.992 nmol/mL. There was no significantly different in zinc level between MDR-TB and sensitive TB (p=1.000). Furthermore, there was not significantly different of MDA level between MDR-TB and sensitive Tuberculosis (p=0,147).Conclusion: There are no differences in zinc and MDA levels in patient between MDR-TB and sensitive TB.
Co-Authors Abdul Asib Abu Talkah Achmad Dwityanto, Achmad Adi, Nugroho Prasetya Afidah Silmi, Afidah Afriani, Devi Agung Kumoro Wahyuwibowo, Agung Kumoro Agus Heru Purnomo, Agus Heru Agus Wijayanto, Agus Agustihana, Seftyan Ahmad Nawawi Ahmadi Ahmadi Ajeng Cita Anggraini, Ajeng Cita Alpin Y, Rattiwizal Amalia, Mufidah Nur Amalia, Mufidah Nur Amin Setyo Leksono Amin Sumadyo, Amin Ana Hardiana, Ana Ananda, Mella Rizka Anang Santoso, Anang Anda Anda Anda Sanusi Andarwulan, Trisna Anggraeni, Astri Widyaruli Angreini Oktarina, Angreini Apriyus, Devri Ramdhan Aprizon Putra, Aprizon Ardiyati, Tiara Kusuma Ari Saptono, Ari Ariani Nurfakhirah, Ariani Arifiyanti, Fitria Ariswan Ariswan, Ariswan Ary Fawzi, Ary Ayu Fitri Utami, Ayu Fitri Bagiyono Bagiyono Bambang Ruwanto, Bambang Bandono, Adi Bandono, Adi Baveja, Pratibha Baveja, Pratibha Binoto, Destrianika Budi Prasetya Bulan G. Munthe Cholifah, Anjar Nur Daniel Yanuar Aditya Beny Prabowo, Daniel Yanuar Aditya Beny Dantje Salean, Dantje Dasilva, Beatrix Elvi Dawud Dawud, Dawud DEDDY MUCHTADI DEDI SOEDHARMA Desy Aryanti, Desy Dewi M. Prawiradilaga, Dewi M. Dewi Malia Prawiradilaga, Dewi Malia Dewi Rochsantiningsih Dewi, Rr Ponco Dhita Fardaniwuri, Dhita Diksono, Diksono Djemari Mardapi Dwijonagoro, Suwarna Dwiono, Rija Dyah Susilowati Pradnya Paramita, Dyah Susilowati Pradnya Eaton, James A. Eaton, James A. edi edi Edi Istiyono Edi Pramono Singgih, Edi Pramono Edi Purwanta Edidas Edidas, Edidas Eka Setiawati Eko Budi Prasetyo, Eko Endah Kumala Dewi Endang Fauziati Endang Werdiningsih, Endang Endra Susila Eni Kamal Erfiani, Nunun Nuki Erlin Eveline Eveline, Erlin Faidah, Ririn Tutik Fazini, Harum Nazra Ferli, Emantu Fitriya, Rahmatul Frank E Rheindt Fransiska Fransiska Fransiska R. Zakaria Ghozali, Raymond Allen Gwee, Chyi Yin Gwee, Chyi Yin Hadi Setiawan Hamim, Moh. Ismail Hanif, Imam Hanson, S.W. Hari Eko Irianto Hari Yuliarso, Hari Haryanto Haryanto Hasan Maksum Hendarto, Iqbal Dwi Hendro Tjahjono Heru Kuswanto Hidayat Ashari, Hidayat Husna, Abidah I Made Suparta Ikhwanudin, Khoirul Ilma, Risca Zaqia Imam Faisal Hamzah Indratama, Fatma Isnadi, Isnadi Jauhariatun Marfu’ah, Jauhariatun Jiwa, I Made Joko Nurkamto Jovita Tri Murtini Jumadi Jumadi Junil Adri, Junil Adri Juri, Juri Karmanis, Karmanis Kartika Fitri Annisa, Kartika Fitri Kartiko, Donni Khaireni Puspaningtyas, Khaireni Khoirunnisa Khoirunnisa Kirono, Rejo Kusmiyati Tjahjono Lantip Diat Prasojo Laxmita, Natasia Anggi Leny Pramesti, Leny M. Giatman M.J.A, Syayid Qosim Makmur Rangkuti Marta, Satria Ami Maulana, Rizkia Rahmani Maya Andria Nirawati, Maya Andria Meilina Estiani, Meilina Meiratnasari, Ayu Mila Faila Shofa Mohammad Sulchan Monitja, H.E. Muchlis Achsan Udji Sofro Mudilarto, Mudilarto Muhammad Ansori Muhammad Zaini Muhtia, Anggri Muhtia, Anggri Muhtia, Anggri Muljanah, Ijah Munzir, Abdullah Murdohardono, Dodid Murdohardono, Dodid N. Praptiningrum Nailul Izzah Nanda, Riska NEVIATY PUTRI ZAMANI Ng, Nathaniel Sheng Rong Ng, Nathaniel Sheng Rong Ngadiso Ngadiso Niken Arimbi, Niken Njib, Rifki Njib, Rifki Novi Eka Susilowati, Novi Eka Novitri, Awinda Nur Hamidah, Nur Nurdiansyah, Dian Hakip Nurhanifah Nurhanifah Nurul Hamidah, Nurul Nurul Huda Olivantina, Opsasi Olivantina, Rara Agista Oman Abdurahman Oyong Satriakusuma, Oyong Palupi, Saraswati Kendis Intan PERDANA, RIKI Pertiwi, Nonie Intan Peter R Wilton, Peter R Philippe Verbelen, Philippe Prasetiawan, Heru Pratomo, Setyohadi Pribadi, Pribadi Purwandari, Ernisa Putiri B. Katili, Putiri B. Putra, I Nengah Putri Abadi, Nuri Yuniar Wahyu R. Yossi Aprian Sari Rachmadi Nugroho, Rachmadi Rachmaniar Rachmat Rahim, Bulkia Rahmatika, Annisa Ramadhani, Raden Roro Indira Rany, Tiara Delvika Ratna Dwi Astuti, Ratna Dwi Relita, Dessy Triana Remon Lapisa Revantoro, Nemesius Bambang Rheindt, Frank E. Rheindt, Frank E. Rheindt, Frank Erwin Rheindt, Frank Erwin Rinanda, Desika Riono, Riono Riono, Riono Ristika Ramadini, Ristika Riyan Pandu Wijayanto, Riyan Pandu Riza Auliwati, Riza Roikhan Roikhan, Roikhan Rosana Dewi Yunita Rosana Dewi, Rosana Rosenthal, A.J. rosidi, abdul majid Rosyidi, Moh. Ririn Rovikasari, Mala Rovikasari, Mala Roziqoh Roziqoh Ruben, Tinting Rufaidah, Anik Rulina Suradi, Rulina S Suharyo, Okol Sa'adah, Lailatus Sabtanto Joko Suprapto Samsudi Samsudi Saprianto, Saprianto Setyaningsih, Kuntum Palupi Sirenden, R. T. Siti Nurjanah Slamet Supriyadi Soemarno Soemarno Sofiyanurriyanti, Sofiyanurriyanti Sri Lestari Suarilah, Ira Subekti, Agung Tri Subekti, Agung Tri Sudjiwanati, Sudjiwanati Suendari, Reni Sugito Sugito Suharjo, Bambang Suharjo, Bambang Suhartono Suhartono Sukandari, Benny SUMADI SUMADI Sumardi Sumardi Sunardi Sunardi Sunaryo Sunaryo Sunaryo, Alexius Sungkono Sungkono Suparno, Agus Supri, Slamet Supri, Slamet Supriadi Supriadi Surya, Juanda Suryaningrum, Theresia Dwi Susanto, Arica Dwi Susi Endang Era Wati Sutrasno Sutrasno Syah, Fadiel Muhammad Syarifatul Fitria, Syarifatul Tanjung, Salsabila Hasiana Tarjana, Sri Samiati Tawaqal, Irzal Tjiptohadi Sawarjuwono Tri Mardiyanti, Tri Tri Ratnawati Tri Utami Tri Yuni Iswati Tuty Sariwulan, Tuty Ummul Mustaqimah, Ummul Usmeldi Usmeldi Vegisari, Vegisari Wena, Made Widodo Soemadi Winara, Pino Yudhi Winerungan, S. A. J. Wulan Cahyaning Maharani, Wulan Cahyaning Yudhi Satria Restu Yulis Setiya Dewi, Yulis Setiya Yuni Dhamayanti, Yuni Yusman Wiyatmo, Yusman Yusuf Palgunanto, Yusuf Yusup, Mabrur Muhammad Zatar, Anjelika