Taralan Tambunan
Faculty of Medicine University of Indonesia Dr. Cipto Mangunkusumo Hospital, Jakarta

Published : 51 Documents
Articles

BRAINSTEM AUDITORY EVOKED POTENTIALS FEATURES IN THALASSEMIA MAJOR Passat, Jimmy; Munthe, Bulan Ginting; Mahfuzh, Fauzi; Tambunan, Taralan
Paediatrica Indonesiana Vol 41 No 5-6 (2001): May 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.3.2001.166-70

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Patients with thalassemia major are at high risk for hearing impairment. The objective of the study is to determine the prevalence, grade and type of hearing impairment according to brainstem auditory evoked potentials (BAEP) investigation in thalassemia major. A descriptive cross sectional study was conducted between December 1999 until August 2000 in 72 thalassemic patients between 3 and 18 years of age. Only 65 patients were evaluated, because of time limitation. The results showed the prevalence of hearing impairment in thalassemia major was 29.2%. Most of them were moderate to severe unilateral sensorineural hearing impairments. Mild sensorienural hearing impairment occured in only 12.3%. Conductive  hearing impairment was only found in 1 patient. Hearing impairment was frequently found between 7 to 12 years of age (41.5%). Conclusion: the prevalence of hearing impairment in thalassem a major according to BAEP investigation is high and BAEP examination should be done regularly in all of thalassemic patients to investigate early detection and treatment of hearing impairment. 
URINARY INCONTINENCE IN CHILDREN IN CIPTO MANGUNKUSUMO HOSPITAL, JAKARTA: A SERIAL CASE REPORT Tambunan, Taralan
Paediatrica Indonesiana Vol 41 No 5-6 (2001): May 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.3.2001.171-4

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Urinary incontinence in children is a complex problem of varying causes. Most children brought to physician for evaluation of difficulties with urinary control will have single or diurnal enuresis, or will be experiencing urgency associated with functional or organic incontinence. To find out the magnitude of urinary incontinence problems in Child Health Department Cipto Mangunkusumo Hospital Jakarta, we retrospectively looked at medical report of such cases between the years of 1989-2001. During eleven years there were 20 cases, consisted of 10 males and 10 females, aged ranged between 3 months up to 16 years. Nineteen children showed significant bacteriuria defined as a urinary tract infection. Ten children were diagnosed as having neurogenic bladder, all had spinal lesions; 7 children had spinal dysraphyism while 3 others had osteolityc lesions in vertebrae due to malignancy. Non neurogenic bladder was defined in 6 children, while in other 4 children we defined that urinary incontinence was caused by anatomical abnormalities. Vesico-ureteral reflux in various degree were found in 9 children, while 11 out of 20 (55%) cases were experiencing chronic renal failure on their first visit. Although the annual incidence of urinary incontinence is low, these difficult cases causing many problems. Breakthrough infection was almost unpreventable and in most cases had progressed to renal failure. Many factors such as invasive procedures and prolonged treatment causing fear and frustration to the patients and their parents leading to poor compliance and lost to follow up. In summary we can conclude that urinary incontinence in children is a complex problem include medically, economically, and socially, not only for the patient and their parents, but also for medical profession.
COMPARISONS OF BONE MINERAL DENSITY IN STEROID DEPENDENT, FREQUENT RELAPSE, AND INFREQUENT RELAPSE NEPHROTIC SYNDROME CHILDREN Nurmala, Lies Dewi; Tambunan, Taralan; Amir, Idham
Paediatrica Indonesiana Vol 50 No 4 (2010): July 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.4.2010.193-8

Abstract

Background Children with nephrotic syndrome, especially those with steroid dependent and frequent relapse are at greater risk of reduced bone mineral density (BMD).Objective To determine bone mineral density (BMD) in steroid dependent and frequent relapse compared to infrequent relapse nephrotic syndrome.Methods We conducted a cross-sectional study at the Child Health Department, Cipto Mangunkusumo Hospital, from August until November 2009. Subjects were 5 to 18 year-old children with steroid dependent nephrotic syndrome (SDNS), frequent relapsenephrotic syndrome (FRNS), or infrequent relapse nephrotic syndrome (IRNS). Ionized calcium level, vitamin 25(OH)D3 level, and BMD were measured us ng dual energy x-ray absorptiometry (DEXA).Results 11 SDNS and 11 FRNS cbildren (group I) were compared with 22 IRNS children (Group II). Children of SDNS and FRNS had significantly longer duration of illness, more relapses, longer steroid therapy duration, and greater cumulative steroid dose compared to group 11 (IRNS). There were no differences between  the two groups with regard to mean ionized calcium level and vitamin 25(OH)D3 level. Children in group I had lower z-scores compared to group lI, but the difference was not statistically significant r mean (SD) -1.182 (1.21) vs. -0.795 (1.25), P=0.305]. Subgroup analysis showed that SDNS children had lower z-scores than FRNS [-1.791 (1.17) vs. -0.57 (0.94), P=0.019] and IRNS [-1.791 (1.17) vs. -0.795 (1.25), P=O.026].Conclusion Children with SDNS have significantly lower BMD z-scores compared to those with FRNS and IRNS.
Clinical and laboratory manifestations of childhood and adult-onset systemic lupus erythematosus in Cipto Mangunkusumo Hospital Faisal, Syarif; Akib, Arwin; Tambunan, Taralan
Paediatrica Indonesiana Vol 43 No 6 (2003): November 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.727 KB) | DOI: 10.14238/pi43.6.2003.199-204

Abstract

Background Childhood-onset SLE is more severe than the adult type.Objective To compare the clinical and laboratory manifestationsof childhood- and adult-onset systemic lupus erythematosus (SLE).Methods A retrospective study on child and adult SLE patientswas conducted in the Division of Pediatric Allergy and Immunol-ogy, Department of Child Health and Department of Internal Medi-cine, Medical School, University of Indonesia/CiptoMangunkusumoHospital (FKUI/RSCM) Jakarta.Subjects One hundred and twenty-nine subjects met the studycriteria consisting on 54 childhood- onset (41.9%), 75 adult-onset(58.1%), and 122 (94.6%) females and 7 (5.4%) males from Janu-ary 1995 until December 2000.Results Fever, arthralgia and vasculitis were the most frequentsigns found in both childhood-onset and adult-onset SLE. The liver,spleen, lymph nodes, cardiovascular, gastrointestinal tract, andeyes were the organs involved and significantly had a larger pro-portion in the childhood-onset. Decrease of C3 was more frequentlyfound in the childhood-onset. Out of 17 childhood-onset patientswho died, 13 died at the age of 0-11 year-old. Two of the adult-onset patients also died.Conclusion Childhood-onset SLE had some different character-istics compared to adult form
Covert bacteriuria in schoolchildren Tambunan, Taralan; Kumalawati, Yuli; Trihono, Partini P.; Giantiti, Astuti; Kadim, Muzal; Irawani, Vera
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.965 KB) | DOI: 10.14238/pi41.1.2001.38-41

Abstract

Covert bacteriuria is defined as significant bacteriuria detected during a screening program, This study was done as a pari of pilot program held by Medical School University of Indonesia namely Community Health Program. The screening was carried out at four Primary School al Cibubur Subdistrict Eastern Jakarta. The population target was focused on children at the third, four1h and fifth grade from each school. Screening urinalyses include examinatiOfl for the presence of glucose, protein, blood and bacteria. There were 460 children enrolled to this study, but only 449 cases were eligible for assessment comprising 217 males and 232 females aged ranged between 7.4-14.1 years. Covert bacteriuria were found in ten cases (2.22%), comprising five males and females consecutively. Antibiotics were not given. Repeated urine culture done two weeks later revealed that six cases cured spontaneously, four other cases still showing bacteriuria although all cases remain asymptomatic. We conclude that covert bacteriuria in schoolchildren is a benign condition, most of them are spontaneously cured without antibiotic treatment. This conclusion is in accordance with the opinion of most authors that screening for bacteriuria in healthy children does not have a place in any age group including schoolchildren.
Nephrologic abnormalities in neonatal asphyxia at Cipto Mangunkusumo Hospital, Jakarta Amir, Idham; Manoe, Vera M; Tambunan, Taralan
Paediatrica Indonesiana Vol 44 No 2 (2004): March 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.145 KB) | DOI: 10.14238/pi44.2.2004.66-72

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Introduction Neonatal asphyxia is still the leading cause of highmorbidity and mortality in developed countries, as well as in devel-oping countries including Indonesia. As a response to asphyxia,renal hypoxia occurs which is initially temporary, but if persisting,can cause permanent damage to the cortex and medulla.Objective The purpose of this study was to determine thenephrologic abnormalities in neonatal asphyxia at CiptoMangunkusumo Hospital.Methods This was a cross sectional descriptive study conductedin the Division of Neonatology, Cipto Mangunkusumo Hospital fromAugust until November 2002. Neonates with congenital malforma-tion were excluded.Results The study showed that the incidence of nephrologic ab-normalities in neonatal asphyxia based on Apgar scores at 1, 5,and 10 minutes were 65/100, 26/33, and 5/6, respectively. The riskof nephrologic abnormalities was not statistically different in se-vere asphyxia compared to moderate asphyxia. Severe asphyxiaat 1 minute Apgar scores was correlated with the occurrence ofoliguria.Conclusion In asphyxiated newborn, it is very important to inves-tigate the possibility of nephrologic abnormalities
Probiotic treatment in children with lactose intolerance – An open labeled the one group pre-test post-test experimental study Arifin, Zainul; Boediarso, Aswitha D.; Tambunan, Taralan
Paediatrica Indonesiana Vol 46 No 3 (2006): May 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.3.2006.139-43

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Background Lactose intolerance is the most common disorder ofintestinal carbohydrate digestion. Probiotic that contains the cor-rect strain in appropriate amount can be used as an alternativedietary for lactose intolerance patients.Objective This study was designed to describe the role of probioticin relieving lactose intolerance symptoms in children consumedfull-cream milk.Methods This study was a clinical trial. Inclusion criteria was chil-dren aged 12-14 years old, had a good nutrition and health status,with positive breath hydrogen test (BHT) result and lactose intoler-ance symptom(s), and their parents gave consent. Forty-two chil-dren were included. All subjects consumed one glass (200 ml) offull-cream milk twice a day for 21 days and recorded intolerancesymptoms. Probiotic was added from 8 th to 21 st day in their milk,and responses of treatment were evaluated by scoring system(based on borborigmic, flatulence, abdominal bloating, nausea andvomiting, abdominal pain, and diarrhea symptoms). At the end ofstudy they were undergone second BHT examination.Results There were decreasing mean score rates at 7 th day (pre)13.8 (SD 5.5) compared with 7.5 (SD 3.5) at 14 th day (after) andwas statistically significant (P<0.001). Mean score rate at 7 th day(pre) 13.8 (SD 5.5) compared with 21 st day (after) was 0.119 (SD0.55) and was statistically significant (P<0.001). At the end of study,only 2 subjects showed clinical signs of lactose intolerance. Thirty-six subjects had normal BHT result at 21 st day and was statisti-cally significant (P<0.001).Conclusion Two weeks administration of probiotic could relievelactose intolerance symptoms in children consumed full-cream milk
COLLOID ONCOTIC PRESSURE IN CHILDREN WITH NEPHROTIC SYNDROME Tambunan, Taralan; Alatas, H.; Wirya, I. G. N. Wila; Harmanses, S.; Chair, I.; Simanjuntak, R.
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi28.9-10.1988.200-8

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To evaluate the correlation between plasma protein concentration and colloid oncotic pressure (COP) and their influence on clinical symptom of edema, we studied 30 children with nephrotic syndrome (NS). Total plasma protein concentration (TP), albumm, globulin and COP were measured in all patients in edema forming state (EF) and m steady state phase (SS), except for COP, only 16 samples in SS phase. COP TP plasma albumin and globulin contents in EF group were 8. 7 ± 2. 7 mmHg, 4.07 '± 0.68 g/dl; 2.57 ± 0.50 g/dl and 1.51 ± 0.32 g/dl, respectively. In SS group these figures rose significantly to 16.7 ± 3.9 mmHg for COP; 5. 70 ± 0.99 g/dl for TP; 3.46 ± 0.52 g!dl and 2.06 ± 0.56 g/dl for plasma albumin and globulin, respectively. We also found the high correlation both between COP and albumin content (r= +0.58; p < 0.01) and between COP and TP (r= +0.54; P < 0.01) . A strong negative correlation was also found between COP and the degree of edema (r = _ 0.55; p <0.01). On the other hand a very low grade correlation was noticed between plasma albumin content and  the degree of edema (r= - 0.26; P < 0.05) and no correlation at all was found between edema and TP (r= - 0.19; P > 0.05). We conclude that COP has the highest correlation with plasma protein concentration and the degree of edema, and can be used as a diagnostic tool. It is even more sensitive and simple compared with the TP or albumin content determination.
STUDIES OF BLOOD PRESSURE AND PREVALENCE OF HYPERTENSION IN SCHOOLCHILDREN IN JAKARTA Wirya, I. G. N. Wila; Alatan, Husein; Tambunan, Taralan; Harmanses, S.; Windiastuti, Endang
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi28.9-10.1988.183-91

Abstract

Blood pressure measurement was done on 4983 school children of 6 - 18 years schoolchildren was at random so that the sample population represented the children in Jakarta. The incidence of hypertension in this study is about 3.11 %, of which most are found at the age of 15 years.
Evaluasi Penggunaan Antibiotik dengan Kartu Monitoring Antibiotik Gyssens Yuniar, Irene; Karyanti, Mulya Rahma; Tambunan, Taralan; Rizkyani, Nanda Asyura
Sari Pediatri Vol 14, No 6 (2013)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp14.6.2013.384-90

Abstract

Latar belakang.Masalah infeksi yang sering ditemui di ICU anak, disebabkan berbagai pemakaian antibiotik. Peningkatan penggunaan antibiotik diikuti dengan risiko penurunan kepekaannya sehingga perlu pengendalian pemakaiannya.Tujuan.Evaluasi penggunaan antibiotik secara kualitatif di Pediatric Intensive Care Unit(PICU) dengan menggunakan alur Gyssens.Metode.Uji potong lintang retrospektif dengan mengevaluasi penggunaan antibiotik melalui kartu monitoring serta dilakukan analisis dengan alur Gyssens di PICU dari tanggal 10 Februari 2012 sampai 31 Juli 2012.Hasil.Selama kurun waktu 5 bulan, 233 pasien dirawat di ICU Anak RS. Cipto Mangunkusumo Jakarta dan 45 (19,3%) pasien menggunakan antibiotik. Penggunaan antibiotik terbanyak pada kelompok umur 1 bulan sampai 1 tahun. Pada 83 penggunaan antibiotik, 64 antibiotik dipakai sebagai terapi empiris, 11 definitif, dan 8 profilaksis. Lima antibiotik terbanyak yang digunakan adalah sefotaksim, amikasin, piperasilin tazobaktam, meropenem, dan metronidazol. Penggunaan antibiotik yang tepat (alur Gyssens kategori I) didapatkan pada 53% pasien yang dirawat di PICU.Kesimpulan. Penggunaan antibiotik dengan justifikasi yang tepat dapat diterapkan dan diharapkan dapat menurunkan resistensi antibiotik, mengurangi beban biaya pasien serta meningkatkan kualitas pelayanan pasien di ICU Anak. Selain itu, diperlukan pelatihan pengambilan spesimen yang tepat secara berkala, serta dihimbau untuk mengisi formulir antibiotik secara tepat dan benar.
Co-Authors ABdoerrahman, M. Hardjono Abidin S., Abidin Agus Firmansyah Alan Roland Tumbelaka, Alan Roland Alatan, Husein Alatan, Husein Alatas H., Alatas Alifiani H. Putranti, Alifiani H. Aman B. Pulungan Aminullan, Asril Antonius H. Pudjiadi, Antonius H. Arbi, Fahrul W. Ariz Pribadi, Ariz Arwin Akib, Arwin Arwin AP Akib, Arwin AP Aswitha D. Boediarso, Aswitha D. Attila Dewanti, Attila Ayi Dilla Septarini, Ayi Dilla Badriul Hegar Bambang Madiyono Bambang Tridjaja, Bambang Budi, Lenny S. Bulan Ginting Munthe, Bulan Ginting Cahyani Gita Ambarsari, Cahyani Gita Chair, I. Citra Raditha, Citra Cornain, S. Daisy Widiastuti, Daisy Damayanti Rusli Sjarif Debbie Latupeirissa, Debbie Diana Aulia Edi S Tehuteru, Edi S Eka Laksmi Hidayati, Eka Laksmi Endang Windiastuti Erwin Lukas Hendrata, Erwin Lukas Eva Miranda Marwali, Eva Miranda Faisal, Syarif Felliyani, Felliyani Giantiti, Astuti Gunardjono Gunardjono H. Alatas Harmanses, S. Harun, Sri Rezeki Henny Adriani Puspitasari, Henny Adriani Himawan, S. Hindra I. Satari, Hindra I. Husein Alatas I. G. N Wila Wirya, I. G. N Wila I. G. N. Wila Wirya, I. G. N. Wila Idham Amir Imral Chair, Imral Irawan Mangunatmadja, Irawan Irawani, Vera Irene Yuniar, Irene Iswari Setianingsih Jose R. L. Batubara, Jose R. L. Lineus Hewis, Lineus M. Tatang Puspanjono, M. Tatang Mahfuzh, Fauzi Mardjanis Said, Mardjanis Marissa Tania Stephanie Pudjiadi, Marissa Tania Stephanie Miesien Miesien, Miesien Mulya Rahma Karyanti, Mulya Rahma Munar Lubis, Munar Muzal Kadim N, Eveline P Najib Advani Nanda Asyura Rizkyani, Nanda Asyura Nurmala, Lies Dewi Oswari, Atiek Widya Palilingan, Pingkan Partini P Trihono, Partini P Partini P. Trihono, Partini P. Partini P. Trihono,, Partini P. Passat, Jimmy Purwanto, S. Harry Pustika Amalia Rahayoe, Nastiti N Rahmat, Dedy Rina A.C. Saragih, Rina A.C. Rosalina Roeslani, Rosalina Rulina Suradi, Rulina Saptawati Bardosono Setyo Handryastuti, Setyo Simanjuntak, R. Situmeang, Esther H. Sri Lilijanti Widjaja, Sri Lilijanti Sri Rezeki S Hadinegoro, Sri Rezeki S Sri S Nasar, Sri S Sucahyo Sucahyo, Sucahyo Sudigdo Sastroasmoro Sudung O Pardede, Sudung O Sudung O. Pardede, Sudung O. Syafruddin Haris, Syafruddin Syamsu, Rianita Tania Nilamsari, Tania Utami, Meita Dwi Vera M Manoe, Vera M Widodo, Dwi P. Wirya, I.G.N. Wita Wirya, IGN Wila Yuli Kumalawati Yulia Iriani, Yulia Yuliatmoko Suryatin, Yuliatmoko Zainul Arifin Zakiudin Munasir