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Journal : Indonesian Journal of Chemistry

STRUCTURE ELUCIDATION OF BIOACTIVE ALKALOID COMPOUNDS ISOLATED FROM SPONGE Petrosia sp COLLECTED FROM BUNAKEN BAY MENADO Alam, Gemini; Astuti, Puji; Wahyuono, Subagus; Sari, Dinar; Hamman, Mark T
Indonesian Journal of Chemistry Vol 5, No 2 (2005)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1932.788 KB) | DOI: 10.22146/ijc.21828

Abstract

Two alkaloid compounds have been isolated from sponge Petrosia sp collected from Bunaken Bay Menado. These compounds have been found to inhibit several human cancer cell proliferation in vitro. Structure elucidation is needed to further characterize these bioactive compounds. The structure is determined by analyzing Ultra Violet (UV), Infra Red (IR), Mass Spectra (MS) and Nuclear Magnetic Resonance (NMR) spectra. Based on spectroscopic data, Thin Layer Chromatography (TLC) co-chromatograph with authentic samples and comparison with reported data the two compounds were identified as Manzamine A and 8-OH Manzamine A, respectively. Keywords: Manzamine A, 8-OH Manzamine A, Petrosia sp, stucture elucidation
Co-Authors Abdul Karim Zulkarnain Abdul Rohman Aditya Krishar Karim Ag. Yuswanto Agung Endro Nugroho Agustinus Yuswanto, Agustinus Ahmad Hamim Sadewa Ambarwati Ambarwati Ari Sartinah, Ari Ariani Hatmanti Arnida ., Arnida AWM. Boersma, AWM. B.S. Ari Sudarmanto, B.S. Ari Bambang Hariono Citra Prasetyawati, Citra Dinar Sari Djoko Santosa Djoko Santoso Ekowati Chasanah Endang Dwi Wulansari Endang Lukitaningsih Erna Prawita Setyowati Farisya Nurhaeni Fauziati, Vera Galih G, Galih Galih, G. Gemini Alam Hadi, Etik Erna Wati Hari Susanti HERNAYANTI HERNAYANTI Hosea Jaya Edy Ibnu G Gandjar, Ibnu G Ibnu G. Gandjar, Ibnu G. Ibnu G. Ganjar, Ibnu G. Ika Puspita Sari Imono A. Donatus, Imono A. Imono Argo D, Imono Imono Argo Donatus, Imono Argo Indah Purwantini Isnindar Isnindar, Isnindar JAKA WIDADA K. Nooter, K. Kaneko, Takushi Kazutaka maeyama Kumiko Terada KV Rao, KV L. Hartanto Nugroho LANGKAH SEMBIRING Linus Yhani Chrystomo Lukman Hakim Mae S.H. Wahyuningnsih, Mae S.H. Mae S.H. Wahyuningsih Mae Sri Hartati W, Mae Sri Mae Sri Hartati Wahyuningsih, Mae Sri Hartati Mae Sri Hartati, Mae Sri Mahardika, Arfian Bela Marchaban ., Marchaban Marchaban Marchaban, Marchaban Marchaban, . Marchaban, . Mark T Hamann, Mark T Mark T Hamman Mark T. Hamann, Mark T. Mimiek Murrukmihadi Moch. Saiful Bachri Mohd., Datin Maryati mufrod mufrod Muhammad Nursid Murwantoko Murwantoko Mustofa . Nanang Fakhrudin, Nanang Nunung Yuniarti Nur Hidayati Nuringtyas, Tri R. Nurlaila Nurlaila Peni Susilowati Putri, Peni Susilowati Perdana Priya Haresmita, Perdana Priya Pratiwi, Sylvia Puji Astuti Purwantiningsih, Purwantiningsih PUSPITA LISDIYANTI R.L.M. Bolhuis, R.L.M. Rarastoeti Pratiwi Ratna Asmah Susidarti Retno Wahyuningrum Rijai, Hifdzur Rashif Ritmaleni Ritmaleni RR. Endang Lukitaningsih S.M. Widyastuti Sakti, Dika Sotya Samsul Hadi Sebastian Margino Sita Rina Widyarini, Sita Rina Sitarina Widyarini Soesanto Tjokrosonto Sofia Mubarika Sorta Basar Ida Simanjuntak Sri Sudewi, Sri Sri Wahdaningsih, Sri Sudarsono . Sudibyo Martono Sugeng Riyanto Sukarti Moeljopawiro Sutomo Sutomo suwaldi suwaldi Syamsudin . Tamhid, Hady Anshory Tanti Azizah S Tanti Azizah Sujono Tatang Irianti Tatsuo Takeya, Tatsuo Titik Nuryastuti, Titik Tri Lestari Tri R Nuringtyas, Tri R Triana Hertiani Tsutomu Nohno Vairappan, Charles S. Wahyono Wahyono Wahyuningsih, Mae Sri Hartanti Wayan Tunas Artama Widyastuti, S M Widyastuti, SM Widyastuti, SM Widyastuti, SM Yoga Pratama, Yoga Yuli Widiyastuti Yustina Sri Hartini, Yustina Sri Yuswanto Yuswanto Yuwantiningsih, Sri