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Effects of latihan pasrah diri in quality of life in chronic kidney disease-dialysis patients with depression symptoms Widyaningrum, Widyaningrum; Siswanto, Agus; Djarwoto, Bambang
Acta Interna The Journal of Internal Medicine Vol 3, No 2 (2013): Acta Interna The Journal of Internal Medicine
Publisher : Acta Interna The Journal of Internal Medicine

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Abstract

ABSTRACTBackground: Patients with chronic kidney disease (CKD) suffering from various physical and emotional symptoms show depression and disturbance in quality of life. Patients with chronic kidney disease have a decreased quality of life, and mortality rate about 22% in every year. Depression in patients with CKD must be managed properly because a large effect on HRQOL (Health Related Quality of Life) and the potential side effects on the management of patients with CKD. Latihan pasrah diri (LPD) is a method combining relaxation and remembrance with a focus on breathing exercises and words contained in the dhikr (relaxation and repetitive prayer). The rise of the relaxation response is expected to improve the symptoms of stress or depressive symptoms, which is expected to improve HRQOL.Objective: This study aimed to determine the effect of LPD on quality of life in hemodialysis patients with depressive symptoms that was compared with controls.Methods: The research constituted the study of Randomized Control Trial. The research was measured the KDQOL-SF scores (Kidney Disease Quality of Life-SF) in subjects with LPD treatment during 21 days, compared with controls. The research was conducted at the Hemodialysis Unit of Dr. Sardjito Hospital, Yogyakarta, from May to June 2012. A total of 36 patients who met the inclusion criteria were randomized and divided into LPD group (n = 18) and control group (n = 18).Results: Found a statistically signifi cant decrease in BDI scores in both groups, 23.00 ± 5.34 to 15.00 ± 8.55 (p = 0.001) in the LPD group and 23.00 ± 5.34 to18.33 ± 6, 66 (p = 0.022) in the control group. KDQOL-SF scores after treatment when compared between the LPD and control groups experienced different changes were statistically signifi cant in domains effects of kidney disease 59.65 ±23.52 compared to 39.41 ± 20.03 (p = 0.022), sleep 69 ± 13.17 compared to 46.53. (p = 0.000), overall health 73.89 ± 16.85 compared to 57.22 ± 19.04 (p = 0.009), pain 64.86 ± 20.80 compared to 42.36 ± 24.90 (p = 0.005), general health 53.88 ±16.05 compared to 47.78 ± 20.74 (p = 0.014), and the physical component scale 35.98 ± 6, 83 compared to 29.12 ± 6.46 (p = 0.004). Despite increased KDQOL-SF domain scores, but there were 2 domains that Δ KDQOL-SF score changes were statistically signifi cantly different compared with the control group, which was the domain of sleep and overall health.Conclusion: Latihan pasrah diri twice a day during 21 days (3 weeks) can improved the quality of life of patients with symptoms depression in CKD patients undergoing hemodialysis in domains of sleep and overall health.Keywords: CKD, depression, latihan pasrah diri, KDQOL-SF.
Ekstraksi dan Karakterisasi Pektin dari Buah Pandan Laut (Pandanus tectorius) widyaningrum, Widyaningrum; Lutfi, Musthofa; Nugroho, Wahyunanto Agung
Jurnal Keteknikan Pertanian Tropis dan Biosistem Vol 2, No 2 (2014)
Publisher : Universitas Brawijaya

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Abstract

Pektin merupakan senyawa aditif yang berfungsi sebagai gelling agent. Sejauh ini kebutuhan terhadap pektin terpenuhi dari hasil impor, padahal sumber pektin sangat mudah didapat. Salah satu sumber pektin yang mungkin adalah pektin yang berasal dari buah? Pandanus tectorius dikarenakan masih sangat sedikit pemanfaatan dan penelitian tentang tanaman tersebut sehingga dirasa perlu untuk dilakukan penelitian ekstraksi pektin. Penelitian ini bertujuan untuk mengetahui pengaruh suhu dan waktu ekstraksi terhadap kualitas pektin yang dihasilkan dari buah Pandanus tectorius serta mencari kombinasi yang tepat untuk memperoleh hasil yang baik. Pengambilan pektin dari buah Pandanus tectorius dilakukan dengan metode ekstraksi dengan menggunakan pelarut air yang diasamkan dengan menambahkan asam klorida. Analisa yang dilakukan meliputi rendemen, kadar air, berat ekuivalen, kadar metoksil, kadar abu, kadar asam galakturonat dan kekuatan gel. Variasi suhu dan lama pemanasan berpengaruh terhadap banyaknya pektin yang dihasilkan dimana pektin tertinggi didapatkan pada ekstraksi suhu 80?C dan 80 menit yaitu sebesar 14.26%. Berdasarkan metode Bayes pektin terbaik yang dihasilkan adalah pektin hasil ekstraksi suhu 80?C selama 80 menit. Pektin dengan kondisi ekstraksi terbaik kemudian dibandingkan dengan pektin komersial. Parameter yang dibandingkan adalah parameter yang sesuai dengan standar yang ditetapkan Food Chemical Codex. Pektin hasil penelitian memiliki mutu yang lebih baik daripada pektin komersial. ? Kata kunci : ekstraksi, karakterisasi, Pandanus tectorius, Pandan laut, pektin.
IDENTIFIKASI KROMATOGRAFI LAPIS TIPIS DAN EFEKTIVITAS EKSTRAK ETILASETAT DAUN TALOK (MUNTINGIA CALABURA L) SEBAGAI ANALGETIK Widyaningrum, Widyaningrum; Saptuti, Sri; Agustina, Veronika Tria; Sulistiyah, Wella
Avicenna : Journal of Health Research Vol 2, No 1 (2019): Maret
Publisher : STIKES Mamba'ul 'Ulum Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.956 KB) | DOI: 10.36419/avicenna.v2i1.263

Abstract

Latar Belakang : Kersen atau talok merupakan salah satu tanaman yang dapat berkhasiat sebagai analgetik, antiinflamasi dan antipiretik. Senyawa kimia yang terkandung di dalamnya antara lain flavonoid, polifenol, tannin, triterpen dan saponin. Tujuan : Untuk melakukan identifikasi profil kromatografi lapis tipis ekstrak etilasetat daun talok (EEADT) dan melakukan pengujian efektivitasnya sebagai analgetik melalui induksi kimia yang diberikan pada mencit jantan ras Swiss. Metode : Penyarian daun talok dilakukan dengan pelarut etilasetat menggunakan metode maserasi. Maserat kemudian diuji fitokimia dilanjutkan pengujian kromatografi lapis tipis (KLT). Selanjutnya dilakukan pengujian efektivitas EEADT sebagai analgetik menggunakan metode induksi kimia. Sampel hewan uji adalah mencit jantan, yang dibagi 5 kelompok perlakuan, yaitu kontrol negatif minyak goreng, kontrol positif asetosal dosis 65 mg/kgBB, kelompok 1 yaitu EEADT dosis 60 mg/kgBB, kelompok II yaitu EEADT dosis 120 mg/kgBB dan kelompok III adalah dosis 240 mg/kgBB. Induksi kimia menggunakan asam asetat 1% secara intraperitoneal kemudian diamati geliat yang timbul pada mencit. Data yang diperoleh kemudian dihitung daya analgetiknya lalu dianalisis menggunakan SPSS melalui uji ANOVA. Hasil : Hasil maserasi berupa ekstrak kental etilasetat dengan rendemen sebesar 8,41%. Hasil pengujian skrining fitokimia menunjukkan bahwa ekstrak etilasetat positif pada uji pendahuluan, kemudian uji lanjutan positif terhadap alkaloid, antrakinon, tannin, saponin dan flavonoid. Pada identifikasi KLT menunjukkan adanya bercak alkaloid, antrakinon dan flavonoid. Hasil pengujian efektivitas analgetik pada EEADT adalah berturut-turut asetosal, dosis 60mg/kgBB; 120 mg/kgBB dan 240 mg/kgBB yaitu 37,74%; 6,40%; 16,42% dan 32,09%. Simpulan : EEADT mengandung senyawa alkaloid, antrakinon dan flavonoid. EEADT memiliki efektivitas sebagai analgetik.
Effects of latihan pasrah diri in quality of life in chronic kidney disease-dialysis patients with depression symptoms Widyaningrum, Widyaningrum; Siswanto, Agus; Djarwoto, Bambang
Acta Interna The Journal of Internal Medicine Vol 3, No 2 (2013): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3611.193 KB) | DOI: 10.22146/acta interna.5000

Abstract

ABSTRACTBackground: Patients with chronic kidney disease (CKD) suffering from various physical and emotional symptoms show depression and disturbance in quality of life. Patients with chronic kidney disease have a decreased quality of life, and mortality rate about 22% in every year. Depression in patients with CKD must be managed properly because a large effect on HRQOL (Health Related Quality of Life) and the potential side effects on the management of patients with CKD. Latihan pasrah diri (LPD) is a method combining relaxation and remembrance with a focus on breathing exercises and words contained in the dhikr (relaxation and repetitive prayer). The rise of the relaxation response is expected to improve the symptoms of stress or depressive symptoms, which is expected to improve HRQOL.Objective: This study aimed to determine the effect of LPD on quality of life in hemodialysis patients with depressive symptoms that was compared with controls.Methods: The research constituted the study of Randomized Control Trial. The research was measured the KDQOL-SF scores (Kidney Disease Quality of Life-SF) in subjects with LPD treatment during 21 days, compared with controls. The research was conducted at the Hemodialysis Unit of Dr. Sardjito Hospital, Yogyakarta, from May to June 2012. A total of 36 patients who met the inclusion criteria were randomized and divided into LPD group (n = 18) and control group (n = 18).Results: Found a statistically signifi cant decrease in BDI scores in both groups, 23.00 ± 5.34 to 15.00 ± 8.55 (p = 0.001) in the LPD group and 23.00 ± 5.34 to18.33 ± 6, 66 (p = 0.022) in the control group. KDQOL-SF scores after treatment when compared between the LPD and control groups experienced different changes were statistically signifi cant in domains effects of kidney disease 59.65 ±23.52 compared to 39.41 ± 20.03 (p = 0.022), sleep 69 ± 13.17 compared to 46.53. (p = 0.000), overall health 73.89 ± 16.85 compared to 57.22 ± 19.04 (p = 0.009), pain 64.86 ± 20.80 compared to 42.36 ± 24.90 (p = 0.005), general health 53.88 ±16.05 compared to 47.78 ± 20.74 (p = 0.014), and the physical component scale 35.98 ± 6, 83 compared to 29.12 ± 6.46 (p = 0.004). Despite increased KDQOL-SF domain scores, but there were 2 domains that Δ KDQOL-SF score changes were statistically signifi cantly different compared with the control group, which was the domain of sleep and overall health.Conclusion: Latihan pasrah diri twice a day during 21 days (3 weeks) can improved the quality of life of patients with symptoms depression in CKD patients undergoing hemodialysis in domains of sleep and overall health.Keywords: CKD, depression, latihan pasrah diri, KDQOL-SF.
Desain Sistem Kontrol dan Monitoring Kondisi Udara pada Controlled Atmosphere Storage Berbasis Mikrokontroler Arduino Uno Widyaningrum, Widyaningrum; Purwanto, Yohanes Aris; Mardjan, Sutrisno
Jurnal Keteknikan Pertanian Vol. 6 No. 1 (2018): JURNAL KETEKNIKAN PERTANIAN
Publisher : PERTETA

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Abstract

AbstractStorage by controlling the composition of air or oxygen and carbon dioxide concentration settings is called controlled atmosphere storage. Controlled atmosphere storage aims at controlling metabolism of fresh product to extended the shelf-life. The concentration of oxygen and carbon dioxide in product aremaintained at a desired concentration. The objective of this research was to design a control and monitoring system of oxygen, carbon dioxide, temperature and relative humidity in the storage by using Arduino Uno microcontroller. Design approach consists of functional and structural design. The main function of thesystem control were to control gas injection, open and close the solenoid valve, control the amount of injection, and reading the sensor. Measurements and testing included sensor calibration and functional testing of the control and monitoring system with no-load conditions. Analysis of the experiment resultswas conducted by using statistical analysis of repeated measures ANOVA. The result of observation and measurements of temperature with no-load conditions was 9.88ºC, RH 73.73%, concentration of carbon dioxide 2.22% and concentration of oxygen 4.63%. Accuracy between setpoint and actual temperature was of 98.84%. Accuracy between setpoint and actual RH was of 97.55%. Accuracy between setpoint and actual oxygen was of 83.98%. Accuracy between setpoint and actual carbon dioxide was of 74.26%.AbstrakPenyimpanan dengan cara pengaturan komposisi udara atau pengaturan konsentrasi oksigen dan karbondioksida dikenal dengan penyimpanan dengan pengendalian atmosfer. Teknik atmosfer terkendali sekitar produk bertujuan untuk mengendalikan metabolisme produk segar sehingga masa simpan dapat diperpanjang. Konsentrasi oksigen dan karbondioksida disekitar produk dijaga pada suatu konsentrasi yang diinginkan. Penelitian ini bertujuan untuk merancang sistem kontrol dan monitoring oksigen dan karbondioksida serta suhu dan kelembaban di dalam ruang penyimpanan dengan mengimplementasikan mikrokontroler Arduino Uno. Pendekatan rancangan terdiri dari dua jenis yaitu rancangan fungsional dan rancangan struktural. Fungsi dan struktur utama dari sistem yang dibuat adalah sistem pengontrolan terhadap injeksi gas, buka tutup solenoid valve, mengontrol lama injeksi, dan melakukan pembacaan sensor. Pengukuran dan pengujian meliputi kalibrasi sensor dan pengujian fungsional kinerja kontrol dan monitoring. Analisis hasil percobaan dilakukan dengan menggunakan analisis statistik repeated measures ANOVA. Hasil pengamatan dan pengukuran suhu adalah 9.88ºC, RH 73.73%, karbondioksida 2.22% dan oksigen 4.63%. Perbandingan antara setpoint dan aktual diperoleh akurasi suhu 98.84%. Perbandinganantara setpoint dan aktual diperoleh akurasi RH 97.55% Perbandingan antara setpoint dan aktual diperoleh akurasi oksigen 83.98%. Perbandingan antara setpoint dan aktual diperoleh akurasi karbondioksida74.26%.