Vienna Saraswaty, Vienna
Research Center for Chemistry-Indonesian Institute of Sciences (RCChem LIPI)

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A STUDY OF ESSENTIAL OIL FROM AN INVASIVE PIPER ADUNCUM L. Wibawa, I Putu Agus Hendra; Saraswaty, Vienna; Kuswantoro, Farid; Andila, Putri Sri; Wardhani, Putri Kesuma; Tirta, I Gede; Sujarwo, Wawan
Jurnal Biologi Udayana Vol 23 No 2 (2019): Jurnal Biologi Udayana
Publisher : Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Udayana

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Abstract

An invasive Piper aduncum is a plant species that potentially produces essential oil. The study aims todetermine the percentage, phytochemical compounds, and anti-fungal properties of essential oil producedfrom the leaves and fruits of Piper aduncum. The study showed that the leaves and fruits of P. aduncumcontain 0.30% and 0.33% of essential oil, respectively. Apiol is the most abundant phytochemical compoundobtained in essential oil of leaves and fruits of P. aduncum with 57.10% and 66.31%, respectively. Weconclude that essential oil obtained in this study is able to inhibit the growth of both Aspergillus niger andCladosporium sp. but not for Fusarium oxysporum and Fusarium solani.
EFFECT OF DEXTRIN AND LACTOSE IN PREPARATION OF POWDERS DOSAGE FORM FROM Centella asiatica EXTRACT Saraswaty, Vienna; Risdian, Chandra; Mozef, Tjandrawati; S. Kardono, Leonardus Broto
Teknologi Indonesia Vol 38, No 2 (2015)
Publisher : LIPI Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (16.054 KB) | DOI: 10.14203/jti.v38i2.153

Abstract

Objective of this research is to investigate the influence of dextrin and lactose in preparation of dosage form from Centella asiatica (CA) ethanol extract. Powders dosage form of CA ethanol extract was prepared by kneading method. Previously, it had been known that to create CA extract concentrate long time is needed, i.e. more than 7 days. Drying preparation of CA extract by thin layer film in oven blower at 50oC gave a shorter drying time, i.e. 6 hours but it gave sticky form at the end of process. Preparation process to produce powders dosage by using dextrin and lactose was succesfully investigated in our laboratory. It resulted that dextrin was appropriate filler for preparation of CA extract powder. Powder dosage form of CA extract could be obtained after 6 hours of drying and using 30% w/w of dextrin (based on the weigh of wet extract at density of 1,000 gr.mL-1). Difference on amount of dextrin in CA extract gave influence on water content, acidity (pH), compressibility index, haussner ratio, flow propert,y and angle of repose significantly.
ALPHA GLUCOSIDASE INHIBITORY ACTIVITY FROM Syzigium sp. Saraswaty, Vienna
Teknologi Indonesia Vol 33, No 1 (2010)
Publisher : LIPI Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (16.048 KB) | DOI: 10.14203/jti.v33i1.16

Abstract

Objective of this research is to investigate alpha glucosidase inhibitory activity from Syzygium species. 20 of syzygium species was extracted using 70% ethanol and evaporated to be tested for its alpha glucosidase inhibitory activity and resulted that S. cumini and S. syzygioides have a high alpha glucosidase inhibitory activity with IC50 value was 8.71 ppm and 7.48 ppm respectively. Further investigation on some parts of S. cumini plant showed that the highest activity was found in the cortex with IC50 value of 0.45 ppm. Fractionation of ethanolic extract of S. cumini cortex using n- hexane, dichloromethane, ethyl acetate, n-buthanol and water resulted that the highest yield was in water fraction with IC50 value of 8.15 ppm. Phytochemical screening assay showed that ethanolic extract of S. cumini cortex contained terpenoid, phenol, saponin, tannin and fl avonoid.