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THE EVALUATION OF TREATMENT PROFILE, COSTS AND CLINICAL OUTCOME USE OF HUMAN INSULIN AND ANALOGUE OF DM TYPE 2 BPJS PATIENT AT RSUD PASAR REBO IN PERIODE 0F 2016—2017 Sari, Dwi Puspita; Anggriani, Yusi; L, Dian Ratih
Preventif: Jurnal Kesehatan Masyarakat Vol 10, No 1 (2019): Juni
Publisher : Tadulako University

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ABSTRAK Diabetes Melitus (DM) merupakan sekelompok penyakit metabolik dengan karakteristik terjadinya peningkatan kadar gula darah (hiperglikemi), yang terjadi akibat kelainan sekresi insulin, aktivitas insulin dan keduanya. Penelitian ini bertujuan untuk mengetahui outcome klinis dan profil pengobatan pasien DM di RSUD Pasar Rebo serta mengetahu perbandingan biaya pengobatan DMT2 antara pasien yang menggunakan insulin manusia dan insulin analog. Analisis ini menggunakan variabel independen yaitu insulin manusia tunggal, insulin manusia + oral DM, insulin manusia + analog + oral DM, insulin analog tunggal, dan insulin analog + oral DM. Variabel dependennya adalah outcome klinis yaitu GDP, GDPP dan HBA1C. Sampel penelitian ini adalah pasien dengan diagnosa DMT2 rawat jalan dengan terapi insulin, baik insulin analog dan insulin manusia pada periode Januari 2016?Desember 2017 dengan jaminan BPJS dan minimum tiga kali kunjungan selama dua tahun di RSUD Pasar Rebo. Perhitungan minimum sampel berdasarkan rumus Krejcie-Morgan. Pengumpulan data dilakukan dengan menggunakan formulir yang menunjukan hasil terapi dengan nilai GDP, GDPP dan HBA1C, formulir yang menunjukan profil pengobatan DM, Non DM dan Insulin, dan formulin profil biaya. Metode statistik yang digunakan pada penelitian ini adalah uji statistik non-parametrik Kruskal Wallis. Hasil penelitian menunjukan profil pengobatan berdasarkan jenisnya penggunaan insulin analog pada tahun 2016 sampai 2017 sebesar (44,6%) bila dibandingkan dengan insulin manusia yang hanya (9,8%). Penggunaan insulin short acting pada tahun 2016 sebesar 39,5% sedangkan tahun 2017 lebih banyak sebesar 55,8%. Insulin dengan merk Lantus paling banyak digunakan pada tahun 2016 sebesar 42,36% dan Humulin R terbesar pada tahun 2017 sebanyak 36,68%. Secara outcome klinis penggunaan kelima jenis insulin memberikan perbedaan yang signifikan terhadap nilai HBA1C namun hanya pada jenis insulin manusia+ADO saja yang dapat memberikan perbedaan pada nilai GDPP. Rata-rata biaya insulin paling murah adalah jenis insulin manusia+ADO yaitu sebesar Rp 588.541,-Kata kunci : DMT2, Insulin Analog, Insulin Manusia,  BPJS, Pasien Rawat Jalan,  Outcome Klinis ABSTRACTDiabetes Mellitus (DM) is a group of metabolic diseases characterized by an increase in blood sugar levels (hyperglicemia), which occurs due to abnormal insulin secretion and insulin activity or both. This study aims to determine the clinical outcome and treatment profile of Diabetes Mellitus patients in Pasar Rebo Hospital and to know the cost comparison of  DMT2 treatment between patients using human insulin and analog insulin. This analysis uses independent variables such as single human insulin, human insulin + oral DM, human insulin + analog + oral DM, single analog insulin, and insulin analog + oral DM. The dependent variables are clinical outcomes such as GDP, GDPP and HBA1C. The sample of this study were outpatient patients diagnosed with DMT2 with insulin therapy, both insulin analog and human insulin in the period of January 2016 to December 2017 with BPJS guarantee and a minimum of three visits over two years in Pasar Rebo Hospital. The minimum sample calculation is based on the Krejcie-Morgan formula. Data collection is done by using a form that shows the results of therapy with GDP, GDPP and HBA1C, a form that shows the treatment profile of DM, Non DM and Insulin, and the cost profile form. The statistical method used in this study was the Kruskal Wallis non-parametric statistical test. The results showed that the treatment profile based on its type of analog insulin use in 2016 and 2017 amounted to (44,6%) when compared to human insulin which was only (9,8%). The use of short-acting insulin in 2016 was (39,5%) while in 2017 it was more than (55,8%). Lantus insulin the most used brand in 2016 was (42,36%) and Humulin R was most used in 2017 with (36,68%). In clinical outcome of the use of the five types of insulin gives a significant difference to the value of HBA1C but only in the type of human insulin + ADO can make a difference in the value of GDPP. The lowest average cost of insulin is a type of human insulin + ADO that is Rp. 588,541.- Keywords : Diabetes Melitus, Analog Insulin, Human Insulin, BPJS, Outpatients, Clinical Outcomes
PENGEMBANGAN LKS BERBASIS KETERAMPILAN PROSES SAINS (KPS) UNTUK MENINGKATKAN KPS SISWA Sari, Dwi Puspita; Jalmo, Tri; Yolida, Berti
Jurnal Bioterdidik Vol 3, No 10 (2015): Jurnal Bioterdidik
Publisher : Jurnal Bioterdidik

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This study aims were to produce worksheets based on science process skills that effectively improve science process skill of students and determine the response of students. Design of the research was research and development. Test was performed on grade VII1 and VII2 student of SMP Pembangunan Kalianda chosen by purposive sampling. Results from this study showed the average N-gain of science process skill students in the experimental class was higher than the control class, thus the aspect of observing, interpreting, grouping, and communicating. In addition, the average of science process skill students increased from worksheet 1 (25.83%), worksheet 2 (75%), and worksheet 3 (83.33%). Worksheet gained by the student assessment criteria of 95% was attractive to very attractive. Thus worksheet based science process skill on material classification of plant was effectively improve students science process skill and very exciting to be used as one of alternative teaching materials for teachers and students.Penelitian bertujuan untuk menghasilkan LKS berbasis KPS yang efektif meningkatkan KPS siswa dan mengetahui tanggapan siswa. Desain penelitian adalah research and development. Uji coba dilakukan pada siswa kelas VII1 dan VII2SMP Pembangunan Kalianda dipilih secara purposive sampling. Hasil penelitian menunjukkan rata-rata N-gain KPS siswa pada kelas eksperimen lebih tinggi dibandingkan kelas kontrol baik aspek mengamati, menginterpretasi, mengelompokkan, dan mengomunikasikan. Selain itu, rata-rata KPS siswa meningkat dari LKS 1 (25.83%), LKS 2 (75%), dan LKS 3 (83.33%). LKS memperoleh penilaian oleh siswa sebesar 95% kriteria menarik hingga sangat menarik. Dengan demikian LKS berbasis KPS pada materi klasifikasi tumbuhan efektif meningkatkan KPS siswa dan sangat menarik untuk digunakan sebagai salah satu bahan ajar alternatif bagi guru dan siswa. Kata kunci: keterampilan proses sains, klasifikasi tumbuhan, lembar kerja siswa (LKS)
Pengaruh Ekstrak Metanol, Fraksi N-Heksana, dan Fraksi Metanol Biji Pepaya (Carica papaya L.) terhadap Kadar Testosteron dan Bobot Organ Reproduksi Tikus Jantan (Effect of Methanolic Extract, N-Hexanic Fraction, and Methanolic Fraction of Papaya Seed (Ca Sari, Dwi Puspita; Muslichah, Siti; Wiratmo, Wiratmo
Pustaka Kesehatan Vol 2, No 3 (2014)
Publisher : Pustaka Kesehatan

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Papaya seeds (Carica papaya L.) was known have antifertility activity. Testosterone hormone and reproduction organs weight are influence antifertility activity. This study was conducted to compare the effect of the methanolic extract, fraction of n-hexane, and fraction of methanol papaya seeds ( dose 100 mg/kg BW ) with testosterone level and reproduction organs weight parameters of male rats. Measurement of testosterone level by ELISA method. The observation found that the three treatment didn’t decrease reproduction organs weight but decrease testosterone level compared to negative control group. Among the three treatments, metyhanolic extract and methanolic fraction decreased testosterone level. Extract and fraction of methanol alleged alkaloid content of which is known to inhibit development and count of spermatogenic cell.   Keywords: papaya seeds, testosterone, alkaloid, organ
KEBIJAKAN PENGEMBANGAN PERPUSTAKAAN UMUM DI KABUPATEN KARIMUN PROVINSI KEPULAUAN RIAU TAHUN 2011-2013 Sari, Dwi Puspita; ", Hasanuddin
Jurnal Online Mahasiswa (JOM) Bidang Ilmu Sosial dan Ilmu Politik Vol 3, No 1 (2016): WISUDA FEBRUARI 2016
Publisher : Fakultas Ilmu Sosial dan Ilmu Politik Universitas Riau

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This study is intended to determine the role of the Government in implementing the policy, and to know the role of the Office of Library and Regional Archives in implementing the policy. This study focused on Libraries and Library and Archive Office of Karimun regency, whose scope lies in Karimun Riau Islands province, because given the most complex issues contained in the library. These problems include lack of public interest, infrastructure, and human resources. With the formulation of research problems that How public library policy development in Karimun and the factors that affect the implementation of the policy of public library development in Karimun. In the development of the library, the library has been no policy for the region applicable regulations especially those concerning libraries in Karimun, the study aims to identify and analyze policy public library development in Karimun.The research method is qualitative descriptive research data collection is done by observation, interviews and documentation.From the results of research in the field indicates that the Office of Library and Regional Archives Karimun not have a policy of development of a library of standard, so that the public library is in Karimun still referring to existing policies at central and regional administration Riau, a policy that is in Karimun only Local Rules and Regulations in the form of Regents that a technical course. The factors that affect the implementation of the policy of development of public libraries in Karimun, through the theory of former Van Meter and Van Horn, namely: Target and policy standards, performance policies, resources, communication between implementing agencies, Characteristics implementing agencies, economic environment, social and politics and the attitude of the implementers. In this study, the authors conclude that the Local Government does not currently have a policy regarding the library so that local governments do not yet have its own guidelines in terms of policy particularly in view of the public library in Karimun. However, should the regional government should implement a specific policy of the library.Keywords: Policy, Development, Public Library and Government Authority.
ANALISIS NILAI PH DAN KONSENTRASI LOGAM BESI (Fe) PADA MEDIA LAHAN BASAH BUATAN ALIRAN HORIZONTAL BAWAH PERMUKAAN YANG MENGOLAH AIR SALURAN REKLAMASI Nirtha NNPS, Rd. Indah; Sari, Dwi Puspita
EnviroScienteae Vol 14, No 3 (2018): EnviroScienteae Volume 14 Nomor 3, November 2018
Publisher : PS S2 PSDAL PPS ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/es.v14i3.5692

Abstract

One of the impacts of reclamation of swamps is poison substances in the water channels, which can cause to pyrite oxidation, sedimentation and accumulation of toxic substances in secondary channels. The reclamation channel unit in Semangat Karya Village has a water pH of ± 3 and has the iron level of 4.95 mg / l. Based on South Kalimantan Provincial Governor Regulation Year 2007, pH grade and iron concentration are over the quality standard, while the water is consumed by the residents for everyday intentions. One of the technologies that are applied to increase the pH and to minimize the concentration of iron (Fe) is constructed wetland with the horizontal sub-surface flow (CW-HSSF).  The objectives of this research were to study the dynamics of pH and Fe in the media acid sulfate soils mixed with organic fertilizer (bokashi) 10% at CW-HSSF  system using  Purun Tikus (Eleocharis dulcis) and Kalakai (Stenochlaena palustris). The conclusion of this research indicated that pH value and absorption of Fe in CW-HSSF using Purun Tikus (Eleocharis dulcis) was better than Kalakai (Stenochlaena palustris).
Family Conflict and Harmony of Farmers Family Sari, Dwi Puspita; Puspitawati, Herien
Journal of Family Sciences Vol 2, No 1 (2017): Journal of Family Sciences
Publisher : Department of Family and Consumer Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jfs.2.1.28 - 41

Abstract

Conflict in the family is one of the caused of family disharmony. The family harmony can be maintained if family functions were implemented in balanced condition. The purposes of the study were identified family conflict of farmer families and family harmony, to identified conflict family and family harmony’s typologies and to analyzed the correlation between characteristics of family and conflict potential with family harmony. The population in this research wasfarmer families in the Sub-district Cipendawa, District Pacet, Cianjur, West Java, with samples as many as 35 familes. Sampling was selected by census then simple random sampling. The results showed that conflicton farmer families was in low level and family harmony was in high level. The typology of family conflict and family harmony was categorized as Type 3 and Type 4. The results also showed that the older mother, tend to lower the conflict within family. However, there was no significant correlation between family conflict with family harmony.
PERAN PEMBINAAN PERPUSTAKAAN PADA EKSISTENSI PERPUSTAKAAN DESA DI KECAMATAN KUNDURAN KABUPATEN BLORA Sari, Dwi Puspita; Rohmiyati, Yuli
Jurnal Ilmu Perpustakaan Vol 6, No 3 (2017): Agustus 2017
Publisher : Jurusan Ilmu Perpustakaan, Fakultas Ilmu Budaya, Universitas Diponegoro

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Penelitian bertujuan untuk mengetahui gambaran peran pembinaan perpustakaan padaeksistensi perpustakaan desa di Kecamatan Kunduran Kabupaten Blora. Penelitian inimenggunakan desain penelitian kualitatif dengan jenis penelitian deskriptif. Pemilihaninforman dalam penelitian ini menggunakan teknik purposive sampling. Metodepengumpulan data pada penelitian ini adalah wawancara, observasi, dan dokumentasi.Sedangkan analisis data yang digunakan adalah reduksi data, penyajian data, danpenarikan kesimpulan. Berdasarkan penelitian yang dilakukan pada tiga perpustakaan desayang berada di Kecamatan Kunduran Kabupaten Blora, menunjukkan bahwa pembinaanperpustakaan berperan pada eksistensi perpustakaan desa di Kecamatan KunduranKabupaten Blora.Peran pembinaan perpustakaan dapat mengembangkan perpustakaandesa, meningkatkan pengelolaan perpustakaan desa berupa pengolahan bahan pustaka,meningkatkan layanan perpustakaan dengan menggunakan sistem layanan terbuka. Adapunpembinaan yang dilakukan berupa pembinaan administrasi, pembinaan pengolahan bahanpustaka, pembinaan layanan dan pembinaan minat baca.Kemudian dari hasil yangdidapatkan setelah mengikuti pembinaan perpustakaan, pengelola berusaha untukmenunjukkan keberadaan perpustakaan desa dengan cara melaksanakan kegiatan pelatihanserta memperkenalkan perpustakaan secara lisan.
Pengaruh Ekstrak Metanol, Fraksi N-Heksana, dan Fraksi Metanol Biji Pepaya (Carica papaya L.) terhadap Kadar Testosteron dan Bobot Organ Reproduksi Tikus Jantan (Effect of Methanolic Extract, N-Hexanic Fraction, and Methanolic Fraction of Papaya Seed (Ca Sari, Dwi Puspita; Muslichah, Siti; Wiratmo, Wiratmo
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Papaya seeds (Carica papaya L.) was known have antifertility activity. Testosterone hormone and reproduction organs weight are influence antifertility activity. This study was conducted to compare the effect of the methanolic extract, fraction of n-hexane, and fraction of methanol papaya seeds ( dose 100 mg/kg BW ) with testosterone level and reproduction organs weight parameters of male rats. Measurement of testosterone level by ELISA method. The observation found that the three treatment didn’t decrease reproduction organs weight but decrease testosterone level compared to negative control group. Among the three treatments, metyhanolic extract and methanolic fraction decreased testosterone level. Extract and fraction of methanol alleged alkaloid content of which is known to inhibit development and count of spermatogenic cell.   Keywords: papaya seeds, testosterone, alkaloid, organ
PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya L.) TERHADAP EFEK SEDASI PADA MENCIT (Mus musculus L.) DAN SUMBANGANNYA PADA PEMBELAJARAN BIOLOGI SMA Sari, Dwi Puspita; Santoso, Lucia Maria; Madang, Kodri
Jurnal Pembelajaran Biologi: Kajian Biologi dan Pembelajarannya Vol 3, No 2 (2016)
Publisher : fkip unsri

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Abstrak: Penelitian pemanfaatan ekstrak daun pepaya (Carica papaya L.) telah dilakukan untuk mengetahui potensinya dalam memberikan efek sedasi pada mencit (Mus musculus L.). Metode yang digunakan adalah metode eksperimen dengan Rancangan Acak Lengkap (RAL) menggunakan analisis keragaman. Penelitian menggunakan 24 mencit jantan yang terdiri dari empat perlakuan dan  enam ulangan. Perlakuan pemberian dosis  ekstrak daun pepaya terdiri dari 0 mg/10 g BB, 2 mg/10 g BB, 4 mg/10 g BB, dan 8 mg/10 g BB. Data waktu ketahanan mencit di atas hot plate dianalisis dengan perhitungan analisis keragaman dan dilanjutkan dengan Uji Beda Nyata Terkecil (BNT). Hasil penelitian yang didapatkan adalah rata-rata waktu mencit bertahan di atas hot plate yang tertinggi terdapat pada dosis 8 mg/10 g BB yaitu 211,67 detik. Analisis keragaman menunjukan bahwa ekstrak etanol daun pepaya berpengaruh sangat nyata terhadap ketahanan mencit terhadap panas di atas hot plate. Uji BNT menunjukan bahwa terdapat dosis ekstrak etanol daun pepaya yang efektif meningkatkan waktu ketahanan mencit di atas hot plate yaitu  pada dosis 8 mg/10 g BB. Hasil penelitian ini dapat dijadikan sebagai informasi bagi Pembelajaran Biologi SMA kelas XI semester II pada kompetensi dasar 3.8 khususnya mengenai Gangguan pada sistem koordinasi   Kata kunci : Carica papaya L., sedasi, Mus musculus L.
Potensi Kitosan sebagai Edible Coating pada Buah Anggur Hijau (Vitis vinifera Linn) Hilma, Hilma; Fatoni, Ahmad; Sari, Dwi Puspita
Jurnal Penelitian Sains Vol 20, No 1 (2018)
Publisher : Faculty of Mathtmatics and Natural Sciences

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A study has been conducted on influences of various chitosan concentrationas coating and storage time to Vitamin C concentration of green grape (Vitis vinifera L.) by dipping method. This study aims to de-termine the difference of chitosan concentration to physical characteristics, weight loss and vitamin C concen-tration of green grape. Chitosan coating was conducted on 50 grams of green grape by dipping method at var-ious concentration of chitosan that is 0%, 0,5%, 1%, 1,5% and 2% (w / v), kept on variation of one, four and seven day storage time. Determination of vitamin C concentration of green grape was done by UV-Vis spec-trophotometer measured at 256 nm wavelength with regression equation y = 0,0344 x + 0,101 and r = 0,998. Based on statistical test showed that chitosan concentration of 1% (w / v) with 4 days storage time is the most optimum because the chitosan layer is able to close all green grape pores, so the process of anaerobic and CO2 respiration can be inhibited by chitosan solution.