Akhmad Yogi Pramatirta, Akhmad Yogi
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran-Dr. Hasan Sadikin General Hospital

Published : 6 Documents
Articles

Found 6 Documents
Search

Suspectable Risk Factors of Congenital Anomaly in Dr. Hasan Sadikin General Hospital Bandung, Indonesia Yudiasari, Pradistya Syifa; Pramatirta, Akhmad Yogi; Gondodiputro, Sharon
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.152 KB) | DOI: 10.15850/amj.v4n2.1095

Abstract

Background: Congenital anomaly is a disease of structural or functional alteration since birth. The cause of congenital anomaly is genetic, environtment, and unknown. The cause of congenital anomaly is unknown, made congenital anomaly is difficult to detect. Therefore, the objective of this study was to identify the suspectable risk factors of congenital anomaly.Methods: This was a descriptive study. About 78 samples were taken by purposive sampling from medical records of patients with congenital anomaly in pediatric surgery ambulatory unit at Dr. Hasan Sadikin General Hospital (RSHS), Bandung from September to November 2014. From the selected medical records, an interview was carried out to the parents’ patient to identify some suspectable risk factors. The collected data were analyzed and presented in tables.Results: From 78 medical records,  hirschprung disease was the highest among all type of congenital anomaly (29%). The characteristic of congenital anomaly was mothers in the age of 20–35 years (65%), fathers’ age was  more than 20 years old, family history of congenital anomaly was 1%, there was no history of previous congenital anomaly in previous pregnancy, infection history was 3%, history of medication was 11.5%, mother’s BMI was in normal term (18.5─24.9) as much as 65%, no history of radiation, there was no history of chronic alcohol. History of smoking/passive smoking was high (65%).Conclusions: Hirschprung disease is the highest rate disease in congenital anomaly and smoking is a highest suspectable risk factor contribute to congenital anomaly. DOI: 10.15850/amj.v4n2.1095
Suspectable Risk Factors of Congenital Anomaly in Dr. Hasan Sadikin General Hospital Bandung, Indonesia Yudiasari, Pradistya Syifa; Pramatirta, Akhmad Yogi; Gondodiputro, Sharon
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.152 KB) | DOI: 10.15850/amj.v4n2.1095

Abstract

Background: Congenital anomaly is a disease of structural or functional alteration since birth. The cause of congenital anomaly is genetic, environtment, and unknown. The cause of congenital anomaly is unknown, made congenital anomaly is difficult to detect. Therefore, the objective of this study was to identify the suspectable risk factors of congenital anomaly.Methods: This was a descriptive study. About 78 samples were taken by purposive sampling from medical records of patients with congenital anomaly in pediatric surgery ambulatory unit at Dr. Hasan Sadikin General Hospital (RSHS), Bandung from September to November 2014. From the selected medical records, an interview was carried out to the parents’ patient to identify some suspectable risk factors. The collected data were analyzed and presented in tables.Results: From 78 medical records,  hirschprung disease was the highest among all type of congenital anomaly (29%). The characteristic of congenital anomaly was mothers in the age of 20–35 years (65%), fathers’ age was  more than 20 years old, family history of congenital anomaly was 1%, there was no history of previous congenital anomaly in previous pregnancy, infection history was 3%, history of medication was 11.5%, mother’s BMI was in normal term (18.5─24.9) as much as 65%, no history of radiation, there was no history of chronic alcohol. History of smoking/passive smoking was high (65%).Conclusions: Hirschprung disease is the highest rate disease in congenital anomaly and smoking is a highest suspectable risk factor contribute to congenital anomaly. DOI: 10.15850/amj.v4n2.1095
Postpartum Anxiety Factors Involved in Subjects Undergoing Cesarean Section as Analyzed by Zung Self Rating Anxiety Scale Rahmat, Akbar; Saputra, Lucky; Pramatirta, Akhmad Yogi; Sabarudin, Udin; Krisnadi, Sofie Rifayani; Susanto, Herman; Effendi, Jusuf Sulaeman
Indonesian Journal of Obstetrics & Gynecology Science Volume 1 Nomor 1 Maret 2018
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.383 KB)

Abstract

AbstractObjective: postpartum mother who underwent cesarean section may experience anxiety. The risk factors associated with anxiety include age, education and income level, parity, social and cultural factors, delivery methods, as well as the history of pregnancy.Methods: This study used analytic, cross-sectional method. Postpartum mother (n=194) were recruited for this study. All participants consented to fill a questionnaire, to determine the subject’s parameters and anxiety levels. Severity of postpartum anxiety was determined based on the Zung Self-rating Anxiety Scale (SAS). Results: Postpartum anxiety (SAS ≥45) were mostly found in the group experiencing emergency cesarean section (71.13%) compared to the group with scheduled cesarean section (32.1%) (p<0.001). Forty-seven subjects (82.5%) women aged <20 years old experienced postpartum anxiety, while 32.1% women aged ≥20 years old were found to have similar condition (p<0.001). Subjects with lower education levels had a higher prevalence of postpartum anxiety than those with higher education levels (73.4% vs 12.9%, p<0.001). Different income levels  had 47.2% and 46.3% prevalence of postpartum anxiety respectively, but not statistically significant. Conclusion: there was a correlation between anxiety score on women who experienced an emergency and scheduled cesarean section with age and education level.Keywords: Cesarean section, age, education levels, income levels, parity, Zung Self-rating Anxiety ScaleBeberapa Faktor yang Memengaruhi Kecemasan Pasien yang Menjalani Seksio Sesarea dengan Pemeriksaan Zung Self Rating Anxiety ScaleAbstrakTujuan: Kondisi pascaseksio sesarea dapat menimbulkan kecemasan ibu. Faktor yang dapat mempengaruhi timbulnya kecemasan antara lain usia, tingkat pendidikan, tingkat pendapatan, paritas, faktor sosial budaya, faktor jenis persalinan, dan riwayat persalinan yang lalu. Metode: Penelitian ini menggunakan metode analitik cross-sectional. Wanita pasca seksio sesarea yang memenuhi kriteria penelitian (n=194) dengan kuesioner. Tingkat kecemasan dinilai berdasarkan derajat Zung Self-rating Anxiety Scale (SAS).Penelitian dilakukan di RSUP Dr. Hasan Sadikin Bandung, RSUD Ujung Berung, RSKIA Kota Bandung, RSUD Soreang Kabupaten Bandung dari bulan Maret sampai dengan April 2017.Hasil: Penelitian ini menunjukan bahwa kecemasan postpartum (SAS ≥45) lebih banyak ditemukan pada pasien yang menjalani operasi sesar darurat (71,13%) dibandingkan dengan pasien yang telah dijadwalkan terlebih dahulu (32,1%) (p <0,001). Empat puluh tujuh pasien (82,5%) wanita usia <20 tahun mengalami kecemasan pasca melahirkan, sementara 32,1% wanita berusia ≥ 20 tahun ditemukan memiliki kondisi yang sama (p <0,001). Tingkat pendidikan ≤ SLTP memiliki prevalensi kecemasan lebih tinggi dibandingkan > SLTA (73,4% vs 12,9%, p <0,001). Tingkat pendapatan yang berbeda (lebih rendah dari UMR, sama atau lebih tinggi dari UMR) memiliki prevalensi pasca melahirkan sebesar 47,2% dan 46,3%, namun tidak signifikanberbeda  secara statistik. Simpulan: Terdapat perbedaan tingkat kecemasan pasca seksio sesarea pada kelompok  seksio sesarea segera dibandingkan terencana dengan usia dan tingkat pendidikan.Kata kunci: Seksio sesarea, usia, tingkat pendidikan, tingkat pendapatan, paritas, Zung Self-rating Anxiety Scale
Rasio Low Density Lipoprotein dan High Density Lipoprotein pada Preeklamsi Berat dibandingkan dengan Kehamilan Normal di Rumah Sakit Dr. Hasan Sadikin Bandung Amrullah, Amran; Handono, Budi; Pramatirta, Akhmad Yogi
Indonesian Journal of Obstetrics & Gynecology Science Volume 2 Nomor 1 Maret 2019
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2349.542 KB)

Abstract

AbstractObjective: This study aims to distinguish level of  (LDL/HDL)  and Low Density Lipoprotein/High Density Lipoprotein  ratio in severe preeclampsia patient compared to normal pregnancy.Method:  The study design was comparative cross-sectional study with consecutive sampling method that compared the laboratory results of LDL, HDL and ratio LDL/HDL that met the inclusion criteria. Subjects of this study were severe preeclampsia and normal pregnancy patient that fulfilled the inclusion criteria (n=60) in Dr. Hasan Sadikin General Hospital Bandung during August-September 2017.Result: It is revealed that the differences in level of LDL and LDL/HDL ratios in both groups were significant with p value ≤ 0,05. But there were no differences in HDL level. Increased level of LDL/HDL ratio in pregnancy was related to increased risk of preeclampsia with cut-off point> 2,632. If the increased level of LDL/HDL above cut-off point then the insident of severe preeclampsia increased 21,36 times.Conclusion: It was concluded that level of LDL and LDL/HDL ratios in severe preeclampsia were higher than in normal pregnancy. The increased LDL/HDL ratio of > 2.632 increased the risk of severe preeclampsia by 21.36 times.Key words: Preeclampsia, LDL, HDL, LDL/HDL ratioAbstrakTujuan: Penelitian ini adalah untuk mencari perbedaan rasio Low Density Lipoprotein/High Density Lipoprotein (LDL/HDL) pada preeklamsi berat dibandingkan dengan kehamilan normal sebagai faktor risiko timbulnya preeklamsi.Metode: Rancangan penelitian kasus kontrol membandingkan LDL, HDL, dan rasio LDL/HDL penderita preeklamsi berat dan kehamilan normal (n=60) bulan Agustus-September 2017 di Rumah Sakit Dr. Hasan Sadikin Bandung.Hasil: Hasil penelitian didapatkan perbedaan kadar LDL dan rasio LDL/HDL pada kedua kelompok secara bermakna dengan nilai p ≤0,05. Namun tidak didapatkan perbedaan yang bermakna pada kadar HDL. Peningkatan kadar LDL dan rasio LDL/HDL berhubungan dengan peningkatan risiko terjadinya preeklamsi dengan nilai cut-off > 2,632. Bila terjadi peningkatan rasio LDL/HDL diatas nilai cut-off maka risiko tejadinya preeklamsi berat sebesar 21,36 kali.Simpulan: Kadar LDL yang tinggi dan nilai cut-off rasio LDL/HDL >2,632 meningkatkan risiko terjadinya preeklamsi berat 21,36 kaliKata Kunci: Preeklamsi, LDL, HDL, Rasio LDL/HDL
Correlation between fms-Like Tyrosine Kinase-1 (sFlt-1) Cell-Free Messenger RNA Expression and fms-Like Tyrosine Kinase-1 (sFlt-1) Protein Level in Severe Preeclampsia and Normal Pregnancy Gurnadi, Jeffry Iman; Mose, Johanes Cornelius; Handono, Budi; Fauziah, Prima Nanda; Pramatirta, Akhmad Yogi
International Journal of Integrated Health Sciences Vol 3, No 2 (2015)
Publisher : International Journal of Integrated Health Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3043.857 KB)

Abstract

Objective: Preeclampsia is still a problem in Indonesia due to the high maternal and neonatal morbidity and mortality. Placental soluble fms-like tyrosine kinase-1 (sFlt-1), an antagonist of vascular endothelial growth factor (VEGF), and placental growth factor (PIGF), is considered as one of the etiology factors that cause endothelial damage in preeclampsia due to increased sFlt-1 level modulating vascular endothelial integrity. This study aims to analyze sFlt-1 and sFlt-1 mRNA levels in severe preeclampsia and normal pregnancy, and the correlation between both in occurrence of severe preeclampsia.Methods: This is a cross-sectional analytic observational study involving 18 subjects with severe preeclampsia and 19 subjects with normal pregnancy as controls who met inclusion and exclusion criteria. Levels of sFlt-1 and sFlt-1 mRNA were measured with ELISA and RT PCR. Statistical analysis was performed with Chi square test, Fisher’s exact test, T-test, Mann-Whitney test, and Spearman’s rank correlation test.Results: This study showed no significant difference (p>0.05) in characteristics of maternal age, gestational age, and parity in both study groups. Mean level of sFlt-1 mRNA in severe preeclampsia was higher (6.3404 pg/mL) compared to its level in normal pregnancy (5.9701 pg/mL). There is a not significant (p>0.05) positive correlation between sFlt-1 mRNA with sFlt-1 level in normal pregnancy, and a not significant (p>0.05) negative correlation between both level in severe preeclampsia.Conclusions: sFlt-1 mRNA levels in severe preeclampsia are higher than its level in normal pregnancy. There is no correlation between sFlt-1 mRNA level and sFLt-1 protein level in severe preeclampsia. There is a not significant positive correlation between sFlt-1 mRNA with sFlt-1 level in normal pregnancy, and a not significant negative correlation between both in severe preeclampsia.Keywords: Normal pregnancy, severe preeclampsia, sFlt-1 mRNA DOI: 10.15850/ijihs.v3n2.586
HUBUNGAN KADAR ASAM URAT, LAKTAT DEHIDROGENASE, ASPARTAT AMINOTRANSFERASE SERUM PENDERITA PREEKLAMSI BERAT DISERTAI KOMPLIKASI DAN TANPA KOMPLIKASI Apriadi, Galih; Handono, Budi; Pramatirta, Akhmad Yogi; Effendi, Jusuf S.; Madjid, Tita Husnitawati; Pribadi, Adhi
Indonesian Journal of Obstetrics & Gynecology Science Volume 3 Nomor 1 Maret 2020
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (868.094 KB)

Abstract

Latar Belakang: Preeklamsi berat merupakan salah satu penyebab tersering mortalitas dan morbiditas pada ibu dan bayi. Morbiditas dan mortalitas pada ibu akan semakin meningkat karena terjadinya komplikasi. Komplikasi preeklamsi berat yang terjadi dapat berupa komplikasi kardiovaskular, hati, otak dan ginjal. Tujuan penelitian ini untuk mencari perbedaan kadar asam urat, laktat dehidrogenase atau LDH dan aspartat aminotransferase atau AST pada serum penderita preeklamsi berat disertai komplikasi dan tanpa komplikasi dan mengukur kuatnya hubungan peningkatan kadar asam urat, LDH dan AST dengan peningkatan risiko terjadinya komplikasi pada pasien preeklamsi berat.Metode: Rancangan penelitian ini adalah penelitian comparative cross sectional dengan metode consecutive sampling yang membandingkan hasil laboratarium asam urat, LDH, AST dari subjek penelitian yang memenuhi kriteria inklusi. Subjek penelitian adalah penderita preeklamsi berat disertai komplikasi dan preeklamsi berat tanpa komplikasi (n=68). Penelitian dilakukan di Rumah Sakit Dr. Hasan Sadikin Bandung dan rumah sakit jejaring pada bulan November-Desember 2016.Hasil : Hasil penelitian didapatkan perbedaan kadar asam urat, LDH dan AST pada kedua kelompok secara bermakna dengan nilai p ? 0,05. Peningkatan kadar asam urat, LDH dan AST berhubungan dengan peningkatan risiko terjadinya komplikasi pada preeklamsi berat dengan nilai cut off kadar asam urat > 6,5 mg/dL sebesar 33 kali, LDH > 573 U/L sebesar 8,95 kali dan AST > 30 U/L sebesar 5,19 kali. Jika terjadi peningkatan seluruh kadar asam urat, LDH dan AST diatas nilai cut off maka risiko terjadinya komplikasi pada preeklamsi berat sebesar 98,1%.Kesimpulan: Penelitian ini menyimpulkan kadar asam urat, LDH, AST pada preeklamsi berat disertai komplikasi lebih tinggi dibandingkan preeklamsi berat tanpa komplikasi dan peningkatan kadar asam urat, LDH, AST berhubungan dengan peningkatan risiko terjadinya komplikasi pada preeklamsi berat.