Rulina Suradi, Rulina
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CLINICAL AND LABORATORY FEATURES OF CHILDHOOD SYSTEMIC LUPUS ERYTHEMATOSUS AND ITS COURSE IN DEPARTMENT OF CHILD HEALTH, CIPTO MANGUNKUSUMO HOSPITAL, JAKARTA Munasir, Zakiudin; Mariana, Tuty; Suradi, Rulina
Paediatrica Indonesiana Vol 41 No 7-8 (2001): July 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.4.2001.214-24

Abstract

A descriptive, retrospective study has been performed among 33 children with SLE during the period of January 1986 to December 1999 in Department of Child Health, Cipto Mangunkusumo Hospital. The results of the present study show that SLE in childhood was more commonly found in girls than in boys, with a ratio of 4.5: 1. The mean age of onset was 10.5 years and the mean age of diagnosis was 10.9 years, most frequently observed in the age of > 10 years and rarely found in the age of < 5 years. The time interval between the time of onset and time of diagnosis ranged from 1 to 24 months and the most frequent interval was 1-3 months. The most common initial symptoms were prolonged fever, rash on the skin and face, and athralgia. In its natural history of the disease, kidneys, skin/mucous membrane and joints are the most frequent organs involved. Most of the SLE patients develop anemia. Positive anti ds-DNA, ANA and decreased levels of C3 and C4 respectively in 28 (28/31), in 29 (29/30), in 25 (25/33), and in 19 (19/27) cases. LE cells were encountered only in four (4/17) cases.  Out of 11 cases upon which renal biopsies were done, the most common histological features were mesangeal glomerulonephritis (class II) and diffuse proliferative glomerulonephritis (class IV). The mean time interval between the onset and renal complication manifestations was 6.96 months, cardiac complication was 16.77 months, central nerve system was 22.71 months and lungs were 25.0 months. Duration of illness of patients with SLE ranged from 2 to 175 with the mean of 31.3 months. The causes of death were mostly due to gastrointestinal bleeding and renal failure.
CLINICAL FEATURES AND SURVIVAL PATTERN OF CENTRAL NERVOUS SYSTEM LEUKEMIA IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA Pusponegoro, Hardiono D.; Z., Moeslichan M.; Kaban, Risma K.; Suradi, Rulina; Windiastuti, Endang
Paediatrica Indonesiana Vol 41 No 9-10 (2001): September 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.5.2001.247-52

Abstract

Infiltration of leukemic cells into the central nervous system (CNS) is one of the causes of neurological disorders in patients with acute lymphoblastic leukemia (ALL) that worsen the prognosis. This retrospective cohort study aimed to review the clinical manifestations of children with CNS leukemia, their survival pattern and the role of early CNS leukemial. The survival curve was developed by Kaplan-Meier method, while the comparison of survival curves was done with log-rank test. Among 128 new ALL patients, 23 (18.0%) patients suffered from CNS leukemia, while 13 (10.2%) suffered from early CNS leukemia and 10 (7.8%) suffered from relapsing CNS leukemia. CNS leukemia was more common in male, in those aged less than 2 years, in those with white blood cell (WBC) count above 50,000/ìl, and in patients type FAB-L2 ALL. The clinical manifestations most commonly found were decrease of consciousness (61%), vomiting (48%), cranial nerve palsy (44%), seizures (39%), and headache (26%). Relapsing CNS leukemia was more common in high risk (12.5%) compared with standard risk leukemia (5.7%). Patients with early CNS leukemia had a lower survival rate than those without early CNS leukemia (p = 0.0005). The percentage of patients with early CNS leukemia surviving up to 3 years was 26%. We conclude that early CNS leukemia could cause low survival ALL patients.
TOPIRAMATE AS AN ADJUNCTIVE THERAPY IN CHILDREN WITH INTRACTABLE EPILEPSY Pusponegoro, Hardiono D.; Handayani, Tri Lestari; Mangunatmadja, Irawan; Widodo, Dwi Putro; Suradi, Rulina
Paediatrica Indonesiana Vol 42 No 11-12 (2002): November 2002
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi42.6.2002.287-91

Abstract

Background Epilepsy is a chronic disease that requires antiepileptic drugs (AEDs). Only 60-70% of new patients could be controlled effectively by standard AEDs and this stimulates the search for new, more effective and well-tolerated AEDs.Objective To asses the efficacy and safety of topiramate, as an adjunctive therapy to standard AEDs for children with intractable epilepsy.Methods This was an open label, parallel group study. Forty children with at least 4 seizures during a 4-week baseline period were randomly assigned to topiramate (n=20) or control group (n=20). In the topiramate group, the drug was given in adjunct to AEDs for  2-week titration dosage continued with a 12-week stabilization period, while the control group received only AEDs adjusted to their clinical responses.Results Mean reduction from baseline in monthly seizures frequency was significantly greater in the topiramate group (88.6% vs. 25%; P=0.030). Other variable of efficacy was significantly different (e"50% reduction in seizures: 14/20 vs. 6 /20; P=0.049). Adverse effects of topiramate, such as decreased weight, paresthesia, somnolence, diarrhea, fever, aggressive reaction and flushing, were temporary and mild.Conclusion Results of this trial strongly suggested that topiramate is effective and well tolerated in reducing seizures of intractable epilepsy.
EARLY KANGAROO MOTHER CARE VS. CONVENTIONAL METHOD IN STABILIZING LOW BIRTH WEIGHT INFANT: PHYSIOLOGIC PARAMETERS (PRELIMINARY REPORT) Suradi, Rulina; Yanuarso, Piprim B.; Sastroasmoro, Sudigdo; Dharmasetiawani, Nani
Paediatrica Indonesiana Vol 42 No 11-12 (2002): November 2002
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi42.6.2002.273-9

Abstract

Background Kangaroo mother care (KMC) has been accepted as an effective method in nursing low birth weight infant (LBWI). However, the application of this method in the early life of infants has not been studied in Indonesia.Objective To evaluate some physiologic parameters of LBWI treated with early KMC compared to conventional method.Methods This was a randomized clinical-trial, which compared early KMC to conventional method in stabilizing LBWI in the first 4 hours of life. All LBWI (birth weight 1500-2499 g) bom at Cipto Mangunkusumo Hospital and Budi Kemuliaan Matemity Hospital Jakarta were recruited consecutively in the period of November 2001 until March 2002. The inclusion criteria were spontaneous delivery, APGAR scores 13t and 5th minute 37, and parental consent.Results Sixty-four subjects distributed evenly into early KMC group and control group. One subject in the KMC group and three subjects in the control group were excluded due to respiratory distress. The mean birth weight was 2091 (SO 299.4) g in the KMC group and 2184 (SO 214.9) g inthe control group. The mean gestational-age in both groups was 35.6 (SO 3.0) weeks. There were no statistical differences in mean temperature (P=0.281), heart rate (P=0.956), and respiratory rate (P=0.898) between the two groups during the first 4 hours of life. We found a larger proportion of infants reaching the temperature of 36.5QC in the KMC group, especially at one hour (49% vs. 7%); the difference of proportion was 0.42 (95%CI 0.22 to 0.61).Conclusion Early KMC method is proved to be as safe as conventional method in stabilizing healthy LBWI.
Efficacy of oral erythromycin to enhance feeding tolerance in preterm infants Sukmawati, Made; Rohsiswatmo, Rinawati; Suradi, Rulina; Gayatri, Pramita
Paediatrica Indonesiana Vol 57 No 3 (2017): May 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (117.76 KB) | DOI: 10.14238/pi57.3.2017.154-9

Abstract

Background Feeding intolerance is a common condition that affects preterm infants. Erythromycin is a prokinetic agent used to treat feeding intolerance, but its efficacy remains inconclusive.Objective To evaluate the effectiveness of oral erythromycin to enhance feeding tolerance in preterm infants.Methods This prospective, randomized controlled trial in preterm infants was conducted at Sanglah Hospital, Denpasar, Bali, from June 2015 to January 2016. Eligible infants were randomized to receive either 12.5 mg/kg/dose oral erythromycin or a placebo, every 8 hours. The primary outcome was the time to establish full enteral feeding. The secondary outcomes were body weight at full enteral feeding and length of hospital stay.Results Of 62 initial subjects, 3 infants dropped out of the study. Thirty infants were given erythromycin and 29 infants were given placebo. The baseline characteristics of the two groups were similar, with mean of gestational ages of 31.4 (SD 1.7) weeks in the erythromycin group and 32.4 (SD 2.2) weeks in the placebo group. The median times to reach full enteral feeding did not significantly differ between the two groups, with 10 (SD 5.3) days in the erythromycin group vs. 8 (SD 6.5) days in the placebo group (P=0.345). Also, median body weights at full enteral feeding and lengths of hospital stay were not significantly different between the two groups.Conclusion Erythromycin of 12.5 mg/kg/dose every 8 hours as prophylactic treatment does not significantly enhance feeding tolerance in preterm infants. Median body weights at full enteral feeding and length of hospital stay are not significantly different between the erythromycin and placebo groups.
PLAIN ABDOMINAL RADIOGRAPH APPEARANCE IN CHILDREN WITH ABDOMINAL PAIN Firman, Kemas; Darussalam, Dora; Suradi, Rulina
Paediatrica Indonesiana Vol 42 No 9-10 (2002): September 2002
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi42.5.2002.212-6

Abstract

Background Abdominal pain is a common condition in children. Plain abdominal radiograph is recommended routinely in the evaluation of children with abdominal pain.Methods A retrospective study was done to evaluate radiographic abnormalities in children with abdominal pain at the Department of Child Health Cipto Mangunkusumo Hospital from January 1, 1994 to December 31, 1998.Results Of the 76 patients with abdominal pain, there were 38 females and 38 males. Forty-five patients were in the >5-12 years age group. Thirty-five out of 76 patients showed radiographic abnormalities. The most common radiographic abnormality was stones (found in 13 patients), followed by uneven distribution of bowel air in 8 patients.Conclusion A plain abdominal radiograph is still required as a diagnostic tool for children with abdominal pain, especially in the acute stage.
Saat Terbaik Pemberian Suplementasi Zat Besi pada Bayi 0 Bulan sampai 6 Bulan Ringoringo, Harapan Parlindungan; Wahidiyat, Iskandar; Sutrisna, Bambang; Setiabudy, Rahayuningsih; Suradi, Rulina; Setiabudy, Rianto; Bardososono, Sapatawati
Sari Pediatri Vol 10, No 3 (2008)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp10.3.2008.163-70

Abstract

Latar belakang. Anemia defisiensi besi (ADB) merupakan salah satu masalah kesehatan gizi di Indonesia. Survei kesehatan rumah tangga (SKRT) tahun 2001 menunjukkan prevalensi ADB pada bayi 0-6 bulan 61,3%.Tujuan. Mengetahui berapa insidens defisiensi besi dengan atau tanpa anemia, dan kapan mulai terjadi deplesi besi atau defisiensi besi sebelum terjadi ADB pada bayi berusia 0-6 bulan.Metode. Desain penelitian adalah studi kohort prospektif dengan pembanding eksternal. Di antara 211 bayi yang ikut penelitian, terdiri dari 143 bayi yang lahir dari ibu tanpa anemia dan 68 bayi yang lahir dari ibu dengan anemia. Pemeriksaan darah tepi lengkap, gambaran darah tepi, saturasi transferin (ST) dilakukan saat bayi berusia 0, 1, 2, 3, 4, 5, dan 6 bulan. Diagnosis ADB berdasarkan 1) kadar Hb <14g/dL untuk usia 0-3 hari, <11g/dL untuk usia 1 bulan, <10g/dL untuk usia 2-6 bulan, 2) mikrositik dan atau hipokrom, 3) kadar Hb meningkat setelah diberi terapi besi, 4) RDW >14%, 5) Indeks Mentzer >13; 6) Indeks RDW >22,0. Deplesi besi bila ST <30% untuk usia 0-1 bulan, ST <21% untuk usia 2-6 bulan. Defisiensi besi bila ST <20% untuk usia 0-1 bulan, ST <16% untuk usia 2-6 bulan.Hasil. Insidens deplesi besi, defisiensi besi, ADB berturut-turut 28,0, 27,0, dan 40,8%; artinya 95,8% bayi mempunyai status besi bermasalah. Insidens deplesi besi, defisiensi besi, ADB paling tinggi pada bayi berusia 0 bulan, berturut-turut 9,5, 14,2, dan 11,8%.Kesimpulan. Insidens deplesi besi, defisiensi besi, ADB paling tinggi pada bayi berusia 0 bulan. Suplementasi zat besi elemental dengan dosis 1 mg/kg/hari hendaknya diberikan pada semua bayi aterm sejak lahir.
Tata laksana Bayi dari Ibu pengidap HIV/AIDS Suradi, Rulina
Sari Pediatri Vol 4, No 4 (2003)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (540.454 KB) | DOI: 10.14238/sp4.4.2003.180-5

Abstract

Sejak diidentifikasi kasus AIDS pada tahun 1981 di Los Angeles, kasus AIDS melandadunia. Di Asia Tenggara jumlah kasus yang dilaporkan pada tahun 1999 adalah 134.671kasus. Di Indonesia secara kumulatif tercatat dari September 1987 sampai denganDesember 2001 terdapat 1904 kasus HIV positif dan 615 kasus AIDS. Transmisi vertikaldari ibu ke bayi dapat secara transmisi intra-uterin, intrapartum dan melalui ASI. Denganberbagai cara misalnya persalinan melalui bedah kaisar dan penggunaan obat obatantirertroviral terjadi pengurangan transmisi vertikal secara intra-uterin dan intrapartum,tetapi transmisi melalui ASI tidak dapat dicegah. Tata laksana bayi dari ibu pengidapHIV/AIDS adalah suportif, meliputi pemberian imunisasi rutin, pemantauanpertumbuhan dan pemeriksaan darah. Bila timbul gejala segera obati dengan obatantiretroviral.
Spesifitas Biologis Air Susu Ibu Suradi, Rulina
Sari Pediatri Vol 3, No 3 (2001)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp3.3.2001.134-40

Abstract

Air susu mamalia adalah species specific (komposisi masing-masing susu mamalia sangatberbeda). Sebagaimana susu sapi adalah makanan terbaik untuk anak sapi maka ASIadalah makanan terbaik untuk bayi manusia, juga untuk bayi yang lahir kurang bulan.Penambahan atau pengurangan zat di dalam susu sapi agar dapat ditolerir oleh bayimanusia berupa susu formula memerlukan penelitian yang canggih yang perlumempertimbangkan bukan hanya zat gizinya tetapi seyogianya segala komponen yangada di dalam ASI. Perubahan komposisi ASI yang disesuaikan dengan masa kehamilan,usia bayi dan cara bayi menyusu tidak dapat ditiru oleh susu formula apalagi keuntunganlain seperti, mencegah penyakit bayi dan ibu serta keuntungan psikologis dan ekonomi.
Model Skoring Untuk Memprediksi Anemia Defisiensi Besi pada Bayi 0-6 Bulan Ringoringo, Harapan Parlindungan; Wahidiyat, Iskandar; Sutrisna, Bambang; Setiabudy, Rahayuningsih; Suradi, Rulina; Setiabudy, Rianto; Bardososono, Saptawati
Sari Pediatri Vol 10, No 5 (2009)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp10.5.2009.338-44

Abstract

Latar belakang. Anemia defisiensi besi (ADB) merupakan salah satu masalah kesehatan gizi di Indonesia. DataSKRT tahun 2001 menunjukkan prevalensi ADB pada bayi 0-6 bulan 61,3%. Belum dijumpai pemeriksaanlaboratorium sederhana yang dapat memprediksi seorang bayi berusia 0-6 bulan menderita ADB.Tuj uan. Mencari model skoring untuk memprediksi ADB pada bayi 0-6 bulan.Metode. Desain penelitian adalah studi kohort prospektif dengan pembanding eksternal. Ada 211 bayi yangikut penelitian, terdiri dari 143 bayi yang lahir dari ibu tanpa anemia dan 68 bayi yang lahir dari ibu dengananemia. Pemeriksaan darah tepi lengkap, gambaran darah tepi, feritin, sTfR dilakukan saat bayi berusia 0bulan, 1, 2, 3, 4, 5, 6, dan 12 bulan. Diagnosis ADB berdasarkan 1) kadar Hb <14g/dL untuk usia 0-3 hari,<11g/dL untuk usia 1 bulan, <10g/dL untuk usia 2-6 bulan, 2) gambaran darah tepi mikrositik dan atauhipokrom, 3) kadar Hb meningkat setelah diberi terapi besi, 4) RDW >14%, 5) Indeks Mentzer >13; 6)Indeks RDW >220.Hasil. Faktor risiko terjadi ADB pada bayi berusia 0-6 bulan adalah diet ibu dan jenis kelamin bayi. Berdasarkanfaktor risiko dibuat model skoring dan klasifikasi risiko untuk memprediksi seorang bayi berusia 0-6 bulanakan menderita ADB atau tidak.Kesimpulan. Model skoring untuk memprediksi ADB pada bayi berusia 0-6 bulan dapat digunakan untukdeteksi dini ADB. (
Co-Authors Abdul Latief Agus Firmansyah Alan Roland Tumbelaka, Alan Roland Ali Sungkar Arwin A.P. Akib, Arwin A.P. Asril Aminullah Bambang Sutrisna Bambang Tridjaja, Bambang Benita Deselina, Benita Bergh, Anne-Marie Boris Januar, Boris Bulan G. Munthe Chair, lmral Corry S. Matondang Daisy Widiastuti, Daisy Dewanto, Naomi Dewanto, Naomi E.F. Djajadiman Gatot Dora Darussalam, Dora Dwi Prasetyo Dwi Putro Widodo, Dwi Putro Endang Windiastuti Fatmawaty Fatmawaty, Fatmawaty Gipson, Reginald Gulardi H. Wiknjosastro Hadi Pratomo Harapan Parlindungan Ringoringo, Harapan Parlindungan Hardiono D. Pusponegoro, Hardiono D. Hartono Gunardi Hindra I. Satari, Hindra I. Irawan Mangunatmadja, Irawan Irma Rochima Puspita, Irma Rochima Iskandar Wahidiyat, Iskandar Kemas Firman Lineus Hewis, Lineus Maria Abdulsalam, Maria Mariana, Tuty Monitja, H.E. Nani Dharmasetiawani Nastiti Kaswandani Partini P Trihono, Partini P Piprim B. Yanuarso, Piprim B. Pramita Gayatri, Pramita Pringgardini, Keumala Rahayuningsih Setiabudy, Rahayuningsih Rahmat, Dedy Rianto Setiabudy Ridwan M. Thaha, Ridwan M. Rifan Fauzie, Rifan Rinawati Rohsiswatmo Risma K. Kaban Rogers-Bloch, Quail Ronny Suwento, Ronny RR, Graham Sapatawati Bardososono, Sapatawati Saptawati Bardosono Saptawati Bardososono, Saptawati Sidi, Ieda Poernomo Sigit Siti B. Kresno Situmeang, Esther H. Sjawitri P. Siregar, Sjawitri P. Soedjatmiko Soedjatmiko Soesilo, Ommy A Sri Rezeki Hadinegoro, Sri Rezeki Sri Rezeki S. Hadinegoro, Sri Rezeki S. Sri S Nasar, Sri S Sudigdo Sastroasmoro Sujana Jatiputra Sukman Tulus Putra, Sukman Tulus Sukmawati, Made Suparno Suparno Suryapranata, F.J. Suryono, Isnani Taifur, WEnny Lazdya Tan, Anthony Taralan Tambunan Tarigan, Lukman Theresia Santi, Theresia Tri Lestari Handayani, Tri Lestari Tri Sunarti Wahyutami, Tri Sunarti Uhudiyah, Uut Wisnumurti, Dewi Anggraeni Wisnuwardhani, Siti D. Yeni Rustina Z., Moeslichan M. Zakiudin Munasir