Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan
Vol 1, No 1 (2015): Pharmauho

Uji Toksisitas Akut Ekstrak Metanol Daun Keji Beling (Strobilanthes crispus BI.), Batang dan Bunga Jarak Tintir (Jatropha multifida L.) terhadap Larva Artemia salina Leach dengan Metode Brine Shrimp Lethality Test (BSLT)

Hamsidi, Rini (Unknown)
Wahyuni, Wahyuni (Unknown)
Sani, Asrul (Unknown)



Article Info

Publish Date
12 Apr 2015

Abstract

Research on the acute toxicity test of methanol extracts of keji beling leaves (Strobilanthes crispus BI.), stems and flowers of jarak tintir (Jatropha multifida L.) against Artemia salina Leach larvae using Brine Shrimp Lethality Test method (BSLT) had been carried out. The purpose of this study was to determine the potency of acute toxicity of methanol extract which were shown by LC50 value. In this research, the sample methanol were obtained from a previous research. Acute toxicity tests was conducted to determine the LC50 values of plant extracts according to the method of Brine Shrimp Lethality Test. Results of the research showed methanol extract of keji beling leaves were not toxic with LC50 value 4427,95 μg/mL, meanwhile stems and flowers of jarak tintir had low toxicity with LC50 225,09 and 253,26 μg/mL, respectively. The value of LC50 influenced by the content of secondary metabolites in plants.Keywords : Acute toxicity test, Brine Shrimp Lethality Test, LC50, J. multifida, S. crispus

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Journal Info

Abbrev

pharmauho

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

Description

Fakultas Farmasi Universitas Halu Oleo mengelola dan menerbitkan Jurnal Farmasi, Sains dan Kesehatan Pharmauho yang merupakan Jurnal ilmiah yang menyajikan artikel orisinal tentang pengetahuan dan informasi riset atau aplikasi dan perkembangan terkini yang berhubungan dengan kesehatan. Jurnal ini ...