Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan
Vol 1, No 2 (2015): Pharmauho

Aktivitas Antioksidan Senyawa Asam 5(E)-Eikosenoat dari Batang Tanaman Polygonum pulchrum Bl

Malaka, Muhammad Hajrul (Unknown)
Yodha, Agung Wibawa Mahatva (Unknown)
Azhar, Muhammad (Unknown)
Hamsidi, Rini (Unknown)
Sahidin, Sahidin (Unknown)



Article Info

Publish Date
16 Sep 2015

Abstract

Isolation and identification of secondary metabolite stem bark of Polygonum pulchrum and its antioxidant activity were done. Extraction was performed by maceration using methanol solvent. The separation and purification obtained by using vacuum liquid chromatography (VLC), radial chromatography (RC) and monitored by thin layer chromatography (TLC). Identification of isolated compounds determined by spectroscopy method i.e. FT-IR, 1D-NMR (1H, 13C-NMR and DEPT) and 2-D NMR (HMQC and HMBC). White solid compound was isolated and characterized as 5(E)-eicosenoic acid. Antioxidant was analyzed towards DPPH (1,1-diphenyl-picrilhydrazil). The compound showed that has antioxidant potency with IC50 value at 348.10 µM.Keywords: Polygonum pulchrum, 5(E)-eicosenoic acid, antimicrobial, antioxidant 

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Journal Info

Abbrev

pharmauho

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

Description

Fakultas Farmasi Universitas Halu Oleo mengelola dan menerbitkan Jurnal Farmasi, Sains dan Kesehatan Pharmauho yang merupakan Jurnal ilmiah yang menyajikan artikel orisinal tentang pengetahuan dan informasi riset atau aplikasi dan perkembangan terkini yang berhubungan dengan kesehatan. Jurnal ini ...