Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal
Vol 29, No 2 (2012)

Aktivitas Antifungi Ekstrak Etanol Daun Salam (Syzygium polyanthum (Wight) Walp.) terhadap Pertumbuhan Jamur Candida albicans secara in vitro

Fitriani, Any (Unknown)
Hamdiyati, Yanti (Unknown)
Ria Engriyani, Ria Engriyani (Unknown)



Article Info

Publish Date
10 May 2012

Abstract

Antifungal activity of the ethanol extract of bay-leaf (Syzygium  polyanthum (Wight) Walp.) against growth of the fungus Candida albicans in vitro has been conducted. Leaves of S. polyanthum has been known to have potential as antifungal for skin fungal pathogen. This study aims to determine antifungal activity of the ethanol extract of S. polyanthum leaves against growth of C. albicans.  Activity test was done by disc-diffusion  method and macro-dilution. This study used concentrations of ethanol leaf extract of S. polyanthum of 0.5%, 1%, 1.5%, 2%, and 2.5% (w/v). Negative control using 1% DMSO and positive controls using ketoconazole 30 mg/mL. The results shows that ethanol extract of leaves of S. polyanthum have activity as an antifungal. Ethanol extract of leaves of S. polyanthum based on the results of GCMS analysis of compounds containing chemical compounds such as terpenoids and fatty acids. Ethanol extract of leaves of S. polyanthum showed the highest inhibition zone diameter at a concentration of 1% (w/v) of 9.32 ± 0.21 mm. Value of Minimum inhibitory Concentration (MIC) for ethanol leaf extract of S. polyanthum present in a concentration of 0.5% (w/v) and the value of Minimum Fungicidal Concentration (MFC) present in a concentration of 1% (w/v).

Copyrights © 2012






Journal Info

Abbrev

biosfera

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science

Description

Majalah Ilmiah Biologi Biosfera : A Scientific Journal merupakan peer reviewed jurnal yang diterbitkan oleh Fakultas Biologi Universitas Jenderal Soedirman. Media ini mewadahi hasil-hasil penelitian di bidang biologi tropika yang terbit tiga kali setahun (Januari, Mei, ...