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Paediatrica Indonesiana
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 7 Documents
Search results for , issue " Vol 34 No 1-2 (1994): January 1994" : 7 Documents clear
Cyclosporin-A Treatment in Steroid Nonresponsive Nephrotic Syndrome Wirya, IGN Wila; Tambunan, Taralan; Alatan, Husein
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.615 KB) | DOI: 10.14238/pi34.1-2.1994.1-7

Abstract

Fifteen patients with steroid nonresponsive nephrotic syndrome (NS) aged 4-16 years received oral cyclosporin-A (CyA) for 12 weeks. Nine of the patients were boys. Out of the 15 patients, 7 were frequent relapsers, 3 were steroid dependents, 4 were steroid resistants and one with toxic steroid. After 12 weeks of CyA treatment;, 6 patients showed complete remission, 7 showed partial remission, and 2 patients did not respond at all. Side effects observed were slight renal function impairment, gingival hyperplasia, and a hump on the breast; all disappeared gradually after stopping CyA. Patients with total remission experienced relapse 2 to 12 months after discontinuation of CyA, while patients with partial remission experienced relapse 2 weeks to 3 months after CyA was discontinued A tentative conclusion can be drawn that CyA is a good alternative in the treatment of idiopathic NS, especially in steroid dependent patients who are at risk of developing steroid toxicity. CyA represent a major advance in the treatment selected SN patients who have failed with the conventional modes of therapy.
Physical Growth of Children with Ventricular Septal Defect Madiyono, Bambang; Soelaeman, Eva Jeumpa; Oesman, Ismet N.; Sastroasmoro, Sudigdo
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1007.195 KB) | DOI: 10.14238/pi34.1-2.1994.16-25

Abstract

We conducted a prospective study on children with ventricular septal defect (VSD) for assessing the physical growth status, establishing the determinants of growth, and determining the effect of natural history on growth. There were 46 VSD patients and 30 controls aged 1-5 years. We divided the subjects into two groups; group A consisted of 32 VSD patients and 16 controls aged 12-35 months, group 8 comprised 14 VSD patients and 14 controls aged of 36-60 months. A simple hemodynamic scoring system was created to determine the correlation between physical growth and severity of hemodynamic alteration, using 10 findings based on history, physical, and non-invasive examinations. Body weight and height, and arm circumference were measured every 3 months up to 12 months. The growth status correlated well with the hemodynamic scores. Body weight and arm circumference were more affected than body height Physical growth disturbance was observed in high score patients at the beginning, and became more evident at the end, of the study. In low score patients and circumference was slightly affected at the beginning of the study, while body weight was slightly disturbed after 9 months of observation.
Antibiotic Therapy for Invasive Bacterial Diarrhea Ismail, Rudi; Bakri, Achiriul; Nazir, Mohammad; Haridawati, Ryanto
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (971.208 KB) | DOI: 10.14238/pi34.1-2.1994.26-37

Abstract

To evaluate the effectiveness of the standard practice of antibiotic prescribing in diarrheal diseases (DD) at Palembang General Hospital, we performed this single blind clinical trial. Subjects were children with DD, without E. histolytica.. or G. Iamblia in their stool, 6 to 59 months of age, seen at the OPD from May 20, 1991 until March 31, 1992. Antibiotic treatment (AT) was given to the treated group (n=289), and was withheld from the control group (n=298). The effectiveness of antibiotic treatment was measured by rate of reconsultation, need for subsequent AT, duration of diarrhea, vomiting, and fever as measured by home visitors. The treated group has a significantly shorter duration of diarrhea and a significant difference in the need for additional AT. Subjects whose diarrhea persist more than 7 days were significant statistically only in bloody diarrhea and in subjects whose fecal leukocytes were more than 9 per high power field. Profuse diarrhea and mother's anxiety were the main reasons for further consultation, which were strikingly greater in control than in treated group. Mothers seeked reconsultation 12.5 times more often for bloody diarrhea and 19.5 times for mucoid diarrhea plus fever. This study reconfirmed that AT in DD shortens the duration of diarrhea, diminishes the rate of reconsultation, and need for subsequent antibiotics in bloody and mucoid diarrhea.
Association between Acid-Base Balance and Asphyxia in Newborn Infants Harahap, Sari Leyli; Harahap, Chairul Adillah; Sulastri, Sri; Yoel, Chairul; Raid, Noersida
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.241 KB) | DOI: 10.14238/pi34.1-2.1994.38-43

Abstract

We performed a prospective study on the association between acid-base balance and asphyxta based on Apgar scores in 45 newborn babies admitted to the Division of Perinatology, Pirngadi Hospital, Medan, from January 1 to February 28, 1993. Blood gas analysis was done on blood obtained from umbilical artery. Based on 1st and 5th minutes Apgar scores, 40 (88.9%) and 21 babies (46.7%}, respectively, had asphyxia. Relation to acid-base balance was determined with the sensitivity of the 5th minute Apgar score in predicting acidotic states. It was found that Apgar score had sensitivity of 57.7% and specificity of 68.4% in predicting the acidotic states. Apgar score of > 7 was unable to. exclude the possible acidosis in 45% of cases (negative predictive value 54.1%). Gestational age had no influence on Apgar Scores. Apgar score was more sensitive to eliminate suspected acidosis in term neonates than in preterms. We recommend to perform umbilical arterial blood gas analysis to determine acidotic state in high risk newborn infants.
Blood Gas Analysis in Neonatal Tetanus Soetomenggolo, Taslim S.; Widodo, Dwi Putro; Passat, Jimmy; Ismael, Sofyan
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.487 KB) | DOI: 10.14238/pi34.1-2.1994.44-7

Abstract

We reviewed the results of arterial blood gas analysis in 127 patients with neonatal tetanus on admission, and in 52 of such patients on the day before they died. All patients were hospitalized at the Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta. On admission, most patients showed uncompensated metabolic acidosis. The mortality of patients wjth pH ofless than 7 was 100%. There was no significant difference between the mortality of patients with pH 7.35-7.45 and those with pH of less than 7.35. Analysis of acid-base balance indicated that ventilatory fw1ure was the most common finding in 52 patients who subsequently died. We recommend using intravenous fluid containing a combination of 5% dextrose and sodium bicarbonate with 4 : 1 (vol/vol) ratio from the fust day of hospitalization to reduce the possibility of the development of ongoing metabolic acidosis in patients with neonatal tetanus. Maintaining adequate ventilation is mandatory ln such patients.
Risk Factors for Nosocomial Infections in Neonatal Intensive Care Unit Sitomorang, Ingrid Rita; Garna, Herry
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (759.979 KB) | DOI: 10.14238/pi34.1-2.1994.48-56

Abstract

We report our study to determine factors associated with increased nosocomial infections in neonates hospitalized in NJCU, from January until December, 1992. A total number of 116 infants were studied, 68 (58.6%) of them were male, and 101 (87 .1 %) were less than 6 days old. Forty six infants (39.8%) had a birth weight of< 1500 g, 27 (23.3%) between 1500-1999 g, 14 (12.1%) between 2000-2499 g, 27 (23.2%) >2500 g, and 2 (1.7%) were unknown. A total number of64 infants (55.2%) had more than 1 infections, yielding 103 episodes of infection, giving an incidence of 88.8% infection rate. The significant risk factor for nosocomial infections was length of hospital stay. Age, birth weight, gestational age, APGAR scores, use of nasogastric tube or intravenous line, were not statistically significant risk factors. Use of nasogastric tube was associated with increased nosocomial gastroenteritis, compared with use of intravenous lines.
Diabetes Insipidus in A 8-Year Old Balinese Boy Prayoga, AAN; Westra, IN; Suraatmadja, Sudaryat
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (474.537 KB) | DOI: 10.14238/pi34.1-2.1994.57-61

Abstract

We report a case of diabetes insipidus in a 8 years old Balinese boy. The diagnosis was based on clinical features, laboratory findings, and a good result to chlorpropamide therapy. Common differential diagnoses, i.e., were hypercalcemia, potassium deficiency, psychogenic polydipsia, and diabetes mellitus, could be excluded. The treatment of first choice for diabetes mellitus is desmopressin acetate; however, since the drug was not available, we gave chlorpropamide instead. The patient responded well to 125 mg of clorpropamide twice daily.

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