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Paediatrica Indonesiana
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 12 Documents
Search results for , issue " Vol 41 No 1-2 (2001): January 2001" : 12 Documents clear
Autoimmune hemolytic anemia warm-antibody type (Warm AIHA) in an 8-year-old Balinese girl Yasa, Putu Tri; Mudita, Ida Bagus; Santoso, Hendra; Suraatmadja, Sudaryat
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.704 KB) | DOI: 10.14238/pi41.1.2001.64-8

Abstract

A case of autoimmune hemolytic anemia warm antibody type A (warm AIHA) in an 8-year-old Balinese girl was reported. The diagnosis was established based on clinical features, laboratory findings including positive Coombs'  test positive. The etiology was probably primary or Idiopathic. The child was transfused with packed red cells and treated with oral prednisone. The response of the treatment was good and she experienced complete remission. The prognosis in patients with idiopathic warm AIHA are unpredictable. The girl underwent further follow-up in the child hematologic division every two weeks.
Alagille syndrome: Review of 14 patients Pujiarto, Purnamawati S.; Smith, Arnold L.
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (677.426 KB) | DOI: 10.14238/pi41.1.2001.47-55

Abstract

Alagille syndrome (AGS) Is a common form of familial intrahepatic choleslasis, an autosomal dominant disorder due to defects in Jagged1 gene. It Is characterized by at least 3 of 5 mator features. We reviewed two groups of patients with AGS. Group 1 comprised 12 AGS patients, retrospectively studied (1995-1996), in the Gastroenterology Department, Royal Children's Hospital, Melbourne. Group 2 comprised 2 AGS patients, prospectively studied since 1999, in The Pediatric Hepatology Division, Cipto Mangunkusumo Hospital, Jakarta. Prolonged cholestasis is the most common feature at presentation (12 patients). All these 12 subjects developed pruritus and xanthoma of varying degree. Osteopenia occured in 6 patients, 2 patients experienced fractures. AGS facies was noted In aH 14 subjects. Heart anomaty was found in 10 patients, vertebral anomaly in 6 patients, and posterior embryotoxin in 10 patients. Common additional features were growth and mental retardation in 10 and 8 patients, respectively. Liver biopsy was able to confirm the diagnosis as young as age 2 months. Death occurred in 2 patients due to liver failure and hemorrhagic pneumonia. Liver transplant was done in 1 patient due to poor quality of life (severe pruritus, xanthoma, recurrent fractures). Affected family members were strongly presumed in 8 patients. In conclusion, AGS should be considered in babies with chronic Intrahepatic cholestasls, especially it associated with pruritus. Liver biopsy Is the most sensitive diagnostic testing which will prevent unnecessary surgical intervention due to biliary atresia mimicry.
Denver Developmental Screening Test in two-year old infants delivered by vacuum extraction Sembiring, Meriah; Iskandar, Iskandar; Syarifuddin, Amir; Saing, Bistok
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.995 KB) | DOI: 10.14238/pi41.1.2001.27-32

Abstract

The aim of this study was to determine the developmental retardation of infants of two years of age who were delivered by vacuum extraction. This cross-sectional study examined 44 infants delivered by vacuum extraction, comprising 25 males and 19 females who were born in Tembakau Deli and St. Elizabeth Hospitals, between August 1993 until February 1994. The examination included interview and physical examination in the patient's house. Chi-square statistics analysis was used with a significant level of 95% (1'=0.05). The results showed Ihat of the 44 infants delivered by vacuum extraction. 28 (32%) had had were found with mild asphyxia, while 2 infants (5%). whose mothers work as private clerk and entrepreneur, had development retardation. We concluded that there was no significant difference in development between infants delivered by vacuum extraction and those who were born spontaneously. Developmental retardation was found in infants whose mothers lack time to communicate.
Pedigree analysis of glucose-6 phosphate dehydrogenase (G6PD) deficiency of a Javanese Chinese family in Indonesia Ugrasena, IDG; Shirakawa, Taku; Nishiyama, Kaoru; Matsuo, Masafumi
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.1.2001.56-9

Abstract

The molecular and pedigree analyses in a Javanese Chinese family were carried oul on glucose-6-phosphate dehydrogenase deficiencies. By method of  MPTP scanning without the sequencing steps, those variants could be confirmed. Two out of three sons were clinically jaundiced at birth due to G6PD deficiency and identified to have a G to T nucleotide change al 1376th nucleotide 01 the G6PD gene (GI376T), corresponding to G6PD Canton. Another son was also identified to have a C to T nucleotide change at 1311st nucleotide 01 the G6PD gene (CI311T), corresponding to a Silent mutation. Their father was normal, but their mother obsorved to have the heleromutation 01 G1376T (G6PD Canton and C1311T (a Silent mutation).
Relationship between the general condition of acute lymphoblastic leukemia patients with remission rate and convulsion as an adverse effect chemotherapy Andid, Rusdi; Nurdiani, Nurdiani; Lubis, Bidasari; Sutjipto, Adi
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.223 KB) | DOI: 10.14238/pi41.1.2001.33-7

Abstract

A retrospective study on the relationship between the general condition of acute lymphoblastic leukemia patients with remission rale and convulsion as an adverse effect of chemotherapy was conducted in leukemia patients of the hematology-oncology subdivision, Departmenl of Child Health, Medical School, University of North Sumatra, Medan. Of 114 children with acute lymphoblastic leukemia, 81 (71.05%) received chemotherapy, 31 patients among them was in good general condition. Remission rate of the 31 patients was 80.6% (25 children). Whereas in the remaining 50 patients, the remission rate among them was 84% (42 patients). There was no significant relationship between their general condition to the recurrence rate of acute lymphoblastic leukemia patients who had been administered chemotherapy during induction phase. Convulsion was found In 2 cases, due to CNS leukemia.
Hypertension due to renal artery stenosis Albar, Husein; Rahman, Haeriah; Rauf, Syarifuddin
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.376 KB) | DOI: 10.14238/pi41.1.2001.60-3

Abstract

A case of a 12-year-old boy with renal artery stenosis as a cause of hypertension is presented. The diagnosis of renal artery stenosis was established based on the bruit heard over costovertebral angle and the increased plasma rennin secretion, and further confirmed by angiogram finding. The detection of bruit, either on the abdomen or costovertebral angle, in association Indones with hypertension should initially lead to the consideration of the presence of renal artery stenosis.
Evaluation of cardiac murmurs in 8647 children at primary school-age children in the Province of Malatya, Eastern Turkiye Pac, Feyza Aysenur; Karabiber, Hamza; Kilic, Ayhan; Kutlu, Onur; Yakinci, Cengiz; Egri, Mucahit
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (420.305 KB) | DOI: 10.14238/pi41.1.2001.42-6

Abstract

We assessed prospectively the prevalence 01 pathologic and Innocent murmurs in childhood, to determine the efficacy of clinical evaluation, to compare the results of physical examinations performed by pediatricians and pediatric cardiologists and echocardiographic evaluations, and to contribute to the determination of the limits of echocardiography indications in children with murmurs. A number of 8647 children, aged 6.5-15 years, 4092 females, 4455 males in ten different primary schools belonging to different socioeconomic levels in Malatya, Eastern Turkey. Those children with a murmur were evaluated by a pediatric cardiologist. Chest X-ray, electrocardiography, and echocardlography were obtained in all subjects having a murmur. The results of physical examinations performed by the pediatricians and the pediatric cardiologist were compared, and the final diagnoses were reached by evaluation of chest X-ray, ECG and chocardiography. The incidence of Innocent murmurs was found to be 3.4% and that of pathological murmurs 0.54% In the population eximaned. The statistical comparison of the results revealed that pediatricians have a tendency toward Innocent murmurs in the interpretation of murmurs (p<0.05). There was not a statistically significant difference between the results of physical examinations of the pediatric cardiologist and the results of echocardlographic examination. Pediatricians can diagnose pathologic cases with a sensitivity of 63.8% whereas pediatric cardiologist could diagnose those cases with a sensitivity of 95.7% and specificity of 99.7%. Our findings support the policy that children with a cardiac murmur should be referred to a pediatric cardiologist, in order to verify clinical diagnosis.
Covert bacteriuria in schoolchildren Tambunan, Taralan; Kumalawati, Yuli; Trihono, Partini P.; Giantiti, Astuti; Kadim, Muzal; Irawani, Vera
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.965 KB) | DOI: 10.14238/pi41.1.2001.38-41

Abstract

Covert bacteriuria is defined as significant bacteriuria detected during a screening program, This study was done as a pari of pilot program held by Medical School University of Indonesia namely Community Health Program. The screening was carried out at four Primary School al Cibubur Subdistrict Eastern Jakarta. The population target was focused on children at the third, four1h and fifth grade from each school. Screening urinalyses include examinatiOfl for the presence of glucose, protein, blood and bacteria. There were 460 children enrolled to this study, but only 449 cases were eligible for assessment comprising 217 males and 232 females aged ranged between 7.4-14.1 years. Covert bacteriuria were found in ten cases (2.22%), comprising five males and females consecutively. Antibiotics were not given. Repeated urine culture done two weeks later revealed that six cases cured spontaneously, four other cases still showing bacteriuria although all cases remain asymptomatic. We conclude that covert bacteriuria in schoolchildren is a benign condition, most of them are spontaneously cured without antibiotic treatment. This conclusion is in accordance with the opinion of most authors that screening for bacteriuria in healthy children does not have a place in any age group including schoolchildren.
Blood lipid of preadolescent boys of well-to-do families Munir, Muzief; Darmoprawiro, Sudiro
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (591.434 KB) | DOI: 10.14238/pi41.1.2001.19-26

Abstract

Coronary heart disease is presently one of the leading causes of death In adults in many countries, including in Indonesia. It is well known that elevated levels of cholesterol in children are closely associated with hypercholesterolemia and coronary heart disease in adult life. This study was conducted in an attempt to find a preliminary insight of the magnitude of the problem of hypercholesterolemia In children In Indonesia as a developing country. The blood lipid levels of 54 preadolescent boys from well-Io-do families were analyzed. Two-third of those children were shown to have elevated blood cholesterol level, and even one third or 16 out of 54 preadolescents boys investigated suffered from hypercholesterolemia. We conclude that elevated blood cholesterol level is frequently found among large-framed and obese Indonesian children.
Nutritional status of underfive children of less privileged families in Medan Hutagalung, Indra B.; Lubis, Bangun; Ridwanto, Ridwanto; Hakimi, Hakimi; Hamid, Endang D.
Paediatrica Indonesiana Vol 41 No 1-2 (2001): January 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (552.498 KB) | DOI: 10.14238/pi41.1.2001.11-8

Abstract

A cross sectional study was done on 94 under five children taken from Keluarga Pra-sejahtera (pre-prosperous family=-pre-PF) and Keluarga Sejahtera Tahap-1 (prosperous family phase-I=PF-I) in the East Medan subdistrict, municipality of Medan in period of August 1995 up to February 1996. The aim of the study was to measure nutritional status of under five children in both groups. There were 94 under five children in group of ore-PF and 94 under five children in group of PF-l. It was found that the nutritional status of both groups was significantly different. Significant difference was also noted when they were classified according to father's occupational status and father's education level. However when they were grouped according to maternal education, number of children in the family, and occurrence of disease in the previous month no significant difference was detected.

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