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Paediatrica Indonesiana
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 6 Documents
Search results for , issue "Vol 28 No 9-10 (1988): September 1988" : 6 Documents clear
RECENT ADVANCES IN THE MANAGEMENT OF END-STAGE RENAL DISEASE (ESRD) IN CHILDREN Fine, Richard N.
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (435.109 KB) | DOI: 10.14238/pi28.9-10.1988.218-22

Abstract

It has been almost 20 years since the initial report were published detailing the use of the dual treatment modalities of dialysis and renal transplantation to treat children with ESRD. During this time, the outlook for the infant, child and adolescent with ESRD has changed dramatically from abject pessimism to cautious optimism. Initially, hemodialysis was the principle dialytic technique utilized; however, intermittent peritoneal dialysis was used occasionally in selected centers. The latter required less technical expertise, but necessitated considerably more dialysis time and was significantly less efficient at alleviating the clinical and biochemical consequences of uremia.
HYPOVOLEMIC SHOCK COMPLICATING NEPHROTIC SYNDROME IN A CHILD Kosnadi, Lydia; W., Rochmanadji; Sumantri, A. G.; Trimulyo, Trimulyo; Anwar, M. Rofiq
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (471.015 KB) | DOI: 10.14238/pi28.9-10.1988.209-13

Abstract

The fundamental abnormality in nephrotic syndrome is the structural and electrochemical changes that have been documented to occur in the glomerular basement membrane lead to proteinuria. It is the proteinuria itself which most likely causes hypoalbuminemia and associated complications such as infections, hypercoagulability and hypovolemia. Hypovolemia may cause postural hypotension, acute renal failure, circulatory collaps or sudden death. An eleven-year-old boy was referred to the Child Health Department of Dr. Kariadi Hospital Semarang with a diagnosis of corticosteroid resistant nephrotic syndrome and acute renal failure. Physical examination showed a severely ill boy with general edema, shock, hemoconcentration, hypoalbuminemia, hypercholesterolemia, massive proteinuria and disturbed renal function. The treatment consisted of infusion of dextrose 10% followed by human plasma and furosemide to restore plasma volume and enhance urine production. Two days later he was in better condition,  normovolemia, slight edema, good diuresis, but his blood pressure increased, and ophtalmologic examination supported the diagnosis of grade I hypertensive retinopathy. Intravenous clonidine and furosemide were given and were very effective. Kidney biopsy revealed minimal lesion with slight proliferation.
CONSERVATIVE TREATMENT OF CHRONIC RENAL FAILURE (CRF) Fine, Richard N.
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (285.786 KB) | DOI: 10.14238/pi28.9-10.1988.214-7

Abstract

The infant, child and adolescent who has irreversible impairment of renal function, regardless of the specific etiology, invariably experiences a progressive decline in glomerular filtration rate (GFR) over time. This decline in GFR can be attributed to an unremitting attack on the remaining unaffected nephrons by, the primary disease process such as in a patient with acquired immune complex disease, but the reasons for the progressive decline in GFR in patients with congenital diseases are more difficult to identify. Currently the hypothesis attributing the decline in GFR to damage to the remaining intact nephrons resulting from hyperperfusion is receiving increasing attention. Creation of CRF in the rat model by 7/8 nephrectomy leads to a rapid decline in GFR and focal glomerulosclerosis (FGS) in the previously normal glomeruli. This lesion of FGS is presumably a result of hyperperfusion of the remaining normal nephrons in order to compensate for the reduction in functioning renal mass.
COLLOID ONCOTIC PRESSURE IN CHILDREN WITH NEPHROTIC SYNDROME Tambunan, Taralan; Alatas, H.; Wirya, I. G. N. Wila; Harmanses, S.; Chair, I.; Simanjuntak, R.
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (581.566 KB) | DOI: 10.14238/pi28.9-10.1988.200-8

Abstract

To evaluate the correlation between plasma protein concentration and colloid oncotic pressure (COP) and their influence on clinical symptom of edema, we studied 30 children with nephrotic syndrome (NS). Total plasma protein concentration (TP), albumm, globulin and COP were measured in all patients in edema forming state (EF) and m steady state phase (SS), except for COP, only 16 samples in SS phase. COP TP plasma albumin and globulin contents in EF group were 8. 7 ± 2. 7 mmHg, 4.07 '± 0.68 g/dl; 2.57 ± 0.50 g/dl and 1.51 ± 0.32 g/dl, respectively. In SS group these figures rose significantly to 16.7 ± 3.9 mmHg for COP; 5. 70 ± 0.99 g/dl for TP; 3.46 ± 0.52 g!dl and 2.06 ± 0.56 g/dl for plasma albumin and globulin, respectively. We also found the high correlation both between COP and albumin content (r= +0.58; p < 0.01) and between COP and TP (r= +0.54; P < 0.01) . A strong negative correlation was also found between COP and the degree of edema (r = _ 0.55; p <0.01). On the other hand a very low grade correlation was noticed between plasma albumin content and  the degree of edema (r= - 0.26; P < 0.05) and no correlation at all was found between edema and TP (r= - 0.19; P > 0.05). We conclude that COP has the highest correlation with plasma protein concentration and the degree of edema, and can be used as a diagnostic tool. It is even more sensitive and simple compared with the TP or albumin content determination.
STUDIES OF BLOOD PRESSURE AND PREVALENCE OF HYPERTENSION IN SCHOOLCHILDREN IN JAKARTA Wirya, I. G. N. Wila; Alatan, Husein; Tambunan, Taralan; Harmanses, S.; Windiastuti, Endang
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (455.088 KB) | DOI: 10.14238/pi28.9-10.1988.183-91

Abstract

Blood pressure measurement was done on 4983 school children of 6 - 18 years schoolchildren was at random so that the sample population represented the children in Jakarta. The incidence of hypertension in this study is about 3.11 %, of which most are found at the age of 15 years.
DESCRIPTION OF RENAL BIOPSY IN FREQUENTLY RELAPSING AND CORTICOSTEROID NON RESPONSIVE NEPHROTIC SYNDROME IN CHILDHOOD Bahrun, D.; Nazir, M.; N., K. Yangtjik
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (503.299 KB) | DOI: 10.14238/pi28.9-10.1988.192-9

Abstract

A study of 71 children with nephrotic syndrome admitted to the Department of Child Health, Medical School, Sriwijaya University Palembang General Hospital between November 1981 and November 1983 has been reported. Of the 71 children, there were 50 (70.4%) boys and 21 (29.6%) girls, in which 31 were less than 6 years of age. During the first eight weeks complete rem1sswn was found in 66 patients. The other five were steroid resistant. Among the 66 patients who responded to steroid, 61 had remission with the first 4 weeks. Further observation up to two years, 3 patients were still in remission, 36 had one relapse and 22 had frequent relapses. The other 5 patients, who had remission on the second 4 weeks, one had one relapse, two had frequent relapses and the other two were not available for follow up. Renal biopsy was performed in 31 patients. The representative results of the renal biopsy were found in only 20 patients : Eleven patients showed minimal change nephrotic syndrome (MCNS). Ten of these patients had frequent relapses while one patient was steroid resistant. Two had renal insufficiency. Three patients had focal glomerulosclerosis (FGS); two of them were frequently relapsing patients and the other one had steroid resistant. Four patients had mesangial proliferative glomerulonephritis (Mes. PGN). All of them had frequent relapses. One patient with diffuse proliferative glomerulonephritis (DPGN) was steroid resistant. One patient with crescentic glomerulonephritis (CrGN) was also steroid resistant.

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