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Journal of Medicine and Health
ISSN : 24425227     EISSN : -     DOI : -
Core Subject : Health, Science,
Journal of Medicine and Health (JMH) is an open access journal (OAJ), a periodic scientific publication biannually online published on February and August; using review and screening system by peer group reviewer. JMH receives original research articles which related to medicine, health, new developing therapy from traditional medicine or herbs and developing clinical therapy. JMH also receives otiginal review articles, case report, continuing medicine and health study. Articles should be written in good English or Indonesian language.
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Articles 194 Documents
PENINGKATAN FUNGSI ATENSI DAN MEMORI JANGKA PENDEK PADA WANITA DEWASA MUDA DENGAN ANSIETAS SETELAH TERAPI MEWARNAI Krisnanda, Moses A; Hasianna, Stella T; Limyati, Yenni
Journal of Medicine and Health Vol 2 No 5 (2020)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v2i5.2030

Abstract

Kecemasan dapat mempengaruhi fungsi atensi dan memori. Tujuan penelitian ini adalah untuk mengetahui pengaruh terapi mewarnai terhadap peningkatan fungsi atensi dan memori jangka pendek pada wanita dewasa muda dengan ansietas. Penelitian ini menggunakan metode analitik eksperimental kuasi yang bersifat komparatif dengan rancangan pre-test dan post-test. Data yang diukur adalah atensi (skor Stroop test) dan memori jangka pendek (skor Scenery Picture Memory Test / SPMT). Subjek penelitian ini adalah 25 orang mahasiswi dengan ansietas (skor A pada kuesioner Depression Anxiety Stress Scale / DASS-42 ?8). Hasil penelitian rerata skor Stroop test pada pre-test dan post-test adalah 136,20 dan 72,60 detik, sedangkan rerata skor SPMT pada pre-test dan post-test adalah 17,88 dan 20,92. Penelitian ini menggunakan uji analisis statistik Wilcoxon dengan nilai ?=0,05 dan menunjukkan hasil nilai p 0,000 untuk skor Stroop test dan SPMT (sangat signifikan). Simpulan penelitian ini adalah terapi mewarnai meningkatkan fungsi atensi dan memori jangka pendek pada wanita dewasa muda dengan ansietas.   Kata Kunci: terapi mewarnai, atensi, memori jangka pendek, kognitif, ansietas
PENGARUH BEE POLLEN TERHADAP KADAR SGOT, SGPT DAN GAMBARAN HISTOPATOLOGIS HEPAR PADA TIKUS YANG DIINDUKSI PAKAN TINGGI LEMAK Prahastuti, Sijani; Ladi, Jeanny E; Dewi, Kartika; Albertina, Felicia; Imam, Muhammad K
Journal of Medicine and Health Vol 2 No 5 (2020)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v2i5.2040

Abstract

Dislipidemia  merupakan faktor risiko Non Alcoholic Fatty Liver Disease menyebabkan kerusakan hepatosit.  Bee pollen mempunyai efek hipolipodemik,  anti inflamasi. Tujuan penelitian   menganalisa  pengaruh Bee Pollen terhadap kadar SGOT, SGPT, apakah setara dengan simvastatin dan pengaruhnya terhadap gambaran histopatolgis hepar tikus wistar jantan yang diinduksi pakan tinggi lemak (PTL). Metode penelitian eksperimental laboratorium sungguhan, 30 ekor tikus dibagi 6 kelompok (n=5). PTL diberikan 28 hari , Simvastatin dan  Bee Pollen diberikan hari ke-15 hingga 28. SGOT , SGPT diperiksa hari ke-0, 15, 29  dengan spektrofotometri (340 nm). Pemeriksaan histopatologis hepar hari ke-29. Hasil penelitian : Kadar SGOT, SGPT  antara Bee pollen 1 (18 mg/kgBB/hari) ,  2  (36 mg/kgBB/hari), 3 (72 mg/kgBB/hari) dengan PTL  terdapat perbedaan sangat bermakna. Kadar SGOT Bee Pollen 1,2,3 dengan  simvastatin tidak terdapat perbedaan bermakna.  Kadar SGPT Bee Pollen 3 dengan simvastatin tidak terdapat perbedaan bermakna. Pengukuran derajat sel bengkak keruh, inflamasi portal, bridging fibrosis, periportal fibrosis antara Bee Pollen 1, 2 dengan PTL  terdapat perbedaan bermakna, antara Bee Pollen 3  dengan PTL berbeda sangat bermakna. Simpulan :  Bee Pollen dapat  menurunkan kadar SGOT, SGPT,  potensinya setara dengan simvastatin dalam menurunkan kadar SGOT,  SGPT dan memperbaiki gambaran histopatologis hepar tikus galur Wistar jantan yang diinduksi pakan tinggi lemak.   Kata kunci : Dislipidemia, Bee pollen,  SGOT, SGPT, Gambaran Histopatologi
UJI AKTIVITAS ANTIBAKTERI EKSTRAK METANOL, EKSTRAK FRAKSI N-HEKSAN DAN EKSTRAK N-HEKSAN DAUN FILICIUM DECIPIENS TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS DAN BAKTERI BACILLUS SUBTILIS Mahyuni, Siti; Sofihidayati, Trirakhma
Journal of Medicine and Health Vol 2 No 5 (2020)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v2i5.2004

Abstract

Ekstrak etanol tanaman Filicium decipiens diketahui memiliki aktivitas antibakteri kuat terhadap Staphylococcus aureus, namun belum ada penelitian aktivitas antibakteri ekstrak F. decipiens dengan pelarut berbeda. Tujuan penelitian ini mengetahui aktivitas anti bakteri ekstrak metanol, fraksi n-heksan ekstrak metanol dan ekstrak n-heksan daun F. decipiens terhadap bakteri S. aureus dan bakteri Bacillus subtilis. Ekstraksi dilakukan dengan metode soxletasi menggunakan pelarut metanol dan n-heksan. Uji aktivitas anti bakteri dilakukan dengan mengukur konsentrasi hambat minimum (KHM) dan lebar daerah hambat (LDH). Hasil penelitian menunjukkan bahwa ekstrak metanol tidak memiliki aktivitas baik terhadap bakteri S. aureus maupun terhadap B. subtilis.  Ekstrak n-heksan yang difraksinsi dari ekstrak metanol tidak memiliki aktivitas terhadap B. subtilis namun menunjukkan aktivitas sedang terhadap bakteri S. aureus dengan LDH tertinggi 9 mm pada konsentrasi ekstrak 40%. Ekstrak n-heksan memiliki aktivitas antibakteri yang sangat kuat terhadap  S. aureus dengan diameter hambat mencapai 21 mm pada konsentrasi 30% dan menunjukkan aktivitas kuat terhadap  B. subtilis dengan diameter hambat 10 mm pada konsentrasi 30%. Dapat disimpulkan bahwa ekstrak n-heksan F. decipiens memiliki aktivitas antibakteri paling kuat dibandingkan dengan ekstrak metanol dan ekstrak fraksi n-heksan.   Kata kunci: Filiciums decipiens, Staphylococcus aureus, Bacillus subtilis, ekstrak n-hexan, ekstrak metanol 
The Effect of Chicken (Gallus gallus domesticus) Eggshell’s Powder towards Wound Healing of Incision Wound on Male Swiss-Webster Mice Nugraha, Rahman A.; Pramono, Harijadi; Wahyudianingsih, Roro
Journal of Medicine and Health Vol 1, No 4 (2016)
Publisher : Maranatha Christian University

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Abstract

Domestic chicken eggshells contain calcium and protein that could be useful in wound healing process. This research was conducted to determine whether domestic chicken eggshells can accelerate wound healing. Twenty one male Swiss-Webster mice  with 2 cm incision were divided into 3 groups. Negative control group were given Carboxymethyl cellulose 1% (CMC), positive control group were given feracrylum 1% (FER), and the eggshells group given domestic chicken eggshells powder (KT). Treatment and data mesurement was measured every day until  the 7th day. On the 7th  day the average length of the wound were analyzed and the skin tissue is taken for microscopic examination. Data analyzed using one-way ANOVA followed by Post Hoc Least Significant Difference (LSD) with p=0,05. On macroscopic examination, there were  highly significant differences between KT compared to CMC and highly significant differences between KT compared to FER. the average length of wound on the 7th day on KT 0,63 cm shorter than CMC 1,07 (p=0,000) and FER 0,81 cm (p=0,003). On microscopic examination, the degree of reepithelization on KT groups are severe, moderate for collagen density, fibroblasts density, subepithelial neutrophil density, degree of edema, and mild for angiogenesis. We conclude domestic chicken eggshells powder can accelerate wound healing. Key words: domestic chicken eggshells, incision wound, wound healing
Snake-Bite with Disseminated Intravascular Coagulation (DIC) and Stage II Hypertension Subroto, Hendra; Lismayanti, Leni
Journal of Medicine and Health Vol 1, No 5 (2017)
Publisher : Maranatha Christian University

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Abstract

Snake-bite is an important medical emergency case and caused of many hospitaladmission especially in the rural area, forests, plantations and swamps. Despite its importance,there have been fewer proper data of snake-bite incidence in Indonesia. World HealthOrganization estimate that at least 421,000 envenomings and 20,000 deaths from snakebitesoccur each year, especially in South and South East Asia and sub-Saharan Africa. The authorsreport a case of a 76-year-old man came to Hasan Sadikin Hospital with chief complaint woundin his right hand and right forearm from snake-bite. Snake-bites can cause DIC because thevenom activates the coagulation system and cause fibrinolysis which occurs in less than 24hours. Laboratory results, we found abnormalities such as anemia, thrombocytopenia,hypofibrinogenemia, and increased levels of D-dimer. Patients were treated for 8 days and thenallowed to go home. Snake-bite is an occupational disease of farmers, plantation workers,herdsmen, fishermen, other. Snake bite cases require prompt and comprehensive managementso as to minimize the possibility of disability and death.Keywords: snake bite, DIC, hypertension
Comparison of Students’ Characteristics, Self-Motivation, and Readiness of Self-Directed Learning Implementation among Medical Students at Maranatha Christian University Gunanegara, Rimonta F; Wahid, Mardiastuti H; Widyahening, Indah S
Journal of Medicine and Health Vol 1, No 5 (2017)
Publisher : Maranatha Christian University

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Abstract

Self-Directed Learning (SDL) is an important skill that must be achieved by medical students.The aim of this study is to identify the level of self-motivation and SDL readiness in the medicalstudents as well as to identify factors affecting SDL. This is is a mixed method research,involving first-year and clinical year medical students. A quantitative research is conducted bydistributing self-motivation (MSLQ) and SDL questionnaire (SDLRS). A total sampling isapplied to select the respondents. Furthermore, focus group discussion (FGD) on students andtutors/preceptors is carried out. Informants are chosen by purposive sampling method. Thisresearch reveals that most of medical students have a good level of self-motivation but a lowlevel of SDL readiness. Nevertheless, the mean scores of SDL readiness in both groups showsno significant differences. The research also identifies four major factors affecting the SDLreadiness, namely the students’ characteristics, learning process, the role of tutors/preceptorsand supporting facilities for learning. There is no significant difference between SDL readinessof the first-year and clinical year of medical students. Unprepared students’ characteristics,sub-optimal learning process, unsupported role of tutors/preceptors and inadequate learningresources are found to be the mayor factors influencing SDL readiness.Keywords: self-directed learning readiness; self-motivation; problem-based learning
The Effect of Tempe Dietary Intake on Plasma Glucose Level in Elderly Patients with Type 2 Diabetes Mellitus Puspasari, Grace; Dillon, Drupadi; Budiman, Budiman
Journal of Medicine and Health Vol 1, No 6 (2017)
Publisher : Maranatha Christian University

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Abstract

The aim of the study was to investigate  the effect of daily intake of 100 grams tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial. Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study subjects were assigned to two groups using block randomization. All subjects had to take diabetic regiment with calorie and macronutrient following diabetic recommendation diet. The treatment group (n=16) received tempe, while control group (n=14) received legumes other than tempe. Fasting plasma glucose level (FPG) was assessed before and after intervention. Unpaired t test and Mann Whitney were used to analyzed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Both group were comparable in age, gender, BMI, calorie and macronutrient intake before treatment. Fat, fiber, and isoflavone intake were significantly higher in treatment group compare to control group. Decrease in FPG after intervention were observed but were statisticaly insignificant. In conclusion daily intake of 100 grams tempe for four weeks did not decrease FPG.  Keywords: elderly, plasma glucose level, tempe, type 2 diabetes
Protective Effect of Ethanol Extract Tempuyung Leaf (Sonchus arvensis L.) Against Gentamicin Induced Renal Injury Viewed from Blood Ureum Level Imelda, Imelda; Azaria, Cherry; Lucretia, Teresa
Journal of Medicine and Health Vol 1, No 6 (2017)
Publisher : Maranatha Christian University

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Abstract

Acute renal injury is characterized by decrement of glomerular filtration rate (GFR), resulting in nitrogen metabolic end product retention such as blood ureum. Aminoglycoside nephrotoxic injuries are common in elderly, with mortality rate 50-70%. Tempuyung has been empirically used in relieving renal problems as it contains several active antioxidants. This study aimed to analyze the protective effect of ethanol extract tempuyung leaf (EET) against gentamicin induced renal injury viewed from blood ureum level. The method used was true experimental laboratory, 16 wistar male rats, divided into 4 groups (n=4): negative control group (CMC), positive control group (Gentamicin 80 mg/kgBW), 1st treatment group (EET 100 mg/kgBW + Gentamicin), 2nd treatment group (EET 200 mg/kgBW + Gentamicin) for ten days. On the 11th day, blood serum were taken and the ureum level were analyzed. Data was analyzed by ANOVA and post hoc LSD test. Result showed positive control group had the highest blood ureum level (29.50  1.29 mg/dL) compared to negative control group (14.25  1.26 mg/dL), 1st treatment group (26.50  0.58 mg/dL), and 2nd treatment group (22.25  1.26 mg/dL) with significance difference (p<0,001). In conclusion, the result suggested the protective effect of EET against gentamicin induced renal injury.Keywords: acute renal injury, gentamicin, glomerular filtration rate, tempuyung, ureum
Volume 1 Topic Index Team, Editorial
Journal of Medicine and Health Vol 1, No 6 (2017)
Publisher : Maranatha Christian University

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Abstract

Volume 1 Topic Index
Bcl-2 Immunoexpression as Radiotherapy Response Predictor in Undifferentiated Nasopharynx Carcinoma Damayanti, Beby S.; Afiati, .; Hassan, Abdul H.; Hernowo, Bethy S.
Journal of Medicine and Health Vol 1, No 1 (2015)
Publisher : Maranatha Christian University

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Abstract

Nasopharyngeal carcinoma (NPC) is an epithelial malignancy originating from the surface of the lateral and posterior wall of the nasopharynx. Bcl-2 is an oncoprotein that plays an important role in disrupting the process of apoptosis. Expression of Bcl-2 in biopsy samples of undifferentiated NPC also related to the nature of more aggressive tumor mass and unfavorable clinical radiotherapy response. The purpose of this study was to assess the relationship of Bcl-2 expression with radiotherapy response in undifferentiated NPC. The method of this study areusing 40 samples of paraffin blocks were diagnosed as undifferentiated NPC by histopathologic examination with H&E staining. The samples were divided into 2 groups who respond and do not respond to radiotherapy. All samples examined by Bcl-2 immunohistochemistry and the expression willanalyzed and assess therelationship to radiotherapy response. Of the 40 cases of undifferentiated NPC show imunoekspresi Bcl-2 positive in 39 cases (97.5%) and 1 case (2.5%) negative from response group. The results of statistical analysis of the Bcl-2 obtained significant results with p value <0.05 so we can conclude there is a relationship between Bcl-2 expression with radiotherapy response. Conclusion, Bcl-2 can be used as a predictor for the success of radiotherapy in undifferentiated NPC. Keywords: Bcl-2, undifferentiated NPC, radiotherapy response

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