cover
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kab. magelang,
Jawa tengah
INDONESIA
Jurnal Farmasi Sains dan Praktis
ISSN : 25499068     EISSN : 25794558     DOI : -
Core Subject : Health, Science,
Jurnal Farmasi Sains dan Praktis is a scientific journal published by the University Muhammadiyah Magelang. Jurnal Farmasi Sains dan Praktis published two times a year, namely in April and October since 2014 with p-ISSN 2549-9068 and e-ISSN 2579-4558, open access, peer-reviewed. The article published in the Jurnal Farmasi Sains dan Praktis should not be published in other journals or have been previously published. Jurnal Farmasi Sains dan Praktis aims to serve the updated scientific knowledge for international researchers in pharmaceutical sciences. Jurnal Farmasi Sains dan Praktis accepts review articles, original research articles.
Arjuna Subject : -
Articles 108 Documents
GAMBARAN PENGGUNAAN OBAT DAN TINGKAT KONTROL ASMA PADA PASIEN ASMA DEWASA RAWAT JALAN DI BKPM MAGELANG PERIODE FEBUARI-MARET 2016 astuti, whiliani indra; Hapsari, Widarika; Lutfiyati, Heni
Jurnal Farmasi Sains dan Praktis Vol 4 No 1 (2018)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v4i1.2588

Abstract

Asma merupakan penyakit inflamasi kronik saluran pernapasan. Saat ini diperkirakan sekitar 100-150 juta penduduk di dunia menderita asma, jumlah ini diperkirakan akan terus bertambah hingga mencapai 180.000 orang setiap tahunnya. Tingginya prevalensi asma yang terjadi, maka dibutuhkan perhatian khusus dalam penggunaan obat untuk meningkatkan tingkat kontrol asma pada pasien asma. Penelitian ini bertujuan untuk mengetahui penggunaan obat dan tingkat kontrol asma pada pasien asma rawat jalan di Balai Kesehatan Paru Masyarakat Magelang.Penelitian ini merupakan penelitian deskriptif, pengambilan data dilakukan dengan resep pasien asma secara prospektif dan dilakukan pendekatan non eksperimental dengan pengamatan secara tidak langsung menggunakan kuesioner ACT untuk mengetahui tingkat kontrol asma. Sampel dalam penelitian ini berjumlah 46 responden, pengambilan sampel menggunakan tehnik purposive sampling. Hasil penelitian disajikan dalam bentuk tabel disertai pembahasan. Pasien asma yang paling banyak yaitu perempuan berjumlah 30 orang (65%), sedangkan laki-laki berjumlah 16 orang (35%). Distribusi pasien asma terbanyak pada kelompok umur 42-47 tahun (24%) dan umur 48-53 tahun (20%). jenis obat yang banyak digunakan di BKPM Magelang untuk pengobatan asma yaitu obat agonis β2 adrenergik (47,41%). Pasien asma yang tidak terkontrol sebanyak 24 orang (52%), dan yang terkontrol sebagian sebanyak 22 orang (48%).
PERBANDINGAN MUTU FISIK TABLET AMBROXOL MEREK DAGANG X DANTABLETMBROXOL GENERIK friski, oktavia; Pribadi, Prasojo; Hidayat, Imron
Jurnal Farmasi Sains dan Praktis Vol 4 No 1 (2018)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v4i1.2587

Abstract

Ambroxol adalah salah satu obat yang masuk kedalam golongan mukolitik. Dimana tujuan dari penelitian ini adalah mengetahui perbandingan mutu fisik tablet Ambroxol merek dagang dan tablet Ambroxol generik. Metode penelitian yang dilakukan adalah eksperimental yang dilakukan di Laboratorium DIII Farmasi Universitas Muhammadiyah Magelang. Data yang dihasilkan disajikan dalam bentuk tabel dan grafik, kemudian data dibandingkan dengan standar persyaratan Farmakope Indonesia edisi III dan IV dan kepustakaan lain. Dilakukan uji statistik Kolmogorov-Sminorv, dilanjutkan uji One Way Anova dengan taraf kepercayaan 95%. Hasil penelitian menunjukkan tablet Ambroxol merek dagang X memenuhi persyaratan yang telah ditetapkan, untuk tablet Ambroxol generik mengenai keseragaman ukuran dan kekerasan tablet Ambroxol generik tidak memenuhi persyaratan. Berdasarkan hasil uji statistik didapatkan hasil yaitu ada perbedaan yang signifikan antara Tablet Ambroxol merek dagang X dan tablet Ambroxol generik, kecuali dalam hal kerapuhan tablet.
GAMBARAN TINGKAT PENGETAHUAN DAN KETEPATAN PENGGUNAAN INHALER PADA PASIEN ASMA RAWAT JALAN DI RSUD TIDAR KOTA MAGELANG PERIODE FEBRUARI 2016 prastika, dianita; Lutfiyati, Heni; Dianita, Puspita
Jurnal Farmasi Sains dan Praktis Vol 4 No 1 (2018)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v4i1.2586

Abstract

Asma merupakan penyakit kronis saluran pernafasan yang ditandai oleh inflamasi, peningkatan reaktivitas terhadap berbagai stimulus dan sumbatan saluran nafas yang tidak bisa spontan atau dengan pengobatan yang sesuai. Tujuan dari penelitian ini adalah untuk mengetahui tingkat pengetahuan dan ketepatan penggunaan inhaler pada pasien rawat jalan di RSUD Tidar Kota Magelang. Desain penelitian ini adalah deskriptif dengan pendekatan kuantitatif. Metode pengambilan sampel dengan purposive sampling. Data dikumpulkan dari 35 responden melalui pengisian kuesioner pada bulan Februari 2016. Instrument yang digunakan berupa kuesioner. Dilakukan pada sampel sebanyak 35 responden pada pasien rawat jalan di RSUD Tidar Kota Magelang. Data yang diperoleh diolah dengan program Microsoft Excel dan di analisis berdasarkan persentase jawaban responden. Hasil karakteristik responden berdasarkan usia responden berusia 56 – 65 tahun(46%), berdasarkan jenis kelamin adalah yaitu laki –laki 14 responden (40%) dan perempuan 21 responden (60%), berdasarkan frekuensi kedatangan mayoritas sudah lebih dari 5 kali (57%), berdasarkan hasil penelitian dapat disimpulkan bahwa tingkat pengetahuan pasien terhadap penyakit asma 20 responden (57 %) dinyatakan memiliki pengetahuan yang baik dan 27 responden (77%) sudah tepat dalam menggunakan inhaler jenis Matered Dose Inhaler (MDI). Kata Kunci: pasien asma; tingkat pengetahuan; ketepatan penggunan inhaler.
GAMBARAN TINGKAT KEPUASAN PASIEN UMUM RAWAT JALAN TERHADAP KUALITAS PELAYANAN INFORMASI OBAT DI INSTALASI FARMASI BALAI KESEHATAN PARU MASYARAKAT (BKPM) MAGELANG PERIODE FEBRUARI 2016 Fatmawati, Afif Tia; Yuliastuti, Fitriana; Hapsari, Widarika Santi
Jurnal Farmasi Sains dan Praktis Vol 4 No 1 (2018)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v4i1.2585

Abstract

Kepuasan pasien adalah suatu tingkat perasaan pasien yang timbul sebagai akibat dari kinerja layanan kesehatan yang diperoleh setelah pasien  membandingkannya  dengan apa yang diharapkan. Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pasien umum rawat jalan terhadap kualitas pelayanan informasi obat di instalasi farmasi Balai Kesehatan Paru Masyarakat (BKPM) Magelang periode Februari 2016.Penelitian ini menggunakan metode deskriptif dengan pendekatan kuantitatif. Metode pengambilan sampel dengan Purposive Sampling. Data dikumpulkan dari 50 responden melalui pengisian kuesioner pada bulan Februari 2016.Variabel yang digunakan dalam penelitian ini adalah kehandalan, ketanggapan, keyakinan, empati, dan fasilitas berwujud. Data yang diperoleh diolah dengan program Microsoft Excel dan dianalisis dengan membandingkan persepsi kenyataan dengan harapan yang digambarkan dalam Diagram Kartesius. Berdasarkan dari hasil penelitian mayoritas responden berjenis kelamin perempuan sebesar 54%, berdasarkan usia yang terbanyak 21 – 35 tahun dengan persentase sebesar 46%, berdasarkan pendidikan terakhir mayoritas perguruan tinggi/ akademi sebesar  46%, sedangkan berdasarkan pekerjaannya mayoritas bekerja pegawai negeri sipil  dengan persentase sebesar 30%, kemudian mayoritas rata – rata penghasilan lebih dari Rp 3.000.000,00 dengan persentase sebesar 56%, hubungan dengan pasien mayoritas untuk diri sendiri dengan persentase sebesar 66% dan frekuensi kedatangan ke apotek mayoritas lebih dari 5 kali sebesar 64%. Berdasarkan data tersebut dapat disimpulkan bahwa terdapat pengaruh variabel independen yaitu kualitas pelayanan meliputi kehandalan, ketanggapan, keyakinan, empati, dan fasilitas berwujud terhadap variabel dependen yaitu kepuasan pasien.Pasien merasa puas dengan pelayanan informasi obat di Instalasi farmasi Balai Kesehatan Paru Masyarakat (BKPM) Magelang.
DETERMINATION OF TOTAL FLAVONOID LEVELS OF RIDGE GOURD FRUIT WITH UV-VIS SPECTRUMFOTOMETRY METHOD Estikawati, Indriani; Lindawati, Novena Yety
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.2684

Abstract

Ridge gourd fruit (Luffa acutangula (L.) Roxb.) is one kind of tuber plants that grows in many tropical and various kinds. Ridge gourd fruit are widely consumed by the people of Indonesia. Chemical content of ridge gourd fruit such as flavonoids has the potential as antidiabetic. The purpose of this study is to determine the total flavonoid levels found in ridge gourd fruit by uv-vis spectropotometric method. Ridge gourd fruit extracted with metanol:cloroform (4:1) mixture by maceration method. Analysis qualitative of flavonoid content were carried out with Wilstater, Smith Metacalfe, and Thin Layer Kromatgrafi (TLC). Quantitative analysis of total flavonoids using UV-Vis spectrophotometric method at wavelength 413,2 nm with complex forming reactions AlCl3. The results of qualitative tests show that ridge gourd fruit contain flavonoids positive. The average level of total flavonoids of ridge gourd fruit is 10,08 and the coeficient of variation (CV) with the result of 0,69%  
WULUH STARFRUIT (AVERRHOA BILIMBI) EXTRACT GEL FOR RECURRENT AFTOSA STOMATITIS Nakhil, Umaimatun; Sikumbang, Isabella Meliawati; Putri, Nugrahani Hendra; Lutfiyati, Heni
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.2713

Abstract

The purpose of this study was to test the antibacterial activity of the gel extract of Wuluh starfruit (Averrhoa bilimbi L.).  So that it can provide a representation of the use of starfruit in medicine and as an enrichment of insight.  Averrhoa bilimbi L contains flavonoids, tannins and saponins which have antibacterial properties.  The stages that have been carried out include identification and determination of the starfruit fruit plant, then the simplicia powder of starfruit is extracted using 70% ethanol by maceration which is then carried out evaporation on the waterbath to obtain thick extract.  Then made the gel preparation with a concentration of b / v 40%, 45% and 50%. Evaluation of stability physical gel includes organoleptic test, homogeneity, pH, viscosity and spreading ability. The result showed that the three formulas were thick, brown with a characteristics smell of starfruit, homogeny, pH 5, viscosity 190-260 dPas and the spreadability test was 2,5-4,2 cm.   Then a bacterial suspension was made by being immersed for 24 hours at 37 ?.  Then tested by dividing into 5 treatment groups, with positive controls Amoxicillin and negative control gel basis.  The results showed that the average inhibition zone for each treatment was positive control 4.66 cm, negative control 0 cm, gel 40% 1.77 cm, gel 45% 1.93 cm, and gel 50% 2.67 cm.  From the average inhibitory zone it can be seen that gel wuluh starfruit extract has antibacterial activity.    
THE COMBINED EFFECT OF EXTRACT OF TAMARINDUS INDICA L. LEAVES AND ANNONA MURICATA L. LEAVES ON BLOOD GLUCOSE LEVELS IN MALE RATS WISTAR STRAIN INDUCED ALLOXAN Kusuma, Eka Wisnu; Safarini, Eka; Anggraini, Devina Ingrid
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.2952

Abstract

A recent study States that the leaves of the tamarind and soursop can lower blood glucose levels with a single dose. This research was conducted to find out the influence of the combination of ethanol extracts of leaves of the tamarind and soursop leaf in mice induced aloksan. Test treatment consists of 8 groups, normal, negative control (aloksan), positive (glibenklamid), the dose I (tamarind), dose II (soursop), AJ III dosage: SIR 25:75 dose), IV (AJ: SIR 50:50), dosage V (AJ: SIR 75:25). All groups (except normal) induced with aloksan 160 mg/KgBB. Then proceed with a test of treatment of each group of the drug start day 0 up to 14 in per-oral. The taking of blood glucose levels is done on the day 0, 7 and 14. Administering ethanol extracts of leaves of tamarind and soursop both single and combination capable of lowering blood glucose levels seen from the average hypoglycemic
ANALYSIS OF DRUG INDICATOR AT THE PROCUREMENT STAGE IN THE NATIONAL HEALTH INSURANCE ERA: A STUDY IN ADVANCE HEALTH FACILITY Sulistyaningrum, Indriyati Hadi; Santoso, Arifin; Lestari, Sri Intan; Arbianti, Kusuma
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.2964

Abstract

Drug procurement is part of an important hospital management to support the availability of the pharmaceutical logistic in hospital to provide good services for the patients. ineffective procurement can result in not achieving the availability of each drug in the amount which are in accordance with the price and budgeting. This research was conducted to obtain an overview of drug management at the procurement stage in Sultan Agung Islamic Hospital (RSIA SA) for the 2017 ? 2018 period.  Descriptive Observational research methods were used to collect the qualitative and quantitative data. Qualitative data were obtained through interview, and the quantitative data were collected from the document observation provided in Pharmaceutical installation Sultan Agung Islamic Hospital (IFRSISA). The result showed the percentage of the allocation of drug procurement funds in 2017 was 47,6%, and in 2018 it was 37,1%, the frequency of procurement of each drug type was < 76% at 12 times / year, the frequency of delayed payment by the hospital based on the time agreed was 100%. The conclusion of this study shows that the indicator of drug procurement in IFRSISA categorized as good because it is in line with the quality of drug procurement indicators.   
ANTIBACTERIAL ACTIVITY OF ACETONE AND ETHYL ACETATE LEAVES, STEMS AND RHIZOMES EXTRACT OF WHITE WATER LILY (NYMPHAEAE ALBA) AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI Ulfah, Mariam; Irawan, Ade; Putra, Teguh Adiyas
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.2999

Abstract

White water lily (Nymphaeae alba) is one of the aquatic plants that is often used for traditional medicine. This plant has anticancer and antioxidant activity. The final result of this experiment is to determine the antibacterial activity of acetone and ethyl acetate extract from several parts of this plant, including leaves, stems and rhizomes againts  several types of bacterial including Staphylococcus aureus and Escherichia coli.  Kirby-Bauer diffusion Disc method is used in this study. Simplicia of leaves, stems and  rhizomes of white water lily were macerated with acetone and ethyl acetate for 3 x 24 hours. Antibacterial tests were carried out to acetone and ethyl acetate leaves, stems and rhizome extract of white water lily.  Amoxicillin was used  as a positive control and dimethyl sulfoxide (DMSO) with concentration 20% as a negative control. The extract and amoxicillin were diluted with 20% DMSO. Each disk contained 100 µg of extract and 10 µg of amoxicillin. Antibacterial tests that have been carried out show that the acetone extract of leaves, stems and rhizomes white water lily has the highest attack value against bacteria, the diameter of the inhibition zone is 20 mm against S. aureus Acetone and ethyl acetate leaves, stems and rhizomes extract of white water lily did not have inhibitory effect on E. coli.  
ANTHELMINTIC POTENTIAL OF MORINGA OLEIFERA AS INHIBITOR MITOCHONDRIAL RHODOQUINOL-FUMARATE REDUCTASE FROM ASCARIS SUUM USING THE DOCKING METHOD Novian, Dede Rival
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.3000

Abstract

One of the parasitic nematodes that can cause malnutrition, even death in humans, is Ascaris suum. The parasite can survive in its host cell by metabolizing using the fumarate reductase enzyme. With this metabolism, the parasite can produce energy to survive in its host cell. Rhodoquinone (RQ) plays a part in helping the fumarate reductase reaction in parasite metabolism, and energy from metabolism was not produced when the enzyme was disrupted. Thus Mitochondrial rhodoquinol-fumarate reductase can be a good target of anthelmintic drug receptors. The results of investigations using in vitro and in vivo methods showed that Moringa oleifera has various medicinal functions including anti-inflammatory, antimicrobial, antidiabetic, antioxidant, anti-tumour, anti-cancer, and anti-clastogenic properties. However, the potential of the drug Moringa oleifera against anthelmintics has not been further investigated. Simulation docking is the research method used to find the anthelmintic potential of Moringa oleifera as the Ascaris suum inhibitor of Mitochondrial rhodoquinol-fumarate reductase. This study aims to examine the potency of Moringa oleifera bioactive compounds on the anthelmintic receptor Mitochondrial rhodoquinol-fumarate reductase by using efficient and effective research time with the docking simulation model. The results showed the bioactive compound 3,5-bis (1,1-dimethylethyl) -phenol from Moringa oleifera had potential as a new anthelmintic drug compound, 3,5-bis (1,1-dimethylethyl) -phenol activity had affinity energy of - 7.0 kcal / mol and has physicochemical properties that are not contrary to the rules of the drug compounds from Lipinski.

Page 1 of 11 | Total Record : 108