cover
Contact Name
Lukas Widhiyanto, dr., SpOT(K)
Contact Email
joints@fk.unair.ac.id
Phone
(+6231) 5501481
Journal Mail Official
joints@fk.unair.ac.id
Editorial Address
Jl. Prof. Dr. Moestopo 6-8, Surabaya
Location
Kota surabaya,
Jawa timur
INDONESIA
(JOINTS) Journal Orthopaedi and Traumatology Surabaya
Published by Universitas Airlangga
ISSN : -     EISSN : 24608742     DOI : 10.20473/joints.v8i2.2019.59-67
Core Subject : Health, Engineering,
The JOINTS research topics are relating to education and training in the field of orthopedics and traumatology, including research reports, case reports, and literature reviews.
Articles 37 Documents
THE EFFECT OF DECELLULARIZATION TECHNIQUE ON COLLAGEN TYPE II AND MATRICES POROSITY OF CARTILAGE BOVINE SCAFFOLD Utomo, Dwikora Novembri; Sari, Ika Benny Kartika
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 7, No 1 (2018): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (851.371 KB) | DOI: 10.20473/joints.v7i1.2018.42-54

Abstract

Background: Cartilage has limited capacity for self-repair in case of defect. Stem cell based tissue engineering has become an alternative therapy for the treatment of cartilage defect. The use of decellularized cartilage bovine can serve as scaffold to support proliferation dan differentiation of the stem cell.Purpose: This research is to compare the effect of decellularization technique on collagen type II and matrices porosity of cartilage bovine scaffold.Methods: This experimental laboratory research used cartilage bovine scaffold which was decellularized using physical, chemical and enzymatic techniques with different time and concentration variations, then collagen type II measurement was performed by immunohistochemical method and evaluation of porosity size with electron microscopy.Results: In the preparations with the highest concentration and the longest immersion time of 5% SDS for 72 hours, the decellularization process occurs perfectly. The collagen type II content was found to have significantly higher concentrations than the controls and other preparations, and have interconnected porosities in large size.Conclusion: High concentrations of collagen type II  and large diameter of pores after decellularization process in cartilage bovine scaffold confirm that this scaffold still has optimum biochemical cues that can be a good mechanical framework and microenvironment stem cell in effort to repair the cartilage defects. This result was expected to become a standard for the decellularization making of cartilage bovine scaffold.
EFFECT OF PLATELET RICH FIBRIN AND MESENCHYMAL STEM CELL ON MYOBLAST AND FIBROBLASTS RATIO IN RABBIT MUSCLE DEFECT Utomo, Dwikora Novembri; Chilmi, Mohammad Zaim; Fiandana, Angga
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 7, No 2 (2018): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1243.858 KB) | DOI: 10.20473/joints.v7i2.2018.95-105

Abstract

Background: One of the problems in Orthopedics which often results in less satisfactory outcomes is the muscle injuries treatment. This is due to slow healing process and outcome has not been optimal because it produces scar tissue.Purpose: To evaluate effect of platelet rich fibrin and allogenic mesenchymal stem cell on muscle regeneration through comparation of myoblast and fibroblast ratio.Methods: This research is true experimental with randomized pre and post test with control group design. The treatment group included administering allogenic mesenchymal stem cells (MSC), rich fibrin platelets (PRF), and a combination of both. The study subjects were New Zealand White Rabbit which gastrocnemius muscle is incised. Muscle quality evaluation was done in the second and fourth weeks through histology examination in the form of myoblast cell ratio to fibroblast.Results: In the second week evaluation, administering allogenic MSC combined with PRF gave significant results to an increase in myoblast cell ratio to fibroblast. While evaluation of fourth week, giving of three treatment groups gave significant result to myoblast cell ratio to fibroblast.Conclusion: Allogenic MSC administration combined with PRF can improve New Zealand White Rabbit muscle healing quality by histological examination.
MODIFIED LAUTENBACH TECHNIQUE AND EXTERNAL FIXATION AS A TREATMENT FOR INFECTED NON-UNION OF THE SUBTROCHANTER FEMUR: A CASE REPORT Edward, Mouli; Wardhana, Teddy Heri; Nasrullah, Erfan
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 8, No 1 (2019): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (931.849 KB) | DOI: 10.20473/joints.v8i1.2019.25-34

Abstract

Infected non-union is still a challenging orthopedic case to treat. Up until present day, there is no any established protocol to treat infected non-union of femur. Infection at subtrochanter femur specifically poses extra challenge as aforementioned location is affected by great tension and compression force. In this report, we present a 20-yo woman with infected subtrochanter femur following open reduction internal fixation (ORIF)with angle blade plate (ABP) 95o. One stage surgery was performed involving implant removal, debridement, definite external fixation, and antibiotic delivery using modified Lautenbach technique. Four years after trauma, the patient was capable of independent mobilization without aid. No infection recurrence was found, and Haris Hip Score was 91 (excellent). Based on the result of this case, definite external fixation and modified Lautenbach technique in one stage surgery can be a viable option in treating infected non-union of subtrochanter femur.
CLINICAL EVALUATION OF POST TOTAL HIP / KNEE REPLACEMENT IN HIP / KNEE SPINE SYNDROME Fachrizal, Achmad; Irianto, Komang Agung
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 6, No 1 (2017): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (468.88 KB) | DOI: 10.20473/joints.v6i1.2017.40-47

Abstract

Insiden osteoarthritis pada hip joint, osteoarthritis pada knee joint, dan degenerative lumbar spondylosis semakin meningkat seiring dengan bertambahnya populasi penduduk usia tua. Kasus Hip/Knee Spine syndrome sendiri cukup sering ditemukan. Namun literatur yang mengevaluasi kondisi klinis, khususnya keluhan low back pain pada pasien dengan hip/knee spine syndrome post total hip/knee replacement masih sangat terbatas Tujuan dari penelitian ini adalah untuk mengevaluasi efek dari total hip/knee replacement pada pasien dengan hip/knee spine syndrome, berkaitan dengan keluhan low back pain.Penelitian ini adalah observasional retrospektif. Penelitian ini menggunakan 5 orang pasien post total hip/knee replacement yang juga didapatkan keluhan low back pain. Pasien yang terpilih akan dievaluasi klinis dengan menggunakan kuesioner LBP VAS Score, Oswestry Disability Index, Hip Harris Score untuk pasien post total hip replacement, dan Oxford Knee Score untuk pasien post total knee replacement. Dilakukan pengamatan pre dan post operasi pada seluruh pasien. Data pasien didapatkan dari Rumah Sakit Orthopaedi dan Traumatologi Surabaya mulai bulan Juni-November 2015.Berdasarkan test paired samples, didapatkan hasil sig 0,001 (< 0,05) pada skor VAS dan sig 0,033 (<0,05) pada skor ODI. Maka dapat disimpulkan bahwa terdapat perbedaan yang signifikan antara skor VAS LBP dan skor ODI sebelum dan setelah terapi Hip/Knee Replacement pada pasien dengan Hip/Knee Spine Syndrome.
BLOUNT DISEASE EVALUATION OF THE OPERATIVE TREATMENT WITHIN 2006-2014 IN DR. SOETOMO GENERAL HOSPITAL SURABAYA Suryaningrat, Komang Agung Irianto; M. Ranuh, I. G. Ng. Dodo
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 6, No 2 (2017): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (692.783 KB) | DOI: 10.20473/joints.v6i2.2017.55-62

Abstract

Background: Blount disease is a growth disturbance of the medial side of the proximal physeal of the tibia, epiphyseal and metaphyseal. Clinically this disease marked by varus angulation and internal rotation of the tibia on the metaphyseal area below knee.Method: This paper evaluating 2 cases of blount disease treated surgically in Soetomo general hospital within 2006 ? 2014. The evaluation based on MDA (meta-diaphyseal angle) pre and post operatively.Result: Showed significant and satisfactory to patients and parents who have carried out the operation. A reduction in the angle of MDA, in first patients the MDA angle before surgery was 18 degrees on the right 40 degrees on the left, after surgery MDA was 24 degrees on the right, 10 degrees on the left. The second patient MDA before surgery was 32 degrees on the right and 33 degrees on the left, after the surgery MDA was 12 degrees on the left side, for the right side hasn?t operated yet.Discussion and Conclusion: There is hope for correction on severe form of blount disease. Correction by performing a proximal tibia osteotomy on the affected bone.
LOWER LEG DEFORMITY CORRECTION USING ILIZAROV DEVICE IN DR SOETOMO GENERAL HOSPITAL SURABAYA: A CASE SERIES Andrianus, Jeffry; Prasetya, Citra Ahdi
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 7, No 1 (2018): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (998.248 KB) | DOI: 10.20473/joints.v7i1.2018.85-94

Abstract

Background: limb deformity, especially lower leg deformity is a common case in orthopaedic practice. Limb deformity can be classified according to cause (Congenital, developmental, post trauma), geometry (angulation, rotation, shortening), severity and progression. In severe and complex deformity, the treatment choice is gradual correction using Ilizarov system. Benefit of the gradual correction using Ilizarov system are: (1) reduce the risk of neurovascular injury, (2) minimal soft tissue disturbance, (3) multiplanar and multidirectional correction.Cases: We have performed 11 deformity correction using ilizarov device during january 2013- September 2017. Evaluation data was obtained retrospectively from medical record. Nine patients were managed by Ilizarov device for bone lengthening indication and 2 patients for bone transport indication. The treatment result was evaluated using ASAMI scoring system for bone condition and functional condition.Results: Elevent patients were managed by Ilizarov system for gradual deformity correction. Nine patients already finished the treatment and the frame was removed. We cannot evaluate two patients because the correction was not finished. The ilizarov device was changed with other fixation because implant failure during correction phase. Evaluation using ASAMI score showed good bone score result for 9 patients and 7 excellent results for functional score.Conclusion: Ilizarov system has a promising result to correct lower limb deformity patients in Dr Soetomo General Hospital.
QUALITY OF LIFE COMPARATION IN METASTATIC BONE DISEASE PATIENT BEFORE AND AFTER SURGERY IN DR. SOETOMO GENERAL HOSPITAL Mahyudin, Ferdiansyah; Edward, Mouli; Basuki, Muhammad Hardian; Satria, Rizky Agung
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 7, No 2 (2018): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (744.583 KB) | DOI: 10.20473/joints.v7i2.2018.132-138

Abstract

Background: Metastatic bone disease is bone pathologic process caused by spread of primary tumor. The incidence of metastatic bone disease varies between 20-75% corresponds to the primary site of the malignancy. Surgery in metastatic bone disease aim to cure or palliate the morbidity caused by the disease. Operative treatment could reduce pain, improve function, control metastatic focus of the malignancy, and provide mechanical stabilization. Based on those benefits, operative treatment is important to improve quality of life in patients with metastatic bone disease. Purpose:  Proved that there was a difference in the quality of life MBD patients before and after surgery.Methods: This research was a retrospective cohort on MBD patients which undergone surgery, and never given any other treatment in the course of the disease. The research was conducted in Dr. Soetomo General Hospital, Surabaya. Patient sampling was done using consecutive sampling. Karnofsky score was taken from the medical record before the procedure and direct interview via phone or completing questionnaire. Data analysis was done descriptively and analytically. Statistical tests were done using Wilcoxon test.Results: 146 patients enrolled in the research. The mean age of the sample was 48.77 ± 13.34 years. The mean of Karnofsky score before and after the procedure was 53.69±13.07 and 75.54±13.69 with statistical result of p<0.001.Conclusion: The Karnofsky score in MBD patients was higher after the surgery compared to before the surgery.
LEVEL OF PROCALCITONIN PLASMA AS AN EARLY SEPSIS BIOMARKER IN POLYTRAUMA PATIENTS IN DR HASAN SADIKIN GENERAL HOSPITAL BANDUNG Wibowo, Ricky; Rasyid, Hermawan Nagar; Ismono, Darmadji
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 8, No 2 (2019): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (773.636 KB) | DOI: 10.20473/joints.v8i2.2019.68-76

Abstract

Background: Polytrauma patients have a risk of progressive organ dysfunction due to uncontrolled immunological process. Sepsis and multiple organ failure are the most common causes of morbidity and mortality in late death of polytrauma patients. Clinical diagnosis and routine laboratory test are not specific until the patient entered a critical state. Delayed diagnosis of sepsis is caused by difficulties in diagnosing. Procalcitonin is a biomarker that is useful in predicting the onset of sepsis. The aim of this research is to determine the level of procalcitonin as early biomarker sepsis in polytrauma patients in RSHS Bandung. Methods: A diagnostic study using secondary data from the Academic Leadership Grant (ALG) study on polytrauma patients in Emergency Room of RSHS Bandung from January-June 2017. This study determined the cut of point, sensitivity, spesificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV), and accuracy to diagnosis sepsis.Result: A total of 70 subjects were enrolled in this study, 92.9% were male gender with average age 33.21±13.395 years old. Twenty-one patients (30%) were diagnosed with sepsis. Based on receiver operating characteristic (ROC) curve showed the level of procalcitonin was given in the area under curve (AUC) 0.96 with Confidence Interval 0.923-1.00 (p < 0.05). The Procalcitonin cut of point was 1.46 ng/mL with a sensitivity of 90.5%, specificity of 89.8%, PPV of 79.2%, NPV of 95.7%, and accuracy of 90.0%.Conclusion: Plasma Procalcitonin 1.46 ng/mL is a good predictor for early diagnosis sepsis toward polytrauma patients.
THE ROLE OF PLATELET-RICH FIBRIN FACILITATES THE HEALING OF GASTROCNEMIUS MUSCLE DEFECT: A PRELIMINARY STUDY ON ANIMAL MODEL Utomo, Dwikora Novembri; Hernugrahanto, Kukuh Dwiputra
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 7, No 1 (2018): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (797.109 KB) | DOI: 10.20473/joints.v7i1.2018.31-41

Abstract

Background: Scar formation has been a classical issue in the healing of skeletal muscle defect which will results in decrease of strength and function. Platelet-rich plasma (PRP) has been studied to enhance the healing of muscle defect. The disadvantages of it include the risk of immunologic reaction, time-consuming preparation, and lack of scaffold element. Platelet-rich fibrin (PRF) is a new generation of platelet concentrate that provides good source of growth factors and scaffold element necessary for the healing. This study is to provide a fondation of PRF preparation and implantation for the healing of experimental defect of gastrocnemius muscle in an animal model.Purpose: The goal is to provide a fondation of PRF preparation and implantation for the healing of experimental defect of gastrocnemius muscle in an animal model.Methods: Animal Care and Use Committee, Airlangga University approved the study. Twenty New Zealand white rabbits were divided into two groups. In control group, a defect was created in the right gastrocnemius and no implantation was done. In study group, similar defect was created with implantation of PRF. Two and four weeks after surgery, the defect was examined immunohistochemically for the expression of Pax7 protein.Results: The implanted group showed higher IRS score in two and four weeks compared to the control group.Conclusion: The use of PRF facilitates the healing of muscle injury. This study will be used as a fondation for further study on PRF.
THE EFFECT OF PLATELET RICH PLASMA ON MESENCHYMAL STEM CELLS (MSCS) DIFFERENTIATION INTO CHONDROBLAST Utomo, Dwikora Novembri; Widiastana, I Gde Adi
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol 6, No 2 (2017): JOINTS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1025.76 KB) | DOI: 10.20473/joints.v6i2.2017.80-85

Abstract

The addition of platelet rich plasma to mesenchymal stem cell culture on growth  media and  chondrogenic  media  had  any effect  on stem cell?s proliferation and differentiation into chondroblast has not been determined. This research is to find  out  the  effect  of  platelet  rich  plasma  on  mesenchymal  stem  cell?s differentiation and proliferation into chondroblast on in vitro media. Randomized control group posttest only design. Blood was taken from the rabbit?s vein to be processed into platelet rich plasma (PRP). Mesenchymal Stem Cell (MSC) was harvested from the bone marrow of the rabbit to be cultured. The MSC?s culture were divided into three groups of modification. The first group was combination of MSC added with Complete Culture Medium (CCM) and Chondrogenic Diferentation Medium (CDM) without PRP as control group. The second group had the same combination as the first group with extra 5% PRP. The third group had the same combination as the first group with extra 10% PRP. The results were evaluated in the following 21 days. The group that received extra 5% PRP had significant increase of chondroblast count compared to the group without PRP addition (p=0,033). The same result also occured on the groups that received extra 10% PRP compared to the group without PRP addition (p=0,028). There were no significant diferences between both the second and the third groupchondroblast count (p=0,203). There was a significant effect of platelet rich plasma on mesenchymal stem cell?s diferentiation and proliferation into chondroblast on invitro media.

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