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Contact Name
Ilhami Romus
Contact Email
ilhamiromus@yahoo.co.id
Phone
+6281371333123
Journal Mail Official
jikfkunri@gmail.com
Editorial Address
Sekretariat JIK (Jurnal Ilmu Kedokteran) Jl. diponegoro no. 1, Pekanbaru Riau
Location
Kota pekanbaru,
Riau
INDONESIA
Jurnal Ilmu Kedokteran
Published by Universitas Riau
ISSN : 1978662X     EISSN : 27154467     DOI : https://doi.org/10.26891/JIK
Core Subject : Health, Science,
Journal of Medical Science receives a script from health and medical lecturer, undergraduate, residents, hospital staff and those who interested in writing scientific papers. The scientific articles posted on JIK include: literature reviews, research article, case report and EBCR (Evidence Based Case Report). Article preferably basic science of medicine and health.
Articles 10 Documents
Search results for , issue "Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran" : 10 Documents clear
Relative Expression of Soluble tnf Versus Transmembrane tnf in Spondyloarthritis Masdar, Huriatul
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.452 KB) | DOI: 10.26891/JIK.v4i1.2010.56-64

Abstract

TNF is important in rheumatoid arthritis (RA) and spondyloarthritis (SpA) pathogenesis. Recently reports showedsTNF levels were significantly lower in SpA than RA synovial fluid (SF). Therefore, the differential regulation of TNFin both diseases were investigated focusing on the balance of sTNF-tmTNF and both TNF receptors expression. Synovialfluid from 22 RA and 25 SpA were analyzed by ELISA. sTNF was confirmed significantly higher in RA than SpA.Total TNF of synovial tissues assessed by qPCR showed similar levels, suggesting a higher tmTNF/sTNF ratio in SpA.The levels of sTNF-R1 and sTNF-R2 were significantly lower in SpA than RA SF. Interestingly, sTNF-R2/sTNF-R1increased in SpA. qPCR on synovial tissue showed similar mRNA levels for TNF-R2 but decrease of TNF-R1 in SpA.IL-6R levels did not showed differences and TIMP-3 tended to be higher in RA than in SpA SF. In conclusion, weobserved a shift from sTNF/TNF-R1 in RA to tmTNF/TNF-R2 in SpA.
Infestasi Cacing Usus dan Faktor-Faktor yang Mempengaruhinya pada Anak yang Tinggal di Daerah Aliran Sungai Siak Kelurahan Pesisir Kecamatan Lima Puluh Pekanbaru Yolazenia, Yolazenia; Lesmana, Suri Dwi; Haslinda, Lilly
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (46.402 KB) | DOI: 10.26891/JIK.v4i1.2010.14-19

Abstract

Children living around river have higher risk to get helminthes infection. The aim of this study was to determine theprevalence and intensity of helminthes infection and its risk factors for children living around Siak River in KelurahanPesisir, Kecamatan Limapuluh, Pekanbaru. A cross-sectional study conducted in September to November 2008, and 65children participated. Stool were examined using the Kato-Katz technique and the intensity of infections was categorizedinto: light, moderate, or heavy. The parent of children was asked to fill the questionnaire. We found that 36,9%subjects were infected by intestinal helminthes. The most common infection was A.lumbricoides and T.trichiura. Mostof the subjects had light intensity of infection. There were no correlations between the habits of using river as: sourceof drinking water, place to defecate, place to take a bath and brush teeth, place to wash vegetables and kitchen tools,and the flood with helminthes infection.
Efek Air Perasan Umbi Bawang Merah (Allium ascalonicum L.) terhadap Profil Lipid Plasma Mencit (Mus musculus) Ismawati, Ismawati; Wahyuni, Sri; Wirna, Nora
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (40.858 KB) | DOI: 10.26891/JIK.v4i1.2010.48-55

Abstract

One of atherosclerosis risk factor is dislipidemia. One of plant that is expected to overcome dislipidemia is shallot(Allium ascalonicum L.). The aim of this research was to know the effect of shallot’s extraction water on the plasmalipid profile of mice. Groups with treatment consist of yolks group, and shallot water extraction divided into threetreatmen level ; 20%, 40% and 80%. Parameters that were measured were total cholesterol level, LDL, HDL andplasma triglyceride of mice in the end of treatment. Simvastatin and aquadest were separately used as positive andnegative control. This research proves that shallot’s extortion water has effect in decreasing the level of total cholesterol,LDL and triglyceride and also has effect in increasing level of HDL plasma with 80% of concentration as the bestconcentration.
Resistensi Aedes aegypti terhadap Insektisida Golongan Organofosfat Lesmana, Suri Dwi
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.33 KB) | DOI: 10.26891/JIK.v4i1.2010.10-13

Abstract

Dengue haemorrhagic fever (DHF) is one of Indonesian public health problems because of its high incidence rate.DHF control is emphasized on vector control Aedes aegypti by using insecticide. Organophosphate has been used asinsecticides to control the dengue vectors for more than 25 years ago. The using of insecticide in long time andsublethal dose can induce insecticide resistance. Aedes aegypti resistance of organophophate have occured based onfisiologic and genetical mechanisms. The major mechanism of resistance to organophosphate insecticides in Aedesaegypti is genetical mechanism. The two major forms of genetical resistance are target site resistance which occurswhen the insecticide no longer binds to its target and detoxification enzyme based resistance through highly activenon specific esterase enzyme.
Uji Toksisitas Akut Ekstrak Etanol Daun Sapu Jagad (Isotoma longiflora (L) Presl.) pada Mencit Galur Mus muculus Safitri, Ira; Inayah, Inayah
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (87.525 KB) | DOI: 10.26891/JIK.v4i1.2010.42-47

Abstract

Sapu Jagad (Isotoma longiflora (L) Presl.) plant has been empirically used as traditional medicine. Some studies showthat this plant has pharmacological effects as antibiotic, anticancer, and analgetic. It is of importance to conduct studyin finding out the safetiness of this plant as herbal medicine. Therefore, we conducted study to find out lethal dose ofits leaves on mice (Mus muculus) using acute toxicity test. Several doses have been given to certain groups to find outits effect including death. The extract has been given one time per oral. Then, we recorded the clinical signs and deathof mice until 14 days. The data was analyzed using probit analysis to measure LD50. This study shows that ethanolextract of Sapu Jagad leaves has LD50 12.610 mg/kgBW and toxicity of central nervous system proven by seizureending with death. As conclusion, this extract has toxicity especially to central nervous system.
Antagonis Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) dan Soluble Endoglin (sEng) pada Preeklamsia Andalas, Mohd; Harahap, Harahap
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (122.088 KB) | DOI: 10.26891/JIK.v4i1.2010.1-9

Abstract

Proangiogenic factor signal transduction like vascular endothelial growth factor (VEGF), placental growth factor(PlGF) and tissue growth factor â-1 (TGFâ-1) are important to angiogenesis and vascular health in pregnancy. Inpreeclampsia (PE) concentration of fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sEng) are increasesignificantly. Base on analysis from resent research shown that sFlt-1 and sEng inhibit angiogenic factor signaltransduction by competition - in result angiogenic factor can‘t bind to their receptor. sFlt-1 and sEng are potential usedas preeclampsia therapy because sFlt-1 and sEng have main role in PE pathogenesis. We suggest that the research tofind out effective sFlt-1 and sEng antagonist have to conduct in the next time.
Hubungan Respon Imun Humoral dengan Derajat Trombositopenia pada Pasien Demam Berdarah Dengue Fatmawati, Fatmawati; Wijaya, Chandra
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (40.156 KB) | DOI: 10.26891/JIK.v4i1.2010.36-41

Abstract

The correlation between humoral immune response with the level of of thrombocytopenia on dengue hemorrhagicfever patient The aim of this study was to know the correlation between humoral immune response with the level of ofthrombocytopenia on dengue hemorrhagic fever patient. This is a cross sectional analytical study on internal inpatientsof AwalBros Pekanbaru Hospital in August-November 2008. Population was all internal inpatients of AwalBros PekanbaruHospital with working diagnosis dengue hemorrhagic fever. There were 4 pattern of anti Dengue antibody : IgG-/IgM,IgG-/IgM+, IgG+/IgM-, IgG+/IgM+. Most of patients with IgG+/IgM+ and have secondary dengue infection Thoseresult were analyzed by Friedman statistical test. There isn’t a significant correlation between the level ofthrombocytopenia and anti dengue antibody. It show that there wasn’t a direct correlation between them. It could bedue to a cross reaction between anti dengue antibody with thrombocyte (autoantibody).
Faktor-Faktor yang Mempengaruhi Kejadian Pedikulosis Kapitis pada Murid Kelas III, IV, V Dan VI SDN 019 Tebing Tinggi Okura Kecamatan Rumbai Pesisir Pekanbaru Zulinda, Aprilia; Yolazenia, Yolazenia; Zahtamal, Zahtamal
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (41.18 KB) | DOI: 10.26891/JIK.v4i1.2010.65-69

Abstract

Pediculosis capitis disease spread on to the whole world and found mostly in people with low in hygiene and socioeconomic.This Pediculosis capitis could be found in all age people especially in student age. The purpose of thisresearch was to know description the factors that affect Pediculosis capitis case in IIIrd, IVth, Vth and VIth graders ofSDN 019 Tebing Tinggi Okura in Rumbai Pesisir subdistrict of Pekanbaru. This cross sectional research had beendone in March until August 2009 period. Sampel examination was done in macroscopicaly using serit comb to find thelouse eggs and mature louses. From this study, 53 (39,3%) of 135 sampel student were infected by Pediculus humanuscapitis. Based on data analyses, there were known that sex, hair length, parents education, social and economicalcondition of the family, hair washing frequence, using tools related to hair together and comb cleaning custom variableshad significant relation that affect Pediculosis capitis (p<0,05).
Faktor-faktor yang Mempengaruhi Partisipasi Mahasiswa dalam Proses Tutorial pada Metode Belajar Problem-Based Learning (PBL) di Fakultas Kedokteran Universitas Riau Hamidy, M Yulis; Asni, Enikarmila
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (52.039 KB) | DOI: 10.26891/JIK.v4i1.2010.30-35

Abstract

Problem-based Learning (PBL) is an effective approach to promote student-centered learning. PBL tutorials were thekey step in PBL process. Students’ participation in PBL tutorials can be influenced by many factors. The aim of thisstudy was to identify the factors that influence students’ participation in PBL tutorials among students in Faculty ofMedicine University of Riau. The research was a cross sectional study using self report questionnaires obtained fromPBL students, conducted in April - October 2009. The students’ participation was assessed using Visschers-Pleijersquestionnaires. The result revealed the characteristics of parcipants which are female (79.5%), 19 years old (40.2%),had GPA 2.50 – 3.00 (56.7%), had past experience in organization (89.0%). Among 44.1% of the participants showedactive participation in tutorial processs. Male students more likely active than female students (P = 0.045). Anotherfactors including age, GPA, past experience in organization, role of tutors, and quality of scenario were not influencedthe participation of subject. Students’ participation in PBL tutorials among students in Faculty of Medicine Universityof Riau was influenced by sex.
Analisis Faktor Perilaku Kaitannya dengan Permasalahan Pelayanan Kesehatan Ibu dan Anak (KIA) di Provinsi Riau Zahtamal, Zahtamal; Restuastuti, Tuti; Chandra, Fifia
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (76.218 KB) | DOI: 10.26891/JIK.v4i1.2010.20-29

Abstract

The low of health community status for this time is still health problems in Indonesia, marked with the high maternalmortality and infant mortality rate. According to health survey, there are still many indicators of maternal, newbornand child health (MNCH), show low achievement. The aim of this study was to find the situation of MNCH servicesand to describe determining factors of the problems in Riau Province. Method of this research was a descriptive designwith quantitative and qualitative data. Result obtained in this research described that some indicators of MNCH servicesperformance were achievable and some were not. The profile of community on health behavior about maternal healthwas shown with good knowledge, neutral attitude, and good practice. Then, the profile of community health behaviorabout newborn and child health was shown with middle level of knowledge, positive attitude, and good practice. Keyperson, mostly categorized as a decision maker for health action was husband/wife. Viewed from quickly action onresponse of sick/unhealthy family members for MNCH services indicated that there was not late decision. There werestill many communities’ beliefs, not match with health value, especially for MNCH.

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