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Contact Name
Ilhami Romus
Contact Email
ilhamiromus@yahoo.co.id
Phone
+6281371333123
Journal Mail Official
jikfkunri@gmail.com
Editorial Address
Sekretariat JIK (Jurnal Ilmu Kedokteran) Jl. diponegoro no. 1, Pekanbaru Riau
Location
Kota pekanbaru,
Riau
INDONESIA
Jurnal Ilmu Kedokteran
Published by Universitas Riau
ISSN : 1978662X     EISSN : 27154467     DOI : https://doi.org/10.26891/JIK
Core Subject : Health, Science,
Journal of Medical Science receives a script from health and medical lecturer, undergraduate, residents, hospital staff and those who interested in writing scientific papers. The scientific articles posted on JIK include: literature reviews, research article, case report and EBCR (Evidence Based Case Report). Article preferably basic science of medicine and health.
Articles 9 Documents
Search results for , issue "Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran" : 9 Documents clear
Pengaruh Hemodialisis Terhadap Kadar Glutation Tereduksi (GSH) Plasma Pasien Hemodialisis RSUD Arifin Ahmad Anami, Hannan Khairu; Butar-Butar, W. Ristua; Asni, Enikarmila
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (37.858 KB) | DOI: 10.26891/JIK.v5i1.2011.13-18

Abstract

Chronic kidney disease patients who received hemodialysis therapy have higher risks to get atherosclerosis, inflammation,and cancer than general population at the same age. Imbalance of free radicals level and antioxidants defense whichdefined as oxidative stres may cause these complications. This study investigated the influence of hemodialysis onreduced glutathione (GSH) level, one of antioxidant, in blood plasma of hemodialysis patient at RSUD Arifin Ahmad.This was a cross sectional study that compare plasma GSH level before and after hemodialysis process. Population ofthis study was 72 patient in RSUD Arifin Ahmad but only 17 patient fulfilled all the inclusion and exclusion criteria.Plasma GSH level was measured by using Ellman method. The result showed that there were no significant differenceof plasma GSH level in patient before and after hemodialysis process (p=0,426).
Hubungan Antara Pengetahuan dan Sikap Terhadap Tindakan Pencegahan Penyakit Chikungunya pada Keluarga di Desa Kepenuhan Timur , Kec. Kepenuhan, Kab.Rokan Hulu, Propinsi Riau. Restuastuti, Tuti; Yuliawati, Yuliawati; Lesmana, Suri Dwi
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (47.797 KB) | DOI: 10.26891/JIK.v5i1.2011.41-48

Abstract

Chikungunya is a viral illness that is caused by Chikungunya virus and transmitted by Aedes sp. The purpose of thisresearch was to determine the relationship between knowledge and attitude with practice of chikungunya diseaseprevention to families in Kepenuhan Timur village Kepenuhan Subdistrict Rokan Hulu regency. The method of thisresearch was analytic crossectional study. The sample size were 230 families. The amount of subject were determindusing simple random sampling. The data were collected by using questionaires. The results of this research showedthat 64,3% of respondent had lack of knowledge, 99,1% of respondent had positive attitudes and 84,8% of respondentshad negative behavior in chikungunya disease prevention. There was no significant relationship between knowledgeand attitudes with practice of chikungunya disease prevention in Kepenuhan Timur village with p value > 0,05.
Perancangan Objective Structured Clinical Examination (OSCE) untuk Menilai Kompetensi Klinik Zulharman, Zulharman
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (59.467 KB) | DOI: 10.26891/JIK.v5i1.2011.7-12

Abstract

When planned and organized correctly, OSCE can be highly successful as an instrument to assess competence inmedicine. Knowledge about how to plan and organize OSCE is required by OSCE’s designers in medical education, sothat OSCE which had been designed become valid, reliable and feasible. The elements in designed OSCE consisted ofdefining of clinical competency which be assessed, design station, patient, examiners, pass or fail scoring, logistics andcosts.
Pengaruh Pemberian Jus Semangka (Citrullus vulgaris Schard.) Peroral Terhadap Jumlah Spermatozoa Mencit (Mus musculus) Yang Dipapar Asap Rokok Elwinda, Lusy; Amtarina, Rina; Hamidy, M.Yulis
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (64.916 KB) | DOI: 10.26891/JIK.v5i1.2011.35-40

Abstract

Infertility is influenced by many factors, one of them is reactive oxygen species (ROS) containing free radicals. Freeradicals can be neutralized by antioxidants. Watermelon (Citrullus vulgaris Schard.) contains compounds with strongantioxidant activity so that protect the spermatozoa from the toxic effects of ROS. The purpose of this research was todetermine the effect of watermelon juice to the number of spermatozoa’s mice exposed by cigarette smoke. Its designwas the post test only, while the subjects were 20 male mices, which divided into five groups were baseline, K(-), P1,P2 and P3. This experimental study lasted for 14 days. On the 15th day, all mice were terminated and the number ofspermatozoa was examinated. One way anova test showed significant differences of spermatozoa count between groups(p=0,000). Based on post hoc test there were significant differences between group of baseline with K(-) and P1,between group of K(-) with P2 and P3, and between group of P2 with P1 and P3. This study showed that watermelonjuice increased the number of spermatozoa in mice exposed by cigarette smoke and dose 0.32 ml/day gave the besteffect.
Epidemiologi Kriptosporidiosis Maryanti, Esy
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.923 KB) | DOI: 10.26891/JIK.v5i1.2011.1-6

Abstract

Cryptosporidiosis is a disease caused by Cryptosporidium sp. Cryptosporidium sp. are single cell of coccidian caninfected human and animals. Cryptosporidiosis are considered a cause of emerging and opportunistic infections inhuman. Oocysts of Cryptosporidium are ovoid or spherical and 4 to 6 micrometers diameters. The parasite is located inthe brush border of the epithelial cells of the small intestine. Currently, eight species of Cryptosporidium are known toinfect human and there are two species, C parvum and C muris which most common species reported to infect childrenand immunocompromised patient especially AIDS patient with diarrhea.
Pengaruh Pemberian Antioksidan Vitamin C Dan E Terhadap Konsentrasi Spermatozoa Mencit (Mus Musculus) Yang Dipapar Asap Rokok Harahap, Ervina Wati; Sandora, Normalina; Winarto, Winarto
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.553 KB) | DOI: 10.26891/JIK.v5i1.2011.26-34

Abstract

Free radical that are released in cigarette smoke, believed to play an important role in male infertility. The free radicalproduces Reactive Oxygen Species (ROS) that is found increased in male smokers. ROS is one of the free radicalscomponent can be neutralized by vitamin C and E as an antioxidant. This study using those agents to the fifteen minuteshalf piece cigarette to expose mice and count their sperm as the fertilility parameter. The research design used was posttest-only control group with twenty mice were divided into five groups. A group of no smoke exposed was categorizedas a baseline control, the exposed groups were consisted of one group without antioxidant, one group with vitamin Ctreatment, a group of vitamin E treatment and at last the combination of vitamin C and E. All groups were treatedfor fourteen days. The results were analyzed using oneway ANOVA with p<0.05. It is obviously proven that thecombination of vitamin C and vitamin E treatment on the usual dose gave the highest sperm count compared to othergroups.
Perbandingan Efek Pemberian Emulsi Kedelai dan Emulsi Tempe Terhadap Hitung Limfosit Total pada Tikus Putih yang Telah Diberi Prednison Nurcahyani, Rizka Bekti; Pardede, Imelda T; Masdar, Huriatul
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (44.35 KB) | DOI: 10.26891/JIK.v5i1.2011.56-62

Abstract

Adequate nutrition is one of important factors in immunodeficiency repairment. Soybean and tempeh contains proteins,zinc, ferrum, vitamins and isoflavon. Fermentation in tempeh makes it having better nutrients digestion and absorptionthan soybean. The objective of this study was to compare the effects of soy and tempeh emulsions on total lymphocytecount in rats treated with prednisone. The test was done on 24 male white rats divided into four groups. Group A wasgiven distilled water and group B, C and D had prednisone 2.5 mg/day for 6 days. After that, group A and B werecontinued having distilled water while groups C or D was fed with soy or tempeh emulsion 0.71 mL/day for 10 days,respectively. The results shown that soy and tempeh emulsion could increase total lymphocyte count significantly (p <0,05) but there was no significant difference of total lymphocyte count between soy and tempeh emulsion groups (p >0,05).
Pencegahan Lesi Aterosklerosis Oleh Asam Alfa Lipoat Pada Aorta Mencit Jantan (Mus Musculus) Yang Diberi Diet Tinggi Kolesterol Ismawati, Ismawati; Winarto, Winarto; Sari, Rezki Permata
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.53 KB) | DOI: 10.26891/JIK.v5i1.2011.19-25

Abstract

Atherosclerosis can happen easily on animal that are given high cholesterol diet. Alpha lipoic acid is universal antioxidantthat very effective to reduce free radicals, include lipid peroxide. The goal of this research was to find out the prohibitionof atherosclerosis lesion development on male mice aorta that was given high cholesterol diet by alpha lipoic acid. Thiswas an experimental laboratory research with post test only design. Eighteen adult male mice were segregated intothree groups labelled as group NaCl 0,9%, yolks and ALA.. The experiment was design for 6 weeks. The measuredparameter was atherosclerosis lesion score of groups labelled. The statistical test result showed the significant differenceof some tested groups. There was a statistically significant difference between alpha lipoic acid and yolks group (p=0,008),but there is no significant difference was found between ALA and NaCl 0,9% group (p=0,126). As the conclusion, thisstudy proves that alpha lipoic acid has the effects to prohibition of atherosclerosis lesion development on male miceaorta that are given high cholesterol diet.
Analisis Mutasi Gen SRY dan AZF serta Fungsi Gonad pada Penderita 46,XY Disorder of Sex Development (DSD) Erawati, Meira; Winarni, Tri Indah; Juniarto, Ahmad Zulfa; Santosa, Ardy; Faradz, Sultana MH
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (83.535 KB) | DOI: 10.26891/JIK.v5i1.2011.49-55

Abstract

Disorder of sex development (DSD) includes congenital conditions in which development of chromosomal,gonadal or anatomy of urogenital is atypical. SRY and AZF genes have relationships with sex development andfertility in 46,XY DSD patients. Therefore, the condition of those genes and gonadal function on 46,XY DSD patientsare needed to be explored deeply. The aim of this study was to know the incident number of SRY and AZF genes andgonadal function of 46,XY DSD patients. So that it can be used as one of basic analyses of DSD and infertility statuson 46,XY DSD patients .Methods: This is an observational descriptive study with cross sectional approach. This study involved 36 patientsthat fulfilled the criteria of 46,XY DSD. The DNA of each sample was analyzed by PCR electrophoresis. The data ofhCG stimulation test were obtained from secondary data of patient’s medical record.Results: A hundred percent (100%) of 36 samples did not have deletion on their SRY gene. About 22,22% of sampleshad AZFa gene deletion especially on STS sY84. There were 19,44% samples that showed negative response to hCGstimulation test. Chi square test showed that AZFa deletion did not have relation with gonadal response positifity on46,XY DSD patients.Conclusion: Patients of 46,XY DSD need to be evaluated for their fertility especially on the sperm analysis afterreaching puberty period. It is done to patients with positive or negative gonadal responses to know whether infertilityis influenced by AZF gene or other factors.

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