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Berkala Ilmu Kedokteran
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Articles 10 Documents
Search results for , issue "Vol 13, No 04 (1981)" : 10 Documents clear
Some physiological aspects of gastric ulcer Harjani, Harjani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (623.151 KB)

Abstract

The key of the development of gastric ulcer is that the unionised substances or the lipid soluble substances which can cross the lipoprotein part or the cell membrane cause a rapid back diffusion of H-ions from the lumina I part of the stomach to the mucosa] layer, and a rapid Na-ions secretion. It causes cell damage and histamin release. Histamin causes mucosal edema and increases gastric acid secretion. Strong and repeated insults of histamin release may develop mucosal erosions and then ulcers.It is suggested that the development of gastric ulcer is promoted among others by acid hypersecretion, mucous hypersecrerion, delayed mucosal cell turn-over, SIgA deficiency, rnucosal exposure to mucosa] damaging substances, and prolonged and repeated mucosa] ischemia.The pain of gastric ulcer is probably due mainly to the action of acid or other irritants on a sensitive region of the mucous membrane.Key Words : gastric mucosal barrier - I-12 receptor - cephalic phase of gastric secretion - emotional stress - cigarette smoker
The ethics of scientific research T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.157 KB)

Abstract

Considering the importance of scientific ethics in research, especially if it involves human experimentation, the author discUsses various ethical points in conducting research from the preparation of research until the publication of its results. Emphases are placed upon responsibility CO the source of information, colleagues, research material, both human and animal, and humanity at large; scientific objectivity; and intellectual honesty.The need for research ethics cannot be overemphasized since deviation from the ethical principles are currently occurring even in the scientifically most advanced countries, due to, among others, the publish or perish" principle, pressure from funding agencies and research institutions, professional rivalries between individuals or institutions, and fights for priorities of discoveries and inventions.In the less developed countries the deviations are more elementary, but with the increasing quantity of research, complex problems are making their debut.Key Words: scientific ethics - human experimentation - informed consent - research review board - scientific objectivity
Binocular cataract extraction with local anaesthetic A. Soemarsono, A. Soemarsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.929 KB)

Abstract

The results of binocular cataract extraction with local anaesthetic are presented, which are good enough and not different compared with monocular cataract operations in The Eye Hospital of Gadjah Mada University. By binocular cataract extraction the hospital stay of the patient is very short and is less expensive compared with one by one operation.Key Words: binocular cataract extraction - cataracts senilis - corpus vitreum zonulysis - glaucoma
Clinical experience with Clonidine in the treatment of hypertension Ahmad H. Asdie, Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.961 KB)

Abstract

In this article we reported our experience with Clonidine in treating hypertensive patients in the Department of Internal Medicine, Gadjah Mada University Hospital, Pugeran, Yogyakarta. 25 patients suffering from severe or moderate hypertension of 13 females and 10 males were included in the study. The treatment began with a small dose of 0.075 mg bid. This dose if necessary was increased every 3-7 days. In some patients diuretics were added.Side effects and effect of treatment on the blood pressure are described and discussed.Key Words: hypertension - clooidine - diuretics - renal failure - antihypertensive drugs
Gangguan Kosmetik Karena Kelainan Pigmentasi Kulit Hardyanto, Hardyanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (357.968 KB)

Abstract

Patients with pigmentary changes on their skin seek advise primarily for cosmetic reasons, although these are usually asymptomatic and without systemic consequencei. The most common types of pigmentary disturbances are freckles, melasma, lentikines, melanoderma, vitiligo and leukoderma.This article discusses normal melanogenesis, and clinical features, pathogenesis and treatment of pigmentary abnormalities of the skin,Patients suffering from pigmentary abnormalities attending the clinic of the Department of Dermatology and Venereology, Gadjah Mada University Hospital, are presented, From 1978 to 1979, 450 patients were noted. 26% males and 74% females, with the following breakdown: 18.2% melasma, 20.2% freckles, 12.4% melanoderma, 6.4% lentigo, 84.7% vitiligo and 8.1% leultoderma . -Key Words: pigmentary abnormalities - hyperpigmentation and hypopigmentation - epidermal melanin unit - hydrocluinon - psoralen
Some physiological aspects of gastric ulcer Harjani, Harjani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (623.151 KB)

Abstract

The key of the development of gastric ulcer is that the unionised substances or the lipid soluble substances which can cross the lipoprotein part or the cell membrane cause a rapid back diffusion of H-ions from the lumina I part of the stomach to the mucosa] layer, and a rapid Na-ions secretion. It causes cell damage and histamin release. Histamin causes mucosal edema and increases gastric acid secretion. Strong and repeated insults of histamin release may develop mucosal erosions and then ulcers.It is suggested that the development of gastric ulcer is promoted among others by acid hypersecretion, mucous hypersecrerion, delayed mucosal cell turn-over, SIgA deficiency, rnucosal exposure to mucosa] damaging substances, and prolonged and repeated mucosa] ischemia.The pain of gastric ulcer is probably due mainly to the action of acid or other irritants on a sensitive region of the mucous membrane.Key Words : gastric mucosal barrier - I-12 receptor - cephalic phase of gastric secretion - emotional stress - cigarette smoker
Binocular cataract extraction with local anaesthetic A. Soemarsono, A. Soemarsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.929 KB)

Abstract

The results of binocular cataract extraction with local anaesthetic are presented, which are good enough and not different compared with monocular cataract operations in The Eye Hospital of Gadjah Mada University. By binocular cataract extraction the hospital stay of the patient is very short and is less expensive compared with one by one operation.Key Words: binocular cataract extraction - cataracts senilis - corpus vitreum zonulysis - glaucoma
Clinical experience with Clonidine in the treatment of hypertension Ahmad H. Asdie, Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.961 KB)

Abstract

In this article we reported our experience with Clonidine in treating hypertensive patients in the Department of Internal Medicine, Gadjah Mada University Hospital, Pugeran, Yogyakarta. 25 patients suffering from severe or moderate hypertension of 13 females and 10 males were included in the study. The treatment began with a small dose of 0.075 mg bid. This dose if necessary was increased every 3-7 days. In some patients diuretics were added.Side effects and effect of treatment on the blood pressure are described and discussed.Key Words: hypertension - clooidine - diuretics - renal failure - antihypertensive drugs
Gangguan Kosmetik Karena Kelainan Pigmentasi Kulit Hardyanto, Hardyanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (357.968 KB)

Abstract

Patients with pigmentary changes on their skin seek advise primarily for cosmetic reasons, although these are usually asymptomatic and without systemic consequencei. The most common types of pigmentary disturbances are 'freckles, melasma, lentikines, melanoderma, vitiligo and leukoderma.This article discusses normal melanogenesis, and clinical features, pathogenesis and treatment of pigmentary abnormalities of the skin,Patients suffering from pigmentary abnormalities attending the clinic of the Department of Dermatology and Venereology, Gadjah Mada University Hospital, are presented, From 1978 to 1979, 450 patients were noted. 26% males and 74% females, with the following breakdown: 18.2% melasma, 20.2% freckles, 12.4% melanoderma, 6.4% lentigo, 84.7% vitiligo and 8.1% leultoderma . -Key Words: pigmentary abnormalities - hyperpigmentation and hypopigmentation - epidermal melanin unit - hydrocluinon - psoralen
The ethics of scientific research T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.157 KB)

Abstract

Considering the importance of scientific ethics in research, especially if it involves human experimentation, the author discUsses various ethical points in conducting research from the preparation of research until the publication of its results. Emphases are placed upon responsibility CO the source of information, colleagues, research material, both human and animal, and humanity at large; scientific objectivity; and intellectual honesty.The need for research ethics cannot be overemphasized since deviation from the ethical principles are currently occurring even in the scientifically most advanced countries, due to, among others, the ''publish or perish" principle, pressure from funding agencies and research institutions, professional rivalries between individuals or institutions, and fights for priorities of discoveries and inventions.In the less developed countries the deviations are more elementary, but with the increasing quantity of research, complex problems are making their debut.Key Words: scientific ethics - human experimentation - informed consent - research review board - scientific objectivity

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