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Jurnal Teknosains
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Core Subject : Engineering,
JOURNAL TEKNOSAINS, is a journal which began publication in 2011, and is published each June and December. JOURNAL TEKNOSAINS is a series of scientific publications in science and technology area from the perspective of a multi and interdisciplinary studies. JOURNAL TEKNOSAINS is an interdisciplinary forum for the publication of original peer-reviewed, contributed and invited articles to improve and enhance science and technology. The journal provides a stimulating and informative variety of papers geared toward theory and practice in the hope that common information shared among a broad coalition of individuals and groups involved in science and technology will facilitate future efforts. JOURNAL TEKNOSAINS published by the Graduate School of Gadjah Mada University. All articles will be subjected to double-blind peer review process following a review by the editors.
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Articles 8 Documents
Search results for , issue " Vol 2, No 1 (2012): December" : 8 Documents clear
Karakteristik Toksisitas Hidroksiapatit yang Disintesis dari Kalsit Terhadap Rattus norvegicus Isti Rahayu Suryani, Siti Sunarintyas dan
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (709.299 KB) | DOI: 10.22146/teknosains.5987

Abstract

The use of synthetic hydroxyapatite (HA) in biomedical application is well warranted. It has shown to havean excellent biocompatibility in human tooth and bones. The present study was conducted to know the toxicitycharacteristics of hydroxyapatite synthesized from Mojokerto calcite in Rattus norvegicus. In this study 30Rattus norvegicus were used as experimental animals. The animals were divided into 3 groups (n=10) to be givenHA-calcite, HA-200 (Waco, Japan), and aquadest (control) orally. The animals were observed 7 days and thenwere analyzed for: fatality rate and clinical behavior, hematology test, organ morphology, and histopathologyappearance. The result showed that there was not any animal death during 7 days observation. None of the animalexhibited any noteworthy findings in clinical behavior, hematology test, organ morphology, and histopathologyappearance. In conclusion, HA-calcite did not show any acute toxicity characteristic; therefore, it was potential tobe used as an alternative material for bone substitution.
PROSES PENGELOLAHAN MENINGKATKAN AKTIVITAS HIPOLIPIDEMIK JAMUR TIRAM (PLEUROTUS OSTREATUS) PADA TIKUS (RATTUS NORVEGICUS) SPRGUE-DAWLEY HIPERKOLESTEROL Sri Anggrahini dan Sutikarini, Eni Harmayani, Deera Army Pramana,
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (527.688 KB) | DOI: 10.22146/teknosains.5981

Abstract

Oyster mushroom is considered to have hypocholesterolemic and hypolipidemic activities. Therefore, it is classifiedas functional food. Prior to serving and consumption, oyster mushroom can be processed in various ways. Thisresearch studied the effect of three kinds of processing commonly used in cooking oyster mushroom; boiling,frying, and roasting. Thirty Sprague-Dawley male rats, 8 weeks old, were acclimated to laboratory condition,and then induced with high lipid diet. The rats were divided into five experiment groups; high-lipid diet (K),high-lipid diet + raw oyster mushroom (M), high-lipid diet + fried oyster mushroom (G), high-lipid diet + roastedoyster mushroom (P), and high-lipid diet + boiled oyster mushroom (R). Blood samples were obtained from orbitalplexus after acclimation, hypercholesterolemic induction, and 21 days of feeding. The blood serum was examinedfor total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-c), dan high-densitylipoprotein cholesterol (HDL-c). The result showed that cooked oyster mushroom had better hypocholesterolemicand hypolipidemic activity than raw oyster mushroom. Among the three, the roasted oyster mushroom reduced thetotal cholesterol the most, while boiled oyster mushroom reduced triglyceride the most.
SPECIES COMPOSITION OF AMPHIBIAN IN GUNUNGKELIR STREAM, JATIMULYO VILLAGE, KULON PROGO dan Trijoko, Tony Febri Qurniawan
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (477.395 KB) | DOI: 10.22146/teknosains.5988

Abstract

Gunungkelir stream is located in Jatimulyo village, western part of Daerah Istimewa Yogyakarta Province.The ecosystem that surrounds Gunungkelir stream looks natural and unpolluted, it is possible for good livingenvironment of amphibians. However, the database about diversity of Amphibians in Gunungkelir stream hasnot been revealed. This research was done to study species diversity, species richness, species composition anddistribution of amphibians in Gunungkelir stream as an effort to support the sustainability of amphibians livefrom extinction. The research was done on January-May 2009, at night. The VES (Visual Encounter Survey)method with line transects 250 m were used. A total 11 species of amphibians from 6 different amphibia familieswere identified. Phrynoidis aspera, Leptobrachium hasseltii and Hylarana chalconota are dominant species. Thehigest percentage of amphibians population was tadpole (38%), followed by male (35%), female (21%), and theleast were juvenile (6%). During the survey, different species of amphibians were observed with their own rangeof spatial distribution.
ANALISIS DAN PROFIL TINGKAT KEBUGARAN MAHASISWA JURUSAN TEKNIK MESIN DAN INDUSTRI UNIVERSITAS GADJAH MADA YOGYAKARTA dan Chusla Rosdiana Dewi, Herianto
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (468.339 KB) | DOI: 10.22146/teknosains.5982

Abstract

Aerobic fitness can be used as a health indicator. The purpose of this study is to investigate the effect of Body Mass Index,gender, and physical activity on the aerobic fitness. Twenty females and 27 males students in range of 20 ± 1.2 yearsold, height 164 ± 8.95 cm, and weight 58.23 ± 9.5 kg that meet inclusion criteria were used as subject that measuredin Ergonomics Laboratory Gadjah Mada University within room temperature 25-26oC and 40-50% in humidity.Four methods of indirect measurement (VO2max as an output) is used to measure aerobic fitness: nonexercise skinfoldmeasurements and Body Mass Index, Astrand bicycle, treadmill, and the fitness index Harvard Step Test performed ondifferent days. The results showed that gender (rs = 0.838 on the nonexercise BMI) and BMI (rs = -0.677 on the Astrandmethod) effect on aerobic fitness. The average value of VO2max (ml.kg-1.min in-1) is achieved from each method. Formale, Astrand bicycle = 53.24 ± 7.82, treadmill = 38.43 ± 9, 05, BMI = 44.85 ± 3.45, 42.49 ± 3.38 = skinfold. Forwomen, Astrand bicycle = 47.86 ± 8.59, ± 5.73 treadmill = 34.1, BMI = 34.25 ± 2.46, 34.63 ± 2.51 = skinfold.
Janeway’s Immunobiology Soesatyo, Marsetyawan HNE
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.33 KB) | DOI: 10.22146/teknosains.5992

Abstract

Buku teks imunologi sudah cukup banyak beredar di tanah air. Buku-buku tersebutmenguraikan tentang sistem dan mekanisme pertahanan tubuh dalam interaksinya denganlingkungan di luar tubuh yang penuh akan mikroba dan patogen penyebab infeksi.Pengetahuan imunologi tubuh manusia terus berkembang dengan cepat, luas, dan mendasar.Hal ini disebabkan karena dukungan pengetahuan lain yang terkait, baik aspek teoritismaupun teknik-teknik laboratoris canggih yang menyentuh aras selular dan molekular.Kemudian memunculkan temuan-temuan baru yang spektakuler, bahkan tidak jarangdengan bukti terbaru telah menggugurkan teori-teori lama. Setiap makluk hidup, khususnyamammalia termasuk manusia, sudah dilengkapi dengan sistem pertahanan tubuh sejak lahir,bahkan komponen-komponen penyusun dalam sistem imun tersebut sebagian sudah ada dandisiapkan sejak kehidupan intra-uterin. Imunitas seperti ini masuk dalam ranah ‘alamiah’atau ‘innate’, sementara imunitas tubuh yang terus berkembang mulai lahir sampai dewasadipengaruhi langsung oleh lingkungan sekelilingnya. Imunitas yang didapat ini termasukdalam ranah ‘adaptif’
KAJIAN PENCEMARAN LINGKUNGAN DI TAMBAK UDANG DELTA MAHAKAM Eko Sugiharto, Salahuddin, Chafid Fandeli, dan
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (753.163 KB) | DOI: 10.22146/teknosains.5986

Abstract

well-managed, it will contribute to the improvement of both regional and national economy. However, MahakamRiver gets liquid waste pollution that has significant impact on water quality and results in conflicts betweenthe local societies, especially the shrimp pond farmers and the fishermen and the oil and gas industrial company.This research uses descriptive-comparative analysis with ANOVA test to compare samples (water, soil/sediment,shrimp, and mangrove) of the shrimp fishpond (many mangrove, moderate mangrove, few mangrove, and withoutany mangrove). The pollution load which is analyzed includes: cadmium content (Cd), lead (Pb), oil and grease (O& G), mercury (Hg), and arsenic (As). The significance level is 90% with error of 5% (0.05).The water of Mahakam Delta is still in the normality limit as seen from the maximum pollution load in the Decreeof the Minister of Living Environment No. 51 of 2004 on Ocean Water Standard seen from chemical, physical,and biological parameters. The presence of mangrove contributes positive value to the balance of the quality of thewaters and to the neutralizing of heavy metals contents of Mahakam Delta as shown in the average difference inthe Pb, Cd, O & G, As and Hg of the samples of water, soils/sediment, shrimp and mangrove which are drawnfrom the of shrimp pond with many mangrove, moderate mangrove, few mangrove and without any mangrove,which is significantly different (p < 0.05). Shrimp pond with many mangrove has less average levels of Pb, Cd, M& L, As and Hg compared with the pond with less and without mangrove. The shrimp pond with many mangrovescontributes significantly and positively to the prevention of the pollution of Pb, Cd, O and G, As and Hg at low level
ANALISIS INTANGIBLE FACTORS YANG MEMPENGARUHI PENENTUAN HARGA PRODUK KARYA SENI Lestariningsih, Kusriniarti Dwi
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.83 KB) | DOI: 10.22146/teknosains.5990

Abstract

This research aims to develop a new quantitative method to determine painting pricing based on 10 intangible factors, i.e. curator, amount of exhibition, painter’s year of birth, painting’s years of made, auction record,estimation price, exhibition place, painting media, painting size, and previous sales record. The selling price data are obtained from six auction houses. Kano Model and Linear Regression Model are used to examine the relationbetween pricing and each variable. Based on the model development scheme, there are 6 alternative models that can be obtained. Each model then was evaluated by cross-validation procedure using 21 data. Based on the value of R2for each model, the Kano Model with variable previous sales is the best model with R2 of 70%
IDENTIFIKASI EFEK DEPRESAN SSP (SUSUNAN SARAF PUSAT) ANTIKEJANG DAN NEUROTOKSISITAS SENYAWA 4-KLOROBENZOILTIOUREA PADA MENCIT PUTIH JANTAN dan Dini Kesuma, Aguslina kirtishanti
Jurnal Teknosains Vol 2, No 1 (2012): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (554.853 KB) | DOI: 10.22146/teknosains.5980

Abstract

The study on the development of benzoylthiourea derivatives as central nervous system (CNS) depressants was based on their structure, which contains acyclic ureide, an isosteric group of CNS depressant drugs common structure. The study was carried out by modifying the structure of benzoylthiourea using the Topliss model based on the enhancement of its lipophilic and electronic properties. It is predicted that the product will give higher activity than the parent compound. In this study, identification of CNS depressant, anticonvulsant and neurotoxicity effects of the compound synthesized, i.e. 4-chlorobenzoylthiourea, was conducted. The identification of CNS depressant effects was done using Barbiturate Sleeping Time, the identification of anticonvulsant effects was done using Maximum Electroshock Seizure and the identification of neurotoxicity effect was done using rotarod in mice (Mus musculus). This study used five groups of mice: a control group, a standard group (Phenobarbital Na) and 3 treatment groups with doses of 15 mg/kg, 45 mg/kg and 75 mg/kg respectively. From the results, it can be concluded that 4-chlorobenzoylthiourea gives the best CNS depressant, anticonvulsant and neurotoxicity effects at the doses of 75 mg/kg, 15 mg/kg and 45 mg/kg respectively. 

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