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Nexus Kedokteran Klinik
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Articles 334 Documents
PERBEDAAN PENURUNAN FUNGSI KOGNITIF PADA PASIEN STROKE ISKEMIK LESI HEMISFER KANAN DAN KIRI DI RSUD DR. MOEWARDI Sitaresmi, Adya; Widjojo, FX Soetedjo; Ghozali, Dhoni Akbar
Nexus Kedokteran Klinik Vol 3, No 3 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Stroke is a major health problem in many parts of the world and is increasing in prevalence in line with modernization. Damage to brain cells after stroke cause cognitive function disability that affect the quality of life and independence of the patient. Decline in cognitive function relates to size and location of the lesion. This research aims to find out the differences in cognitive function loss between right and left hemisphere ischemic stroke patients. Methods: This research is observational analytic study with retrospective cohort design performed in an Outpatient Neurology Clinic at RSUD Dr. Moewardi. There are 30 patients as subject consists of 14 right hemisphere and 16 left hemisphere ischemic stroke patients. Sampling techniques is exhaustive sampling. Cognitive function of patients with ischemic stroke was measured using Indonesian version of MoCA (Montreal Cognitive Assessment) questionnaires. The data collected are presented in tabular form and analyzed using the multiple linear regression analysis through SPSS 20.00 program for Windows. Results: The location of lesions influence cognitive function score significantly (p = 0,027) and there is a difference in which patients with left hemisphere lesion score lower cognitive function than patients with right hemisphere lesion with regression coefficient (? =-4.604). Age is a confounding variable on the relationship between lesion location with cognitive function. Age has negative effect on cognitive function, where the increase of age correlates with the declining cognitive function (p = 0.040; ? = 0.228-). Conclusions: The decline of cognitive function in left hemisphere ischemic stroke patients is more severe than right hemisphere ischemic stroke patients. Keywords: Cognitive Function Decline, Right Hemisphere Ischemic Stroke, Left Hemisphere Ischemic Stroke  
PENGARUH USIA TERHADAP CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) PADA WANITA DENGAN INFEKSI SALURAN REPRODUKSI BERBASIS PEMERIKSAAN PAPSMEAR Anggraini, Dewi Okta; Dirgahayu, Paramasari; Wasita, Brian
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Cervical Intraepithelial Neoplasia (CIN) is a dysplasia of cervical squamous cells posibbly turn into cervical cancer if not treated immediately. The established cause of CIN is Human Papillomavirus (HPV). Several studies showed correlation between Reproductive Tract Infection (RTI) with CIN. But, it is still controversial. Age is one of predicted factor which can influence CIN. Through some mechanisms, age can change the cervical cells. Methods: This study was cross-sectional approach. Samples were taken from medical record, papsmear?s form result and papsmear preparation in the Pathology Anatomy Laboratory, Faculty of Medicine, Sebelas Maret University from 2009-2012. Total of 410 samples were divided into two groups: control and case group. Control group contain sample without RTI while case group contain sample with RTI. Each group consisted of 205 women who subsequently divided into two subgroup, aged <40 years and ? 40 years. In this study, HPV infection is uncontrolled. Data were taken including name, age, clinical symptoms, ISR and CIN. These data are analyzed using Fisher test from SPSS version 19 for windows. Results: Total CIN were found: 5 samples (<40 years) and 3 samples (?40 years) from positive RTI; 20 samples (<40 years) and 53 samples (?40 years) from negative RTI. Fisher test results showed that age has correlation with CIN (p=0,001) and there is a significant difference risk between the age distribution with CIN [RD= -12.3%, 95%CI=(-19.8)-(-4798)]. In the negative RTI, there is a significant risk sample aged <40 years and aged ?40 years to get CIN [RD= -21.28%, 95% CI= (-33.91)- (-8.655)]. RTI does not have correlation with CIN (p = 0.06) Conclusion: Without HPV controlled, age distribution (<40 years and ?40 years) has an influence to the occurence of CIN and there is no correlation between RTI with CIN. Key words: Age, Cervical Intraepithelial Neoplasia (CIN), Reproduction Tract Infection (RTI)
HERBAL USAGE HISTORY AS A RISK FACTOR FOR DELAY IN TREATMENT ON BREAST CANCER PATIENTS IN SURAKARTA Hanum, Niluh Ayu Anissa; Yarso, Kristanto Yuli; Pesik, Riza Novierta
Nexus Kedokteran Klinik Vol 5, No 3 (2016): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Introduction: Breast cancer is a most commonly diagnosed cancer in women with an estimated 1.67 million cases diagnosed in 2012, i.e. 25% of all cancer cases. As many as 69% of breast cancer incidence was found to have reached stage III and IV, which has lower five-years survival rate. Various factors play a role in the delay of treatment, one of them is an herbal usage history. This study aims to determine whether an herbal usage history is a risk factor of delay in breast cancer patients in Surakarta. Methods: This study design was observational analytic with cross sectional approach. The samples were 45 breast cancer patients with delayed treatment and 55 breast cancer patients without delay treatment in RSUD Dr. Moewardi and RSU Kasih Ibu Surakarta. Samples were taken by fixed disease sampling, which then selected based on inclusion and exclusion criteria. The instrument used is the patient records and supplementary questionnaire. The variables studied were delays in treatment with an herbal usage history along with other confounding factors that may affect the delay of treatment. Data then analyzed using bivariate test and logistic regression. Results: The results of the bivariate analysis showed that an herbal usage history is a risk factor of delay in treatment, with p = 0.002 and OR = 3.69. While the results of the multivariate analysis showed that a low level of knowledge affect the most to delays in treatment of breast cancer with OR = 3.699. Conclusions:Herbal usage history was proved as a risk factor for delay in treatment on breast cancer patients in Surakarta. Keywords:Herbal Usage History, Delay in Treatment, Breast Cancer 
HUBUNGAN IBU HAMIL PEROKOK PASIF DENGAN KEJADIAN KETUBAN PECAH DINI Dithyana, Icha; Soetrisno, .; Dharmawan, Ruben
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Premature Rupture of Membranes (PROM) is most important issues commonly encountered. Premature rupture of membranes can cause some complications for both mother and fetus and may increase maternal morbidity and mortality. The prevalence of smoking in Indonesia increase every year and 85.4% current smokers smoke in the home where their family members live with them, thus threatening the health and safety of the environment. This research aimed to analyze the correlation between pregnant passive smoker and premature rupture of membrane. Methode : This research is observational analytic research using case control approach. Total of 60 samples were selected with a fixed - disease sampling, are all expectant mothers and maternity patients at the RSUD Dr. Moewardi. Data were collected by interview and medical record. The data which is got then analyzed by the program Statistic Products and Service Solution (SPSS) for Windows Release 17.0 with the use of statistic test Chi Square. Result: There is a significant correlation between pregnant passive smoker and premature rupture of membrane where the results obtained by using statistical test Chi Square is p = 0.02 and OR= 3.5. Conclusion: Pregnant passive smoker is 3.5 times more risky for experiencing premature rupture of membrane than non-passive smoker. Keywords: Pregnant passive smoker, Premature Rupture of Membrane (PROM) 
HUBUNGAN KUALITAS TIDUR DENGAN ANSIETAS PADA PENDERITA ASMA BRONKIALE Hapsari, Dhiandra Dwi; ., Harsini; ., Hartono
Nexus Kedokteran Klinik Vol 1, No 2 (2012): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Asthma is chronic inflammatory disease. Anxiety is psychiatric condition that is often found in many aspect of health one of which is asthma. Sleep disorders commonly found in patients with known asthma nocturnal. This study aimed to determine the relationship between sleep quality and anxiety of asthma patient. Methods: This study was observational by using cross-sectional design. The sample was selected by fixed exposure sampling from out patients who visited Pulmonology Clinics, RSUD Dr. Moewardi Surakarta.  This research was held on April - May 2012. The data was collected by interview and some datas taken from the medical records. The data was analyzed using Chi-Square model, run on Statistical Product and Service Solution (SPSS) 18.00 for Windows. Results: Samples sizes were 30 asthma patients with anxiety and 30 asthma patient without anxiety. The results of this study showed that there is difference of sleep quality between asthma patient with anxiety and without anxiety. Asthma patient who were anxiety had 0.13 times higher risk for experiencing poor sleep quality than those who were without anxiety (OR = 0.13; p < 0.05). Conclusions: There is relationship between the sleep quality with anxiety of asthma patient. It is a strong association and statistically significant. The higher the level of anxiety, the higher the risk for poor quality sleep. Keywords: Asthma bronchiale, anxiety, sleep quality. 
THE DIFFERENCES OF SCHIZOID PERSONALITY SCORE ON MEDICAL STUDENTS OF SEBELAS MARET UNIVERSITY YEARS 2013 WITH HIGH AND LOW EMOTIONAL QUOTIENT Zilmi, Ivonny Rembulan; Sudiyanto, Aris; Hanim, Diffah
Nexus Kedokteran Klinik Vol 4, No 2 (2015): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background : Emotional quotient is needed to control emotional changes during teenager. Teenager is also known with personality finding. Personality is a combination of emotional, attitudes, and behavior patterns of individuals. Some teenagers may have a personality disorder. Schizoid personality is one of the exsample of personality disorder. Someone with schizoid personality is tilted to be alone, over introspection, do not have best friend (only one friend) and do not want to have a relation like that and also not sensitive with rules or social habit. This research aims to see the differences of schizoid personality score on medical students of Sebelas Maret University years 2013 with emotional quotient high and low. Methods : This is an observational analytic research with case control studies approach. The research was done in Faculty of Medicine Sebelas Maret University Surakarta. Sample used are medical students years 2013 who are 18-21 years old. The sampling method used was purposive sampling after inclusive and exclusive selection based on research criteria. Dependent variable is schizoid personality, and independent variable is emotional quotient. Research subject completed (1) informed consent, (2) L-MMPI questionnaire, (3) emotional quotient questionnaire, (4) schizoid personality questionnaire. As much as 72 data were collected and analyzed using Mann Whitney. Result : There are 72 samples who 18 years old (30.6 %), 19 years old (53.8 %), 20 years old (11.1 %) and girls (68.1 %). Students with high emotional quotient have schizoid personality score lower, and vice verca. The averages of schizoid personality score on high emotional quotient is 62.19 and on low emotional quotient is 69.83 (p = 0.000). Conclusion : Statistically, there is a significant differences of schizoid personality score on medical students of Sebelas Maret University years 2013 with high and low emotional quotient. Keywords : schizoid personality, emotional quotient 
HUBUNGAN INDEKS MASSA TUBUH (IMT) DENGAN DERAJAT KEPARAHAN STROKE ISKEMIK PADA PASIEN DI UNIT PENYAKIT SARAF RSUD DR. MOEWARDI Suganda, Aga; Suroto, .; Utari, Siti
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Stroke is the third leading cause of death in the world. Approximately 80% of strokes are ischemic strokes. One of the significant prognostic factors causing morbidity of stroke patients is the Body Mass Index (BMI). National Institutes of Health Stroke Scale (NIHSS) is a systematic examination to determine the severity stroke. The aim of this study is to determine the relationship of body mass index (BMI) with ischemic stroke severity in patients at Neurology Ward Dr. Moewardi Hospital. Methods: This was an observational study with cross sectional analytic. A total of 32 subjects were selected by purposive sampling, they were ischemic stroke patients in the Neurology Ward Dr. Moewardi Hospital. Data were collected by direct interview, direct measurement of weight and height also examination of severity stroke patient by using NIHSS score. Data analysis used multiple logistic regression models and were processed with Statistical Product and Service Solutions (SPSS) 17.00 for Windows. Results: Multiple logistic regression showed OR = 17,690; CI 95% 1,190 ? 263,039; and p = 0,037. These results have been earned by controlled the confounding variables of age, blood pressure, blood sugar levels, cholesterol levels and smoking history. Conclusions: Ischemic stroke patients with high BMI score has risk of ischemic stroke severity 17.690 times higher than whose normal BMI score.There is a strong relationship between body mass index (BMI) with the severity of ischemic stroke patients at Neurology Ward of Dr. Moewardi Hospital, the relationship is statistically significant in this study. Keywords:BMI, Stroke Severity, Ischemic Stroke
HUBUNGAN HIPERGLIKEMIA DENGAN KEJADIAN STROKE HEMORAGIK PADA PEMERIKSAAN MULTISLICE CT-SCAN KEPALA TANPA KONTRAS DI RSUD DR. MOEWARDI SURAKARTA Christyan, Fernando Feliz; Widiastuti, .; Subandono, Jarot
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Stroke is the third most common cause of death in the world, with a high prevalence of death in low-and middle-income countries. Hyperglycemia has been associated with atherosclerotic lession resulting in cerebral aneurysm which can lead to hemorrhagic stroke. CT-Scan is considered sufficiently sensitive for detecting acute hemorrhage, as well as detecting mass lessions. The aim of this study was to determine the correlation between hyperglycemia and hemorrhagic stroke incident on noncontrast multislice CT-Scan of the head examination. Methods: This study was an observational study with the analytical approach to the subject of cross-sectional study. 70 subjects were selected by fixed- disease sampling methods. These subjects have been performed a noncontrast multislice CT-Scan of the head examination. Data was collected by reading the result of blood glucose level and CT-Scan of the head examination on patient?s medical record. Data were processed with Statistical Product and Service Solution (SPSS) 17.00 for Windows Results: Chi-Square models showed that X2 = 7,19 with 5% significancy. OR (Odds Ratio) in hemorrhagic stroke was 4,26 (CI 95% = 1,43-12,74). Patient with hyperglycemia increases the risk of getting hemorrhagic stroke  4,26 (4) times than patient without hyperglycemia. Conclusion: There is a correlation between hyperglycemia and hemorrhagic stroke incident. Keywords: hyperglycemia, hemorrhagic stroke, noncontrast head CT-Scan  
HUBUNGAN ENDOMETRIOSIS DENGAN INFERTILITAS PADA PASIEN POLIKLINIK OBSTETRI GINEKOLOGI DAN KLINIK FERTILITAS SEKAR RSUD DR. MOEWARDI SURAKARTA Shabrina, Irsalina Nur; Oepomo, Tedja Danudjo; ., Yulia Sari
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Women with endometriosis have a difficult pregnancy. Nowadays, infertility becoming a difficult problem towards married persons, especially for the wife,  from this research would known the fact is it true that endometriosis is a disease that is often found in infertil woman. This study aims is to determine the relationship between endometriosis and infertility among the patients at RSUD Dr. Moewardi Surakarta. Methods: This study was an observational analytic studies, with case-control approach. Data were taken from female patients who had been hospitalized on the Obstetrics Gynecology Clinic and Sekar Fertility Clinic of RSUD Dr. Moewardi from January 2012 to July 2013, interviews were conducted with a questionnaire to find out the history of parity. Data were analyzed by chi-square statistical test (? = 0.05). Results: Based on the research towards 44 sampels, consisted of 22 samples of cases and  22 samples of controls were identified that there were 16 infertile women with endometriosis, 2 fertile women who have endometriosis, 6 infertile women without endometriosis, and 20 fertile women without endometriosis. Chi Square statistical test results showed a significant relationship between endometriosis with infertility with p = 0.00 (p <0.05). Conclusions: There is a statistically significant relationship between endometriosis with infertility (p = 0.00) among the patients of RSUD Dr. Moewardi Surakarta. Keywords: endometriosis, infertility  
HUBUNGAN INDEKS MASSA TUBUH OVERWEIGHT DENGAN GAMBARAN FATTY LIVER PADA USG ABDOMEN DI RSUD DR. MOEWARDI Dewi, Charismatika Syintia
Nexus Kedokteran Klinik Vol 1, No 2 (2012): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Overweight increasing in the world is one result of the modernization of lifestyles, the increasing caloric intake and limited physical activity. Overweight is more realized to become of a person's risk for metabolism chronic disease. Fatty liver is increasingly recognized condition that also develop into chronic liver disease. This study aims to examine the relationship between overweight body mass index and fatty liver picture on USG Abdomen in RSUD dr. Moewardi. The study is expected to assist in diagnosis and treatment is more adequate and the prevention of fatty liver early on. Methods: This research is an analytical observational research with cross-sectional approach. Subjects were patients undergoing abdominal ultrasound Radiology Installation in RSUD dr. Moewardi in June 2012. Sampling was done after a fixed exposure sampling were selected based on inclusion and exclusion criteria of the sample. The obtained data were as many as 40 samples, taken immediately to see the results of focused abdominal ultrasound examination of heart and with a body mass index calculation derived from measurements of height and weight. Then samples were analyzed by Chi Square test and Odds Ratio test using the Statistical Product and Service Solution (SPSS ) 17.0 for Windows. Result: The data link overweight with a body mass index picture of fatty liver on abdominal ultrasound in RSUD dr. Moewardi was tested by Chi Square test bivariate analysis, obtained p = 0,011. Odds Ratio test was then performed to determine the strength of a causal relationship with OR = 5,571. Conclusion: There is a significant association between overweight body mass index with images of fatty liver on abdominal ultrasound (p = 0,011), where an overweight have a risk for developing fatty liver 5,571 times that of a normoweight or underweight. Keywords: fatty liver, body mass index, overweight, ultrasound 

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