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Nexus Kedokteran Klinik
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Articles 20 Documents
Search results for , issue " Vol 2, No 1 (2013): Nexus Kedokteran Klinik" : 20 Documents clear
Hubungan Jenis Kelamin dengan Gangguan Kognitif Pasca Stroke Iskemik Serangan Pertama dengan Lesi Hemisfer Kiri Prasetyo, Bagus Dwi; Suroto, .; Mirawati, Diah Kurnia
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Stroke is a cerebrovascular disease which until now the third leading cause of death in the world. Stroke can cause physical disability to psychosocial disfunction, such as cognitive impairment. This study aimed to analyze the relationship between gender and cognitive impairment after ischemic stroke first attack with left hemisphere lesions. Methods: This type of research is an observational analytic with cross-sectional approach. Sample of this study were post ischemic stroke  patients with a total sample of 60 people. Measuring instrument used was Mini Mental State Examination (MMSE), and performed data analysis with multiple logistic regression analysis. Results: After the study on a sample of 60 post-stroke patients with a first ischemic attack left hemisphere lesions found post-stroke cognitive impairment in male patients amounted to 46.7%, whereas in female patients by 30%. The results of calculations using Binary Logistic Regression Analysis obtained OR = 0.14; CI 95% 0025 to 0794 and p = 0026. From these data showed statistically significant relationship between the gender with cognitive impairment after ischemic stroke first attack with left hemisphere lesions. Conclusions: There is a statistically significant relationship between gender to cognitive impairment on post-ischemic stroke patients. This conclusion is drawn after controlling for the effects of confounding factors such as age, level of education and cardiovascular risk factors: diabetes mellitus, hypertension, dyslipidemia. Keywords: gender, cognitive impairment, ischemic stroke
Comparison of Effect between Inhalative Anesthetics with Isoflurane and Sevoflurane on Oxygen Saturation Setiawan, Prabuwinoto; Sudjito, M.H.; Probandari, Ari
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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ABSTRACT   Background: Inhalative anesthesia with isoflurane and sevoflurane are known to lower the oxygen saturation in patients. Both of these agents reduce the ventilation response to hypoxia. This study aimed to compare the effect of giving inhaled anesthetics isoflurane and sevoflurane to changes in oxygen saturation. Methods: This study was an observational analytic study with cross-sectional approach. The study was conducted at the Central Installation of Surgery dr. Moewardi Hospital. Samples were taken by consecutive sampling. There were two groups in this study, the group that received isoflurane anesthesia and sevoflurane anesthesia. Each group was observed for the changes in oxygen saturation during the operation using the bed side monitor. The data which have been collected then be analyzed using the Mann Whitney test and Pearson correlation test. Results: These results revealed that in both groups, isoflurane and sevoflurane, there was a decrease in oxygen saturation in the induction phase (sevoflurane = 97.42 ± 0.90; isoflurane = 97.00 ± 0.75; p = 0.113). However, after the induction phase the oxygen saturation among the patients of the isoflurane group was more fluctuating than the ones of the sevoflurane group (p intubation = 0.001; p incision 5’ = 0.117; p incision 10’ = 0.001; p incision 15’ = 0.048). The further analysis showed no statistically significant difference in oxygen saturation between the isoflurane and the sevoflurane groups (p = 0.113). Conclusions: There are no significant differences in changes of oxygen saturation between the isoflurane and sevoflurane anesthesia on the induction phase, 5 minutes after incision and 15 minutes after incision. Anesthesia with sevoflurane in oxygen saturation is more stable compared with isoflurane anesthesia on intubation phase up to 15 minutes after incision. Keywords: inhalation anesthesia, sevoflurane, isoflurane, hemodynamic, oxygen saturation
Faktor-Faktor Risiko Terjadinya Epilepsi pada Anak di RSUD Dr. Moewardi Riski Setianingsih, Paramita; Soedomo, Agus; Giri Moelyo, Annang
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: There is no definite epidemiological data about the number of patients with epilepsy in Indonesia. It is estimated that there are 900.000–1.800.000 epilepsy patients. The onset can be at any age, in which 30–32.9% patients experience the first convulsion less than 4 years old, 50-51.5% in less than 10 years old, 75–83.5% in less than 20 years old, 15% in more than 25 years old  and 2% in more than 50 years old. Several risk factors cause epilepsy in children e.g. hereditary factor, asphyxia, premature, complex febrile seizure and head trauma. Methods: This was a case control study. Subject were selected consecutively from epilepsy children in Dr. Moewardi Hospital and matched with pediatric patients in Outpatlient Pediatric Clinics. The data was collected by structured interview and medical record. The data analyzed by Chi-Square test and Logistic Regression. All statistic analysis was measured by Statistical Product and Service Solution (SPSS) 16.00 for Windows. Results: There are 84 subjects eligible for the criteria. Asphyxia (p= 0.121) and premature (p= 0.393) are not risk factor for epilepsy. Hereditary factor (p= 0.001), complex febrile seizure (p= 0.000), and head trauma history (p= 0.001) are significant risk factor for epilepsy. Logistic regression result shows that the risk factors affecting epilepsy in children at Dr. Moewardi Hospital were complex febrile seizure (OR= 18.267 ; Cl 95% 5.393 s.d. 61.873 ; p= 0.000) and head trauma history (OR= 16.341 ; Cl 95% 3.346 s.d. 79.801 ;  p= 0.001). Conclusions: Risk factor of epilepsy in children are complex febrile seizure and head trauma history. Keywords: hereditary, asphyxia, premature, complex febrile seizure, head trauma history, children with epilepsy  
The association between pregnancy spacing and iron deficiency anemia at RSUD Dr. Moewardi Damayanti, Puspa; Sunaryo, Rustam; Murti, Bhisma
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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ABSTRACT Background: Pregnant women to be one of those most vulnerable to malnutrition, especially iron deficiency anemia and iron deficiency anemia coping is currently focused on the tablet of iron (Fe) in pregnant women. While pregnancy distance of less than 2 years old are at greatest risk for iron deficiency anemia. Methods: This analytic study was observational using case-control approach. A sample of 60 study subjects was selected by purposive sampling and fixed disease sampling from outpatients who visited Obstetric Clinics, RSUD Dr. Moewardi Surakarta. The data was collected by interview and some datas taken from the medical records. The data was analyzed using multiple logistic regression model on SPSS 20 for windows. Results : The pregnant women with pregnancy spacing ≥ 24 months at RSUD Dr. Moewardi have a greater risk for iron deficiency anemia 0,8 times larger than <24 months pregnancy spacing (OR=0,8 ; Cl 95% 0,17 s.d. 3,80; p=0,778). This analysis have control gestational age as a confounding factor, but not control the intake of nutrient. Conclusion: There is a weak and negative association, and not statistically significant between the gestational age with iron deficiency anemia.. Keywords: pregnancy spacing, iron deficiency anemia
Hubungan Frekuensi Bangkitan dengan Skor Kualitas Hidup pada Penderita Epilepsi Umum di RSUD Dr. Moewardi Dewayani, Fillisita Chandramalina; Mirawati, Diah Kurnia; Sulaeman, Endang Sutisna
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Epilepsy is a chronic neurology disease. When epilepsy was not well-controlled, it could cause so many effects such as decreasing quality of life score. The aim of this study was to find out the relation between seizure frequency and quality of life score of general epileptic patients in Dr. Moewardi hospital. Methods: This was an observational study with analytic cross-sectional approach conducted from July to August 2012 at Neurology Department of Dr. Moewardi hospital. Samples were taken by purposive sampling after selected based on inclusion and exclusion criteria. The frequency of seizure was recorded by medical record. The quality of life was assessed by QOLIE-31 questionnaire. Score of seizure frequency and quality of life were analyzed with one-way ANOVA models by SPSS 17.0 for Windows. Results: There were 30 samples consist of 13 women and 17 men. The average of quality of life total score in high seizure frequency was 59.56 ± 4.71, medium seizure frequency was 78.32 ± 2.20, and seizure free was 83.40 ± 2.34. There was a negative relationship between seizure frequency and quality of life score on patients with general epilepsy. Analysis by one-way ANOVA/Kruskal Wallis showed a statistically significant relationship (p < 0.05) for total score component and the other seven components. Conclusion: Patients with higher seizure frequency had lower quality of life score. Keywords: seizure frequency, quality of  life score, general epilepsy  
Hubungan antara Kecemasan dengan Frekuensi Bangkitan pada Penderita Epilepsi Parsial di RSUD Dr. Moewardi Anggraeni, Lucia Pancani; Mirawati, Diah Kurnia; Sulaeman, Endang Sutisna
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background : Anxiety is a psychological disorder that involves dysregulation of the nervous system Therefore, anxiety could affected seizure’s threshold in people with epilepsy indirectly. The aim of this study was to know an association between anxiety and seizure frequency of partial epileptic patients in hospitals Dr. Moewardi. Methods: This was an observational study with analytic cross sectional approach. Samples were taken by purposive sampling after selected based on inclusion and exclusion criteria. The data were obtained by using of TMAS anxiety scale, interviewed seizures frequency in last one month, and the patients medical record. Analysis of anxiety and seizures frequency’s score used linear regression models by SPSS 17.0 for windows Results: There were 31 samples consisted of 10 women and 21 men. Result showed a significant positive relation between anxiety and seizure frequency of partial epileptic patients in hospitals Dr. Moewardi (p < 0.05, CI 95% = 0.06 - 0.037). Linear regression analysis test showed an equation that Y= a + bX = -1.174 + 0.218 X. It meaned that the seizure frequency would rise  -1.174 + 0.218 X unit for every inrcreasing of anxiety level. Conclusion: Patients with higher level of anxiety have had more often seizure attack. Keywords: Partial epileptic patients, anxiety, frequency of seizure 
Pengaruh Kelainan Refraksi terhadap Terjadinya Vertigo pada Pasien di Poli Mata RSUD Dr. Moewardi Prawitasari, Fitri; Suratno, .; Indrakila, Senyum
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Refractive error occurs when the lights do not fall exactly at retina and cause blur vision. Visual system disorder causes balance disorder with vertigo symptom. This research aims to know the effect of refractive error on vertigo to patients at Ophthalmology Department of Dr. Moewardi Hospital. Methods: This research was observational-analitic with cross-sectional approach. The samples for this research were the patients at Ophthalmology Department of Dr. Moewardi Hospital aged 18-58 years old who has refractive error such as miopia, hipermetropia, or astigmatism while the second group (control) were people  aged 18-58 years old without refractive error. Those samples were given questionnaire Vertigo Symptom Scale-Short Form and were tested for the balance to find out vertigo. Data was analyzed with Fisher Exact Test. Results: After the research to 25 patients with refractive error, 6 of 25 patients had vertigo. The second group, samples without refractive error had no vertigo. The result of Fisher Exact Test showed p value= 0,022 (p<0,05). Conclusions: There was effect of refractive error on vertigo to patients at Ophthalmology Department of Dr. Moewardi Hospital. Keywords: Refractive error, vertigo 
Hubungan Gagal Ginjal Kronik dengan Tebal Parenkim Ginjal pada Pemeriksaan USG Abdomen Fokus Ginjal Alfiani, Nur; Suyono, .; Balgis, .
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Complication that often occurs in chronic renal failure is the reduction of the kidney size. It widely associates with the thinning of the renal cortex due to pathological process. Unlike the cortex, the pathological process which occurred in renal medulla in chronic renal failure has not fully understood yet. Not many studies have examined the association of chronic renal failure with renal parenchyma overall. Therefore, this study aimed to determine the relationship of chronic renal failure with renal parenchyma width on abdomen USG renal focus. Method: This study was an analytical observational research with cross-sectional approach. Sample were taken using fixed-exposure sampling. Sample consisted of 30 subjects were divided into two groups, chronic renal failure and non chronic renal failure. Samples were then measured for renal parenchyma width using abdomen USG renal focus. The data were analyzed with independent-sample t test. In addition, to control confounding factor that could affect renal parenchyma width, age was selected to be controlled using multiple linear regression analysis. All of the data were analyzed using SPSS 17.0 for windows. Result: Patients with chronic renal failure had renal parenchyma width 7.92±2.57 mm (p = 0.001), while patients non chronic renal failure had renal parenchyma width 15.64±1.85 mm ( p = 0.001). Furthermore, based on the calculation, the multiple linear regression analysis showed the model equation Y = 16.78 – 7.95 X1 – 1.72 X2. The coefficient of determination (R2) of the regression analysis obtained a value of 0.781 means that 78.1% variation in the parenchyma width (Y) can be explained by variations contained in the chronic renal failure (X1) and age ≥54 years old (X2), while 21.9% is explained by other variables not included in the model equations. Conclusion: This study reveals that there is significant correlation between chronic renal failure and renal parenchyma width (p < 0.05), where chronic renal failure patients have renal parenchyma width thinner than the non chronic renal failure patients. Keywords: Chronic Renal Failure, Renal Parenchyma Width, Age, abdomen USG 
Hubungan antara Hipoglikemi dengan Kejadian Hipotermi pada Neonatus Rujukan di RSUD Dr. Moewardi Virgiansari, Dio Dara; Hidayah, Dwi; Saptawati, Leli
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Neonatal hypoglycaemia is an avoidable cause of mortality and neurodevelopmental impairment. Hypoglicemia may develop to hypothermia as a result of metabolic thermogenesis disturbance. Hypothermia during the newborns period is widely regarded as a major contributory cause of significant morbidity and mortality in developing countries including Indonesia, about 7% prevalence of hypothermia has been reported happens on newborns.  The objective of this study was to determine the association between hypoglicemia and hypotermia in newborns. An analytic observational using cross sectional approach was used in this study. A total of eighty one newborns was selected by fixed-disease sampling. Sample of this study were the newborns who referred to Dr. Moewardi Hospital. The data were collected by the measurement of blood glucose concentration and axillary temperature of newborns. The data was analyzed using multiple logistic regression test on SPSS 16 for Windows. Hypoglycemic newborns have a risk of hypothermia 2.381 times higher than non hypoglicemic newborns after controlling some confounding factors, such as: age, birth weight, gestational age, and status of asphyxia, altough it was statistically not significant (OR = 1.98; CI = 95%; 0.54, 7.73; p = 0.305). Early neonatal age (0-7 days), low birth weight (< 2.500 gram), early gestational age (< 37 weeks), asphyxia status were also risk factors of hypothermia in newborns. There was a moderate association between hypoglicemia and hypothermia on referral newborns, altough it was statistically not significant. Hypoglycemic newborns have a higher risk of hypothermia than non hypoglicemic newborns after controlling some confounding factors, such as: age, birth weight, gestational age, and status of asphyxia. Keywords: newborns, referral, hypoglicemia, hypothermia
Efek Anestesi Inhalasi Sevofluran dan Isofluran Terhadap Frekuensi Nadi Fatimah, Aulia Nurul; Sudjito, Mulyo Hadi; Probandari, Ari
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Anesthesia is an important part of the surgery. Sevoflurane and isoflurane are two inhalation anesthesia drugs have been commonly used. During anesthesia, one of indicators should be monitored is frequency of pulse. This research aimed to know the effects of these two drugs to the frequency of pulse. Methods: This research was an analytical observational research with the approach of cross sectional. The sample was taken by consecutive sampling after being selected based on the inclusion and exclusion criteria. Totally, 50 patients were divided into two groups of inhalation anesthetic sevoflurane and inhalation anesthetic sevoflurane and isoflurane. Data was analyzed with independent t test. Results: The p values on t-independent test in the early phase of the pulse frequency, phase induction and phase intubation were 0.04; 0.00; 0.02, and of the phase 5’ of incision, 10’of incision and 15’of incision were 0.02; 0,0; 0.03. This results showed statistical significant of mean of pulse-frequency difference between sevoflurane and isoflurane in each of phase of inhalation anesthesia. Conclusions: Both sevoflurane and isoflurane influence the frequency of pulse. The mean of pulse frequency by isoflurane is higher than sevoflurane. However, inhalation anesthesia sevoflurane provides better stability than isoflurane. Keywords: Anesthetic Inhalation, Frequency of Pulse, Isoflurane, Sevoflurane

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