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Nexus Kedokteran Klinik
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Search results for , issue "Vol 2, No 3 (2013): Nexus Kedokteran Klinik" : 40 Documents clear
HUBUNGAN INDEKS MASSA TUBUH (IMT) DENGAN DERAJAT KEPARAHAN STROKE ISKEMIK PADA PASIEN DI UNIT PENYAKIT SARAF RSUD DR. MOEWARDI Suganda, Aga; Suroto, .; Utari, Siti
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Stroke is the third leading cause of death in the world. Approximately 80% of strokes are ischemic strokes. One of the significant prognostic factors causing morbidity of stroke patients is the Body Mass Index (BMI). National Institutes of Health Stroke Scale (NIHSS) is a systematic examination to determine the severity stroke. The aim of this study is to determine the relationship of body mass index (BMI) with ischemic stroke severity in patients at Neurology Ward Dr. Moewardi Hospital. Methods: This was an observational study with cross sectional analytic. A total of 32 subjects were selected by purposive sampling, they were ischemic stroke patients in the Neurology Ward Dr. Moewardi Hospital. Data were collected by direct interview, direct measurement of weight and height also examination of severity stroke patient by using NIHSS score. Data analysis used multiple logistic regression models and were processed with Statistical Product and Service Solutions (SPSS) 17.00 for Windows. Results: Multiple logistic regression showed OR = 17,690; CI 95% 1,190 ? 263,039; and p = 0,037. These results have been earned by controlled the confounding variables of age, blood pressure, blood sugar levels, cholesterol levels and smoking history. Conclusions: Ischemic stroke patients with high BMI score has risk of ischemic stroke severity 17.690 times higher than whose normal BMI score.There is a strong relationship between body mass index (BMI) with the severity of ischemic stroke patients at Neurology Ward of Dr. Moewardi Hospital, the relationship is statistically significant in this study. Keywords:BMI, Stroke Severity, Ischemic Stroke
PERBEDAAN PEMBERIAN ASAM VALPROAT DAN FENOBARBITAL TERHADAP KADAR KALSIUM DARAH PASIEN EPILEPSI ANAK DI RSUD DR. MOEWARDI Kusumaningtyas, Friska; Tia Nur, Fadhilah; Ratna Budiani, Dyah
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Antiepileptic drugs have different mechanisms. Meanwhile valproate acid and phenobarbital have similar mechanism, inactivation of voltage gated Ca2+ channels, Na+ channels, and increased activity of GABAergic inhibitory. However, the mechanism of phenobarbital also induces cytochrome P450 (CYP450) enzymes that affect the metabolism of vitamin D. The aim of this study was to examine the differences between valproic acid and phenobarbital on blood calcium levels of pediatric epilepsy. Methods : The cross sectional study was conducted by 24 pediatric epilepsy in the pediatric neurology clinic of RSUD Dr. Moewardi who met the inclusion criteria. Calcium ion levels in blood serum obtained from the medical records of pediatric patients who had been done routine laboratory tests about the side effects of antiepileptic drugs. Data normality was tested by Shapiro-Wilk. The differences of giving valproic acid and phenobarbital on calcium ion level of blood serum were analyzed by the Mann-Whitney test. The correlation between long term drug use and calcium ion levels in blood serum were analyzed by Spearman test. Results : The analysis results show that there is no difference between calcium ion levels in  blood serum of valproic acid and phenobarbital of pediatric epilepsy in RSUD Dr. Moewardi with p = 0.881 (p > 0.05). Correlation analyze show that there is no correlation between duration of drug intake and calcium ion levels in blood serum levels with p = 0.191 (p > 0.05), 35.7% of subjects had a negative correlation for valproic acid and p = 0.548 (p > 0.05), 23.2% of subjects had a negative correlation for phenobarbital. Conclusion : There is no significant difference between calcium ion levels in blood serum of valproic acid and phenobarbital in pediatric epilepsy in RSUD Dr. Moewardi. As well as, there is a weak correlation between duration of drug intake and calcium ion in blood serum. Keywords : epilepsy, antiepileptic drug, valproic acid, phenobarbital, calcium ion 
HUBUNGAN MEROKOK DENGAN KONVERSI SPUTUM PENDERITA TB PARU KASUS BARU DI RSUD DR. MOEWARDI SURAKARTA Yonisa, Zefania; Harsini, .; Primadewi, Novi
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Tuberculosis or TB is an infectious disease caused by Mycobacterium tuberculosis complex and still a major health problem in Indonesia. Smoking TB patients have a greater risk for treatment failure and persistent infection. This study aims to determine the relationship between smoking and sputum conversion among patients with new cases pulmonary tuberculosis in Dr. Moewardi Hospital, Surakarta. Methods:This study was an observational analytic cross sectional approach. Subjects were new cases of pulmonary TB patients who have completed the intensive phase of treatment in Dr. Moewardi Hospital from January 2010 until March 2013. Patients with new cases pulmonary TB interviewed with a questionnaire to determine their smoking history. Sputum examination results seen in TB Treatment Card 01. Results were analyzed by Chi-Square statistical test (? = 0.05). Results: Of the 49 samples, a total of 26 pulmonary TB patients were smokers and 23 samples of patients with pulmonary tuberculosis are not categorized as smokers. Sputum conversion occurs more frequently in non-smoking pulmonary TB patients than smokers with pulmonary TB. Chi Square statistical test results showed a significant relationship between smoking and sputum conversion among patients with new cases pulmonary TB with p = 0.03 (p <0.05). Conclusions: There is astatistically significant association between smoking and sputum conversion among patients with new cases pulmonary TB. Smoking has a risk that sputum conversion does not occur after 2 months intensive phase of TB treatment. Keywords: smoking, sputum convertion, pulmonary tuberculosis 
HUBUNGAN ANTARA PENGGUNAAN OBAT NYAMUK DENGAN TINGKAT KONTROL ASMA Astuti, Astari Rindu; Aphridasari, Jatu; Widardo, .
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Asthma is a chronic inflammatory disorder of the airways with episodic symptoms such as cough, shortness of breath, wheezing, and uplifted chest. Mosquito repellent consists of chemical synthetic chemical materials that can prevent mosquito?s bite towards. This study is to find out if there is or not any correlation between mosquito repellent usage and rate of asthma control. Methods: This study was an analytic observational study using cross sectional approach conducted on May to July 2013. Sixty samples were taken by using purposive sampling from outpatients who visited Pulmonary Clinics of Local Public Hospital Dr. Moewardi and fulfilled the inclusive criteria. The data was collected via interview by using a set of questionnaire. The data was then analyzed using Chi-Square test on Statistical Product and Service Solution (SPSS) 20.00 for Windows. Results: There is no significant correlation between mosquito repellent usage and rate of asthma control. From the Chi-Square test result, it was obtained that the significance value is p = 0,817. Conclusions: Based on this research, it can be concluded that there is no correlation between mosquito repellent usage and rate of asthma control. Keywords: mosquito repellent, rate of asthma control  
Perbedaan Ankle Brachial Index (ABI) pada Pasien Diabetes Melitus Tipe 2 Obese dan Normal Weight di RSUD Dr. Moewardi Miranti, Biltinova Arum; Sugiarto, .; Widardo, .
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Peripheral Arterial Disease (PAD) is one of the complications of type 2 diabetes mellitus. Obesity is a risk factor of PAD and it is estimated 80 - 90% of patients with type 2 diabetes mellitus are overweight or obese. ABI is a simple method for diagnosing PAD and the ABI value of &lt; 0.9 means that the patient suffers PAD. The aims of this study are to know the difference of ABI between obese and normal weight patients with type 2 diabetes mellitus in Dr. Moewardi Hospital and the correlation between ABI and the Body Mass Index (BMI). Methods: This study is an analytical observation by means of cross sectional approach. The subjects were patients of Dr. Moewardi Hospital registered from April to July 2013, suffering type 2 diabetes mellitus. Subjects were selected through purposive sampling. The data were obtained by measuring the patients’ BMI, examining the patients’ ABI and checking the patients’ medical record. The data were analyzed by the unpaired t test, significant if p value &lt; 0.05, and by Spearman correlation test through SPSS 20.0 Statistic program for Windows. Results: Data were taken from 33 subjects consisting of 11 obese patients and 22 normal weight patients suffering type 2 diabetes mellitus. The result obtained shows that 9 patients were included in the borderline category of ABI values, 6 (66.7%) patients were obese and 3 (33.3%) patients had normal weight. The unpaired t test shows that the mean of ABI of obese vs normal weight patients with type 2 diabetes mellitus is 0.98 ± 0.06 vs 1.01 ± 0.06, p = 0.221. The Spearman correlation test between ABI and BMI shows p = 0.028 and r = -0.384. Conclusions: The study suggested that there is no significant difference mean of ABI between obese and normal weight patients with type 2 diabetes mellitus in Dr. Moewardi Hospital. However, based on the interpretation of ABI values ​​obtained, the percentage of subjects with lower ABI values ​​was found greater in obese patients with type 2 diabetes mellitus (66.7%). There is correlation between ABI and BMI. Keywords: ABI, obese type 2 diabetes mellitus, normal weight type 2 diabetes mellitus  
Hubungan Merokok dengan Konversi Sputum Penderita TB Paru Kasus Baru di RSUD Dr. Moewardi Surakarta Yonisa, Zefania; Harsini, .; Primadewi, Novi
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Tuberculosis or TB is an infectious disease caused by Mycobacterium tuberculosis complex and still a major health problem in Indonesia. Smoking TB patients have a greater risk for treatment failure and persistent infection. This study aims to determine the relationship between smoking and sputum conversion among patients with new cases pulmonary tuberculosis in Dr. Moewardi Hospital, Surakarta. Methods:This study was an observational analytic cross sectional approach. Subjects were new cases of pulmonary TB patients who have completed the intensive phase of treatment in Dr. Moewardi Hospital from January 2010 until March 2013. Patients with new cases pulmonary TB interviewed with a questionnaire to determine their smoking history. Sputum examination results seen in TB Treatment Card 01. Results were analyzed by Chi-Square statistical test (α = 0.05). Results: Of the 49 samples, a total of 26 pulmonary TB patients were smokers and 23 samples of patients with pulmonary tuberculosis are not categorized as smokers. Sputum conversion occurs more frequently in non-smoking pulmonary TB patients than smokers with pulmonary TB. Chi Square statistical test results showed a significant relationship between smoking and sputum conversion among patients with new cases pulmonary TB with p = 0.03 (p &lt;0.05). Conclusions: There is astatistically significant association between smoking and sputum conversion among patients with new cases pulmonary TB. Smoking has a risk that sputum conversion does not occur after 2 months intensive phase of TB treatment. Keywords: smoking, sputum convertion, pulmonary tuberculosis 
Hubungan Ibu Perokok Pasif Selama Kehamilan Dengan Kejadian Infeksi Respiratori Akut Bagian Bawah Windriya, BRA I Ratu; Andarini, Ismiranti; Sahir, Endang
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Acute Respiratory Infection (ARI) has been the main cause of child morbidity and mortality, includes upper ARI and lower ARI. Lower respiratory infection is the infection under of larynx, includes epiglotitis, croup (laryngotracheobronchitis), bronchitis, bronchiolitis, and pneumonia. The one risk factor of lower ARI is air pollution (if in the house use firewood to cook and/or cohabit with active smoker). Prenatal exposure to cigarette smoke will affect the morphogenesis of fetus lung so it will increase respiratory infection risk after the fetus is born. This research aims to find out how big the relationship between maternal passive smoking during pregnancy with lower acute respiratory infection. Methods: The research was an analytical survey with case control approach implemented in March-April 2013 in RSUD Dr. Moewardi Surakarta. The samples was taken using purposive sampling and the number of samples based on rule of thumb. Dependent variable in this research was lower acute respiratory infection and independent variable was maternal passive smoking during pregnancy. The parents of the sample signed informed consent as the consent form and filled the questionnaire. Medical records was required for obtained the data about diagnose and nutrition status of the samples. This research were obtained 60 samples and analyzed use bivariate analysis continued multivariate analysis with logistic regression test. Results: The research with bivariate analysis showed that maternal passive smoking during pregnancy and low birth weight infant were significant with p &lt; 0.05. Crude OR maternal passive smoking during pregnancy was 5.688. By multivariate analysis with logistic regression test obtained adjusted OR = 4.000, p = 0.043 (p &lt; 0.05), and 95% CI = 1.043-15.343 for independent variable maternal passive smoking during pregnancy. Conclusions: There was significant relationship between maternal passive smoking during pregnancy with lower acute respiratory infection of child (p = 0.043), at the risk of 4.000 times more likely to suffer lower ARI. Keywords: Pregnant Maternal, Passive Smoking, Lower Acute Respiratory Infection 
Hubungan antara Kadar Hematokrit dengan Derajat Keparahan Stroke Iskemik Fase Akut pada Pasien di Unit Penyakit Saraf RSUD Dr. Moewardi Hidayat, Agung Wahyu; Suroto, .; Utari, Siti
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Stroke is the main cause of morbidities and  the third leading cause of death in the world, also promote the functional disorder of the patient. The increase of hematocrit level is one of  risk factor the occurrence of ischemic stroke, by increasing the viscosity and decreasing blood perfusion to the brain. National Institute of Health Stroke Scale (NIHSS) is a parameter used to measure the severity of acute ischemic stroke. This study was proposed to know correlation between hematocrit levels and severity of acute ischemic stroke patients in neurolog ward Dr. Moewardi Hospital. Methods: This was an observational study with cross sectional analytic approach. A total of 44 subjects were selected by purposive sampling, they were acute ischemic stroke patients in neurology ward Dr. Moewardi Hospital. Data were collected by direct interview, examined the patients with NIHSS score and from medical record to got the value of hematocrit. Data analysis used multiple logistic regression models and were processed with Statistical Product and Service Solutions(SPSS) 17.00 forWindows. Results: This study showed a positive correlation and statistically significant between hematocrit levels and severity of acute ischemic stroke patients (r = 0,408; p &lt; 0,009) with moderate correlation strength. Multiple logistic regression analysis showed OR = 8,086; CI 95% 1,108 – 59,005; and p = 0,039. Confounding factor, e.g smoking, and blood sugar have been controlled. Conclusions: There is moderate correlation between hematocrit levels and severity of acute ischemic stroke  patients in neurology ward Dr. Moewardi Hospital. Keywords:Hematocrit levels, Severity of acute ischemic stroke, NIHSS  
Hubungan Indeks Massa Tubuh (IMT) dengan Derajat Keparahan Stroke Iskemik pada Pasien di Unit Penyakit Saraf RSUD Dr. Moewardi Suganda, Aga; Suroto, .; Utari, Siti
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Stroke is the third leading cause of death in the world. Approximately 80% of strokes are ischemic strokes. One of the significant prognostic factors causing morbidity of stroke patients is the Body Mass Index (BMI). National Institutes of Health Stroke Scale (NIHSS) is a systematic examination to determine the severity stroke. The aim of this study is to determine the relationship of body mass index (BMI) with ischemic stroke severity in patients at Neurology Ward Dr. Moewardi Hospital. Methods: This was an observational study with cross sectional analytic. A total of 32 subjects were selected by purposive sampling, they were ischemic stroke patients in the Neurology Ward Dr. Moewardi Hospital. Data were collected by direct interview, direct measurement of weight and height also examination of severity stroke patient by using NIHSS score. Data analysis used multiple logistic regression models and were processed with Statistical Product and Service Solutions (SPSS) 17.00 for Windows. Results: Multiple logistic regression showed OR = 17,690; CI 95% 1,190 – 263,039; and p = 0,037. These results have been earned by controlled the confounding variables of age, blood pressure, blood sugar levels, cholesterol levels and smoking history. Conclusions: Ischemic stroke patients with high BMI score has risk of ischemic stroke severity 17.690 times higher than whose normal BMI score.There is a strong relationship between body mass index (BMI) with the severity of ischemic stroke patients at Neurology Ward of Dr. Moewardi Hospital, the relationship is statistically significant in this study. Keywords:BMI, Stroke Severity, Ischemic Stroke
Hubungan Lama Sakit dengan Status Gizi Anak Penderita Talasemia di RSUD Dr. Moewardi Anisa, Ilma; Riza, Muhammad; Moelyo, Annang Giri
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Systemic complications that occur in children with thalassemia like hepatomegaly, hemosiderosis, bone deformities can affect nutrition disorder and growth retardation. The longer someone has suffered thalassemia, the more likely for the systemic disorder occurred. The aims of this study to find out the correlation between duration of illness with nutritional status of children with thalassemia in Dr. Moewardi Hospital. Methods: This is an observational analytic study using cross sectional design which was conducted from April to May 2013. Thirty children with thalassemia in the Dr. Moewardi Hospital were fulfill the restriction criteria. The duration of illness was acquired from medical record, while the nutritional status was obtained through measurements of weight, height, and the mid-upper arm circumference. The correlation between the duration of illness, gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status was analyzed by using Spearman test followed by the multivariate logistic regression analysis. Results: Spearman test analysis showed no significant correlation between duration of illness with nutritional status in children with thalassemia according to the weight/age and height/age indicator (p = 0,403 and p = 0,408). From the result of analysis on correlation between gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status according to the weight/age and height/age indicator (p &gt; 0,05). Conclusions: There is no significant correlation between the duration of illness with the nutritional status of children with thalassemia according to the weight/age and height/age indicator in Dr. Moewardi Hospital. There is no correlation between gender, blood transfusion, iron chelating agents, splenomegaly, and 1 day food recall with nutritional status. Keywords: Duration of Illness, Nutritional Status, Thalassemia 

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