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Berkala Ilmu Kesehatan Kulit dan Kelamin
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Articles 277 Documents
DERMOSCOPY SUPPORTS THE DIAGNOSE OF PAPULOSQUAMOUS DISORDERS Alinda, Medhi Denisa; Hutomo, Marsudi; Setyaningrum, Trisniartami
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Fakultas Kedokteran Universita Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V26.3.2014.1-7

Abstract

Background: The diagnose of papulosquamous skin disorder was established by clinical symptoms. However, some of papulosquamous manifestation are alike with each other and lead to misdiagnostic. Histopathology examination usually can help to establish diagnose but this method is invasive and time consuming. Purpose: To evaluate dermoscopic features of papulosquamous disorder. Methods: Descriptive observasional cross sectional study, total sampling in ward and out patient clinic of Dermato-venereology Department Dr. Soetomo General Hospital. Twenty four samples were included in the study, followed by the procedures from anamnesis, physical examination, dermoscopy procedures, and histopathology examination. Results: From 24 samples, 19 samples showed plaque psoriasis describing 12 ring patterns, 1 cluster pattern, 2 patchy patterns, 2 reguler patterns, and 2 unspesi?c patterns; 3 samples showed nummular dermatitis describing 2 cluster patterns and 1 unspesi?c pattern; and 2 samples showed pityriasis rosea describing 2 pheripery patterns. Conclusion: Dermoscopy can support the diagnosis of papulosquamous skin disorder especially plaque psoriasis.Key words: papulosquamous disorder, dermosocopy, histopathology examination, plaque psoriasis.
KI-67 IMMUNOHISTOCHEMISTRY EXAMINATION IN PITYRIASIS RUBRA PILARIS Sari, Diana Kartika; Prakoeswa, Cita Rosita Sigit; Soemarno, Troef
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Fakultas Kedokteran Universita Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V26.3.2014.1-5

Abstract

Background: Pityriasis rubra pilaris (PRP) is a papulosquamous disorder of unknown etiology. PRP is often difficult to be distinguished with psoriasis in early phase of the disease. Purpose: To deliver information about Ki-67 immunohistochemistry examination in PRP. Reviews: The diagnosis of PRP can be established by histological examinations or even immunohistochemistry. The best treatment options are retinoids, photochemotherapy (PUVA), and antimetabolites (methotrexate). Conclusion: Immunohistochemistry examination can provide complete feature to distinguish between PRP and psoriasis because of it's high specifity.Key words: Ki-67 immunohistochemistry, pityriasis rubra pilaris, diagnosis.
PENGARUH DERMATITIS ATOPIK, URTIKARIA DAN GANGGUAN SALURAN CERNA SEBAGAI KOMORBIDITAS DALAM PERBAIKAN KLINIS DAN KEPUASAN ORANG TUA PASIEN PADA ANAK ALERGI DENGAN GEJALA SALURAN NAFAS TINGKAT MODERATE-PERSISTENT YANG MENDAPATKAN IMUNOTERAPI ALERGEN DEBU RUMAH Endaryanto, Anang
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 31, No 2 (2019): AGUSTUS
Publisher : Fakultas Kedokteran Universita Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V31.2.2019.112-122

Abstract

Latar Belakang: Rendahnya efektivitas imunoterapi dan kepuasan orang tua perlu dieksplorasi untuk menurunkan angka dropout imunoterapi yang masih tinggi. Tujuan: mengevaluasi pengaruh keberadaan gejala alergi di luar saluran nafas pada efektivitas imunoterapi dalam meredakan gejala alergi dan kepuasan para orang tua. Metode: Penelitian dilaksanakan mulai 1 Januari 2008 sampai 31 Desember 2018 dengan disain kohort retropektif pada anak alergi debu rumah dengan gejala saluran nafas moderate-persistent yang diberikan imunoterapi alergen debu rumah subkutan. Setelah fase rumatan imunoterapi selesai, tingkat gangguan kualitas hidup dan frekuensi gejala, jumlah hari/minggu bebas gejala alergi, dan tingkat kepuasan orang tua dievaluasi dalam 30 hari. Hasil: Sejumlah 100 % dari total subjek penelitian (2,171 pasien) sensitif pada alergen debu rumah dengan gejala saluran nafas. Sebesar 79,7 % pasien membaik menjadi mild-intermittent. Rerata jumlah hari bebas gejala pada 30 hari paska fase rumatan imunoterapi adalah 25,1 + 8,31 hari. Tingkat kepuasan yang tinggi dinyatakan oleh 72,9 % orangtua pasien. Adanya komorbiditas dermatitis atopik, urtikaria, dan gejala alergi saluran cerna tidak berpengaruh terhadap skor perbaikan gejala alergi saluran nafas. Keberadaan dermatitis atopik, urtikaria, dan gangguan saluran cerna berkorelasi dengan penurunan jumlah hari bebas gejala. Simpulan: Keberadaan dermatitis atopik, urtikaria, dan gangguan saluran cerna sebagai komorbiditas tidak menurunkan efektivitas imunoterapi alergen debu rumah dalam meredakan gejala alergi saluran nafas, tetapi menurunkan jumlah hari/minggu bebas dari gejala alergi dan tingkat kepuasan orang tua pasien.
KESESUAIAN GAMBARAN KLINIS PATOGNOMONIS INFESTASI SKABIES DENGAN KEPOSITIFAN PEMERIKSAAN DERMOSKOP DAN KEROKAN KULIT Kurniati, Kurniati; Zulkarnain, Iskandar; Listiawan, M. Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Fakultas Kedokteran Universita Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V26.1.2014.1-8

Abstract

Latar belakang: Diagnosis infestasi skabies oleh klinisi umumnya ditegakkan dengan gejala klinis patognomonis skabies. Tetapi gejala skabies seringkali tidak khas akibat adanya kemiripan dengan penyakit lain terutama pada anak-anak dan kondisi imunokompromais, sehingga diagnosis klinis seringkali keliru dan mengakibatkan kesalahan pemberian terapi. Diperlukan penegakan diagnosis definitif untuk menemukan Sarcoptes scabiei (S. scabiei) atau telurnya, yang secara konvensional dapat dilakukan dengan pemeriksaan mikroskopik dari kerokan lesi kulit penderita. Namun metode tersebut tidak praktis, membutuhkan keterampilan khusus, cenderung invasif, seringkali memerlukan beberapa kali kerokan, serta sulit dilakukan pada anak-anak, sehingga diperlukan metode yang mudah, non-invasif, dan akurasi yang baik. Pemeriksaan dermoskop menawarkan solusi tersebut. Tujuan: Mengevaluasi kesesuaian gambaran klinis patognomonis infestasi skabies dengan kepositifan dermoskop dan pemeriksaan kerokan kulit Metode: Studi analitik observasional cross sectional, total sampling dalam satu kali observasi pada 243 populasi terjangkau yang berusia 5-14 tahun di satu pondok pesantren. Terdapat 44 sampel yang memenuhi kriteria penerimaan sampel yang dilakukan anamnesis dan pemeriksaan fisik untuk menentukan gejala klinis patognomonis skabies, selanjutnya diperiksa dengan dermoskop dan mikroskop dari kerokan kulit pada lesi. Analisis hasil dengan menghitung kappa agreement dan nilai prediksi positif. Hasil: Dari 44 sampel didapatkan 25 sampel klinis patognomonis skabies dan 19 sampel klinis non patognomonis skabies. Pemeriksaan dermoskopi ditemukan positif pada 25 sampel dan mikroskopik kerokan kulit positif pada 18 sampel. Kesesuaian dermoskopi dan kerokan kulit adalah 79,5%, kappa 0,601. Simpulan: Dermoskop berpotensi digunakan sebagai alat diagnostik definitif skabies pada lingkungan dengan prevalensi tinggi skabies. Kata kunci: skabies, dermoskop, kerokan kulit.
Penatalaksanaan Kandidiasis Mukokutan pada Bayi Kusumaputra, Bagus Haryo; Zulkarnain, Iskandar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (489.015 KB) | DOI: 10.20473/bikkk.V26.2.2014.1-7

Abstract

Latar belakang: Bayi memiliki risiko lebih tinggi terhadap cedera kulit, absorbsi kulit, dan infeksi kulit. Kandidiasis mukokutan pada bayi dapat berupainfeksi yang paling umum seperti kandidiasis oral dan ruam popok, sampai berupa infeksi serius yang berpotensi menjadi infeksi sistemik, seperti kandidiasis kongenital dan dermatitis fungal invasif. Infeksi mukokutan pada bayi prematur dapat menjadi permulaan infeksi sistemik sehingga membutuhkan perhatian khusus.Tujuan: Memberikan pengetahuan mengenai kandidiasis mukokutan pada bayi yang meliputi etiopatogenesis dan manifestasi klinis, sehingga diharapkan dapat memberikan pengobatan yang lebih baik. Telaah kepustakaan: Lokasi utama kontak dengan kandida pada bayi baru lahir yang tersering adalah mukokutan, termasuk saluran pencernaan, pernapasan, dan kulit. Faktor predisposisi kandidiasis meliputi faktor mekanik, nutrisi, perubahan fisiologis, penyakit sistemik, dan faktor iatrogenik. Diagnosis kandidiasis mukokutan berdasarkan pemeriksaan klinis ditunjang dengan pemeriksaan mikroskop langsung dan kultur. Pengobatan kandidiasis mukokutan pada bayi meliputi pengobatan topikal dan sistemik. Golongan antijamur topikal yang digunakan pada kandidiasis antara lain imidazol dan poliene, sedangkan pengobatan antijamur sistemik meliputi flukonazol dan amfoterisin B. Simpulan: Pengobatan kandidiasis mukokutan pada bayi sebagian besar menggunakan obat topikal. Pengobatan sistemik digunakan bila terapi topikal gagal atau pada infeksi kandida yang terdapat gejala sistemik.Kata kunci: kandidiasis mukokutan, bayi, tatalaksana.
Retrospective Study of Skin Prick Test in Atopic Dermatitis Patients at DermatoVenereology Outpatient Clinic of Dr. Soetomo General Hospital Surabaya During 2007-2012 Natallya, Fransiska Rismauli; Barakbah, Jusuf
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (124.433 KB) | DOI: 10.20473/bikkk.V27.1.2015.9-16

Abstract

Background: Atopic dermatitis (AD) gives impact on quality of life of patients because of  frequent exacerbation. Various factors play a role in pathogenesis of AD. Trigger factors of exacerbation especially due to enviroment including irritant and allergen agents. Identifying and avoiding trigger factors are important in management of AD. Skin prick test (SPT) is one method to detect the presence of Ig E spesific to certain allergens (food allergens, aeroallergens). Purpose: To describe the characteristic of AD patients, and evaluate the result of SPT and their clinical relevance. Methods: This research was a retrospective study of AD patients who underwent SPT  during 2007-2012. Results: Nineteen of 57 patients (33,3%) had positive SPT to one or more allergens, and 36 patients (63,1%) had negative result. One patient (1,8%) showed false positive result and 1 patient (1,8%) showed false negative result. The most common allergens were house dust in 8 patients (42%) and crab in 6 patients (31,6%). Clinical relevance was found in 11 patients (58%), and 8 patients (42%) had no clinical relevance. Compared with SPT–negative patients, SPT–positive patients showed more severe symptom and clinical manifestation. Conclusions: In this study, the allergens could be detected in 19 patients (33,3%) by SPT, mostly to house dust (42%) and crab (21,6%). Clinical relevance was found in 11 patients (58%). SPT is recomended to perform in management of AD in order to detect enviromental allergen because it has significant clinical relevance. Key words: atopic dermatitis, skin prick test, allergens.
Retrospective Study: Oral Medications for Atopic Dermatitis Widia, Yuri; Hutomo, Marsoedi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.408 KB) | DOI: 10.20473/bikkk.V27.2.2015.130-136

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease, characterized by recurrent itch. The prevalence of AD in children is 10-20%, while in adults is as many as 1-3%. Several factors are proposed to play role in the pathogenesis of AD as well as genetics, immunological, and environmental factors. There are recent advances in the management of the AD but still not fully satisfactory. Purpose: To evaluate oral medications for AD to improve patients care in the future. Methods: Retrospective study performed in Allergy Immunology Division of Dermatology and Venereology Outpatient Clinic Dr. Soetomo th stGeneral Hospital within January 1 2009 until December 31 2011. Data was collected from medical records. Results: There were 11.7% AD patients who received oral treatment. The most antihistamine given was mebhydrolin napadisilat in 51.5% of patients. The most corticosteroids given was dexamethasone in 33.6% patients. Dexamethasone was given in tapering off in 7.9% patients. The most oral antibiotics given was erythromycin in 4.8% patients and cloxacillin in 0.3% patients. Conclusions: Oral medications mostly used in AD was antihistamine. Some patients were also given corticosteroids. Antibiotics were used if secondary bacterial infection was assessed.Key words: atopic dermatitis, retrospective study, oral medications.
Cara Penularan HIV & AIDS Di Unit Perawatan Intermediate Penyakit Infeksi (UPIPI) RSUD Dr. Soetomo Surabaya Astindari, Astindari; Lumintang, Hans
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.29 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-5

Abstract

Latar belakang: Kasus HIV & AIDS makin lama makin meningkat. Sejak pertama kali dilaporkan pada tahun 1987 sampai 2009, di Indonesia tercatat 3.492 orang meninggal dunia karena penyakit ini. Cara penularan HIV & AIDS di Indonesia selalu mengalami perubahan. Awalnya cara penularan terjadi melalui hubungan heteroseksual. Kemudian peningkatan jumlah pengguna narkoba suntik (penasun) di Indonesia menyebabkan cara penularan HIV & AIDS juga mengalami perubahan karena penularan bisa terjadi melalui penggunaan jarum suntik bersama di kalangan para penasun. Saat ini cara penularan HIV & AIDS kembali lagi, terutama melalui hubungan heteroseksual. Perubahan cara penularan HIV & AIDS dari kelompok penasun ke heteroseksual mempengaruhi strategi pencegahan penularan HIV & AIDS di Indonesia, khususnya di RSUD Dr. Soetomo Surabaya. Tujuan: Mengevaluasi cara penularan HIV & AIDS di UPIPI RSUD Dr. Soetomo Surabaya tahun 2006-2010. Metode: Penelitian deskriptif, retrospektif tentang cara penularan HIV & AIDS di UPIPI RSUD Dr. Soetomo Surabaya tahun 2006 – 2010. Hasil: Kasus baru HIV & AIDS di UPIPI RSUD Dr. Soetomo Surabaya tahun 2006-2010 didapatkan 3.090 kasus, dengan perbandingan pasien laki-laki lebih banyak dari pasien perempuan. Cara penularan tertinggi melalui hubungan seksual yaitu 63,5%, cara penularan berikutnya melalui penasun 24,8%, penasun + seksual 6,3%, dan perinatal 3,2%. Cara penularan melalui heteroseksual makin meningkat dari tahun 2006 sebanyak 186 orang (47,1%) menjadi 509 orang (71,9%) pada tahun 2010. Simpulan: Cara penularan HIV & AIDS di UPIPI RSUD Dr. Soetomo mengalami perubahan, yang semula terbanyak melalui penasun pada tahun 2005 berubah melalui heteroseksual pada tahun 2010. Hal itu akan mempengaruhi strategi upaya pencegahan penyakit tersebut. Kata kunci: studi retrospektif, HIV & AIDS, penularan, heteroseksual, IDUs, penasun, perinatal.
Urticaria and Angioedema: Retrospective Study Wirantari, Nadia; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.918 KB) | DOI: 10.20473/bikkk.V26.3.2014.1-7

Abstract

Background: Urticaria is a common disorder that often presents with angioedema. Angioedema which may lead to laryngeal involvement, asphyxiation, and urticaria lasting more than 72 hours, are indications of hospitalization. Purpose: To describe the distribution, duration of hospitalization, trigger factor, clinical form, diagnostic, and therapeutic approach in urticaria and angioedema patients in Dermaro-venerelogy Departement Dr. Soetomo General Hospital during year 2011-2013. Methods: Retrospective study using medical records of new patients with urticaria and/ or angioedema in Dermatovenereology Ward st thduring 1 January 2011 until 31 December 2013. Basic data, anamnesis, physical examination, diagnostic, and therapeutic approach are recorded. Results: There were 42 new patients with urticaria and/or angioedema (2.3% of all Dermatoveneorology inward patients), with mean length of stay 4-6 days (57.1%), chief complaint of itch, hives, and swelling (42.8%), lesions occur for less than 6 weeks (92.9%), for the first time (54.8%), with episodes of less than 72 hours (45.3%). Urtica and angioedema were the most often clinical findings (38.1%), complete blood count and urinalysis were routinely examined (100% and 97.6% respectively). Treatment combination of corticosteroid and antihistamin H1 was the most commonly prescribed (64.0%). Conclusion: Urticaria along with angioedema was the most common condition in inward patients, thus combination therapy of antihistamin H1 and corticosteroid were most often needed.Key words: urticaria, angioedema, retrospective study.
Eosinophil and Eosinophil Cationic Protein Level Raising in Dermatitis Due to Food Patients Umborowati, Menul Ayu; Sawitri, Sawitri; Hoetomo, Marsoedi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.225 KB) | DOI: 10.20473/bikkk.V27.2.2015.90-96

Abstract

Background: Food allergy prevalence worldwide has been increase. Skin is secondary most often target organ in food allergy reaction. Food allergy affects 35% atopic dermatitis (AD) patients. Diagnosis of food allergy  is still challenge because signs are not specific. Previous researches showed eosinophil and eosinophil cationic protein (ECP) role in food allergy reaction on gastrointestinal tract, but none on dermatitis due to food. Purpose: To evaluate eosinophil and serum ECP in dermatitis due to food. Method: This is a descriptive observational cross sectional study, with dermatitis due to food patients in Dermatovenereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya as subjects. Subjects has been collected trough consecutive sampling during 3 months, then data were analysized descriptively Results: Serum ECP level of dermatitis due to food patients were above normal range in all subjects, with mean level 108.5 µg/L, lowest level 33.011 µg/L and higher level 284.849 µg/L. Mean eosinophil of dermatitis due to food patients just arise above normal limit (0.413µg/L). AD patients were 48.4% among all subjects. Mean serum ECP level of AD patients was higher (121.703 µg/L) than non-AD (96.123 µg/L). Conclusions: Eosinophil and ECP seems have role in dermatitis due to food pathogenesis. Serum ECP examination can be benefits to monitor dermatitis due to food severity.Key words: dermatitis due to food, eosinophil, serum eosinophil cationic protein.

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