Mahmiah Mahmiah
Laboratory of Chemistry, Hang Tuah University, Jl. Arif Rahman Hakim 150 Surabaya

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : UNEJ e-Proceeding

PHYTOCHEMICAL AND ANTIOXIDANT ACTIVITY of MANGROVE PLANT Soneratia sp. Mahmiah, Mahmiah; Andayani, Rina
UNEJ e-Proceeding 2016: Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UNEJ e-Proceeding

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

At the moment, plants use as medicine are mostlyland plants, while plants derived from water such asmangroves have not received much attentions.Some of the mangrove plants that can be used asmedicine are Acanthus ilicifolius, Avicennia alba,Avicennia marina, Avicennia offinalis, Bruguieracylindrical, Bruguiera exaristata, Bruguieragymnorrhiza, Ceriops tagal, Hisbiscus tiliaceus,Ipomoea pes-capre, Lumnitzera racemosa, Nypafructicans, Pluchea indica Rhizophora apiculata,Soneratia sp., dan Sonneratia alba. The plants wereutilized as antiasma, antidiuretic, antidiabetic, itchrelieve, etc. Purnobasuki, 2004).One of the mangroves that are often found on theEast Coast of Surabaya, East Java is Soneratia sp ..which is classed as true mangrove flora.Ethnobotanically, the wood and stem are used astraditional medicine as pain reliever. Based onresearch conducted by Mahmiah (2012)studyingphytochemical aspect of Avicennia marina from eastcoast region of Surabaya,it was known that the stemand leaves of the plant contained phenoliccompounds.Taking into account the existence of the waves andextreme weather conditions in the East Coast regionof Surabaya, it was hypothesized that the secondarymetabolite compounds produced by the plantswould be different. Based on that hypothesis it wasnecessary to do a research on Soneratia sp. plantlocated on the East Coast of Surabaya with the aimof exploring the content of secondary metabolitesfrom the stem of the plant.Methods that were used to accomplish that aimwere (1) preliminary test; (2) phytochemicalscreening; (3) GC-MS analysis and (4) antioxidanttest
ANTIOXIDANT ACTIVITY OF METHANOL EXTRACTS FROM THE STEM BARK OF MANGROVE PLANT Rhizophora mucronata Mahmiah, Mahmiah; Giman, Giman; Aminah, Nanik Siti; Tanjung, Mulyadi
UNEJ e-Proceeding 2016: Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UNEJ e-Proceeding

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Numbers of diseases such as stroke, diabetes, gout,and even cancer are caused by the reaction of freeradicals (oxidants) found in the body. Those diseasescurrently have not yet controlled. Deleteriouslifestyle, lack of exercise, or genetics can be thetrigger to this oxidant. Based on Chemotaxonomic,drugs that have been used to inhibit the oxidationprocess or termination stage of free radicals containthe active ingredient in the form of secondarymetabolites of alkaloids, phenolics, terpenoids andsteroids. For example, phenolic compounds such asflavonoids, xanthones, antioxidants and polyphenolsis a good agent because it has a structure with a highdegree of oxidation (Suares, et al, 2010).Researches related to the exploration of antioxidantactive ingredient has been more focused onsecondary metabolites found in terrestrial plants.The development of natural compounds potential ofmarine plant material such as mangrove are still notreceived much attention. Spalding et al. in 2001explained that mangroves plant in Indonesia is thehighest in the world, both in terms of quantity area(± 42 550 km2) as well as the number of species (±45 species). This basic natural resource of Indonesiamangrove is certainly valuable promisingopportunities to be expanded as a biological drug.Mangroves plant that commonly used as medicinediscovered from various species i.e: Acanthusilicifolius, Avicennia alba, Avicennia marina,Avicennia offinalis, Bruguiera cylindrical, Bruguieraexaristata, Bruguiera gymnorrhiza, Ceriops tagal,Hisbiscus tiliaceus, Ipomoea pes-capre, Lumnitzeraracemosa, Nypa fructicans, Pluchea indicaRhizophora apiculata, Rhizophora mucronata andSonneratia alba. Those plants are usually utilized asantiasma, antidiuretic, antidiabetic, reliever itching,and others. (Purnobasuki, 2004).The potential of mangroves as a drug is veryimportant to be developed considering the need fordrugs is increasing deals with the growing ofpopulation and many kinds of diseases such ascancer, hypertension, tumor diseases and diseasescaused by chemical or biological waste pollutionfrom viruses and bacteria. People are more likely tochoose drugs that are natural because relatively takefew side effects or even none at all.Several studies of mangrove plants from genusRhizophora that have antioxidant bioactivity areshown in the crude butanol extract of mangrove R.apiculata with IC50 33.34 pg / mL (Gao, 2012). Themethanol extract of R. mangle’s stem were alsodocumented to have antioxidant activity (Palacio, etal, 2014).One of mangroves found in Surabaya East Coastal(Pamurbaya), East Java, Indonesia is the mangroveRhizophora mucronata. This mangrove species isindigenous mangroves that ethno-botanicallypopular used as a pain reliever and dyes naturalwood. Secondary metabolites contained in theleaves, bark, stems, roots, and fruit are different inquantity. The content of secondary metabolites inplant commonly used as a medicine is from generalpart of the bark. Therefore, on the basis ofchemotaxonomic and ethno-botany of mangroves R.mucronata, this study aims to explore the bioactivityof antioxidant from the stem bark of R. mucronata.