Majalah Kedokteran Neurosains
Vol 26 No. 4 Juli 2009

Peran Sitokin dalam Mekanisme Nyeri Neuropatik

Thomas Eko P, Purna Putra (Unknown)



Article Info

Publish Date
07 Jan 2015

Abstract

RECENTLY IT BECOME CLEAR THAT INFLAMMATORY AND IMMUNE MECHANISM BOTH IN THE PERIPHERY AND THE CENTRAL NERVOUS SYSTEM PLAY AN IMPORTANT ROLE IN NEUROPATHIC PAIN INFILTRATION OF INFLAMMATORY CELLS AS WELL AS ACTIVATION OF RESIDENT IMMUNE CELLS IN RESPONSE TO NERVOUS SYSTEM DAMAGE LEADS TO SUBSEQUENT PRODUCTION AND SECRETION OF VARIOUS INFLAMMATORY MEDIATORS THESE MEDIATORS PROMOTE NEUROIMMUNE ACTIVATION AND CAN SENSITIZE PRIMARY AFFERENT NEURONS AND CONTRIBUTE TO PAIN HYPERSENSITIVITY INFLAMMATORY CELLS SUCH AS MAST CELLS NEUTROPHILS MACROPHAGES AND T LYMPHOCYTES HAVE ALL BEEN IMPLICATED AS HAVE IMMUNELIKE GLIAL CELLS SUCH AS MICROGLIA AND ASTROCYTES

Copyrights © 2009






Journal Info

Abbrev

NEURONA

Publisher

Subject

Neuroscience

Description

Neurona merupakan satu-satunya jurnal yang memuat perkembangan penelitian dan kasus terbaru bidang neurosains di Indonesia. Jurnal ini diterbitkan setiap 3 bulan sekali oleh Perhimpunan Dokter Spesialis Saraf di Indonesia. Pastikan Anda telah terdaftar menjadi pelanggan untuk dapat mengunduh artikel ...