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Contact Name
Salman, S.Si, M.Farm
Contact Email
salman.kimia@gmail.com
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+6285277011177
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admin@journal-jps.com
Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot SUbroto Gg. Rasmi No.28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123
Location
Kota medan,
Sumatera utara
INDONESIA
Journal Pharmaceutical And Sciences
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490
Core Subject : Health, Science,
Jurnal Journal of Pharmaceutical and Sciences (JPS) adalah jurnal elektronik yang diterbitkan Fakultas Farmasi Universitas Tjut Nyak Dhien. Jurnal ini dapat diakses secara online di https://www. journal-jps.com . Jurnal Journal of Pharmaceutical and Sciences (JPS) merupakan media publikasi ilmiah bagi dosen, mahasiswa, peneliti bidang farmasi dan sains terapan, juga bagi pratiksi farmasi baik di industri, rumah sakit maupun dilembaga penelitian lainnya. Jurnal Journal of Pharmaceutical and Sciences (JPS) menerima artikel berupa hasil penelitian, telaah atau tinjauan literatur, penelitian singkat atau short communication yang terkait dengan bidang pengetahuan tentang teknologi farmasi, manajamen farmasi, farmasi klinis, analisa kimia, bioteknologi, kimia bahan pangan, farmakologi, kimia bahan alam, material farmasi, kesehatan dan sains terapan yang relevan dengan bidang farmasi. Jurnal Journal of Pharmaceutical and Sciences (JPS) terbit 2 (dua) kali setahun yaitu nomor 1 di rentang waktu bulan Januari sampai Juni dan nomor 2 di bulan Juli sampai Desember setiap tahunnya.
Articles 9 Documents
Search results for , issue "Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)" : 9 Documents clear
GAMBARAN PENGETAHUAN MAHASISWA FAKULTAS FARMASI UNIVERSITAS TJUT NYAK DHIEN MEDAN TERHADAP PENGGUNAAN ANTIBIOTIK Hasanah, Fenny; Siahaan, Desy Natalia
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.26

Abstract

Antibiotic abuse by using it alone without consulting a doctor on students continues to be a significant problem in developed and developing countries. This is because many cases of antibiotics are used irrationally so that they are directly related to the possibility of resistance. The purpose of this study was to determine the level of knowledge of Tjut Nyak Dhien University Pharmacy Faculty students in Medan on the use of antibiotics. This study used a descriptive analytical approach using a questionnaire. The results showed that of 232 students 52% of students had high knowledge, 38% of students had moderate knowledge and 10% of students had low knowledge.
Formulasi dan Uji Stabilitas Fisik Sediaan Salep Dari Ekstrak Etanol Daun Pare (Momordica Charantia L) Sebagai Obat Luka Fauziah, Fauziah; Widiyanti, Siti Arum; Rinaldi, Rinaldi; Silviana, Ernita
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.19

Abstract

Bitter melon leaves contain secondary metabolites such as flavonoids, tannins, saponins, steroids, alkaloids, and terpenoids which can inhibit bacterial growth. Bitter melon leaves can be used as a medicine, one of which is to treat wounds because they have bacterial inhibition and can cover wounds. This study aims to determine the effect of the basis on the stability of ointment and to find out which formulations meet the stability requirements of ointment. This type of research is experimental. The base of the ointment used is the base of the hydrocarbon ointment and the base of the absorbent ointment. The extract of pare leaf extract was carried out by maceration using 70% ethanol. The pare ethanol extract ointment was made in 3 formulas using the same base and different concentrations of the extract. Preparation of ointments using the smelting method. Evaluation of ointment was carried out by organoleptic test, homogeneity test, pH measurement test, and dispersion test. The test results of all ointment preparations from the formula I, formula II and formula III met the organoleptic test quality parameters, homogeneity and pH test. For the spread test on each formula, the only formula I approach the physical stability test parameter.
Skrining Aktivitas Antibakteri Fraksi Kelopak Bunga Mussaenda frondosa L. Efendi, M. Rifqi
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.18

Abstract

Background: Antibiotics are the most effective drugs against microbial infections, but slowly lose their efficacy to microorganisms due to resistance. So, nowadays, research related to finding new compounds from nature to treat infectious diseases has become important. Mussaenda frondosa L. is a tropical plant native to Indonesia. Traditionally, Mussaenda frondosa L. has been used for the treatment of various diseases, such as headaches and jaundice. The literature study of the antibacterial activity of Mussaenda frondosa L. is still very limited, so research needs to be done regarding the antibacterial activity. Objective: to determine whether there is antibacterial activity from Mussaenda frondosa L. petal fraction. And whether there is significant antibacterial activity when it is compared to chloramphenicol as positive control antibiotic. Method: The methodology of this research starts with sampling, sample identification, extraction, and fractionation. Screening for antibacterial activity was carried out by the agar diffusion method. Results: The most potential antibacterial activity was ethyl acetate fraction with an inhibitory diameter of 5.6 - 8.3 mm against 12 test pathogenic bacteria, except Streptococcus mutans ATCC 25175. The n-hexane fraction showed antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853 and Vibrio cholerae inaba with an inhibitory diameter of 6.0 - 7.5 mm. Meanwhile, the n-butanol fraction has only antibacterial activity against Staphylococcus aureus ATCC 25923 with a 7.5 mm inhibition diameter. Conclusion: the most potential fraction that had antibacterial activity was ethyl acetate fraction, by inhibiting 12 test pathogenic bacterias, followed by n-hexane fraction which inhibits 3 bacterias.
Uji Aktivitas Antioksidan Ekstrak Etanol Fraksi Heksan, Fraksi Etil Asetat dan Fraksi Air Daun Kapulaga (Elettaria cardamomum (L.) Maton) ASRA, RIDHO; Azni, Nize Ria; Rusdi, Rusdi; Nessa, Nessa
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.17

Abstract

This study aims to determine the antioxidant activity of the ethanol extract, hexane fraction, ethyl acetate fraction and water fraction of cardamom leaves (Elettaria cardamomum (L.) Maton). Dried of cardamom leaves was extracted by maceration using 70 % ethanol, then followed by fractionation based on the level of polarity with hexane, ethyl acetate, and water solvents. Antioxidant activity examination was determined using reagent DPPH using UV-Visible spectrophotometry and gallic acid as standard. The results of phytochemical screening showed that ethanol extract and water fraction of cardamom leaves contains phenol, flavonoids, tannins, and saponins, for ethyl acetate fraction contains phenol, flavonoids, and tannins, for hexane fraction the results were negative for all the compounds tested. The results of the antioxidant activity examination of ethanolic extract, hexane fraction, ethyl acetate fraction and water fraction of cardamom leaves showed the IC50 of 4058.7 μg/mL, 8419.3 μg/mL, 2281.7 μg/mL, and 3889.6 μg/mL respectively, whereas gallic acid showed the IC50 value of 4.89 μg/mL. Based on IC50 values ethanol extract, hexane fraction, ethyl acetate fraction and water fraction of cardamom leaves have weak antioxidant activity compared to gallic acid which has high antioxidant activity.
Pengaruh Hipoglikemia pada Pasien Diabetes Melitus Tipe 2 terhadap Kepatuhan Terapi dan Kualitas Hidup Rusdi, Mesa Sukmadani; Afriyeni, Helmice
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.13

Abstract

Diabetes mellitus (DM) is a metabolic disorder characterized by an increase in blood sugar due to a decreasing in insulin secretion by pancreatic beta cells and/or impaired insulin function (insulin resistance). Based on the International Diabetes Federation (IDF) (2015), Indonesia was ranked 7th in the world with 10 million people suffered from DM. DM can become serious and cause a chronic condition that is dangerous if not treated and not adhered in taking medication. The main risks associated with DM are hypoglycemia, hyperglycemia, diabetic ketoacidosis, dehydration, and thrombosis. The incidence of hypoglycemia can be influenced by age factors, duration of suffering from diabetes, weight, and glycemic control. Acute and chronic complications of hypoglycemia can interfere with life, such as social interaction, sleep, sexual activity, driving, sports, and other activities. The purpose of this study was to determine the effect of hypoglycemia in type 2 DM patients on therapy adherence and quality of life. The design of this study was a cross-sectional study with subjects of the research were adult patients with type 2 DM who used oral anti-diabetes medication for more than 6 months. Patients who have a history of hypoglycemia are divided into 3 groups, namely (1) Having hypoglycemia in the last 3 months; (2) Not experiencing hypoglycemia in the last 3 months; (3) Never experience hypoglycemia. Measurement of adherence using the Morisky Modified Adherence Scale (MMAS), measurement of quality of life with Diabetes Quality of Life Questionnaire (DQoL), data obtained will be processed statistically using Chi-Square Test. The result of this study was unable to prove the relationship of hypoglycemia to therapy adherence (p = 0.756; p> 0.05) and the quality of life of patients (p = 0.143; p> 0.05).
ANALISIS KANDUNGAN LOGAM TIMBAL DAN KADMIUM DALAM PRODUK JAMU ASAM URAT DENGAN MENGGUNAKAN SPEKTROFOTOMETRI SERAPAN ATOM Asra, Ridho; Maisitoh, Maisitoh; Rusdi, Rusdi
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.11

Abstract

Analysis of metal contents lead and cadmium in jamu asam urat using atomic absorption spectrophotometric has been done. The aim of this study is to analyze metal contents (lead and cadmium) in jamu asam urat with diffrent brands which are circulate in Padang cyti. Three samples of jamu asam urat with diffrent brands were analyzed the metal contents of lead and cadmium using atomic absorption spectrophotometric. The level of lead metal was obtained using regression equation y = 0.05378 + 0.02963x with R = 0.9977, and the level of cadmium metal was obtained using regression equation y = 0.08236 + 0.23186x with R = 0.9945. The result of this study showed that three samples were not detected containing metal cadmium, but three samples were positive containing metal lead, 2.2055 ppm (samples I), 3.6465 ppm (samples II), and 3.0156 ppm (samples III). The renits showed that all samples qualified for healy metal contamination by BPOM that less than 10 ppm for Pb and less than 0.3 ppm for Cd heavy
Pemanfaatan Sirup Glukosa Hasil Hidrolisa Selulosa dari Dami Nangka (Artocarpus heterophylus Lamk) sebagai Pemanis pada Pembuatan Manisan dari Buah Kelapa (Cocos Nucifera L) Sari, Nurmala
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.12

Abstract

Research on the influence of polysaccharides from the jackfruit rags (Artocarpus Heterophyllus Lamk) on the content of glucose syrups on hydrolyzing with HCl 30% has been done. A sample has got with simple random sampling. The cellulose was isolated from the seeds of rags. The cellulose was hydrolyzed by HCl 30% to produce glucose syrups. The content was analyzed by the Nelson-Somogyi method and calculated by regression analysis. The results of analysis show that the content of glucose syrups from the cellulose from the jackfruit rags were 2.47%. Keywords: cellulose, jackfruit rags, glucose syrups, Hydrolysis
FORMULASI DAN EVALUASI SABUN TRANSPARAN DARI KOLAGEN TULANG SAPI (Bos sp.) SEBAGAI PELEMBAB Zebua, Nilsya Febrika; Sudewi, Sudewi; Prihatini, Masrina
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.10

Abstract

Collagen is one of the proteins that make up the body or the organic structure that builds bones, teeth, joints, muscles, and skin. Collagen is very often used by the community because it is to maintain healthy skin and maintain skin elasticity. This study aims to determine collagen from bovine bones can be formulated into transparent soap preparations. Bovine bone collagen (Bos sp.) was extracted by immersion using 1N NaOH. The production of transparent soap formulas in several concentrations is 0.5%, 1%, 2.5%, and 5% collagen. The bovine bone collagen yield was obtained 27.5%. Collagen in a variety of concentrations produces different colors and the ability to moisturize the skin. Bovine bone collagen (Bos sp.) was formulated in transparent soap preparations from bovine bone collagen (Bos sp.) with a concentration of 0.5% including the category "moist" and transparent soap preparation from bovine bone collagen (Bos sp.) 1% , 2.5%, and 5% including the category of "very humid" and the results of testing on volunteers showed that transparent soap from collagen in bovine bone (Bos sp.) did not cause irritation.
ANALISIS PENYEBAB MEDICATION ERROR PADA FASE PRESCRIBING DI POLIKLINIK PENYAKIT DALAM RSUP H. ADAM MALIK Siahaan, Desy Natalia; Roiman, Robert; Silalahi, urminda; Gunawan, Muhammad
Journal of Pharmaceutical And Sciences Vol 2 No 1 (2019): JPS Volume 2 Nomor 1 (2019)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v2i1.49

Abstract

A medication error is an event that can jeopardize patient safety by health workers, especially in terms of patient treatment services that should be avoided. The occurrence of medication errors can occur in each treatment process, one of which is in the prescribing phase. The prescribing phase is the part when a doctor prescribes a patient's medication. The purpose of this study was to determine the causes and incidence of medication errors in the prescribing phase in the treatment services at H. Adam Malik General Hospital. This research is a prospective study or data collection that is new or ongoing. The research subjects were prescription internal medicine patients who met the inclusion and exclusion criteria with a total sampling method that took a prescription in 2018 at the Outpatient Pharmacy Working Group. The results of the study were obtained from 984 prescriptions for a medication error in the prescribing phase of 33.82%. There was no prescription address, doctor's SIP, date of birth, gender, patient weight, diagnosis, route of administration as much as 100% of the total prescription. Lack of dosage strength, dosage units 49 times each (4.98%), and errors did not write down the name of the complete medical device and the amount was 3 times (0.30%). The main cause is the unavailability of data filling formats or templates on the computer or in the MIRSA Enterprise® application that is used as a recipe management software.

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