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Contact Name
Viskasari P. Kalanjati
Contact Email
majalahbiomorfologi@fk.unair.ac.id
Phone
+6285649348098
Journal Mail Official
majalahbiomorfologi@fk.unair.ac.id
Editorial Address
Departemen Anatomi dan Histologi Fakultas Kedokteran, Universitas Airlangga, Surabaya, Indonesia Jl. Prof Dr Moestopo 47 Surabaya 60132 Indonesia
Location
Kota surabaya,
Jawa timur
INDONESIA
Majalah Biomorfologi
Published by Universitas Airlangga
ISSN : 02158833     EISSN : 27160920     DOI : 10.20473/mbiom.v30i1.2020.1-7
Core Subject : Health, Science,
Majalah Biomorfologi publishes articles in the form of original research report, excel-literature review, communication and special case report. The scope of this journal includes Medicine and Health sciences, focusing in basic and applied Anatomy and Histology (i.e., neuroscience, medical and health education, anthropology, clinical genetics, embryology, medical education, clinical anatomy, histotechnics, and photomicroscopy) although other correlated topics are also welcomed.
Arjuna Subject : Kedokteran - Anatomi
Articles 70 Documents
INFEKSI VIRUS HERPES SIMPLEX PADA BELL’S PALSY Hidayaturrahmi, Hidayaturrahmi; Kalanjati, Viskasari Pintoko
Majalah Biomorfologi Vol 26, No 2 (2013): Majalah Biomorfologi
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.343 KB) | DOI: 10.20473/mbiom.v26i2.2013.22-26

Abstract

Bell’s palsy  disease  is  an acute  idiopathic  peripheral  facial  paralysis  involving  the facial nerve. This disease. This disease is characterized by paralysis and weakness of the facial muscles unilateral with sudden onset and  peak symptoms within a few days.  The etiology  of  this disease  can not be explained  properly. However, some clinical data and immunology shows that the bell’s palsy is  thought to be caused by latent Herpes simplex virus tipe 1 (HSV-1) which is  reactivated  at ganglia  geniculatum  so may provoke an autoimmune reaction against peripheral nerve myelin, leading to the demyelination of facial nerve (N.VII). In the acute phase,  examination of peripheral blood lymphocytes was found a significant reduction of  the percentage of peripheral T lymphocytes and an increase in the percentage of B lymphocytes. In this review, we will also discuss steroids and antiviral therapy as a treatment of Bell’s palsy is currently.
EFFECTS OF LOW DOSE EXPOSURE OF BORAX FOR 8 WEEKS ON GASTRIC ULCER FORMATION Faza, Audi Salman; Dewanti, Linda; Qurnianingsih, Ema
Majalah Biomorfologi Vol 30, No 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (490.038 KB) | DOI: 10.20473/mbiom.v30i1.2020.7-13

Abstract

Background: Borax, a carcinogenic toxicant, is illegally used as food additives frequently. Previous researches shown that high dose of borax exposure (300 mg/kg of BW) caused gastric ulcer, but low dose of borax, as found as usual dose in food, has not been frequently researched. Objective: The aim of this study was to analyze the effects of low dose of borax for 8 weeks on the formation of gastric ulcer. Materials and Methods: Twenty four young adult rats (Rattus norvegicus) were divided into 4 groups (Control, Group 1, 2, and 3). Borax doses of 50 mg/kg, 150 mg/kg, and 300 mg/kg were administered on groups 1, 2, and 3 respectively through sonde for 8 weeks; Control group was not exposed with borax. Body weight was monitored every 2 weeks. On the last day of the experiment, rats were euthanized and gastric ulcers were histopathologically analyzed using a microscope. The data were analyzed by the comparative test of Mann-Whitney and the significancy was set on p<0.050. Results: The results showed that body weight was significantly different on the 6th week between Control vs Group 1 (p=0.010) and Control vs Group 3 (p=0.043). The grade of gastric ulcer was found higher in Group 2 and Group 3 compared to Control (p=0.019 and 0.011 respectively). Conclusion: Both of low dose (150 mg/kg BW) and high dose (300mg/kg BW) of borax exposure for 8 weeks cause microscopic gastric ulcer on rats.
Front Matter vol. 30 no. 2 July 2020 Biomorfologi, Majalah
Majalah Biomorfologi Vol 30, No 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

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FOCAL CORTICAL DYSPLASIA Purwidyastuti, Desy; Kalanjati, Viskasari Pintoko
Majalah Biomorfologi Vol 25, No 1 (2012): Majalah Biomorfologi
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.74 KB) | DOI: 10.20473/mbiom.v25i1.2012.8-12

Abstract

Cortical dysplasia or  focal  cortical dysplasia (FCD) is one of the most common causes of seizures and childhood epilepsy. It is one of some malformation types of cortical development. By using magnetic resonance imaging (MRI) or another radiographic modality, it is not easy to detect its abnormalities. Focal cortical dysplasia was firstly recognized by surgery of intractable epileptic patients. This review is written to describe malformation cortical development (MCD) especially focal cortical dysplasia, its embryology and abnormalities. Cerebral cortex has 6 layer which characteristically different in each of them. Neurons from those layers come from subpial neurons which had migrated to cortical layers according to its ages and functions. The younger ages of neurons will be placed more superficially. Disrupting at any stages of cortical development will be manifested in abnormalities of brain cortex. There are some classifications of MCD according to those cell morphology, Electro Encephalography (EEG), embryology and genetic. Focal cortical dysplasia  might be caused by disrupting in late stages of cortical development.  Focal cortical dysplasia can be distinguished in to two groups, the group I and group II. Microscopically between those groups could be distinguished by borders of the layers. In FCD there is alteration of neurotransmitter effect which is γ-amino butiric acid (GABA) in synaptic process. Its alteration causes seizures, epilepsy or other abnormalities which could be occurred in prenatal or perinatal period. Those seizures or epilepsy often drug resistant.
KARAKTERISTIK PASIEN TUBERKULOSIS TULANG BELAKANG DI RSUD DR. SOETOMO SURABAYA Sukamto, Amy Rosalie; Airlangga, Primadenny Ariesa; Yuliawati, Tri Hartini
Majalah Biomorfologi Vol 29, No 1 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.077 KB) | DOI: 10.20473/mbiom.v29i1.2019.1-6

Abstract

Background: Spine tuberculosis or spondylitis TB is one of the most common found extrapulmonary form of Mycobacterium tuberculosis infection that can be rapidly transmitted. However, people’s alertness are still to be increased and this disease is still rarely investigated. Objective: To study the characteristics of spondylitis tuberculosis patients to enhance the understanding of the disease and improve alertness to its signs and symptoms. Material and method: This study was conducted by assessing patients’ medical records based on particularly the epidemiology, signs and symptoms, radiology and laboratory tests. Collected data were assessed retrospectively and analyzed descriptively. Results: Of 35 patients, most come from early adult age group which is ranged from 26 to 35 years old (25.72%), and 57.14% of the patients were female. Sorted from the most to least common found signs and symptoms are back pain (85.71%), formation of abscess (74.29%), formation of gibbus (54.29%), fever (37.14%), and significant weight loss (34.29%). In radiologic evaluation, spine destruction were found on 82.86% of the patients. Erythrocyte sedimentation rate (ESR) was evaluated from 30 patients, 90% of which had increased ESR to >30 mm/hour. The leukocyte count was based from 35 patients, which result was 71.43% of them had normal count. Conclusions: Spondylitis TB is mostly found in adult females with back pain as the most common symptom. Most patients had spine destruction. Largely had elevated ESR while their leukocyte count mostly remains within normal range.
CLINICAL PROFILE AND INCIDENCE OF INFECTION IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS AT MEDICAL INPATIENT INSTALLATION, DEPARTMENT OF INTERNAL MEDICINE, DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN 2016 Trilistyoati, Desy; Agustina, Betty; Awalia, Awalia
Majalah Biomorfologi Vol 31, No 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.49-56

Abstract

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease with unknown aetiology. SLE attacks multiple organs with diverse clinical manifestations. Most patients get immunosuppressant therapy that suppresses immune system, causing the body to be susceptible to infection. Objective: to describe clinical manifestations, laboratory abnormalities, and incidence of infections in SLE patients hospitalized at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2016. Materials and Methods: Cross-sectional descriptive observational study used medical records of 273 SLE patients hospitalized at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2016. Results: Clinical manifestations found in this study were malar rash 7.33%, discoid rash 2.93%, oral ulcer 8.42%, allopecia 16.48%, arthritis 26.74%, serositis 13.19%, kidney 35.9%, neurology 24.91%, anemia 73.71%, leucopenia 32.67%, lymphopenia 76.89%, and thrombocytopenia 33.86%. Laboratory abnormalities found in this study were hematology (anemia 73.71%, leucopenia 32.67%, lymphopenia 76.89%, thrombocytopenia 33.86%), kidney function (high serum creatinine levels 39.66%, high BUN levels 41.2%, hypoalbuminemia 62.6%), urine (proteinuria 68.21%, hematuria 51.79%) and liver function (high ALT levels 36.65%, high AST levels 29.86%). Infection occurred in 33.7% patients. The most common infections were pneumonia (70.65%), urinary tract infections (51.09%), and sepsis (35.87%). Conclusion: The most common clinical manifestations experienced by SLE patients are hematological disorder, kidney disorder, and arthritis. Prominent laboratory abnormalities are anemia, lymphopenia, and proteinuria. Infection is a common complication, with the most common types pneumonia, urinary tract infection, and sepsis.
LESI MEDULA SPINALIS Maulina, Meutia; Kalanjati, Viskasari Pintoko
Majalah Biomorfologi Vol 26, No 1 (2013): Majalah Biomorfologi
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.066 KB) | DOI: 10.20473/mbiom.v26i1.2013.1-5

Abstract

Spinal cord  lesion  is one of major causes  of neurological  disability  due to  trauma  and non  trauma. Thisdisability can cause damage and loss of function below the level of lesion and also has adversed effects onseveral body systems. Traumatic spinal cord lesion is the most widely reported incidence compared to nontraumatic spinal cord lesion. The most leading cause of traumatic spinal cord lesion is motor vehicle crash in children, whereas in old age, falls become the main cause. The mechanism of injury influences the type of spinal cord lesion and the degree of neurological deficit. Spinal cord lesions can be classified into completeand incomplete based on the presence or absence of a function that is maintained below the level of lesion.Complete spinal cord lesion shows absence of voluntary movement or sensation below the level of the lesionon both sides, whereas incomplete lesion shows the persistence of the variation of some functions below the level of  lesion. Knowledge on the anatomy of the  spinal  cord  plays an important role  in  the clinicaldiagnosis. The  level of  lesion  at the different  segments of  the spinal cord  determines different  signs  andsymptoms, caused by destruction of segmental tissue and disconnection of ascending and descending tracts above and below the level of lesion. The level of lesion is helpful in predicting deficits of body functions thatmay  occur, in  determining  the next  treatment  and in predicting the  prognosis of the disease. Incompletespinal cord lesion tends to have a better prognosis. Death usually occurs in lesion with multiple trauma. Theleading cause of death is complications due to neurological disability, i.e. pneumonia, pulmonary embolism,septicemia, and renal failure.
THE SIMILAR CHANGES OF GLUCOSE LEVELS BEFORE AND AFTER MODERATE INTENSITY EXERCISE ACUTELY IN THE MORNING AND EVENING Kamal, Ronik Harsono; Wigati, Kristanti Wanito; Lefi, Achmad
Majalah Biomorfologi Vol 30, No 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i2.2020.39-44

Abstract

Background: There is a lot of research on the importance of exercise but studies on the effective time of exercise regarding regulation of blood glucose levels are not clearly known. Objective: This study aimed to determine the comparison of changes in blood glucose levels before and after moderate intensity physical exercise in the morning and evening. Materials and Methods: Healthy men (n=34), age between 17-22 years, Body Mass Index (BMI) between 18.5-22.9 kg/m2 (normal Asia Pacific), participating in the morning (8.00 am) or evening group (20.00 pm) are asked to do moderate intensity physical exercise (55-70% of maximum heart rate) using ergocycle for a total of 40 minutes. Blood glucose levels 2 hours post prandial capillaries were taken before exercise and blood glucose levels after exercise were taken acutely. Results: The mean decrease in blood glucose levels in the morning group was ± 8.353 ± 9.16 mg/dL and in the evening group was ± 6.294 ± 10.10 mg/dL. Blood glucose levels decreased significantly for the morning group (p=0.002) and the evening group (p=0.021). The comparison of changes in blood glucose levels between the morning and evening groups was not significant (p=0.538). Conclusion: There was no difference between morning or evening exercise related to changes in blood glucose levels.
PERBEDAAN JUMLAH LIMFOSIT DAERAH PALS (PERIARTERIAL LYMPHOID SHEAT) ANTARA MENCIT SEHAT DAN MENCIT DIABETES Dewi, Arni Kusuma; Rahardjo, Iskantijah Budi; Gunawan, Ari
Majalah Biomorfologi Vol 27, No 1 (2014): Majalah Biomorfologi
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.715 KB) | DOI: 10.20473/mbiom.v27i1.2014.5-8

Abstract

Diabetes mellitus complication that much happen and need attention is infection. Bacterial infection getting worse with the decrease of cellular immunity diabetic patient. Antibiotic treatment has not been optimaly yet without immunity intervention to the patient. This study is done to evaluate immunity state in diabetes with count lymphocyte in PALS spleen then compare with healthy ones. Thirty six mice BALB/c strain, sex male ware separated into 2 groups, the control group and the treatment group. The control groups were healty and had standart diet, while the treatment groups were diabetic group and had high fat diet to induct diabetes for ten weeks. After 10 weeks, both groups were induced with histamine intraperitoneally to show immune respons. Mice were sacrified for taken the spleen to make histology preparation with routine staining. Account of lymphocyte both groups compared with statistical tools by t test independent samples. Account of lymphocyte cell in the PALS area shown that the control had significant more than the treatment (p<0,0001). Smaller number of lymphocyte in diabetic is one of the proofs that there are decrease of immunity.
Back Matter vol. 31 no. 2 July 2021 Biomorfologi, Majalah
Majalah Biomorfologi Vol 31, No 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga

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Abstract

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