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Parapemikir : Jurnal Ilmiah Farmasi
ISSN : 20895313     EISSN : 25495062     DOI : -
Parapemikir : Jurnal Ilmiah Farmasi (PJIF) invites manuscripts in the various topics include, Health Sciences, Life Sciences, Social Sciences and Humanities .
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Articles 8 Documents
Search results for , issue "Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi" : 8 Documents clear
Evaluasi Perilaku Penggunaan Obat Sebelum Pasien Terdiagnosa Penyakit Ginjal Kronis Di Rsud Soesilo Kabupaten Tegal Dan Rsud Kardinah Kota Tegal Periode Januari – Agustus 2016 kamal, khusny
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.2027

Abstract

The number of people with Chronic Kidney Disease (CKD) continues to increase and is considered as one of the health problems that can develop into an epidemic. Increasing the use of over the counter (OTC) products, the use of traditional medicines mixed with medicinal chemicals, the use of hard drugs freely brings concerns and concerns about the quality, effectiveness, safety of the products used. This study aims to look at patient distribution, drug use behavior before being diagnosed with CKD in Soeselo Regional Hospital and Kardinah Regional Hospital. The method used in this study is cross sectional by giving prospective questionnaires to patients who fall into the inclusion criteria. The sample used was chronic kidney patients undergoing treatment at Soeselo Regional Hospital as many as 56 respondents and 138 respondents at the Kardinah Regional Hospital in the period January 2016 - August 2016. Data were analyzed statistically using the chi square test to see the proportion of CKD distribution and behavior of drug use of patients in the Regional Hospital Soeselo with Kardinah Regional Hospital. Based on the results of the study, the demographic characteristics obtained male sex, age> 50 years, the type of occupation with moderate physical activity is a high proportion in Kardinah Regional Hospital while the distribution of education level is the highest proportion in Soeselo Regional Hospital. the most widely used is pain reliever (42.6%), where there are significant behavioral differences in Soeselo Regional Hospital with Kardinah Regional Hospital on the behavior of using herbal medicine in racik at home and in the holding of herbal medicine where the proportion of usage in Kardinah Regional Hospital is much higher than in Soesilo Regional Hospital p-value (p <0.05) while the most widely used drugs or health supplements are herbal medicine packaging at home (22.6%) and no significant differences were found (p> 0.05) for supplement use behavior health to maintain stamina and health in both hospitals.
Identifikasi Kulit Batang Kalangkala (Litsea Angulata Bi) Secara Makroskopik, Mikroskopik, Dan Skrining Fitokimia Fitriyanti, Fitriyanti; Qalbiyah, Syamratul; Sayakti, Putri Indah
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.1832

Abstract

Kalangkala (Litsea angulata BI) merupakan salah satu spesies dari genus Litsea dan tergolong dalam keluarga Lauraceae. Sebagian masyarakat Kalimantan Selatan telah menggunakan tumbuhan Kalangkala dalam beragam pengobatan tradisional, seperti bagian kulit batangnya yang secara empiris berkhasiat untuk anti iritan. Penelitian ini bertujuan untuk memberikan data ilmiah mengenai gambaran farmakognostik secara kualitatif dengan beberapa tahapan pemeriksaan organoleptik, makroskopik, mikroskopik, ekstraksi, dan skrining fitokimia. Pada pemeriksaan organoleptik kulit batang Kalangkala segar yaitu berwarna hijau, terasa agak pahit, dan bau khas lemah. Sementara serbuk simplisianya berwarna cokelat muda, rasa pahit agak kelat, dan berbau khas agak menyengat. Hasil pemeriksaan makroskopik kulit batang Kalangkala berbentuk tipis dan lunak, ketebalannya sekitar ± 3 mm, tekstur permukaan luar kulit batang Kalangkala memiliki tipe halus namun agak kasap dan bagian permukaan dalam teraba licin juga berlendir. Pada pemeriksaan mikroskopik terdapat epidermis, vakuola, kloroplas, sel batu, hablur kalsium oksalat, serat lumen, dan jaringan gabus. Ekstrak diperoleh dari maserasi simplisia menggunakan pelarut etanol 70%. Hasil skrining fitokimia menunjukkan bahwa serbuk simplisia dan ekstrak kental kulit batang Kalangkala mengandung metabolit sekunder berupa alkaloid, flavonoid, tanin, dan saponin.
Formulasi Krim Ekstrak Daun Kersen (Muntingia calabura L.) Dengan Variasi Kombinasi Span 60 dan Tween 80 Sebagai Emulgator Anindhita, Metha Anung; Arsanto, Catur Juni
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.2034

Abstract

The ethanol extract of 1,04% Muntingia calabura L. folium has the effectiveness of healing burns. An emulgator is needed to maintain the stability of the cream formulation. Span 60 and tween 80 are non-ionic emulgators, non-toxic, non-irritating, and have low potential to couse hypersensitivity reactions. This research was conducted to determine the effect of the emulgator on physical properties and physical stability of Muntingia calabura L. folium extract cream and get the best formula from the cream. This study was compare the value of Hydrophile-Lipophile Balances (HLB) from a mixture of span 60 and tween 80, which is the HLB value of 5; HLB 6.5 and HLB 8. Evaluation of physical properties is done by testing organoleptic, homogeneity, pH, viscosity, adhesion, and ability to spread. Physical stability was assessed using the centrifugation method. The effect of emulgator variations was determined by One Way Anova testing using SPSS software. The best formula is chosen from those that fit the criteria for testing physical properties and which has the best stability. The results showed different variations in the combination of span 60 and tween 80 emulgators showed effects on adhesion and pH. Formula I with HLB value of 5 produces a cream formula with good physical properties and physical stability
Analisis Pengaruh Obat Antituberkulosis Terhadap Nilai Sgpt dan Sgot pada Pasien Penderita Tuberkulosis Paru Hasanah, Nur; Novian, Dede Rival
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.1881

Abstract

Tuberculosis (TB) is a direct infectious disease caused by Mycobacterium tuberculosis. Anti-tuberculosis drugs have a hepatotoxic effect that causes extensive liver injury and harvesters. The parameter to determine the presence or absence of liver damage is to look at SGPT and SGOT levels. The purpose of this study was to determine the effect of drugs on SGPT and SGOT values based on age and sex classification. The method is carried out with a retrospective approach. The results showed that the effect of drugs on the value of SGPT with a high value of> 35 as much as 6.25%, on the value of SGOT with a high value> 35 as much as 12.5%. Whereas at the age of 56-65 years the SGPT value was 2.5% and SGOT was 3.75%, at the age of 17-25 years the SGOT value was 3.75%. sex with a high SGPT score of 5%. While the SGOT value is equal to 6.25%. Then it can be concluded that the administration of anti-tuberculosis drugs to the value of SGPT and SGOT has an effect on the value of SGPT and SGOT based on age is productive age which is 15-49 years whereas based on gender is men.
Formulasi Micellar Based Water Ekstrak Bunga Telang Dzakwan, Muhammad
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.2043

Abstract

Clitoria ternatea is a twining herbal medicinal plant. It has pharmacological activity as antioxidant, anticancer and anti depressant. Extracts of C ternatea flowers were used as a component of cosmetics. The aim of this research is to formulate and develop micellar based water with variation concentration of amphiphilic polymer. Results showed that formulation containing amphiphilic polymer 1% (F5) is the most stable, clearly, particle size distribution of 46,67 nm and zeta potential -18,4 mV was obtained. Conclution, extracts of C ternatea flowers successfully formulaed to  micellar based water, antioxidant activity (IC50) of 1,30 mg/ml was obtained.
Pola Penggunaan Obat Pada Pasien Dispepsia Rawat Jalan Di RSUD H.Abdul Manap Kota Jambi mulandani, restu gusti
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.1885

Abstract

ABSTRAK Dispepsia merupakan salah satu masalah pencernaan yang paling umum ditemukan di masyarakat. Gejala yang dirasakan seperti nyeri ulu hati, mual, muntah, nafsu makan berkurang, sendawa dan rasa cepat kenyang. Penelitian ini bertujuan untuk mengetahui pola penggunaan obat dispepsia pada pasien rawat jalan tahun 2017-2018 di Rumah Sakit Umum Daerah H. Abdul Manap Kota Jambi berdasarkan nama obat, jumlah obat perpasien, bentuk sediaan dan golongan obat. Penelitian ini merupakan penelitian deskriptif dengan menggunakan studi evaluasi pada data retrospektif dilakukan pada bulan Agustus 2019, data diperoleh dari rekam medik pasien dispepsia rawat jalan di Rumah Sakit Umum Daerah H. Abdul Manap Kota Jambi tahun 2017-2018 dengan metode purposive sampling. Data yang diperoleh disajikan dalam bentuk persentase, nilai rata-rata dan tabel. Hasil penelitian menunjukkan sebanyak 76 pasien tahun 2017 dan 81 pasien tahun 2018. Penyakit dispepsia paling banyak terjadi pada perempuan (69,74%) tahun 2017, (69,14%) tahun 2018 dan pada usia 45-60 tahun (43,42%) tahun 2017, (44,44%) tahun 2018. Sediaan obat yang paling banyak digunakan tablet (65,97%) tahun 2017, (66,10%) tahun 2018. Berdasarkan golongan obat Pump Proton Inhibitor (Lansoprazole, Omeprazole) 50,66% tahun 2017, 48,28% tahun 2018 yang paling banyak digunakan untuk pengobatan dispepsia dengan manifestasi klinik yang paling banyak ditemukan yaitu nyeri epigastrium 27,63% tahun 2017, 23,46% tahun 2018. 
Evaluasi Legalitas Dan Kelengkapan Administratif Resep Pada Rumah Sakit di Kabupaten Brebes Fajarini, Hanari
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.1969

Abstract

Penelaahan legalitas dan kelengkapan administratif dalam resep dapat mengurangi atau bahkan mencegah terjadinya kesalahan pengobatan atau medication errors, yaitu kejadian yang dapat mengakibatkan kerugian kepada pasien akibat dari pemakaian obat yang kurang tepat selama dalam penanganan tenaga kesehatan. Penelitian ini bertujuan untuk mengevaluasi kelengkapan administratif resep yang merupakan aspek legal dari suatu resep, dengan mengkaji kemungkinan terjadinya kesalahan pengobatan dari dokter penulis resep. Penelitian ini merupakan penelitian kualitatif dengan menggunakan metode analisis data deskriptif, pengambilan sampel dilakukan secara snowball method. Terdapat 267 lembar resep yang diteliti selama periode dari tanggal 7, 8, 9, 10, 11, 14 dan 15 Agustus 2017 kemudian dievaluasi kelengkapan administratifnya. Kelengkapan administratif resep yang dituliskan oleh dokter pada resep, yakni nama pasien (100%), jenis kelamin (100%), umur pasien (0%), alamat pasien (98.8%), nama dokter (97.1%), nomor Surat Ijin Praktek dokter (42.3%), alamat dokter (0%), paraf dokter (0%), tanggal peresepan (95.8%), berat badan pasien (0%). Dari data yang diperoleh, sebagian besar resep telah memenuhi kriteria legalitas dan kelengkapan administratif resep sebagaimana termuat dalam Peraturan Menteri Kesehatan Republik Indonesia Nomor 72 Tahun 2016 Tentang Standar Pelayanan Kefarmasian di Rumah Sakit
Uji Antibakteri Kombinasi Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L) Dan Daun Kersen (Muntingia calabura L) Terhadap Staphylococcus aureus Pramiastuti, Oktariani; Rejeki, Desi Sri; Maghfiroh, Inul
Parapemikir : Jurnal Ilmiah Farmasi Vol 9, No 2 (2020): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v9i2.2026

Abstract

Infectious diseases are one of the main causes of diseases in tropical regions like Indonesia. Infectious diseases usually can be cured by antibiotics, since the use of antibiotics has side effects and long-term resistance and prices that are not affordable, it needs a role of herbs that can weaken the activity of these bacteria. Kersen plants contains various chemical compounds namely flavonoid compounds, saponins, and tannins that have antioxidant potential and antibacterial activity. Belimbing wuluh contains flavonoid compounds. This research was conducted to find out the antibacterial activity of extract combination of kersen leaf (Muntingia calabura L) and belimbing wuluh leaf (Averrhoa bilimbi L) against Staphylococcus aureus. Extract of Kersen leaf and Belimbing wuluh leaf were obtained by maceration method using ethanol 96% for 5 days. The antibacterial activity test was performed by diffusion method using disc paper based on the inhibit zone diameter or clear zone formed around the disc paper. The test was conducted by extract comparison of kersen leaf and belimbing wuluh leaf at 30% concentration namely 1:1, 1:2, 2:1, 1:3 and 3:1 against Staphylococcus aureus. The results showed that the extract comparison of kersen leaf and belimbing wuluh leaf 1:1 had a weak inhibitory power because of its inhibitory value ≤ 5 mm, that was 4.67 mm. While the ratio of 1:2, 2:1, 1:3 and 3:1 had a moderate inhibition resistance value ranges from 5-10 mm; 6.33 mm,7.16 mm, 7.67 mm, and 7.83 mm. Extract rendemen of kersen leaf was 11.94% and belimbing wuluh leaf was 6.28%.

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